Extracorporeal membrane oxygenation use in poisoning: a narrative review with clinical recommendations

References

• Gummin DD, Mowry JB, Beuhler MC, et al. 2019 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 37th annual report. Clin Toxicol. 2020;58(12):1360–1541.
   PubMed Web of Science ®Google Scholar
• Weiner L, Mazzeffi MA, Hines EQ, et al. Clinical utility of venoarterial-extracorporeal membrane oxygenation (VA-ECMO) in patients with drug-induced cardiogenic shock: a retrospective study of the Extracorporeal Life Support Organizations’ ECMO case registry. Clin Toxicol. 2020;58(7):705–710.
   PubMed Web of Science ®Google Scholar
• Cole JB, Olives TD, Ulici A, et al. Extracorporeal membrane oxygenation for poisonings reported to U.S. poison centers from 2000 to 2018: an analysis of the National Poison Data System. Crit Care Med. 2020;48(8):1111–1119.
   PubMed Web of Science ®Google Scholar
• Derlet RW, Horowitz BZ. Cardiotoxic drugs. Emerg Med Clin North Am. 1995;13(4):771–791.
   PubMedGoogle Scholar
• Koch R, Sun C, Minns A, et al. Overdose of cardiotoxic drugs. In: Brown DL, editor. Cardiac intensive care. 3rd ed. Philadelphia (PA): Elsevier; 2019. p. 351–366.
   Google Scholar
• Morrison LK, Kromm J, Gaudet J, et al. Rescue extracorporeal membrane oxygenation therapy in methamphetamine toxicity. CJEM. 2018;20(S2):S14–S19.
   PubMedGoogle Scholar
• Morimont P, Lambermont B, Gaspard V, et al. Molding thrombus of an ECMO cannula floating in the right atrium. Intensive Care Med. 2015;41(11):1965–1966.
   PubMed Web of Science ®Google Scholar
• Amraotkar AR, Pachika A, Grubb KJ, et al. Rapid extracorporeal membrane oxygenation overcomes fulminant myocarditis induced by 5-fluorouracil. Tex Heart Inst J. 2016;43(2):178–182.
   PubMed Web of Science ®Google Scholar
• Howell E, Paivanas N, Stern J, et al. Treatment of acute necrotizing eosinophilic myocarditis with immunosuppression and mechanical circulatory support. Circ Heart Failure. 2016;9(12):e003665.
   PubMed Web of Science ®Google Scholar
• Beyls C, Huette P, Guilbart M, et al. An urgent open surgical approach for left ventricle venting during peripheral veno-arterial extracorporeal membrane oxygenation for refractory cardiac arrest: case report. Perfusion. 2020;35(1):82–85.
   PubMed Web of Science ®Google Scholar
• Lo MH, Huang CF, Chang LS, et al. Drug reaction with eosinophilia and systemic symptoms syndrome associated myocarditis: a survival experience after extracorporeal membrane oxygenation support. J Clin Pharm Ther. 2013;38(2):172–174.
   PubMed Web of Science ®Google Scholar
• Geng S, Hao X, Xu H, et al. Cardiac injury after acute carbon monoxide poisoning and its clinical treatment scheme. Exp Ther Med. 2020;20(2):1098–1104.
   PubMed Web of Science ®Google Scholar
• Gurjar M, Baronia AK, Azim A, et al. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011;4(3):378–384.
   PubMedGoogle Scholar
• Gorguner M, Akgun M. Acute inhalation injury. Eurasian J Med. 2010;42(1):28–35.
   PubMedGoogle Scholar
• Shah A, Pasrija C, Kronfli A, et al. Veno-venous extracorporeal membrane oxygenation use in the treatment of bleomycin pulmonary toxicity. Innovations. 2017;12(2):144–146.
   PubMedGoogle Scholar
• Wolkove N, Baltzan M. Amiodarone pulmonary toxicity. Can Respir J. 2009;16(2):43–48.
   PubMed Web of Science ®Google Scholar
• Radke JB, Owen KP, Sutter ME, et al. The effects of opioids on the lung. Clin Rev Allergy Immunol. 2014;46(1):54–64.
   PubMed Web of Science ®Google Scholar
• Jiwa N, Sheth H, Silverman R. Naloxone-induced non-cardiogenic pulmonary edema: a case report. Drug Saf Case Rep. 2018;5(1):20–20.
   PubMedGoogle Scholar
• Tseng W, Sutter ME, Albertson TE. Stimulants and the lung: review of literature. Clin Rev Allergy Immunol. 2014;46(1):82–100.
   PubMed Web of Science ®Google Scholar
• King JD, Kern MH, Jaar BG. Extracorporeal removal of poisons and toxins. Clin J Am Soc Nephrol. 2019;14(9):1408–1415.
   PubMed Web of Science ®Google Scholar
• Fertel BS, Nelson LS, Goldfarb DS. Extracorporeal removal techniques for the poisoned patient: a review for the intensivist. J Intensive Care Med. 2010;25(3):139–148.
   PubMedGoogle Scholar
• Gil HW, Kim SJ, Yang JO, et al. Clinical outcome of hemoperfusion in poisoned patients. Blood Purif. 2010;30(2):84–88.
   PubMed Web of Science ®Google Scholar
• Ferrari F, Carletti A, Peroni N, et al. Brief report: a case of tramadol overdose: extracorporeal life support and hemoperfusion as life-saving treatment. Blood Purif. 2020;49(4):509–512.
   PubMed Web of Science ®Google Scholar
• Brogan TV, Annich G, Ellis WC, et al., editors. ECMO specialist training manual. 4th ed. Ann Arbor (MI): Extracorporeal Life Support Organization (ELSO); 2018.
   Google Scholar
• Firstenberg MS. Contraindications to extracorporeal membrane oxygenation: are there any absolutes? J Am Soc Echocardiogr. 2012;25(6):698.
   PubMed Web of Science ®Google Scholar
• Combes A, Price S, Slutsky AS, et al. Temporary circulatory support for cardiogenic shock. Lancet. 2020;396(10245):199–212.
   PubMed Web of Science ®Google Scholar
• Brodie D, Slutsky AS, Combes A. Extracorporeal life support for adults with respiratory failure and related indications: a review. JAMA. 2019;322(6):557–568.
   PubMed Web of Science ®Google Scholar
• International Complication Trend Report. Ann Arbor (MI): ECLS Registry of the Extracorporeal Life Support Organization (ELSO); 2020.
   Google Scholar
• Masson R, Colas V, Parienti J-J, et al. A comparison of survival with and without extracorporeal life support treatment for severe poisoning due to drug intoxication. Resuscitation. 2012;83(11):1413–1417.
   PubMed Web of Science ®Google Scholar
• Megarbane B, Leprince P, Deye N, et al. Emergency feasibility in medical intensive care unit of extracorporeal life support for refractory cardiac arrest. Intensive Care Med. 2007;33(5):758–764.
   PubMed Web of Science ®Google Scholar
• Brunet J, Valette X, Ivascau C, et al. Extracorporeal life support for refractory cardiac arrest or shock: a 10-year study. ASAIO J. 2015;61(6):676–681.
   PubMed Web of Science ®Google Scholar
• Daubin C, Lehoux P, Ivascau C, et al. Extracorporeal life support in severe drug intoxication: a retrospective cohort study of seventeen cases. Crit Care. 2009;13(4):R138.
   PubMed Web of Science ®Google Scholar
• Shin TG, Jo IJ, Sim MS, et al. Two-year survival and neurological outcome of in-hospital cardiac arrest patients rescued by extracorporeal cardiopulmonary resuscitation. Int J Cardiol. 2013;168(4):3424–3430.
   PubMed Web of Science ®Google Scholar
• Aso S, Matsui H, Fushimi K, et al. In-hospital mortality and successful weaning from venoarterial extracorporeal membrane oxygenation: analysis of 5,263 patients using a national inpatient database in Japan. Crit Care. 2016;20(1):80.
   PubMed Web of Science ®Google Scholar
• Mohan B, Gupta V, Ralhan S, et al. Impact of extra-corporeal membrane oxygenation on outcome of aluminium phosphide poisoning complicated with myocardial dysfunction. Clin Toxicol. 2019;57(11):1095–1102.
   PubMed Web of Science ®Google Scholar
• Wang GS, Levitan R, Wiegand TJ, et al. Extracorporeal membrane oxygenation (ECMO) for severe toxicological exposures: review of the toxicology investigators consortium (ToxIC). J Med Toxicol. 2016;12(1):95–99.
   PubMed Web of Science ®Google Scholar
• Radowsky JS, Mazzeffi MM, Deatrick KB, et al. Intoxication and overdose should not preclude veno-venous extracorporeal membrane oxygenation. Perfusion. 2020 [10 October]. doi:https://doi.org/10.1177/0267659120963938
   Google Scholar
• Ramanathan K, Tan CS, Rycus P, et al. Extracorporeal membrane oxygenation for poisoning in adult patients: outcomes and predictors of mortality. Intensive Care Med. 2017;43(10):1538–1539.
   PubMed Web of Science ®Google Scholar
• Mu H-W, Chen CH, Yang K-W, et al. Cerbera manghas poisoning survived by using extracorporeal life support. Clin Toxicol. 2018;56(2):153–154.
   Web of Science ®Google Scholar
• Thooft A, Goubella A, Fagnoul D, et al. Combination of veno-arterial extracorporeal membrane oxygenation and hypothermia for out-of-hospital cardiac arrest due to Taxus intoxication. CJEM. 2014;16(6):504–507.
   PubMedGoogle Scholar
• Haas NA, Wegendt C, Schaffler R, et al. ECMO for cardiac rescue in a neonate with accidental amiodarone overdose. Clin Res Cardiol. 2008;97(12):878–881.
   PubMed Web of Science ®Google Scholar
• Rona R, Cortinovis B, Marcolin R, et al. Extra-corporeal life support for near-fatal multi-drug intoxication: a case report. J Med Case Rep. 2011;5:231.
   PubMedGoogle Scholar
• Sood SB, Banner W, Barton RP. Extracorporeal cardiopulmonary resuscitation after brown recluse envenomation. Clin Toxicol. 2017;55(5):368–369.
   PubMed Web of Science ®Google Scholar
• Vivien B, Deye N, Megarbane B, et al. Extracorporeal life support in a case of fatal flecainide and betaxolol poisoning allowing successful cardiac allograft. Ann Emerg Med. 2010;56(4):409–412.
   PubMed Web of Science ®Google Scholar
• Kolcz J, Pietrzyk J, Januszewska K, et al. Extracorporeal life support in severe propranolol and verapamil intoxication. J Intensive Care Med. 2007;22(6):381–385.
   PubMedGoogle Scholar
• Bhimani SA, Rao S, Nadorlik H, et al. Flecainide toxicity in renal tubular acidosis type IV treated with extracorporeal membrane oxygenation. HeartRhythm Case Rep. 2020;6(5):287–289.
   PubMedGoogle Scholar
• Sivalingam SK, Gadiraju VT, Hariharan MV, et al. Flecainide toxicity-treatment with intravenous fat emulsion and extra corporeal life support. Acute Card Care. 2013;15(4):90–92.
   PubMedGoogle Scholar
• Kwan D, Vohra R, Dyer JE, et al. An infant with a heartbreaking medication error. Pediatr Emerg Care. 2014;30(12):e1–e5.
   PubMed Web of Science ®Google Scholar
• Ishigami S, Hase S, Nakashima H, et al. Intravenous chlorhexidine gluconate causing acute respiratory distress syndrome. J Toxicol Clin Toxicol. 2001;39(1):77–80.
   PubMed Web of Science ®Google Scholar
• Chenoweth JA, Colby DK, Sutter ME, et al. Massive diltiazem and metoprolol overdose rescued with extracorporeal life support. Am J Emerg Med. 2017;35(10):1581.e3–1581.e5.
   Web of Science ®Google Scholar
• Shenoi AN, Gertz SJ, Mikkilineni S, et al. Refractory hypotension from massive bupropion overdose successfully treated with extracorporeal membrane oxygenation. Pediatr Emerg Care. 2011;27(1):43–45.
   PubMed Web of Science ®Google Scholar
• Mohan B, Gupta V, Ralhan S, et al. Role of extracorporeal membrane oxygenation in aluminum phosphide poisoning-induced reversible myocardial dysfunction: a novel therapeutic modality. J Emerg Med. 2015;49(5):651–656.
   PubMed Web of Science ®Google Scholar
• Lannemyr L, Knudsen K. Severe overdose of quetiapine treated successfully with extracorporeal life support. Clin Toxicol. 2012;50(4):258–261.
   Web of Science ®Google Scholar
• Auzinger GM, Scheinkestel CD. Successful extracorporeal life support in a case of severe flecainide intoxication. Crit Care Med. 2001;29(4):887–890.
   PubMed Web of Science ®Google Scholar
• Escajeda JT, Katz KD, Rittenberger JC. Successful treatment of metoprolol-induced cardiac arrest with high-dose insulin, lipid emulsion, and ECMO. Am J Emerg Med. 2015;33(8):1111.e1–1111.e4.
   Web of Science ®Google Scholar
• Maskell KF, Ferguson NM, Bain J, et al. Survival after cardiac arrest: ECMO rescue therapy after amlodipine and metoprolol overdose. Cardiovasc Toxicol. 2017;17(2):223–225.
   PubMed Web of Science ®Google Scholar
• Ghanim D, Adler Z, Qarawani D, et al. Takotsubo cardiomyopathy caused by epinephrine-treated bee sting anaphylaxis: a case report. J Med Case Rep. 2015;9:247.
   PubMedGoogle Scholar
• Williams JM, Hollingshed MJ, Vasilakis A, et al. Extracorporeal circulation in the management of severe tricyclic antidepressant overdose. Am J Emerg Med. 1994;12(4):456–458.
   PubMed Web of Science ®Google Scholar
• Rygnestad T, Moen S, Wahba A, et al. Severe poisoning with sotalol and verapamil. Recovery after 4 h of normothermic CPR followed by extra corporeal heart lung assist. Acta Anaesthesiol Scand. 2005;49(9):1378–1380.
   PubMed Web of Science ®Google Scholar
• Soumagne N, Chauvet S, Chatellier D, et al. Treatment of yew leaf intoxication with extracorporeal circulation. Am J Emerg Med. 2011;29(3):354.e5–354.e6.
   Web of Science ®Google Scholar
• Persad EA, Raman L, Thompson MT, et al. The use of extracorporeal life support in adolescent amlodipine overdose. Indian J Crit Care Med. 2012;16(4):204–206.
   PubMedGoogle Scholar
• Baran DA, Stelling K, McQueen D, et al. Pediatric veno-veno extracorporeal membrane oxygenation rescue from carbon monoxide poisoning. Pediatr Emerg Care. 2020;36(10):e592–e594.
   PubMed Web of Science ®Google Scholar
• Wang D, Zhang G, Zhang W, et al. Successful extracorporeal membrane oxygenation support for severe acute diquat and glyphosate poisoning: a case report. Medicine. 2019;98(6):e14414.
   PubMed Web of Science ®Google Scholar
• Sato H, Kyan R, Uemura S, et al. Usefulness of venoarterial extracorporeal membranous oxygenation for fatal cibenzoline succinate poisoning. Acute Med Surg. 2020;7(1):e507.
   PubMed Web of Science ®Google Scholar
• Schroeder I, Zoller M, Angstwurm M, et al. Venlafaxine intoxication with development of takotsubo cardiomyopathy: successful use of extracorporeal life support, intravenous lipid emulsion and CytoSorb®. Int J Artif Organs. 2017;40(7):358–360.
   PubMed Web of Science ®Google Scholar
• Koschny R, Lutz M, Seckinger J, et al. Extracorporeal life support and plasmapheresis in a case of severe polyintoxication. J Emerg Med. 2014;47(5):527–531.
   PubMed Web of Science ®Google Scholar
• Ramanathan K, Mohanty B, Tang S, et al. Extracorporeal therapy for amlodipine poisoning. J Artif Organs. 2020;23(2):183–186.
   PubMed Web of Science ®Google Scholar
• Farag M, Badowski D, Koschny R, et al. Extracorporeal life support and digoxin-specific Fab fragments for successful management of Taxus baccata intoxication with low output and ventricular arrhythmia. Am J Emerg Med. 2017;35(12):1987.e3–1987.e7.
   PubMed Web of Science ®Google Scholar
• Wu IL, Yu J-H, Lin C-C, et al. Fatal cardiac glycoside poisoning due to mistaking foxglove for comfrey. Clin Toxicol. 2017;55(7):670–673.
   PubMed Web of Science ®Google Scholar
• Sin JH, Tom A, Toyoda A, et al. High-dose intravenous lipid emulsion affecting successful initiation of continuous venovenous hemofiltration and extracorporeal membrane oxygenation. Clin Toxicol. 2018;56(2):149–150.
   Web of Science ®Google Scholar
• Behringer W, Sterz F, Domanovits H, et al. Percutaneous cardiopulmonary bypass for therapy resistant cardiac arrest from digoxin overdose. Resuscitation. 1998;37(1):47–50.
   PubMed Web of Science ®Google Scholar
• Vahdatpour C, Collins D, Goldberg S. Cardiogenic shock. J Am Heart Assoc. 2019;8(8):e011991.
   PubMed Web of Science ®Google Scholar
• van Diepen S, Katz JN, Albert NM, et al. Contemporary management of cardiogenic shock: a scientific statement from the American Heart Association. Circulation. 2017;136(16):e232–e268.
   PubMed Web of Science ®Google Scholar
• Richardson ASC, Tonna JE, Nanjayya V, et al. Extracorporeal cardiopulmonary resuscitation in adults. Interim guideline consensus statement from the extracorporeal life support organization. ASAIO J. 2021;67(3):221–228.
   PubMed Web of Science ®Google Scholar
• Shanmugasundaram M, Lotun K. Refractory out of hospital cardiac arrest. Curr Cardiol Rev. 2018;14(2):109–114.
   PubMed Web of Science ®Google Scholar
• Peek GJ, Clemens F, Elbourne D, et al. CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure. BMC Health Serv Res. 2006;6(1):163.
   PubMed Web of Science ®Google Scholar
• Combes A, Hajage D, Capellier G, et al. Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. N Engl J Med. 2018;378(21):1965–1975.
   PubMed Web of Science ®Google Scholar
• The ADTF. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307(23):2526–2533.
   PubMed Web of Science ®Google Scholar
• Abbasi A, Devers C, Muratore CS, et al. Examining the role of extracorporeal membrane oxygenation in patients following suspected or confirmed suicide attempts: a case series. J Crit Care. 2018;44:445–449.
   PubMed Web of Science ®Google Scholar
• St-Onge M, Fan E, Megarbane B, et al. Venoarterial extracorporeal membrane oxygenation for patients in shock or cardiac arrest secondary to cardiotoxicant poisoning: a cost-effectiveness analysis. J Crit Care. 2015;30(2):437.e7–437.e14.
   Web of Science ®Google Scholar
• Tang X, Sun B, He H, et al. Successful extracorporeal membrane oxygenation therapy as a bridge to sequential bilateral lung transplantation for a patient after severe paraquat poisoning. Clin Toxicol. 2015;53(9):908–913.
   PubMed Web of Science ®Google Scholar
• Teerapuncharoen K, Sharma NS, Barker AB, et al. Successful treatment of severe carbon monoxide poisoning and refractory shock using extracorporeal membrane oxygenation. Respir Care. 2015;60(9):e155–e160.
   PubMed Web of Science ®Google Scholar
• McCunn M, Reynolds HN, Cottingham CA, et al. Extracorporeal support in an adult with severe carbon monoxide poisoning and shock following smoke inhalation: a case report. Perfusion. 2000;15(2):169–173.
   PubMed Web of Science ®Google Scholar
• Lewis J, Zarate M, Tran S, et al. The recommendation and use of extracorporeal membrane oxygenation (ECMO) in cases reported to the California Poison Control System. J Med Toxicol. 2019;15(3):169–177.
   PubMed Web of Science ®Google Scholar
• Jacquot A, Lepage X, Merckle L, et al. Protocol for a multicentre randomised controlled trial evaluating the effects of moderate hypothermia versus normothermia on mortality in patients with refractory cardiogenic shock rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) (HYPO-ECMO study). BMJ Open. 2019;9(10):e031697.
   PubMed Web of Science ®Google Scholar
• Turner-Lawrence DE, Kerns Ii W. Intravenous fat emulsion: a potential novel antidote. J Med Toxicol. 2008;4(2):109–114.
   PubMedGoogle Scholar
• Buck ML, Ksenich RA, Wooldridge P. Effect of infusing fat emulsion into extracorporeal membrane oxygenation circuits. Pharmacotherapy. 1997;17(6):1292–1295.
   PubMed Web of Science ®Google Scholar
• Lee HMD, Archer JRH, Dargan PI, et al. What are the adverse effects associated with the combined use of intravenous lipid emulsion and extracorporeal membrane oxygenation in the poisoned patient? Clin Toxicol. 2015;53(3):145–150.
   Web of Science ®Google Scholar
• Johnson-Arbor K, Salinger L, Luczycki S. Prolonged laboratory interference after administration of intravenous lipid emulsion therapy. J Med Toxicol. 2015;11(2):223–226.
   PubMed Web of Science ®Google Scholar
• Knecht M, LaRochelle J, Barkemeyer B, et al. Cardiac collapse secondary to phenytoin toxicity in a neonate treated with extracorporeal membrane oxygenation support (ECMO). J Med Toxicol. 2020;16(2):230–235.
   PubMed Web of Science ®Google Scholar
• Frazee EN, Lee SJ, Kalimullah EA, et al. Circulatory support with venoarterial ECMO unsuccessful in aiding endogenous diltiazem clearance after overdose. Case Rep Crit Care. 2014;2014:969578.
   PubMedGoogle Scholar
• Kato Y, Kuriyama A, Hata R, et al. Extracorporeal membrane oxygenation for hypokalemia and refractory ventricular fibrillation associated with caffeine intoxication. J Emerg Med. 2020;58(1):59–62.
   Web of Science ®Google Scholar
• Brumfield E, Bernard KRL, Kabrhel C. Life-threatening flecainide overdose treated with intralipid and extracorporeal membrane oxygenation. Am J Emerg Med. 2015;33(12):1840.e3–1840.e5.
   Web of Science ®Google Scholar
• Bacon B, Silverton N, Katz M, et al. Local anesthetic systemic toxicity induced cardiac arrest after topicalization for transesophageal echocardiography and subsequent treatment with extracorporeal cardiopulmonary resuscitation. J Cardiothorac Vasc Anesth. 2019;33(1):162–165.
   PubMed Web of Science ®Google Scholar
• Fadhlillah F, Patil S. Pharmacological and mechanical management of calcium channel blocker toxicity. BMJ Case Reports. 2018;2018:bcr2018225324.
   Google Scholar
• Hantson P, Wuidart C, Haufroid V. Severe and prolonged flecainide intoxication treated by extracorporeal life support: possible role of cytochrome P450 2D6 polymorphism? Clin Toxicol. 2019;57(7):672–673.
   PubMed Web of Science ®Google Scholar
• Reynolds JC, Judge BS. Successful treatment of flecainide-induced cardiac arrest with extracorporeal membrane oxygenation in the ED. Am J Emerg Med. 2015;33(10):1542.e1–1542.e2.
   Web of Science ®Google Scholar
• Heise CW, Skolnik AB, Raschke RA, et al. Two cases of refractory cardiogenic shock secondary to bupropion successfully treated with veno-arterial extracorporeal membrane oxygenation. J Med Toxicol. 2016;12(3):301–304.
   PubMed Web of Science ®Google Scholar
• Haughey R, Vernick W, Gutsche J, et al. Use of veno-venous extracorporeal membrane oxygenation to treat severe combined calcium channel blocker and angiotensin converting enzyme inhibitor overdose. Perfusion. 2019;34(2):167–169.
   PubMed Web of Science ®Google Scholar
• Hong S-B, Kim HJ, Huh JW, et al. A cluster of lung injury associated with home humidifier use: clinical, radiological and pathological description of a new syndrome. Thorax. 2014;69(8):694–702.
   PubMed Web of Science ®Google Scholar
• Jhang WK, Park SJ, Lee E, et al. The first successful heart-lung transplant in a Korean child with humidifier disinfectant-associated interstitial lung disease. J Korean Med Sci. 2016;31(5):817–821.
   PubMed Web of Science ®Google Scholar