Veratrum parviflorum poisoning: identification of steroidal alkaloids in patient blood and breast milk

References

• Zomlefer WB, Whitten WM, Williams NH, et al. An overview of Veratrum sl (Liliales: Melanthiaceae) and an infrageneric phylogeny based on ITS sequence data. Syst Bot. 2003;28(2):250–269.
   Web of Science ®Google Scholar
• Chandler CM, McDougal OM. Medicinal history of North American veratrum. Phytochem Rev. 2014;13(3):671–694.
   PubMed Web of Science ®Google Scholar
• Dirks ML, Seale JT, Collins JM, et al. Review: Veratrum californicum alkaloids. Molecules. 2021;26(19):5934.
   PubMed Web of Science ®Google Scholar
• Dey P, Kundu A, Chakraborty HJ, et al. Therapeutic value of steroidal alkaloids in cancer: current trends and future perspectives. Int J Cancer. 2019;145(7):1731–1744.
   PubMed Web of Science ®Google Scholar
• Schep LJ, Schmierer DM, Fountain JS. Veratrum poisoning. Toxicol Rev. 2006;25(2):73–78.
   PubMedGoogle Scholar
• von Bezold A. Über die physiologischen wirkungen des essigsauren veratrins. Untersuchungen aus dem physiologischen Laboratorium in Wurzburg. 1867;1:75–156.
   Google Scholar
• Jarisch A, Richter H. Die kreislaufwirkung des veratrins. Archiv f experiment Pathol Pharmakol. 1939;193(2–4):347–354.
   Google Scholar
• Schaefer H. Elektrophysiologie der Herznerven. Rev Physiol Biochem Pharmacol. 1950;46(1):71–125.
   Google Scholar
• Armstrong CG. Skookum root. EBL. 2018;9(2):197–205.
   Google Scholar
• Osgood C. ART. II. Observations on the medicinal properties of the Veratrum viride. Am J Med Sci. 1924;1835:296.
   Google Scholar
• Anwar M, Turner M, Farrell N, et al. Hikers poisoned: Veratrum steroidal alkaloid toxicity following ingestion of foraged Veratrum parviflorum. Clin Toxicol (Phila). 2018;56(9):841–845.
   PubMed Web of Science ®Google Scholar
• Jaffe AM, Gephardt D, Courtemanche L. Poisoning due to ingestion of Veratrum viride (false hellebore). J Emerg Med. 1990;8(2):161–167.
   PubMedGoogle Scholar
• Prince L, Stork C. Prolonged cardiotoxicity from poison lilly (Veratrum viride). Vet Hum Toxicol. 2000;42(5):282–285.
   PubMedGoogle Scholar
• Zagler B, Zelger A, Salvatore C, et al. Dietary poisoning with Veratrum album–a report of two cases. Wien Klin Wochenschr. 2005;117(3):106–108.
   PubMed Web of Science ®Google Scholar
• Forrester JD, Price JH, Holstege CP. Intoxication with a ramp (Allium tricocca) mimicker. Wilderness Environ Med. 2010;21(1):61–63.
   PubMed Web of Science ®Google Scholar
• Gilotta I, Brvar M. Accidental poisoning with Veratrum album mistaken for wild garlic (Allium ursinum). Clin Toxicol (Phila). 2010;48(9):949–952.
   PubMed Web of Science ®Google Scholar
• Melnik EV, Belova MV, Potskhveriya MM, et al. Veratrum alkaloid determination in four cases of veratrum aqua poisonings. J Anal Toxicol. 2022;46(1):42–47.
   Web of Science ®Google Scholar
• Festa M, Andreetto B, Ballaris M, et al. A case of veratrum poisoning. Minerva Anestesiol. 1996;62(5):195–196.
   PubMedGoogle Scholar
• Grobosch T, Binscheck T, Martens F, et al. Accidental intoxication with Veratrum album. J Anal Toxicol. 2008;32(9):768–773.
   PubMed Web of Science ®Google Scholar
• Wildflower.org [Internet]. Texas: Lady Bird Johnson Wildflower Center; [cited 2022 Mar 22]. Available from: https://www.wildflower.org/gallery/result.php?id_image=66638.
   Google Scholar
• Liao W-J, Yuan Y-M, Zhang D-Y. Biogeography and evolution of flower color in Veratrum (Melanthiaceae) through inference of a phylogeny based on multiple DNA markers. Plant Syst Evol. 2007;267(1–4):177–190.
   Web of Science ®Google Scholar
• Watson S. Contributions to American Botany: revision of the North American Liliaceae; descriptions of some new species of North American plants. Proc Am Acad Arts Sci. 1878;14:213–303.
   Google Scholar
• Turner MW, Rossi M, Campfield V, et al. Steroidal alkaloid variation in Veratrum californicum as determined by modern methods of analytical analysis. Fitoterapia. 2019;137:104281.
   PubMed Web of Science ®Google Scholar
• Dumlu FA, Aydin T, Odabasoglu F, et al. Anti-inflammatory and antioxidant properties of jervine, a sterodial alkaloid from rhizomes of Veratrum album. Phytomedicine. 2019;55:191–199.
   PubMed Web of Science ®Google Scholar
• El Sayed KA, McChesney JD, Halim AF, et al. A study of alkaloids in Veratrum viride aiton. Int J Pharmacogn. 1996;34(3):161–173.
   Google Scholar
• Keeler RF, Binns W. Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources. Teratology. 1968;1(1):5–10.
   PubMedGoogle Scholar
• Zheng B, Wang C, Song W, et al. Pharmacokinetics and enterohepatic circulation of jervine, an antitumor steroidal alkaloid from Veratrum nigrum in rats. J Pharm Anal. 2019;9(5):367–372.
   PubMed Web of Science ®Google Scholar
• Keeler RF. Teratogenic compounds of Veratrum californicum (durand)—IV. First isolation of veratramine and alkaloid Q and a reliable method for isolation of cyclopamine. Phytochemistry. 1968;7(2):303–306.
   Web of Science ®Google Scholar
• Wang L, Li W, Liu Y. Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes of Veratrum nigrum L. in spontaneously hypertensive rats. Pharmazie. 2008;63(8):606–610.
   PubMed Web of Science ®Google Scholar
• Cong Y, Guo J, Tang Z, et al. Metabolism study of veratramine associated with neurotoxicity by using HPLC–MSn. J Chromatogr Sci. 2015;53(7):1092–1099.
   PubMed Web of Science ®Google Scholar
• Fan Q, Gu D, He M, et al. Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling. Chin J Cancer. 2011;30(7):472–481.
   PubMedGoogle Scholar
• Clewell RA, Gearhart JM. Pharmacokinetics of toxic chemicals in breast milk: use of PBPK models to predict infant exposure. Environ Health Perspect. 2002;110(6):A333–A337.
   PubMed Web of Science ®Google Scholar
• Ward E, Yang N, Muhlhausler BS, et al. Acute changes to breast milk composition following consumption of high-fat and high-sugar meals. Matern Child Nutr. 2021;17(3):e13168.
   PubMed Web of Science ®Google Scholar
• Bechtel LK, Lawrence DT, Haverstick D, et al. Ingestion of false hellebore plants can cross-react with a digoxin clinical chemistry assay. Clin Toxicol (Phila). 2010;48(5):435–442.
   PubMed Web of Science ®Google Scholar
• Fink SL, Robey TE, Tarabar AF, Hodsdon ME. Rapid detection of convallatoxin using five digoxin immunoassays. Clin Toxicol. 2014;52(7):659–663.
   Google Scholar