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Research Article

Comparison of in vitro eye irritation potential by bovine corneal opacity and permeability (BCOP) assay to erythema scores in human eye sting test of surfactant-based formulations

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Pages 77-85 | Published online: 10 Oct 2008

References

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  • Shanahan RW, Ward CD. An animal model for estimating the relative sting potential of shampoos. J Soc Cosmetic Chem 1975; 26: 581–592
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  • Cooper KJ, Earl LK, Harbell JW, Raabe H. Prediction of ocular irritancy of prototype shampoo formulations by the isolated rabbit eye (IRE) test and bovine corneal opacity and permeability (BCOP) assay. Toxicol In Vitro 2001; 15: 95–103
  • Sina JF, Galer DM, Sussman RG, Gautheron PD, Sargent EV, Leong B, Shah PV, Curren RD, Miller K. A collaborative evaluation of seven alternatives to the Draize eye irritation test using pharmaceutical intermediates. Fundam Appl Toxicol 1995; 26: 20–31
  • Draize JH, Woodard G, Calvery HO. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther 1944; 82: 377–390

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