239
Views
24
CrossRef citations to date
0
Altmetric
Case Report

Lamotrigine-induced seizures in a child: Case report and literature review

, M.D., , Pharm.D., , M.D. & , M.D.
Pages 169-172 | Received 15 Mar 2005, Accepted 18 Oct 2005, Published online: 07 Oct 2008

References

  • Wong IC, Mawer GE, Sander JW. Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom. Epilepsia 2001; 42: 237–244
  • Jones JE, Hermann BP, Barry JJ, Gilliam FG, Kanner AM, Meador KJ. Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsy. Epilepsy and Behavior 2003; 4: S31–S38
  • Brent DA, Kolko DJ. Suicidality in affectively disordered adolescent inpatients. J Am Acad Chld Adolesc Psychiatry 1990; 29: 587–593
  • Briassoulis G, Kalabalikis P, Tamiolaki M, Hatzis T. Lamotrigine childhood overdose. Pediatric Neurology 1998; 19: 239–242
  • Buckley NA, Whyte IM, Dawson AH. Self-poisoning with lamotrigine. Lancet 1993; 33: 557–559
  • O'Donnell J, Batemean DN. Lamotrigine overdose in an adult. Clinical Toxicology 2000; 38: 659–660
  • Sbei M, Campellone JV. Stupor from lamotrigine toxicity. Epilepsia 2001; 42: 1082–1083
  • Richens A. Safety of lamotrigine. Epilepsia 1994; 35: S37–S40
  • Schmidt D, Kramer G. The new anticonvulsant drugs. Drug Safety 1994; 11: 422–431
  • Fayad M, Choueiri R, Mikati M. Potential hepatotoxicity of lamotrigine. Pediatric Neurology 2000; 22: 49–52
  • Overstreet K, Costanza C, Behling C, et al. Fatal progressive hepatic necrosis associated with lamotrigine treatment. Digestive Diseases and Sciences 2002; 47: 1921–1925
  • Yuen AWC, Bihari DJ. Multiorgan failure and disseminated intravascular coagulation in severe convulsive seizures. Lancet 1992; 341: 618
  • Messenheimer JA, Giorgi L, Risner ME. The tolerability of lamotrigine in children. Drug Safety 2000; 22: 303–312
  • Brodie MJ. Lamotrigine. Lancet 1992; 339: 1397–1400
  • Poisoning and drug overdose 4th, KR Olson. McGraw Hill, San Francisco 2004
  • Fillastre JP, Taburet AM, Fialaire A. Pharmacokinetics of lamotrigine in patients with renal impairment: influence of haemodialysis. Drugs Exptl Clin Res 1993; 19: 25–32
  • Kilpatrick ES, Forrest G, Brodie MJ. Concentration-effect and concentration toxicity relations with lamotrigine: a prospective study. Epilepsia 1996; 37: 534–538
  • Stopforth J. Overdose with gabapentin and lamotrigine. S Afr Med J 1997; 87: 1388
  • Pricone MG, King CV, Drummer OH, Opeskin K, McIntyre IM. Postmortem investigation of lamotrigine concentrations. J Forensic Sci 2000; 45: 11–15
  • Lofton AL, Klein-Schwartz W. Evaluation of lamotrigine toxicity reported to poison centers. Ann Pharmacother 2004; 38: 1811–1815
  • Cronin NB, O'Reilly A, Duclohier H, Wallace BA. Effects of deglycosylation of sodium channels on their structure and function. Biochemistry 2005; 44: 441–449
  • Cronin NB, O'Reilly A, Duclohier H, Wallace BA. Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation. J Biol Chem 2003; 278: 10675–10682
  • Liu G, Yarov-Yarovy V, Nobbs M, Clare JJ, Scheuer T, Catterall WA. Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels. Neuropharmacology 2003; 44: 413–422

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.