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Clinical Toxicology Volume 59, 2021 - Issue 11
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Increase in pregabalin recreational use in adolescents in France

Laurene Dufayeta Unité Médico-Judiciaire, Assistance Publique des Hôpitaux de Paris – Hôtel Dieu, Paris, France;b UFR de médecine, Université de Paris, Paris, France;c Faculté de Pharmacie de Paris, INSERM UMRS 1144, Paris, France;d Centre antipoison et de Toxicovigilance de Paris, Assistance Publique des Hôpitaux de Paris – Hôpital Fernand Widal, Paris, France
,
Weniko Carec Faculté de Pharmacie de Paris, INSERM UMRS 1144, Paris, France;d Centre antipoison et de Toxicovigilance de Paris, Assistance Publique des Hôpitaux de Paris – Hôpital Fernand Widal, Paris, France;e Service de médecine interne, Service de Santé des armées – Hôpital d'Instruction des Armées Bégin, Saint-Mandé, France
,
Sylvie Deheulf Centre antipoison et de Toxicovigilance de Lille, CHU de Lille, Lille Cedex, France
,
Hervé Laborde-Casterotd Centre antipoison et de Toxicovigilance de Paris, Assistance Publique des Hôpitaux de Paris – Hôpital Fernand Widal, Paris, France
,
Patrick Nissef Centre antipoison et de Toxicovigilance de Lille, CHU de Lille, Lille Cedex, France
, French PCC Research Group,
Jerome Langrandc Faculté de Pharmacie de Paris, INSERM UMRS 1144, Paris, France;d Centre antipoison et de Toxicovigilance de Paris, Assistance Publique des Hôpitaux de Paris – Hôpital Fernand Widal, Paris, FranceORCID Iconhttps://orcid.org/0000-0002-2123-2885
ORCID Icon &
Dominique Vodovarb UFR de médecine, Université de Paris, Paris, France;c Faculté de Pharmacie de Paris, INSERM UMRS 1144, Paris, France;d Centre antipoison et de Toxicovigilance de Paris, Assistance Publique des Hôpitaux de Paris – Hôpital Fernand Widal, Paris, FranceCorrespondence[email protected]
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Pages 1027-1030 | Received 13 Jan 2021, Accepted 13 Feb 2021, Published online: 18 Mar 2021

References

  • Lyrica – Pregabalin – European Medicines Agency [Internet]. Amsterdam (Netherlands): European Medicines Agency; 2020. Available from: https://www.ema.europa.eu/en/medicines/human/EPAR/lyrica
  • Evoy KE, Morrison MD, Saklad SR. Abuse and misuse of pregabalin and gabapentin. Drugs. 2017;77(4):403–426.
  • Persson HE, Sjöberg GK, Haines JA, et al. Poisoning severity score. Grading of acute poisoning. J Toxicol Clin Toxicol. 1998;36(3):205–213.
  • Schifano F. Misuse and abuse of pregabalin and gabapentin: cause for concern? CNS Drugs. 2014;28(6):491–496.
  • Isoardi KZ, Polkinghorne G, Harris K, et al. Pregabalin poisoning and rising recreational use: a retrospective observational series. Br J Clin Pharmacol. 2020;86(12):2435–2440.
  • Dufayet L, Monnet F, Laborde-Casterot H, et al. Unintentional exposure to pregabalin in ≤6-year-old children: a nationwide French Poison Control Center study. Clin Toxicol. 2020;2:1–7.
  • Millar J, Sadasivan S, Weatherup N, et al. Lyrica nights-recreational pregabalin abuse in an urban emergency department. Emerg Med J. 2013;30(10):872–874.
  • Lyndon A, Audrey S, Wells C, et al. Risk to heroin users of polydrug use of pregabalin or gabapentin. Addiction. 2017;112(9):1580–1589.
  • Nahar LK, Murphy KG, Paterson S. Misuse and mortality related to gabapentin and pregabalin are being under-estimated: a two-year post-mortem population study. J Anal Toxicol. 2019;43(7):564–570.

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