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Clinical Research

Suspected suicides and nonfatal suicide attempts involving antidepressants reported to United States poison control centers, 2000–2020

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Pages 818-826 | Received 24 Nov 2021, Accepted 07 Feb 2022, Published online: 21 Feb 2022

References

  • Mojtabai R, Olfson M. National trends in long-term use of antidepressant medications: Results from the U.S. National health and nutrition examination survey. J Clin Psychiatry. 2014;75(02):169–177.
  • Pratt LA, Brody DJ, Gu Q. Antidepressant use among persons aged 12 and over: United States, 2011-2014. NCHS Data Brief. 2017;283:1–8.
  • Brody DJ, Gu Q. Antidepressant use among adults: United States, 2015-2018. Hyattsville, MD: National Center for Health Statistics; 2020. (NCHS Data Brief; no 377). Available from: https://www.cdc.gov/nchs/data/databriefs/db377-H.pdf.
  • Martin CB, Hales CM, Gu Q, et al. Prescription drug use in the United States, 2015-2016. NCHS Data Brief. 2019;334:1–8.
  • Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: Results from the 2019 national survey on drug use and health. Rockville, MD: Center for behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration; 2020. (HHS Publication; No. PEP20-07-01-001, NSDUH Series; H-55). https://www.samhsa.gov/data/sites/default/files/reports/rpt29393/2019NSDUHFFRPDFWHTML/2019NSDUHFFR090120.htm.
  • Cipriani A, Furukawa TA, Salanti G, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet. 2009;373(9665):746–758.
  • Cipriani A, Furukawa TA, Salanti G, et al. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018; 391(10128):1357–1366.
  • Web-based Injury Statistics Query and Reporting System (WISQARS). Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control 2020. [Accessed Aug 26th, 2021]. Available from: https://www.cdc.gov/injury/wisqars/index.html.
  • Spiller HA, Ackerman JP, Smith GA, et al. Suicide attempts by self-poisoning in the United States among 10-25 year olds from 2000 to 2018: substances used, temporal changes and demographics. Clin Toxicol. 2020; 58(7):676–687.
  • Cash SJ, Bridge JA. Epidemiology of youth suicide and suicidal behavior. Curr Opin Pediatr. 2009; 21(5):613–619.
  • Stone DM, Simon TR, Fowler KA, et al. Vital signs: Trends in state suicide rates - United States, 1999-2016 and circumstances contributing to suicide - 27 states, 2015. MMWR Morb Mortal Wkly Rep. 2018; 67(22):617–624.
  • Sullivan EM, Annest JL, Simon TR, Centers for Disease Control and Prevention (CDC), et al. Suicide trends among persons aged 10-24 years—United States, 1994-2012. MMWR Morb Mortal Wkly Rep. 2015;64(8):201–205.
  • Geulayov G, Kapur N, Turnbull P, et al. Epidemiology and trends in non-fatal self-harm in three centres in England, 2000-2012: Findings from the multicentre study of self-harm in England. BMJ Open. 2016;6(4):e010538.
  • Tadros G, Salib E. Age and methods of fatal self harm (FSH). is there a link? Int J Geriat Psychiatry. 2000; 15(9):848–852.
  • D'Mello DA, Finkbeiner DS, Kocher KN. The cost of antidepressant overdose. Gen Hosp Psychiatry. 1995;17(6):454–455.
  • Power BM, Hackett LP, Dusci LJ, et al. Antidepressant toxicity and the need for identification and concentration monitoring in overdose. Clin Pharmacokinet. 1995;29(3):154–171.
  • Buckley NA, Whyte IM, Dawson AH, et al. Correlations between prescriptions and drugs taken in self-poisoning. Implications for prescribers and drug regulation. Med J Aust. 1995; 162(4):194–197.
  • Chafe R, Aslanova R, Hamud O, et al. Hospitalizations due to self-poisoning at a canadian paediatric hospital. Paediatr Child Health. 2018; 23(2):101–105.
  • Gummin DD, Mowry JB, Beuhler MC, et al. 2019 Annual report of the american association of poison control centers' national poison data system (NPDS): 37th annual report. Clin Toxicol. 2020; 58(12):1360–1541.
  • American Association of Poison Control Centers. NPDS coding user's manual. National Poison Data System. [Accessed Aug 26th, 2021]. Available from: https://www.aapcc.org/national-poison-data-system.
  • Curtin SC, Warner M, Hedegaard H. Increase in suicide in the United States, 1999-2014. NCHS Data Brief. 2016 Apr(241):1-8.
  • Shain B, Braverman PK, Adelman WP, et al.; COMMITTEE ON ADOLESCENCE. Suicide and suicide attempts in adolescents. Pediatrics. 2016;138(1):e20161420.
  • Spiller HA, Ackerman JP, Spiller NE, et al. Sex- and age-specific increases in suicide attempts by self-poisoning in the United States among youth and young adults from 2000 to 2018. J Pediatr. 2019; 210:201–208.
  • Ivey-Stephenson AZ, Demissie Z, Crosby AE, et al. Suicidal ideation and behaviors among high school students - Youth risk behavior survey, United States, 2019. MMWR Suppl. 2020; 69(1):47–55.
  • McGirr A, Renaud J, Bureau A, et al. Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide. Psychol Med. 2008;38(3):407–417.
  • Casey BJ, Jones RM, Levita L, et al. The storm and stress of adolescence: Insights from human imaging and mouse genetics. Dev Psychobiol. 2010;52(3):225–235.
  • Centers for Disease Control and Prevention. Suicide prevention. CDC.gov [internet]. Atlanta, GA: CDC; [updated 2021 May 13]. [Accessed Aug 26th, 2021. Available from: https://www.cdc.gov/suicide/factors/index.html.
  • Brent DA. Antidepressants and suicidality. Psychiatr Clin North Am. 2016;39(3):503–512.
  • Phillips JA, Nugent CN. Antidepressant use and method of suicide in the United States: Variation by age and sex, 1998-2007. Arch Suicide Res. 2013;17(4):360–372.
  • Read J, Williams J. Adverse effects of antidepressants reported by a large international cohort: Emotional blunting, suicidality, and withdrawal effects. Curr Drug Saf. 2018;13(3):176–186.
  • McKenzie MS, McFarland BH. Trends in antidepressant overdoses. Pharmacoepidemiol Drug Saf. 2007; 16(5):513–523.
  • Isacsson G, Rich CL. Antidepressant drugs and the risk of suicide in children and adolescents. Paediatr Drugs. 2014;16(2):115–122.
  • Cheung K, Aarts N, Noordam R, et al. Antidepressant use and the risk of suicide: a population-based cohort study. J Affect Disord. 2015; 174:479–484.
  • Amendola S, Plöderl M, Hengartner MP. Did the introduction and increased prescribing of antidepressants lead to changes in long-term trends of suicide rates? Eur J Public Health. 2021; 31(2):291–297.
  • Centers for Disease Control and Prevention. Health, United States, 2019. Hyattsville, MD: National Center for Health Statistics; 2021. [Accessed Aug 26th, 2021]. Available from: https://www.cdc.gov/nchs/data/hus/hus19-508.pdf.
  • Beckman L, von Kobyletzki L, Svensson M. Economic costs of antidepressant use: a population-based study in Sweden. J Ment Health Policy Econ. 2019; 22(4):125–130.
  • Bergen H, Murphy E, Cooper J, et al. A comparative study of non-fatal self-poisoning with antidepressants relative to prescribing in three centres in England. J Affect Disord. 2010; 123(1-3):95–101.
  • Doak MW, Nixon AC, Lupton DJ, et al. Self-poisoning in older adults: Patterns of drug ingestion and clinical outcomes. Age and Ageing. 2009;38(4):407–411.
  • Spiller HA, Appana S, Brock GN. Epidemiological trends of suicide and attempted suicide by poisoning in the US: 2000-2008. Legal Med. 2010;12(4):177–183.
  • Luo Y, Kataoka Y, Ostinelli EG, et al. National prescription patterns of antidepressants in the treatment of adults with major depression in the US between 1996 and 2015: a population representative survey based analysis. Front Psychiatry. 2020;11:35.
  • Hawton K, Bergen H, Simkin S, et al. Toxicity of antidepressants: Rates of suicide relative to prescribing and non-fatal overdose. Br J Psychiatry. 2010;196(5):354–358.
  • Land ME, Wetzel M, Geller RJ, et al. Adult opioid poisonings by drug, intent, and resource use from the United States national poison data system from 2005-2018. [ePub before print 2020 july 17]. Clin Toxicol. 2020;59(2):142–151.
  • Wang A, Law R, Lyons R, et al. Assessing the public health impact of using poison center data for public health surveillance. Clin Toxicol. 2018; 56(7):646–652.

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