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Letters in Response

Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series

, ORCID Icon & ORCID Icon
Page 666 | Received 15 Nov 2021, Accepted 18 Nov 2021, Published online: 23 Dec 2021

References

  • Link SL, Rampon G, Osmon S, et al. Fomepizole as an adjunctive treatment in severe acetaminophen ingestions: a case series. Clin Toxicol. 2021. DOI: https://doi.org/10.1080/15563650.2021.1996591
  • Akakpo JY, Ramachandran A, Duan L, et al. Delayed treatment with 4-methylpyrazole protects against acetaminophen hepatotoxicity in mice by inhibition of c-Jun n-Terminal kinase. Toxicol Sci. 2019;170(1):57–68.
  • Rampon G, Wartman H, Osmon S, et al. Use of fomepizole as an adjunct in the treatment of acetaminophen overdose: a case series. Toxicol Commun. 2020;4(1):1–4.
  • Smilkstein MJ, Knapp GL, Kulig KW, et al. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985). N Engl J Med. 1988;319(24):1557–1562. Dec 15 PMID: 3059186.
  • Cumberland Pharmaceuticals Inc. Acetadote [package insert]. U.S. Food and Drug Administration website. [Revised 30 October 2019; Accessed 11 November 2021] https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process
  • Sivilotti MLA, Green TJ, Langmann C, et al. Multiplying the serum aminotransferase by the acetaminophen concentration to predict toxicity following overdose. Clin Toxicol. 2010;48(8):793–799.

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