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Clinical Toxicology Volume 61, 2023 - Issue 8
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Editorial

Lipid emulsion in the poisoned patient – a few answers, but more questions remain

Michael E. MullinsEditor Division of Medical Toxicology, Department of Emergency Medicine, WA University School of Medicine, St Louis, MO, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8605-0217View further author information
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Pages 565-566 | Received 23 Aug 2023, Accepted 24 Aug 2023, Published online: 10 Oct 2023

References

  • Levine M, Brent J, Wiegand T, et al. Lipid emulsion therapy during management of the critically-ill poisoned patient: a prospective cohort study. Clin Toxicol. 2023;61(8):584–590. doi:10.1080/15563650.2023.2248372.
  • Fettiplace MR, Weinberg G. Lipid emulsion for xenobiotic overdose: PRO. Br J Clin Pharmacol. 2023;89(6):1708–1718. doi:10.1111/bcp.15620.
  • Gosselin S, Bania TC. Lipid emulsion. In: Nelson LS, Howland M, Lewin NA, Smith SW, Goldfrank LR, Hoffman RS, editors. Goldfrank’s toxicologic emergencies. 11th ed. New York (NY): McGraw Hill; 2019.
  • Appendix: calculated log P, log D, and pKa. In: beale JM, Block JH, editors. Wilson and Gisvold’s textbook of organic medicinal and pharmaceutical chemistry. 12th ed. Philadelphia (PA): Lippincott, Williams & Wilkins; 2011.
  • Wax PM, Kleinschmidt KC, Brent J; ACMT ToxIC Case Registry Investigators. The toxicology investigators consortium (ToxIC) registry. J Med Toxicol. 2011;7(4):259–265. doi:10.1007/s13181-011-0177-z.
  • Levine M, Skolnik AB, Ruha AM, et al. Complications following antidotal use of intravenous lipid emulsion therapy. J Med Toxicol. 2014;10(1):10–14. doi:10.1007/s13181-013-0356-1.
  • Grunbaum AM, Gilfix BM, Hoffman RS, et al. Review of the effect of intravenous lipid emulsion on laboratory analyses. Clin Toxicol (Phila). 2016;54(2):92–102. doi:10.3109/15563650.2015.1115515.
  • Hayes BD, Gosselin S, Calello DP, et al. Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration. Clin Toxicol (Phila). 2016;54(5):365–404. doi:10.3109/15563650.2016.1151528.
  • Jovic-Stosik J, Putic V, Djordjevic S, et al. Lipid emulsion in treatment of cardiovascular collapse in acute poisoning [abstract]. Clin Toxicol. 2013;51:288–289.
  • Agarwala R, Ahmed SZ, Wiegand TJ. Prolonged use of intravenous lipid emulsion in a severe tricyclic antidepressant overdose. J Med Toxicol. 2014;10(2):210–214. doi:10.1007/s13181-013-0353-4.
  • Smolinske S, Hoffman RS, Villeneuve E, et al. Utilization of lipid emulsion therapy in fatal overdose cases: an observational study. Clin Toxicol (Phila). 2019;57(3):197–202. doi:10.1080/15563650.2018.1504954.
  • Clemons J, Jandu A, Stein B, et al. Efficacy of lipid emulsion therapy in treating cardiotoxicity from diphenhydramine ingestion: a review and analysis of case reports. Clin Toxicol (Phila). 2022;60(5):550–558. doi:10.1080/15563650.2022.2038187.
  • Gosselin S, Hoegberg LCG, Hoffman RS, et al. Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning. Clin Toxicol (Phila). 2016;54(10):899–923. doi:10.1080/15563650.2016.1214275.

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