63
Views
8
CrossRef citations to date
0
Altmetric
Research Article

AFLATOXIN—RECOGNITION, UNDERSTANDING, AND CONTROL WITH PARTICULAR EMPHASIS ON THE ROLE OF THE AGRICULTURAL RESEARCH SERVICE

Pages 143-169 | Published online: 02 Dec 2008

References

  • H. K. Abbas, R. M. Zablotowicz, H. A. Bruns, and C. A. Abel. (2006). Biocontrol of aflatoxin in corn by inoculation with non-aflatoxigenic Aspergillus flavus isolates. Biocontrol Science and Technology 16:437–449.
  • H. K. Abbas, W. T. Shier, and R. D. Cartwright. (2007). Effect of temperature, rainfall and planting date on aflatoxin and fumonisin contamination in commercial Bt and non-Bt corm hybrids in Arkansas. Phytoprotection 88:41–50.
  • H. K. Abbas, W. P. Williams, G. L Windham, H. C. Pringle, W. Xie, and W. T. Shier. (2002). Aflatoxin and Fumonisin contamination of commercial corn (Zea mays) hybrids in Mississippi. J. Agric. Food Chem. 50:5246–5254.
  • H. K. Abbas, and R. M. Zablotowicz. (2008). Non-aflatoxigenic Aspergillus flavus isolates. Patent serial no. US 7,361,499 B1. issued April 22, 2008.
  • H. K. Abbas, R. M. Zablotowicz, and H. A. Bruns. (2008). Modeling the colonization of maize by toxigenic and non-toxigenic Aspergillus flavus strains: implications for biological control. World Mycotoxin J. 1:333–340.
  • H. K. Abbas, R. M. Zablotowicz, M. Weaver, B. W. Horn, and W. T. Shier. (2005). Relationships between aflatoxin production, sclerotia formation and source among Mississippi Delta Aspergillus isolates. Eur. J. Plant Pathol. 112:283–287.
  • R. Allcroft. (1965). Aspects of aflatoxicosis in farm animals. In: Gerald Wogan. Mycotoxins in Foodstuffs. The MIT Press, 153–162. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964.
  • M. E. Alpert, M. S. R. Hutt, and C. S. Davidson. (1969). Primary hepatoma in Uganda, a prospective, clinical and epidemiological study in 46 patients. Am. J. Med. 46:794–802.
  • T. Asao, G. Buche, M. M. Abdel Kader, S. B. Chang, E. L. Wick, and G. N. Wogan. (1965). The structures of aflatoxin B1 & G1. In: Gerald Wogan. Mycotoxins in Foodstuffs. The MIT Press, 265–273. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964.
  • D. Bhatnagar, J. W. Cary, K. Ehrlich, J. Yu, and T. E. Cleveland. (2006). Understanding the genetics of regulation of aflatoxin production and Aspergillus flavus development. Mycopathologia 162:155–166.
  • D. Bhatnagar, T. E. Cleveland, N. P. Keller, and J. W. Cary. (1991). Control of aflatoxin contamination: Characterization of the toxin biosynthetic pathway. In: Proc. UJNR Protein Resources Panel 20th Annual Meeting. , TsukubaJapan, 76–100.
  • D. Bhatnagar, R. Proctor, G. A. Payne, J. R. Wilkinson, J. Yu, T. E. Cleveland, and W. Nierman. (2006). Genomics of mycotoxigenic fungi. In: D. Barug, D. Bhatnagar, H. P. van Egmond, J. W. van der Kamp, W. A. van Osenbruggen, and A. Visconti. The Mycotoxin Factbook. WageningenThe Netherlands: Wageningen Academic Publishers. 157–177.
  • D. Bhatnagar, K. Rajasekaran, G. A. Payne, R. L. Brown, J. Yu, and T. E. Cleveland. Applying the “omics” tools: genomics, proteomics, metabolomics for solving the aflatoxin contamination problem. World Mycotoxin Journal
  • W. P. Blount. (1960). A new turkey disease problem in England. Brit Oil and Cake Mills, Ltd., Quar. Poul. Bull. 27:1–3.
  • W. P. Blount. (1961). Turkey “X” disease. Turkeys 9 (2): 52, 55, 58, 61, 77
  • R. L. Brown, Z. Chen, S. V. Gembeh, T. E. Cleveland, D. Bhatnagar, and K. Howard. (2004). Identification of natural resistance in corn against mycotoxin-producing fungi. Res. Adv. Food Sci. 4:85–96.
  • W. R. Burg, and O. L. Shotwell. (1984). Aflatoxin in airborne dust generated from contaminated corn during harvest and at an elevator in 1980. J. Assoc. Offic. Anal. Chem. 67 (2):309–312.
  • W. R. Burg, O. L. Shotwell, and B. E. Saltzman. (1982). Measurement of airborne aflatoxins during the handling of contaminated corn. Am. Ind. Hyg. Assoc. J. 43:580–586.
  • W. H. Butler. (1965). Liver injury and aflatoxin (1965). In: Gerald Wogan. Mycotoxins in Foodstuffs. The MIT Press, 175–185. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964.
  • B. C. Campbell, J. H. Kim, J. Yu, N. Mahoney, N. G. Faria, K. L. Chan, R. J. Molyneux, D. Bhatnagar, T. E. Cleveland, G. S. May, and W. C. Nierman. (2007). Elucidation of the functional genomic basis of inhibition of aflatoxin biosynthesis by antioxidants. Proceedings of the 2007 Annual Multi-crop Aflatoxin/Fumonisin Elimination & Fungal Genomics Workshops. October22–24, 2007, Atlanta, GA, 31.
  • B. C. Campbell, J. H. Kim, J. Yu, R. J. Molyneux, N. Mahoney, J. D. Palumbo, K. L. Chan, D. Bhatnagar, T. E. Cleveland, and W. C. Nierman. (In press). Natural products as tools for chemogenomic analysis of mycotoxin biosynthesis and fungal stress-response systems. In: D. P. Siantar, and M. Trucksess. Mycotoxins and Food Allergens.
  • T. C. Campbell, and L. Stoloff. (1974). Implication of mycotoxins for human health. J. Agric. Food Chem. 22 (6):1006–1015.
  • P.-K. Chang, K. Matsushima, T. Takahashi, J. Yu, K. Abe, D. Bhatnagar, G.-F. Yuan, Y. Koyama, and T. E. Cleveland. (2007). Understanding nonaflatoxigenicity of Aspergillus sojae: a windfall of aflatoxin biosynthesis research. Appl. Microbiol. Biotechnol. 76:977–984.
  • A. Ciegler, R. E. Peterson, A. A. Lagoda, and H. H. Hall. (1966). Aflatoxin production and degradation by Aspergillus flavus in 20-liter fermentors. Appl. Microbiol. 14:826–833.
  • T. E. Cleveland, and D. Bhatnagar. (1990). Evidence for de novo synthesis of an aflatoxin pathway methyltransferase near the cessation of active growth and the onset of aflatoxin biosynthesis by Aspergillus parasiticus mycelia. Can. J. Microbiol. 36:1–5.
  • R. J. Cole. (1986). Etiology of turkey “X” disease in retrospect: a case for the involvement of cyclopiazonic acid. Mycotoxin Res. 2:3–7.
  • P. J. Cotty. (1992). Use of native Aspergillus flavus strains to prevent aflatoxin contamination. US Patent 5.171.686 December 15, 1992.
  • P. J. Cotty. (2006). Biocompetitive exclusion of toxigenic fungi. In: D. Barug, D. Bhatnagar, H. P. van Egmond, J. W. van der Kamp, W. A. van Osenbruggen, and A. Visconti. The Mycotoxin Factbook Food and Feed Topics. Wageningen, The Netherlands: Wageningen Academic Publishers. 179–197.
  • P. J. Cotty, L. Antilla, and P. J. Wakelyn. (2007). Competitive exclusion of aflatoxin producers: farmer driven research and development. In: C. Vincent, N. Goettel, and G. Lazarovits. Biological Control: A Global Perspective. Oxfordshire, UK: CAB International. 241–253.
  • Council for Agricultural Science and Technology. (2003). 8. Risk assessment regulations for mycotoxins. In: Mycotoxins: Risks in Plant, Animal and Human Systems, No. 139. Ames, IA: Council for Agricultural Science and Technology. 104–128.
  • S. J. Cysewski, R. L. Wood, A. C. Pier, and A. L. Baetz. (1978). Effects of aflatoxin on the development of acquired immunity to swine erysipelas. Am. J. Vet. Res. 39:445–448.
  • D. M. Dereszynski, S. A. Center, J. F. Randolph, M. B. Brooks, A. G. Hadden, K. S. Pallyada, S. P. McDonough, J. Messick, T. Stokol, K. L. Bischoff, S. Gluckman, and S. Y. Sanders. (2008). Clinical and clinocopathologic features of dogs that consumed foodborne hepatoxic aflatoxins: 72 cases (2005–2006). J. Am. Vet. Med. Assoc. 232 (9):1329–1337.
  • J. W. Dorner, and B. W. Horn. (2007). Separate and combined applications of Aspergillus flavus and A. parasiticus for biocontrol in peanuts. Mycopathologica. 163:215–223.
  • J. W. Dorner, . (2007). The experimental use program for determining the efficacy of Afla-guard for biocontrol of aflatoxin in corn. Proceedings of the 2007 Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshop p. 53–54 October - 24, 2007, Atlanta GA.
  • P. F. Dowd. (2005). Update on validation and distribution of a computer program for predicting mycotoxins in Midwest corn. Proceedings of the 18th Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshops, Raleigh, NC, October24–26, 114.
  • L. A. Goldblatt. (1969). Aflatoxin Scientific Background Control and Implications. New York: Academic Press.
  • J. E. Halver. (1965). Aflatoxicosis and rainbow trout hepatoma. In: Gerald Wogan. Mycotoxins in Foodstuffs. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964. The MIT Press, 209–230. .
  • R. D. Hartley, B. F. Nesbitt, and J. O'Kelley. (1963). Toxic metabolites of Aspergillus flavus. Nature 198:1056–1058.
  • R. G. Hendrickse, J. B. S. Coulter, S. M. Lamplugh, S. B. J. MacFarlane, T. E. Williams, M. I. A. Omer, G. I. Sulimen, and G. A. El-Zorgani. (1983). Aflatoxins and kwashiorkor: Epidemiology and clinical studies in Sudanese children and findings in autopsy liver samples from Nigeria and South Africa. Bull. Soc. Pathol. Exp. 76:559–566.
  • C. C. Holbrook, D. M. Wilson, P. Timper., B. Guo., and D. Sullivan. (2007). Is crop resistance through conventional breeding relevant to reducing aflatoxin contamination. Proceedings of the 2007 Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshop October 22–24, 2007, Atlanta GA. 82.
  • L. A Joens, A. C. Pier, and R. C. Cutlip. (1981). Effects of aflatoxin consumption on the clinical course of swine dysentery. Am. J. Vet. Res. 42:1170–1172.
  • F. H. Kratzer, D. Bandy, M. Wiley, and A. N. Booth. (1969). Aflatoxin effects in poultry. Proc. Soc. Expt. Biol. Med. 131:1281–1284.
  • H. F. Kraybill, and M. B. an dShimkin. (1964). Carcinogenesis related to foods contaminated by processing and fungal metabolites. Adv. Cancer Res. 8:191–248.
  • L. F. Kubena, R. B. Harvey, T. D. Phillips, D. E. Corrier, and W. E. Huff. (1990). Diminution of aflatoxicosis in growing chicks by dietary addition of a hydrated sodium calcium aluminosilicate. Poultry Sci. 69:727–735.
  • L. F. Kubena, W. E. Huff, R. B. Harvey, A. G. Yersin, M. H. Elissalde, D. A. Witzel, L. E. Giroir, and T. D. Phillips. (1991). Effect of a hydrated sodium calcium aluminosilicate on growing turkey poults during aflatoxicosis. Poultry Sci. 70:1823–1830.
  • M. C. Lancaster, F. P. Jenkins, and J. M. Philip. (1961). Toxicity associated with certain samples of groundnuts. Nature (London) 192:1095–1096.
  • E. B. Lillehoj, A. Logada, and W. F. Maisch. (1979). The fate of aflatoxin in naturally contaminated corn during the ethanol fermentation. Can. J. Microbiol. 25:911–914.
  • G. E. Mann, L. P. Codifer, H. K. Gardner, S. K. Koltun, and F. G. Dollear. (1970). Chemical inactivation of aflatoxins in peanut and cottonseed meals. J. Am Oil Chem. Soc. 47(5):173–176.
  • K. Mayfield, T. Isakeit, W. Xu, D. White, W. B. Henry, G. L. Windham, W. P. Williams, B. Guo, H. Abbas, S. Moore, Q. J. Raab, D. P. Gorman, J. M. Perkins, R. D. Lee, and M. D. Krakowsky. (2007). SERAT: The Southeast Region Aflatoxin Trial. Proceedings of the 2007 Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshop, Atlanta, GA, October22–24(2007), 97.
  • T. Michailides, and M. Doster. (2007). Aflatoxin control in pistachios: biocontrol using atoxigenic strains. Proceedings of the 2006 19th Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshops, October16–18(2006), 101.
  • M. Milner. (1965). Significance of mycotoxins in international protein food efforts. In: Gerald Wogan. Mycotoxins in Foodstuffs. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964. The MIT Press, 69–73.
  • P. M. Newberne. (1965). Carcinogenicity of aflatoxin-contaminated peanut meals. In: Gerald Wogan. Mycotoxins in Foodstuffs. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964. The MIT Press, 187–208.
  • P. M. Newberne, and W. H. Butler. (1969). Acute and chronic effects of aflatoxin on the liver of domestic and laboratory animals: a review. Cancer Res. 29:236–250.
  • W. P. Norred, and R. E. Morrissey. (1983). Effects of long term feeding of ammoniated, aflatoxin-contaminated corn to Fischer 344 rats. Toxicol. Appl. Pharmacol. 70:96–104.
  • R. C. Nuti, J. Dorner, R. Sorenson, and M. Lamb. (2006). Furrow diking for improved water use concerning preharvest aflatoxin contamination in peanut and corn. Proceedings of the 2006 19th Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshops, October16–18, (2007), 91.
  • A. G. Oettle. (1965). The etiology of primary carcinoma of the liver in Africa: a critical appraisal of previous ideas with an outline of the mycotoxin hypothesis. S.A. Tydskrif Vkir Genees-kunde, 9 October: 817–825.
  • G. A. Payne, W. C. Nierman, J. R. Wortman, B. L Pritchard, D. Brown, R. A. Dean, D. Bhatnagar, T. E. Cleveland, M. Machida, and J. Yu. (2006). Whole genome comparison of Aspergillus flavus and A. oryzae. Med. Myco. 44 (Suppl):9–11.
  • T. C. Pearson, and D. T. Wicklow. (2006). Detection of corn kernels infected by fungi. Transactions of the ASABE 49 (4):1235–1245.
  • A. C. Pier, R. E. Fichtner, and S. J. Cysewski. (1977). Effects of aflatoxin on the cellular immune system. Ann. Nut. Alim. 31:781–787.
  • A. C. Pier, and K. L. Heddleston. (1970). The effect of aflatoxin on immunity in turkeys. I. Impairment of actively acquired resistance to bacterial challenge. Avian Dis. 14:797–809.
  • C. Probst, H. Njapau, and P. J. Cotty. (2007). Outbreak of an acute aflatoxicosis in Kenya in 2004: identification of the causal agent. Appl. Environ. Microbiol. 73 (8):2762–2764.
  • R. D. K. Reye, G. Morgan, and J. Baral. (1963). Encephalopathy and fatty degeneration of the viscera: a disease entity in childhood. Lancet 2:749–752.
  • J. L Richard, A. C Pier, S. J Cysewski, and C. K. Graham. (1973). Effect of aflatoxin and aspergillosis on turkey poults. Avian Dis. 17:111–121.
  • J. L. Richard, and J. R. Thurston. (1975). Effect of aflatoxin on phagocytosis of Aspergillus fumigatus spores by rabbit alveolar macrophages. Appl. Microbiol. 30:44–77.
  • J. F. Robens. (1990). >A Perspective on Aflatoxin in Field Crops and Animal Food Products in the United States, A Symposium, January 23–24, 1990, Washington, DC, ARS-83, 157.
  • J. Robens, and F. K. Cardwell. (2003). The costs of mycotoxin management to the USA: management of aflatoxins in the United States. J. Toxicol. Toxin Rev. 22:139–153.
  • J. F. Robens, and J. L. Richard. (1992). Aflatoxins in human and animal health. Rev. Environ. Contam. Toxicol. 127:69–94.
  • W. J. Rogan, G. C. Yang, and R. D. Kimbrough. (1985). Aflatoxin and Reye's syndrome: a study of livers from disease cases. Arch. Environ. Health 40 (2):91–95.
  • W. D. Salmon, and P. M. Newberne. (1963). Occurrence of hepatomas in rats fed diets containing peanut meal as a major source of protein. Cancer Res. 23:571–575.
  • K. Sargeant, A. Shendan, J. O'Kelly, and R. B. A. Carnahan. (1961). Toxicity associated with certain samples of groundnuts. Nature 192:1096–1097.
  • G. E. Scott, N. Zummo, E. B. Lillehoj, N. W. Widstrom, M.S. Kang, D.R. West, G. A. Payne, T. E. Cleveland, O. H. Calvert, and B. A. Fortnum. (1991). Aflatoxin corn hybrids field inoculated with Aspergillus flavus. Agron. J. 83:595–598.
  • O. L. Shotwell, W. F. Kwolek, and C. W. Hesseltine. (1981). Aflatoxin in freshly harvested 1979 Georgia corn and formation after collection. J. Am. Oil Chem. Soc. 58 (12):980–983.
  • J. C. Silas, M. A. Harrison, J. A. Carpenter, and I. L. Roth. (1987). Airborne aflatoxin in corn processing facilities in Georgia. Am. Ind. Hyg. Assoc. J. 48 (3):198–201.
  • L. Stoloff. (1977). Aflatoxins—an overview. In: J. V. Rodricks, C. W. Hesseltine, and M. A. Mehlman. Mycotoxins in Human and Animal Health: Proceedings of a Conference on Mycotoxins in Human and Animal Health, convened at University of Maryland University College, Center of Adult Education, College Park, Maryland, October 4–8, 1976. 7–8.
  • L. Stoloff. (1980). Aflatoxin control: past and present. J. Assoc. Off. Anal. Chem. 63 (5):1067–1073.
  • R. A. Taber, and H. W. Schroeder. (1967). Aflatoxin-producing potential of isolates of the Aspergillus flavus—oryzae group from peanuts (Arachis hypogaea). Appl. Microbiol. 15:140–144.
  • T. Takahashi, P. K. Chang, K. Matsushima, J. Yu, K. Abe, D. Bhatnagar, T. E. Cleveland, and Y. Koyama. (2002). Nonfunctionality of Aspergillus sojae aflR in a strain of Aspergillus parasiticus with a disrupted aflRgene. Appl. Environ. Microbiol. 68 (8):3737–3743.
  • J. R. Thurston, J. L. Richard, S. J. Cysewski, A. C. Pier, and C. K. Graham. (1972). Effect of aflatoxin on complement activity in guinea pigs. Proc. Soc. Exp. Biol. Med. 138:300–303.
  • P. Timper, and C. Holbrook. (2007). Getting to the root of nematode involvement in aflatoxin contamination of peanut. Proceedings of the 2007 Annual Multi-crop Aflatoxin/Fumonisin Elimination & Fungal Genomics Workshops, October22–24, (2007), Atlanta, GA, 31.
  • D. J. Wagstaff. (1985). The use of epidemiology, scientific data, and regulatory authority to determine risk factors in cancers of some organs of the digestive tract. 3. Liver cancer. Reg. Toxicol. Pharmacol. 5:384–404.
  • D. J. Wagstaff. (1990). Epidemiologic studies of the association of aflatoxin exposure and human liver cancer. Proceedings of Symposium on Perspective on Aflatoxin in Field Crops and Animal Food Products in the United States, January23–24, (1990), Washington, DC, 141–147. ARS-83
  • D. T. Wicklow, and L. C. Marshall. (1999). Elimination of aflatoxin contaminated BGYF kernels through conventional breeding. Proceedings of the Aflatoxin Elimination Workshop, October20–22, (1999), Atlanta, GA, 4.
  • Gerald N. Wogan. (1965). Experimental toxicity and carcinogenicity of aflatoxins. In: Gerald Wogan. Mycotoxins in Foodstuffs. Proceedings of a symposium held at the Massachusetts Institute of Technology, March 18–19, 1964. The MIT Press, 163–173.
  • F. Wu, and Y. Liu. (2007). Cost effectiveness of aflatoxin control methods: economic incentives. Proceedings of the 2007 Annual Multicrop Aflatoxin/Fumonisin Elimination and Fungal Genomics Workshop, October22–24, (2007), Atlanta, GA.
  • F. Wu, J. D. Miller, and E. A. Casman. (2004). Bt corn and mycotoxin reduction: economic impacts in the United States and the developing world. J. Toxicol. Toxin. Rev. 23 (2&3):397–424.
  • J. Yu, D. Bhatnagar, and T. E. Cleveland. (2004). Completed sequence of aflatoxin pathway gene cluster in Aspergillus parasiticus. FEBS Lett. 564:126–130.
  • J. Yu, D. Bhatnagar, and K. C. Ehrlich. (2002). Aflatoxin biosynthesis. Rev. Iberoam. Micol. 19:191–200.
  • J. Yu, P. K. Chang, D. Bhatnagar, and T. E. Cleveland. (2000). Genes encoding cytochrome P450 and monooxygenase enzymes define one end of the aflatoxin pathway gene cluster in Aspergillus parasiticus. Appl. Microbiol. Biotechnol. 53 (5):583–590.
  • J. Yu, T. E. Cleveland, J. R. Wilkinson, B. C. Campbell, J. H. Kim, H. S. Kim, D. Bhatnagar, G. A. Payne, and W. C. Nierman. (2006). Aspergillus flavus expressed sequence tags and microarray as tools in understanding aflatoxin biosynthesis. Mycotoxin Res. 22 (1):16–21.
  • J. Yu, C. M. Ronning, J. R. Wilkinson, B. C. Campbell, G. A. Payne, D. Bhatnagar, T. E. Cleveland, and W. C. Nierman. (2007). Gene profiling for studying the mechanism of aflatoxin biosynthesis in Aspergillus flavus and A. parasiticus. J. Food Addit. Contam. 24 (10):1035–1042.
  • R. M. Zablotowicz, H. K. Abbas, and M. A. Locke. (2007). Population ecology of Aspergillus flavus associated with Mississippi Delta soils. Food Additives and Contaminants 24:1102–1108.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.