Advanced search
Publication Cover
Clinical Toxicology Volume 58, 2020 - Issue 2
Submit an article Journal homepage
1,708
Views
16
CrossRef citations to date
0
Altmetric
Short Communications

Toxicity induced by multiple high doses of vitamin B12 during pernicious anemia treatment: a case report

Jessica Morales-GutierrezCIEMTO [Drug and Poison Research and Information Center], Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia
,
Sebastián Díaz-CortésCIEMTO [Drug and Poison Research and Information Center], Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia
,
María A. Montoya-GiraldoCIEMTO [Drug and Poison Research and Information Center], Facultad de Medicina, Universidad de Antioquia, Medellín, ColombiaORCID Iconhttp://orcid.org/0000-0002-3756-0074
ORCID Icon &
Andres F. ZuluagaCIEMTO [Drug and Poison Research and Information Center], Facultad de Medicina, Universidad de Antioquia, Medellín, ColombiaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-5656-4153
ORCID Icon
Pages 129-131 | Received 04 Jan 2019, Accepted 03 Apr 2019, Published online: 24 Apr 2019

References

  • Green R. Vitamin B12 deficiency from the perspective of a practicing hematologist. Blood. 2017;129:2603–2611.
  • Andres E, Loukili NH, Noel E, et al. Vitamin B12 (cobalamin) deficiency in elderly patients. CMAJ. 2004;171:251–259.
  • Zulfiqar AA, Andres E. Association pernicious anemia and autoimmune polyendocrinopathy: a retrospective study. J Med Life. 2017;10:250–253.
  • Fenech M. The role of folic acid and Vitamin B12 in genomic stability of human cells. Mutat Res. 2001;475:57–67.
  • Andres E, Serraj K, Zhu J, et al. The pathophysiology of elevated vitamin B12 in clinical practice. QJM. 2013;106:505–515.
  • B-12 COMPLIANCE- cyanocobalamin, isopropyl alcohol [package insert]. American regent, INC., Shirley, NY. 2018.
  • Glass GB, Skeggs HR, Lee DH, Hydroxocobalamin V. Prolonged maintenance of high vitamin B12 blood levels following a short course of hydroxocobalamin injections. Blood. 1966;27:234–241.
  • Shankar PR. VigiAccess: promoting public access to VigiBase. Indian J Pharmacol. 2016;48:606–607.
  • Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol. 2014;33:94–95.
  • Bettoli V, Zauli S, Montis A, et al. Acneiform eruption due to vitamin B12: a problem still unsolved. G Ital Dermatol Venereol. 2014;149:153–155.
  • Tillemans MP, Donders EM, Verweij SL, et al. Effect of administration route on the pharmacokinetics of cobalamin in elderly patients: a randomized controlled trial. Curr Ther Res Clin Exp. 2014;76:21–25.
  • Kang D, Shi B, Erfe MC, et al. Vitamin B12 modulates the transcriptome of the skin microbiota in acne pathogenesis. Sci Transl Med. 2015;7:293ra103.
  • Neely MN, van Guilder MG, Yamada WM, et al. Accurate detection of outliers and subpopulations with Pmetrics, a nonparametric and parametric pharmacometric modeling and simulation package for R. Ther Drug Monit. 2012;34:467–476.
  • Neely M, Philippe M, Rushing T, et al. Accurately achieving target busulfan exposure in children and adolescents with very limited sampling and the BestDose software. Ther Drug Monit. 2016;38:332–342.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.