The possible effect of pentoxifylline on development and severity of retinopathy of prematurity

References

• Zin A, Gole GA. Retinopathy of prematurity-incidence today. Clin Perinatol 2013;40:185–200.
   PubMed Web of Science ®Google Scholar
• Blencowe H, Lawn JE, Vazquez T, et al. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res 2013;74(Suppl 1):35–49.
   PubMed Web of Science ®Google Scholar
• Bas AY, Demirel N, Koc E, et al. TR-ROP Study Group. Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units. Br J Ophthalmol 2018;102:1711–1716.
   PubMed Web of Science ®Google Scholar
• Shah PK, Prabhu V, Karandikar SS, et al. Retinopathy of prematurity: past, present and future. World J Clin Pediatr 2016;5:35–46.
   PubMedGoogle Scholar
• Du X, Ou X, Song T, et al. Adenosine A2B receptor stimulates angiogenesis by inducing VEGF and eNOS in human microvascular endothelial cells. Exp Biol Med (Maywood) 2015;240:1472–1479.
   PubMed Web of Science ®Google Scholar
• Xu Y, Wang Y, Yan S, et al. Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. EMBO Mol Med 2017;9:1263–1278.
   PubMed Web of Science ®Google Scholar
• Bakkiyanathan A, Nathan JR, Ravikumar S, et al. Anti-angiogenic effects of theophylline on developing zebrafish (Danio rerio) embryos. Biomed Prev Nutr 2012;2:174–178.
   Google Scholar
• Harris E, Schulzke SM, Patole SK. Pentoxifylline in preterm neonates: a systematic review. Paediatr Drugs 2010;12:301–311.
   PubMedGoogle Scholar
• Hasebe Y, Thomson LR, Dorey KC. Pentoxifylline inhibition of vasculogenesis in the neonatal rat retina. Invest Ophthalmol Vis Sci 2000;41:2774–2778.
   PubMed Web of Science ®Google Scholar
• Lauterbach R, Pawlik D, Kowalczyk D, et al. Effect of the immunomodulating agent, pentoxifylline, in the treatment of sepsis in prematurely delivered infants: a placebo-controlled, double-blind trial. Crit Care Med 1999;27:807–814.
   PubMed Web of Science ®Google Scholar
• Shabaan AE, Nasef N, Shouman B, et al. Pentoxifylline therapy for late-onset sepsis in preterm infants: a randomized controlled trial. Pediatr Infect Dis J 2015;34:e143.
   PubMed Web of Science ®Google Scholar
• Schüller SS, Kempf K, Unterasinger L, et al. Intravenous pentoxifylline is well tolerated in critically ill preterm infants with sepsis or necrotizing enterocolitis. Eur J Pediatr 2020;179:1325–1330.
   PubMed Web of Science ®Google Scholar
• Gude RP, Binda MM, Boquete AL, et al. Inhibition of endothelial cell proliferation and tumor-induced angiogenesis by pentoxifylline. J Cancer Res Clin Oncol 2001;127:625–630.
   PubMed Web of Science ®Google Scholar
• Koç E, Baş AY, Özdek Ş, et al. Turkish Neonatal and Turkish Ophthalmology Societies consensus guideline on the retinopathy of prematurity. Turk Pediatri Ars 2018;53:151–160.
   PubMedGoogle Scholar
• Gitto E, Karbownik M, Reiter RJ, et al. Effects of melatonin treatment in septic newborns. Pediatr Res 2001;50:756–760.
   PubMed Web of Science ®Google Scholar
• Papile LA, Munsick-Bruno G, Schaefer A. Relationship of cerebral intraventricular hemorrhage and early childhood neurologic handicaps. J Pediatr 1983;103:273–277.
   PubMed Web of Science ®Google Scholar
• Jobe AH, Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med 2001;163:1723–1729.
   PubMedGoogle Scholar
• Walsh MC, Kliegman RM. Necrotizing enterocolitis: treatment based on staging criteria. Ped Clin North Am 1986;33:179–201.
   PubMed Web of Science ®Google Scholar
• International Committee for the Classification of Retinopathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol 2005;123:991–999.
   PubMed Web of Science ®Google Scholar
• Wynn JL, Wong HR. Pathophysiology and treatment of septic shock in neonates. Clin Perinatol 2010;37:439–‐479.
   PubMed Web of Science ®Google Scholar
• Kim SJ, Port AD, Swan R, et al. Retinopathy of prematurity: a review of risk factors and their clinical significance. Surv Ophthalmol 2018;63:618–637.
   PubMed Web of Science ®Google Scholar
• Hellström A, Smith LE, Dammann O. Retinopathy of prematurity. Lancet 2013;382:1445–1457.
   PubMed Web of Science ®Google Scholar
• Wang YC, Chan OW, Chiang MC, et al. Red blood cell transfusion and clinical outcomes in extremely low birth weight preterm infants. Pediatr Neonatol 2017;58:216–222.
   PubMed Web of Science ®Google Scholar
• Lust C, Vesoulis Z, Jackups R, Jr, et al. Early red cell transfusion is associated with development of severe retinopathy of prematurity. J Perinatol 2019;39:393–400.
   PubMed Web of Science ®Google Scholar
• Chang JW. Risk factor analysis for the development and progression of retinopathy of prematurity. PLoS One 2019;14:e0219934.
   PubMed Web of Science ®Google Scholar
• Podraza W, Michalczuk B, Jezierska K, et al. Correlation of retinopathy of prematurity with bronchopulmonary dysplasia. Open Med (Wars) 2018;13:67–73.
   PubMedGoogle Scholar
• Isaza G, Arora S, Bal M, et al. Incidence of retinopathy of prematurity and risk factors among premature infants at a neonatal intensive care unit in Canada. J Pediatr Ophthalmol Strabismus 2013;50:27–32.
   PubMed Web of Science ®Google Scholar
• Speer EM, Dowling DJ, Ozog LS, et al. Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns. Pediatr Res 2017;81:806–816.
   PubMed Web of Science ®Google Scholar
• Schüller SS, Kramer BW, Villamor E, et al. Immunomodulation to prevent or treat neonatal sepsis: past, present, and future. Front Pediatr 2018;6:199.
   PubMed Web of Science ®Google Scholar
• Plotnikov MB, Aliev OI, Shamanaev AY, et al. Effects of pentoxifylline on hemodynamic, hemorheological, and microcirculatory parameters in young SHRs during arterial hypertension development. Clin Exp Hypertens 2017;39:570–578.
   PubMed Web of Science ®Google Scholar
• Zhang M, Xu YJ, Mengi SA, et al. Therapeutic potentials of pentoxifylline for treatment of cardiovascular diseases. Exp Clin Cardiol 2004;9:103–111.
   PubMedGoogle Scholar
• Pammi M, Haque KN. Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates. Cochrane Database Syst Rev 2015;3:CD004205.
   Google Scholar
• Cavallaro G, Filippi L, Bagnoli P, et al. The pathophysiology of retinopathy of prematurity: an update of previous and recent knowledge. Acta Ophthalmol 2014;92:2–20.
   PubMed Web of Science ®Google Scholar
• Nathan JR, Lakshmanan G, Michael FM, et al. Expression of adenosine receptors and vegf during angiogenesis and its inhibition by pentoxifylline-a study using zebrafish model. Biomed Pharmacother 2016;84:1406–1418.
   PubMed Web of Science ®Google Scholar
• Ji Q, Zhang L, Lv R, et al. Pentoxifylline decreases up-regulated nuclear factor kappa B activation and cytokine production in the rat retina following transient ischemia. Ophthalmologica 2006;220:217–224.
   PubMed Web of Science ®Google Scholar