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Research Article

Correlation of paired plasma and saliva paracetamol levels following deliberate self-poisoning with paracetamol (The Salivary Paracetamol In Toxicology [SPIT] study)

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Pages 534-538 | Received 07 May 2007, Accepted 05 Sep 2007, Published online: 20 Jan 2009

References

  • Lai MW, Klein-Schwartz W, Rodgers GC, et al. 2005 Annual Report of the American Association of Poison Control Centers' national poisoning and exposure database. Clin Toxicol (Phila) 2006; 44: 803–932
  • Rumack BH, Matthew H. Acetaminophen poisoning and toxicity. Pediatrics 1975; 55: 871–6
  • Kamali F, Fry JR, Bell GD. Salivary secretion of paracetamol in man. J Pharm Pharmacol 1987; 39: 150–2
  • Smith M, Whitehead E, O'sullivan G, Reynolds FA. Comparison of serum and saliva paracetamol concentrations. Br J Clin Pharmacol 1991; 31: 553–5
  • Sanaka M, Kuyama Y, Nishinakagawa S, Mineshita S. Use of salivary acetaminophen concentration to assess gastric emptying rate of liquids. J Gastroenterol 2000; 35: 429–33
  • Nakano M, Nakano N, Funada S, Iwasaka K. Correlation between salivary and plasma levels of acetaminophen. Jpn J Clin Pharmacol 1988; 19: 549–553
  • Glynn JP, Bastain W. Salivary excretion of paracetamol in man. J Pharm Pharmacol 1973; 25: 420–1
  • Adithan C, Thangam J. A comparative study of saliva and serum paracetamol levels using a simple spectrophotometric method. Br J Clin Pharmacol 1982; 14: 107–9
  • Hahn TW, Henneberg SW, Holm-knudsen RJ, et al. Pharmacokinetics of rectal paracetamol after repeated dosing in children. Br J Anaesth 2000; 85: 512–9
  • Hahn TW, Mogensen T, Lund C, Schouenborg L, Rasmussen M. High-dose rectal and oral acetaminophen in postoperative patients—serum and saliva concentrations. Acta Anaesthesiol Scand 2000; 44: 302–6
  • Al-Obaidy SS, Li Wan Po A, Mckiernan PJ, Glasgow JF, Millership J. Assay of paracetamol and its metabolites in urine, plasma and saliva of children with chronic liver disease. J Pharm Biomed Anal 1995; 13: 1033–9
  • Ludbrook J. Comparing methods of measurements. Clin Exp Pharmacol Physiol 1997; 24: 193–203
  • Panting R. Validation of Saliva-based Paracetamol assessment. University of Otago, Dunedin 2005
  • Daly FF, Little M, Murray L. A risk assessment based approach to the management of acute poisoning. Emerg Med J 2006; 23: 396–9
  • Paracetamol. Toxicology Handbook, L Murray, F Daly, M Little, M Cadogan. Elsevier, Sydney 2007
  • Hamlyn AN, Douglas AP, James O. The spectrum of paracetamol (acetaminophen) overdose: clinical and epidemiological studies. Postgrad Med J 1978; 54: 400–4
  • Gorodischer R, Burtin P, Hwang P, Levine M, Koren G. Saliva versus blood sampling for therapeutic drug monitoring in children: patient and parental preferences and an economic analysis. Ther Drug Monit 1994; 16: 437–43
  • Kamali F, Edwards C, Rawlins MD. The effect of pirenzepine on gastric emptying and salivary flow rate: constraints on the use of saliva paracetamol concentrations for the determination of paracetamol pharmacokinetics. Br J Clin Pharmacol 1992; 33: 309–12

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