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Clinical Research

Implementation of a pharmacist toxicology service on treatment of paracetamol (acetaminophen) overdose

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Pages 162-165 | Received 19 Jul 2022, Accepted 27 Dec 2022, Published online: 09 Mar 2023

References

  • Gummin D, Mowry J, Beuhler M, et al. 2020 Annual report of the American association of poison control centers’ National Poison Data System (NPDS): 38th annual report. Clin Toxicol (Phila). 2021;59(12):1282–1501.
  • Hendrickson RG, McKeown NJ, Nelson LS, et al. Acetaminophen. In: Nelson LS, Howland M, Lewin NA, Smith SW, Goldfrank LR, Hoffman RS, editors. Goldfrank’s toxicologic emergencies. 11 ed. New York (NY): McGraw Hill; 2019. August 8, 2021.
  • Cumberland Pharmaceuticals. 2006. Acetadote. Nashville, TN [Package Insert]
  • Agrawal S, Khazaeni B. Acetaminophen toxicity. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022.
  • American College of Medical Toxicology. ACMT position statement: duration of intravenous acetylcysteine therapy following acetaminophen overdose. J Med Toxicol. 2017;13(1):126–127.
  • Tsai C, Chang W, Weng T, et al. A patient-tailored N-acetylcysteine protocol for acute acetaminophen intoxication. Clin Ther. 2005;27(3):336–341.
  • Woo O, Mueller P, Olson K, et al. Shorter duration of oral N-Acetylcysteine therapy for acute acetaminophen overdose. Ann Emerg Med. 2000;35(4):363–368.
  • Lucyk S, Yarema M, Sivilotti M, et al. Outcomes of patients with premature discontinuation of the 21-h intravenous N-Acetylcysteine protocol after acute acetaminophen overdose. J Emerg Med. 2016;50(4):629–637.
  • O’Grady J, Alexander G, Hayllar KM, et al. Early indicators of prognosis in fulminant hepatic failure. Gastroenterology. 1989;97(2):439–445.
  • Schmidt L, Dalhoff K. Serum phosphate is an early predictor of outcome in severe acetaminophen-induced hepatotoxicity. Hepatology. 2002;36(3):659–665.
  • Bernal W, Donaldson N, Wyncoll D, et al. Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study. Lancet. 2002;359(9306):558–563.
  • Charpiat B, Bedouch P, Rose F, et al. Overdosed paracetamol (acetaminophen) prescriptions and subsequent pharmacist interventions in french hospitals. Ann Pharm Fr. 2013;71(6):410–417.
  • Ghosh A, Berger I, Remien C, et al. The role of alcohol consumption on acetaminophen induced liver injury: implications from a mathematical model. J Theor Biol. 2021;519:110559.

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