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Clinical Toxicology Volume 58, 2020 - Issue 12
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Letters in Response & Replies

Comment on Antidotal use of lipid emulsion – the pendulum swings

Robert S. HoffmanDivision of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU Grossman School of Medicine, New York, NY, USA; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-0091-9573
ORCID Icon,
Sophie GosselinDepartment of Medicine & Emergency Medicine, McGill University Health Centre, Royal Victoria Hospital, Montreal, QC, Canada; ;Hôpital Charles-Lemoyne, Greenfield Park, QC, Canada; ORCID Iconhttp://orcid.org/0000-0002-0694-5588
ORCID Icon,
Eric VilleneuveDepartment of Pharmacy, McGill University Health Centre, Montreal, QC, Canada; ORCID Iconhttp://orcid.org/0000-0003-0510-8144
ORCID Icon,
Bryan D. HayesDepartment of Pharmacy, Massachusetts General Hospital, Boston, MA, USA; ;Department of Emergency Medicine, Harvard Medical School, Boston, MA, USA; ORCID Iconhttp://orcid.org/0000-0001-7349-6770
ORCID Icon,
Lotte C. G. HoegbergDepartment of Anesthesiology, and The Danish Poisons Information Centre, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark; ORCID Iconhttp://orcid.org/0000-0003-0252-2470
ORCID Icon &
Susan C. SmolinskeNew Mexico Poison & Drug Information Center, University of New Mexico, Albuquerque, NM, USA
Pages 1355-1356 | Received 17 Apr 2020, Accepted 20 Apr 2020, Published online: 13 May 2020

References

  • Mullins ME, Seger DL. Antidotal use of lipid emulsion – the pendulum swings. Clin Toxicol. 2020;:1–3.
  • Hoegberg LC, Bania TC, Lavergne V, Lipid Emulsion Workgroup, et al. Systematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity. Clin Toxicol (Philadelphia, PA). 2016;54(3):167–193.
  • Harvey M, Cave G, Shaw T. Effect of intravenous lipid emulsion and octreotide on enteric thiopentone absorption: a pilot study. Clin Toxicol (Philadelphia, PA). 2013;51(2):117–118.
  • Perichon D, Turfus S, Gerostamoulos D, et al. An assessment of the in vivo effects of intravenous lipid emulsion on blood drug concentration and haemodynamics following oro-gastric amitriptyline overdose. Clin Toxicol (Philadelphia, PA). 2013;51(4):208–215.
  • Perichon D, Turfus S, Gerostamoulos D, et al. Intravenous lipid emulsion does not improve hemodynamics or survival in a rodent model of oral verapamil poisoning. Clin Toxicol. 2013;51(4):208–215.
  • Kasnavieh FH, Kasnavieh MH, Noddoushan SJ, et al. Intravenous lipid emulsion for the treatment of tricyclic antidepressant toxicity a randomized controlled trial. VIIth Mediterranean Emergency Medicine Congress 2013. Marseille, France.
  • Taftachi F, Sanaei-Zadeh H, Sepehrian B, et al. Lipid emulsion improves Glasgow coma scale and decreases blood glucose level in the setting of acute non-local anesthetic drug poisoning: a randomized controlled trial. Eur Rev Med Pharmacol Sci. 2012;16 (Suppl 1):38–42.
  • Sirianni AJ, Osterhoudt KC, Calello DP, et al. Use of lipid emulsion in the resuscitation of a patient with prolonged cardiovascular collapse after overdose of bupropion and lamotrigine. Annal Emer Med. 2008;51(4):412–415.
  • Cole JB, Stellpflug SJ, Engebretsen KM. Asystole immediately following intravenous fat emulsion for overdose. J Med Toxicol. 2014;10(3):307–310.
  • Hayes BD, Gosselin S, Calello DP, Lipid Emulsion Workgroup, et al. Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration. Clin Toxicol (Philadelphia, PA). 2016;54(5):365–404.
  • Levine M, Hoffman RS, Lavergne V, for the Lipid Emulsion Workgroup, et al. Systematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity. Clin Toxicol (Philadelphia, PA). 2016;54(3):194–221.
  • Grunbaum AM, Gilfix BM, Hoffman RS, et al. Review of the effect of intravenous lipid emulsion on laboratory analyses. Clin Toxicol (Philadelphia, PA). 2016;54(2):92–102.
  • Gosselin S, Hoegberg LC, Hoffman RS, et al. Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning. Clin Toxicol (Philadelphia, PA). 2016;54(10):899–923.
  • Smolinske S, Hoffman RS, Villeneuve E, et al. Utilization of lipid emulsion therapy in fatal overdose cases: an observational study. Clin Toxicol (Philadelphia, PA). 2019;57(3):197–202.

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