134
Views
7
CrossRef citations to date
0
Altmetric
Review Articles

Mycotoxicosis – diagnosis, prevention and control: past practices and future perspectives

&
Pages 99-114 | Received 20 Mar 2017, Accepted 04 Jun 2018, Published online: 17 Jul 2018

References

  • Abdelhamid, A.M., et al., 1990. Effect of low level of dietary aflatoxins on Baladi rabbits. Archiv fur tierernahrung, 40 (5-6), 517–537.
  • Abdel-Wahhab, M.A. and Aly, S.E., 2003. Antioxidants and radical scavenging properties of vegetable extracts in rats fed aflatoxin-contaminated diet. Journal of agricultural and food chemistry, 51 (8), 2409–2414.
  • Abdel-Wahhab, M.A. and Aly, S.E., 2005. Antioxidant property of Nigella sativa (black cumin) and Syzygium aromaticum (clove) in rats during aflatoxicosis. Journal of applied toxicology, 25 (3), 218–223.
  • Abdel-Wahhab, M.A., et al., 2007. Zizyphus spina-christi extract protects against aflatoxin B1 initiated hepatic carcinogenicity. African journal of traditional, complementary and alternative medicines, 4, 248–256.
  • Abdel-Wahhab, MA, Abdel-Galil, MM, El-Lithey M. 2005. Melatonin counteracts oxidative stress in rats fed an ochratoxin A contaminated diet.J Pineal Res38, 130–135
  • Abdel-Wahhab, M.A., Nada, S.A., and Amra, H.A., 1999. Effect of aluminosilicates and bentonite on aflatoxin-induced developmental toxicity in rat. Journal of applied toxicology, 19 (3), 199–204.
  • Abidin, Z., and Khatoon, A., 2012. Ruminal microflora, mycotoxin inactivation by ruminal microflora and conditions favouring mycotoxicosis in ruminants: a review. International journal of veterinary science, 1 (1), 36–43.
  • Abidin, Z., et al., 2013. Ameliorative effects of l-carnitine and vitamin E upon OTA induced haematological and serum biochemical alterations in white Leghorn cockerels. British poultry science, 54 (4), 471–477.
  • Abidin, Z., et al., 2016. Protective effects of l-carnitine upon toxicopathological alterations induced by ochratoxin A in white Leghorn cockerels. Toxin reviews, 35 (3-4), 157–164.
  • Abidin, Z., Khatoon, A., and Numan, M., 2011. Mycotoxins in broilers: pathological alterations induced by aflatoxins and ochratoxins, diagnosis and determination, treatment and control of mycotoxicosis. World's poultry science journal, 67 (03), 485–496.
  • Adams, M.R. and Motarjemi, Y., 1999. Basic food safety for health workers. World Health Organization.
  • Ademoyero, A.A. and Dalvi, R.R., 1983. Efficacy of activated charcoal and other agents in the reduction of hepatotoxic effects of a single dose of aflatoxin B1 in chickens. Toxicology letters, 16 (1-2), 153–157.
  • Ademoyero, A.A. and Hamilton, P.B., 1991. Mouth lesions in broiler chickens caused by scirpenol mycotoxins. Poultry science, 70 (10), 2082–2089.
  • Alan, A.R., Blowers, A., and Earle, E.D., 2004. Expression of a magainin-type antimicrobial peptide gene (MSI-99) in tomato enhances resistance to bacterial speck disease. Plant cell reports, 22 (6), 388–396.
  • Alegakis, A.K., et al., 1999. Deactivation of mycotoxins. I. An in vitro study of zearalenone adsorption on new polymeric adsorbents. Journal of environmental science and health. Part B, pesticides, food contaminants, and agricultural wastes, 34 (4), 633–644.
  • Alpsoy, L., Yildirim, A., and Agar, G., 2009. The antioxidant effects of vitamin A, C, and E on aflatoxin B1-induced oxidative stress in human lymphocytes. Toxicology and industrial health, 25 (2), 121–127.
  • Anuradha, S.T., et al., 2008. Transgenic tobacco and peanut plants expressing a mustard defensin show resistance to fungal pathogens. Plant cell reports, 27 (11), 1777–1786.
  • Araba, M., and Wyatt, R.D., 1991. Effects of sodium bentonite, hydrated sodium calcium aluminosilicate NovaSil™, and ethacal on aflatoxicosis in broiler chickens. Poultry science, 70, 6.
  • Atroshi, F., et al., 2000. Significance of apoptosis and its relationship to antioxidants after ochratoxin A administration in mice. Journal of pharmacy & pharmaceutical sciences, 3 (3), 281–291.
  • Avantaggiato, G., Havenaar, R., and Visconti, A., 2004. Evaluation of the intestinal absorption of deoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy of activated carbon and other adsorbent materials. Food and chemical toxicology, 42 (5), 817–824.
  • Aydın, G., et al., 2003. Histopathologic changes in liver and renal tissues induced by Ochratoxin A and melatonin in rats. Human and experimental toxicology, 22, 383–391
  • Bacon, C.W. and Hinton, D.M., 2007. Potential for control of seedling blight of wheat caused by Fusarium graminearum and related species using the bacterial endophyte Bacillus mojavensis. Biocontrol science and technology, 17 (1), 81–94.
  • Bailey, R.H., et al., 1998. Efficacy of various inorganic sorbents to reduce the toxicity of aflatoxin and T-2 toxin in broiler chickens. Poultry science, 77 (11), 1623–1630.
  • Baldi, A., et al., 2004. Evaluation of the protective effects of alpha-tocopherol and retinol against ochratoxin A cytotoxicity. The British journal of nutrition, 91 (4), 507–512.
  • Baptista, A.S., et al., 2004. The capacity of manno-oligosaccharides thermolysed yeast and active yeast to attenuate aflatoxicosis. World journal of microbiology and biotechnology, 20 (5), 475–481.
  • Barberis, C.L., et al., 2010. Food-grade antioxidants and antimicrobials to control growth and ochratoxin a production by Aspergillus section Nigri on peanut kernels. Journal of food protection, 73 (8), 1493–1501.
  • Basappa, S.C. and Shanta, T., 1996. Methods for detoxification of aflatoxins in foods and feeds: a critical appraisal. Journal of food technology, 33, 95–107.
  • Bauer, J., 1994. Moglichkeiten zur entgiftung mykotoxinhaltiger futtermittel. Monatsh veterinarmed, 49, 175–181.
  • Beaver, R.W., et al., 1990. Distribution of aflatoxins in tissues of growing pigs fed an aflatoxin-contaminated diet amended with a high affinity aluminosilicate sorbent. Veterinary and human toxicology, 32 (1), 16–18.
  • Bejaoui, H., et al., 2004. Ochratoxin A removal in synthetic and natural grape juices by selected oenological Saccharomyces strains. Journal of applied microbiology, 97 (5), 1038–1044.
  • Bell, C.H., 2000. Fumigation in the 21st century. Crop protection, 19 (8-10), 563–569.
  • Binder, E.M., et al., 2007. Worldwide occurrence of mycotoxins in commodities, feeds and feed ingredients. Animal feed science and technology, 137 (3-4), 265–282.
  • Blaney, B. J., 2001. Recent research on mycotoxins in Australia: chemistry, analytical methods and prevalence. In: Proceeding of 18th Conference Research Chemicals, Canberra, Australia.
  • Bonna, R.J., et al., 1991. Efficacy of hydrated sodium aluminosilicate and activated charcoal in reducing the toxicity of dietary aflatoxin to mink. Archives of environmental contamination and toxicology, 20 (3), 441–447.
  • Boonrod, K., et al., 2004. Single-chain antibodies against a plant viral RNA-dependent RNA polymerase confer virus resistance. Nature biotechnology, 22 (7), 856–862.
  • Bosch-Saadatmandi, C., et al., 2012. Ochratoxin A-induced cytotoxicity in liver (HepG2) cells: impact of serum concentration, dietary antioxidants and glutathione-modulating compounds. Journal of applied botany and food quality, 80, 179–186.
  • Brandt, K., et al., 2005. Production of bread wheat: control of quality and safety in organic production chains. http://www.organichaccp.org
  • Bricknell, L.K., Barry J.B., and Ng, J., 2008. Risk management for mycotoxin contamination of Australian maize. Australian Journal of Experimental Agriculture 48, 342–350.
  • Bricknell, L. K., NG, J. C., and Blaney, B. J., 2006. Introducing HACCP-based risk management for mycotoxin contamination in Australian maize. In: 6th terminal conference. Maize Association of Australia.
  • Buck, W.B. and Bratich, P.M., 1986. Activated charcoal: preventing unnecessary death by poisoning. Veterinary medicine, 73–77.
  • Bueno, D.J., et al., 2006. Lactobacillus casei CRL 431 and Lactobacillus rhamnosus CRL 1224 as biological controls for Aspergillus flavus strains. Journal of food protection, 69 (10), 2544–2548.
  • Burmeister, H.R., Ciegler, A., and Vesonder, R.F., 1979. Moniliformin, a metabolite of Fusarium moniliforme NRRL 6322: purification and toxicity. Applied and environmental microbiology, 37 (1), 11–13.
  • Bursian, S.J., et al., 1992. Efficacy of hydrated sodium calcium aluminosilicate in reducing the toxicity of dietary zearalenone to mink. Journal of applied toxicology, 12 (2), 85–90.
  • CAC (Codex Alimentarius Commission), 2003. Code of practice for the prevention and reduction of mycotoxin contamination in cereals, including annexes on ochratoxin A, zearalenone, fumonisins and tricothecenes. FAO/WHO Food Standards, viewed 6 January 2005.
  • Carlos, A.M., et al., 2004. Mycotoxins mechanisms of toxicity and methods of detection for identifying exposed individuals. Journal of land use, 19, 537–549.
  • Carson, M.S. and Smith, T.K., 1983. Role of bentonite in prevention of T-2 toxicosis in rats. Journal of animal science, 57 (6), 1498–1506.
  • Cary, J.W., et al., 2000. Transgenic expression of a gene encoding a synthetic antimicrobial peptide results in inhibition of fungal growth in vitro and in plants. Plant science, 153, 171–180.
  • Chakrabarti, A., et al., 2003. MSI-99, a magainin analogue, imparts enhanced disease resistance in transgenic tobacco and banana. Planta, 216 (4), 587–596.
  • Chakraborty, D. and Verma, R., 2010. Ameliorative effect of Emblica officinalis aqueous extract on ochratoxin-induced lipid peroxidation in the kidney and liver of mice. International journal of occupational medicine and environmental health, 23 (1), 63–73.
  • Chauhan, Y., Wright, G., and Rachaputi, N., 2006. Modelling mycotoxin contamination in maize. In: Water to gold 6th triennial conference of the Maize Association of Australia, Griffith, Australia. Maize Association of Australia
  • Chu, F. S., 1991. Detection and determination of mycotoxins, In: RP Sharma and DK Salunkhe, eds. Mycotoxins and phytoalexins. Boca Raton, FL: CRC Press, 33–79
  • Colvin, B.M., et al., 1989. Effect of a high affinity aluminosilicate sorbent on prevention of aflatoxicosis in growing pigs. Veterinary and human toxicology, 31 (1), 46–48.
  • Conner, M.W., et al., 1986. Toxicity of anguidine in mice. Fundamental and applied toxicology, 7 (1), 153–164.
  • Corcuera, L.A., et al., 2012. A polyphenol-enriched cocoa extract reduces free radicals produced by mycotoxins. Food and chemical toxicology, 50 (3-4), 989–995.
  • Corsetti, A., et al., 1998. Antimould activity of sourdough lactic acid bacteria: identification of a mixture of organic acids produced by Lactobacillus sanfrancisco CB1. Applied microbiology and biotechnology, 50 (2), 253–256.
  • Costa, S., et al., 2007. Catechins: natural free-radical scavengers against ochratoxin A-induced cell damage in a pig kidney cell line (LLC-PK1). Food and chemical toxicology, 45 (10), 1910–1917.
  • Dalvi, R.R., and Ademoyero, A.A., 1984. Toxic effects of aflatoxin B1 in chickens given feed contaminated with Aspergillus flavus and reduction of the toxicity by activated charcoal and some chemical agents. Avian diseases, 28 (1), 61–69.
  • Davidson, J.N., et al., 1987. Hydrated sodium calcium aluminosilicate decrease the bioavailability of aflatoxin in the chicken. Poultry science, 66, 89.
  • Decker, W.J., and Corby, D.G., 1980. Activated charcoal adsorbs aflatoxin B1. Veterinary and human toxicology, 22 (6), 388–389.
  • Degray, G., et al., 2001. Expression of an antimicrobial peptide via the chloroplast genome to control phytopathogenic bacteria and fungi. Plant physiology, 127 (3), 852–862.
  • Di Giacomo, C., et al., 2007. Protective effect of cyanidin 3-O-beta-D-glucoside on ochratoxin A-mediated damage in the rat. The British journal of nutrition, 98 (5), 937–943.
  • Diaz, G.J., et al., 1994. Individual and combined effects of T-2 toxin and DAS in laying hens. British poultry science, 35 (3), 393–405.
  • Diaz, G.J., Ariza, D. and Perilla, N.S., 2004. Method validation for the determination of ochratoxin A in green and soluble coffee by immunoaffinity column cleanup and liquid chromatography. Mycotoxin research, 20, 59–67.
  • Doerr, J.A., 1989. Effect of aluminosilicate on broiler chickens during aflatoxicosis. Poultry science, 68, 45.
  • Doerr, J.A., et al., 1974. A survey of T-2 toxin, ochratoxin, and aflatoxin for their effects on the coagulation of blood in young broiler chickens. Poultry science, 53 (5), 1728–1734.
  • Doll, S., et al., 2005. The efficacy of a modified aluminosilicate as a detoxifying agent in Fusarium toxin contaminated maize containing diets for piglets. Journal of animal physiology and animal nutrition, 89 (9-10), 342–358.
  • DPI&F., 2005a. Grain storage- basic design principles. Available from: http://storedgrain.com.au/grain-storage-basic-design-principles-dpif-note/ [Accessed 2 April 2006].
  • DPI&F., 2005b. Grain storage - insect control in stored grain, The State of Queensland (Department of Primary Industries & Fisheries) [Accessed 10 April 2006].
  • Dvorak, M. 1989. Ability of bentonite and natural zeolite to absorb aflatoxin from liquid media. Veterinary medicine, 34, 307–316.
  • Dwyer, M.R., et al., 1997. Effects of inorganic adsorbents and cyclopiazonic acid in broiler chickens. Poultry science, 76 (8), 1141–1149.
  • Edrington, T.S., et al., 1996. Hydrated sodium calcium aluminosilicate HSCAS, acidic HSCAS, and activated charcoal reduce urinary excretion of aflatoxin M1 in turkey poults. Lack of effect by activated charcoal on aflatoxicosis. Toxicology letters, 89 (2), 115–122.
  • Edrington, T.S., et al., 1997. Influence of a superactivated charcoal on the toxic effects of aflatoxin or T-2 toxin in growing broilers. Poultry science, 76 (9), 1205–1211.
  • Egmond, H.P.V. and Paulsch, W.E., 1986. Determination of mycotoxins. Pure and applied chemistry, 58 (2), 315–326.
  • El-Nekeety, A.A., et al., 2011. Antioxidant properties of Thymus vulgaris oil against aflatoxin-induce oxidative stress in male rats. Toxicon, 57 (7-8), 984–991.
  • El-Nezami, H., et al., 1998. Ability of dairy strains of lactic acid bacteria to bind a common food carcinogen, aflatoxin B1. Food and chemical toxicology, 36 (4), 321–326.
  • El-Nezami, H., et al., 2002a. Binding rather than metabolism may explain the interaction of two food-grade Lactobacillus strains with zearalenone and its derivative (0) alpha-zearalenol. Applied and environmental microbiology, 68 (7), 3545–3549.
  • El-Nezami, H.S., et al., 2002b. Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium. Food additives and contaminants, 19 (7), 680–686.
  • Eppley, R.M., 1975. Methods for the detection of trichothecenes. Journal-association of official analytical chemists, 58 (5), 906–907.
  • Espada, Y., et al., 1997. Fumonisin mycotoxicosis in broilers: plasma proteins and coagulation modifications. Avian diseases, 41 (1), 73–79.
  • FAO. 1991. Food nutrition and agriculture – food for the future. No 1. Available from: http://www.fao.org/docrep/U3550t/u3550t00.htm
  • Fan, T.S.L., Zhang, G.S., and Chu, F.S., 1984. An indirect enzyme-linked immunosorbent assay for T-2 toxin in biological fluids. Journal of food protection, 47 (12), 964–967.
  • Faucet-Marquis, et al., 2006. Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: correlation with DNA‐adduct formation. Molecular nutrition and food research, 50 (6), 530–542.
  • Flores, C.M., Domínguez, J.M., and Díaz-De-León, J., 1999. Modeling and experimental comparison of the differential adsorption of B1 and G1 aflatoxins on mineral aluminosilicate surfaces. Journal of environmental pathology, toxicology and oncology, 18 (3), 213–220.
  • Fremy, J.M. and Usleber, E., 2003. Policy on characterization of antibodies used in immunochemical methods of analysis for mycotoxins and phycotoxins. Journal of AOAC international, 86 (4), 868–871.
  • Friend, D.W., et al., 1984. Effect of adding potential vomitoxin (deoxynivalenol) detoxicants or a F. graminearum inoculated corn supplement to wheat diets fed to pigs. Canadian journal of animal science, 64 (3), 733–741.
  • Fuchs, S., et al., 2008. Detoxification of patulin and ochratoxin A, two abundant mycotoxins, by lactic acid bacteria. Food and chemical toxicology, 46 (4), 1398–1407.
  • Fukal, L., et al., 1990. The effect of a high aflatoxin B1 concentration in feed on the weights of organs and strength of bones in grown-up chickens. Bio chem vet, 26, 187–191.
  • Fusi, E., et al., 2010. Alpha-tocopherol counteracts the cytotoxicity induced by ochratoxin a in primary porcine fibroblasts. Toxins, 2 (6), 1265–1278.
  • Galey, F.D., et al., 1987. Therapeutic efficacy of superactive charcoal in rats exposed to oral lethal doses of T-2 toxin. Toxicon, 25 (5), 493–499.
  • Galvano, F., et al., 1997. Activated carbons. In vitro affinity for fumonisin B1 and relation of adsorption ability to physicochemical parameters. Journal of food protection, 60 (8), 985–991.
  • Galvano, F., et al., 1998. Activated carbons: in vitro affinity for ochratoxin A and deoxynivalenol and relation of adsorption ability to physicochemical parameters. Journal of food protection, 61 (4), 469–475.
  • Gedek, B., 1980. Kompendium der medizinische mykologie (p.395). Berlin und Hamburg: Verlag Paul Parey.
  • Gowda, N.K., et al., 2009. Antioxidant efficacy of curcuminoids from turmeric (Curcuma longa L.) powder in broiler chickens fed diets containing aflatoxin B1. The British journal of nutrition, 102 (11), 1629–1634.
  • Greenway, J.A. and Puls, R., 1976. Fusariotoxicosis from barley in British Columbia. I. Natural occurrence and diagnosis. Canadian journal of comparative medicine, 40 (1), 12.
  • Grosse, Y., et al., 1997. Retinol, ascorbic acid and alpha-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and zearalenone. Cancer letters, 114 (1-2), 225–229.
  • Guerra, M.C., et al., 2005. Cyanidin-3-O-beta-glucopyranoside, a natural free-radical scavenger against aflatoxin B1- and ochratoxin A-induced cell damage in a human hepatoma cell line (Hep G2) and a human colonic adenocarcinoma cell line (CaCo-2). British journal of nutrition, 94 (02), 211–220.
  • Hagler, W. M., JR. 1991. Potential for detoxification of mycotoxin-contaminated commodities. In: GA Bray and DH Ryan, eds. Mycotoxins, cancer and health (Pennington Center Nutrition Series). Baton Rouge, LA: Louisiana State University Press, 253–269.
  • Halasz, A., et al., 2009. Decontamination of mycotoxin-contaminating food and feed by biodegradation. Food reviews international, 25 (4), 284–298.
  • Harvey, R. B., et al., 1989. Prevention of clinical signs of aflatoxicosis with hydrated sodium calcium aluminosilicate added to diets, Proceedings of the 20th Annual Meeting of the American Association of Swine Practitioners, Des Moines, Iowa, 99–102.
  • Harvey, R.B., et al., 1991. Diminution of aflatoxin toxicity to growing lambs by dietary supplementation with hydrated sodium calcium aluminosilicate. American journal of veterinary research, 52 (1), 152–156.
  • Harvey, R.B., et al., 1993. Efficacy of zeolitic ore compounds on the toxicity of aflatoxin to growing broiler chickens. Avian diseases, 37 (1), 67–73.
  • Haschek, W.M., et al., 1992. Characterization of fumonisin toxicity in orally and intravenously dosed swine. Mycopathologia, 117, 83–96.
  • Hatch, R.C., et al., 1982. Induced acute aflatoxicosis in goats: treatment with activated charcoal or dual combinations of oxytetracycline, stanozolol, and activated charcoal. American journal of veterinary research, 43 (4), 644–648.
  • Hayes, A.W., 1981. Mycotoxin teratogenecity and mutagenicity. Boca Raton, FL: CRC Press.
  • Hayes, M.A. and Schiefer, H.B., 1979. Quantitative and morphological aspects of cutaneous irritation by trichothecene mycotoxins. Food and cosmetics toxicology, 17 (6), 611–613621.
  • Hedman, R., et al., 1995. Effects of feeding nivalenol-contaminated diets to male broiler chickens. Poultry science, 74, 620–625.
  • Hiatt, E.E., Hill, N.S., and Hiatt, E.N., 2001. Monoclonal antibodies incorporated into Neotyphodium coenophialum fungal cultures: inhibition of fungal growth and stability of antibodies. Fungal genetics and biology, 33 (2), 107–114.
  • Hoehler, D., and Marquardt, R.R., 1996. Influence of vitamins E and C on the toxic effects of ochratoxin A and T-2 toxin in chicks. Poultry science, 75 (12), 1508–1515.
  • Hu, Z.Q., et al., 2008. Antibody-mediated prevention of Fusarium mycotoxins in the field. International journal of molecular sciences, 9 (10), 1915–1926.
  • Huebner, H.J., et al., 1999. Molecular characterization of high affinity, high capacity clays for the equilibrium sorption of ergotamine. Food additives and contaminants, 16 (4), 159–171.
  • Huff, W.E., et al., 1988. Mycotoxin interactions in poultry and swine. Journal of animal science, 66 (9), 2351–2355.
  • Huff, W.E., et al., 1992. Efficacy of hydrated sodium calcium aluminosilicate to reduce the individual and combined toxicity of aflatoxin and ochratoxin A. Poultry science, 71 (1), 64–69.
  • Hundhausen, C., et al., 2005. Effect of vitamin E and polyphenols on ochratoxin A-induced cytotoxicity in liver (HepG2) cells. Journal of plant physiology, 162 (7), 818–822.
  • Huwig, A., et al., 2001. Mycotoxin detoxication of animal feed by different adsorbents. Toxicology letters, 122 (2), 179–188.
  • Jeswal, P., 1998. Antidotal effect of grape juice (Vitis vinifera) on ochratoxin A caused hepatorenal carcinogenesis in mice (Mus musculus). Cytobios, 93 (373), 123–128.
  • Jobling, S.A., et al., 2003. Immunomodulation of enzyme function in plants by single-domain antibody fragments. Nature biotechnology, 21 (1), 77–80.
  • Joseph, G.S., et al., 2005. Antiaflatoxigenic and antioxidant activities of Garcinia extracts. International journal of food microbiology, 101 (2), 153–160.
  • Jun, H.S., Kim, S.E., and Sung, M.K., 2002. Protective effect of soybean saponins and major antioxidants against aflatoxin B1-induced mutagenicity and DNA-adduct formation. Journal of medicinal food, 5 (4), 235–240.
  • Kaaya, A.N., et al., 2005. The effect of delayed harvest on moisture content, insect damage, moulds and aflatoxin contamination of maize in Mayuge district of Uganda. Journal of the science of food and agriculture, 85 (15), 2595–2599.
  • Kells, S.A., et al., 2001. Efficacy and fumigation characteristics of ozone in stored maize. Journal of stored products research, 37 (4), 371–383.
  • Kensler, T.W., et al., 1985. Modification of aflatoxin B1 binding to DNA in vivo in rats fed phenolic antioxidants, ethoxyquin and a dithiothione. Carcinogenesis, 6 (5), 759–763.
  • Khatoon, A., et al., 2013. Amelioration of ochratoxin A-induced immunotoxic effects by silymarin and vitamin E in white leghorn cockerels. Journal of immunotoxicology, 10 (1), 25–31.
  • Kim, J.H., et al., 2008. Elucidation of the functional genomics of antioxidant-based inhibition of aflatoxin biosynthesis. International journal of food microbiology, 122 (1-2), 49–60.
  • Kitchen, D.N., Carlton, W.W., and Tuite, J., 1977. Ochratoxin A and citrinin induced nephrosis in beagle dogs I. Clinical and clinicopathological features. Veterinary pathology, 14 (2), 154–172.
  • Kubena, L.F., et al., 1988. Modulation of aflatoxicosis in growing chickens by dietary addition of a hydrated sodium calcium aluminosilicate. Poultry science, 67, 106.
  • Kubena, L.F., et al., 1990. Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and T-2 toxin. Poultry science, 69 (7), 1078–1086.
  • Kubena, L.F., et al., 1991. Effects of hydrated sodium calcium aluminosilicates on growing turkey poults during aflatoxicosis. Poultry science, 70 (8), 1823–1830.
  • Kubena, L.F., et al., 1993. Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and diacetoxyscirpenol. Poultry science, 72 (1), 51–59.
  • Kubena, L.F., et al., 1994. Influence of ochratoxin A and diacetoxyscirpenol singly and in combination on broiler chickens. Poultry science, 73 (3), 408–415.
  • Kubena, L.F., et al., 1998. Effects of hydrated sodium calcium aluminosilicate T-Bind™ on mycotoxicosis in young broiler chickens. Poultry science, 77 (10), 1502–1509.
  • Kumar, R., et al., 2007. Evaluation of Chenopodium ambrosioides oil as a potential source of antifungal, antiaflatoxigenic and antioxidant activity. International journal of food microbiology, 115 (2), 159–164.
  • Kutz, R.E., et al., 2009. Efficacy of Solis, Novasil Plus, and MTB-100 to reduce aflatoxin M1 levels in milk of early to mid lactation dairy cows fed aflatoxin B1. Journal of dairy science, 92 (8), 3959–3963.
  • Ledoux, D.R., et al., 1995. Effects of feeding Fusarium fujikuroi culture material, containing known levels of moniliformin, in young broiler chicks. Poultry science, 74 (2), 297–305.
  • Ledoux, D.R., et al., 1999. Efficacy of a hydrated sodium calcium aluminosilicate to ameliorate the toxic effects of aflatoxin in broiler chicks. Poultry science, 78 (2), 204–210.
  • Lemke, S.L., Grant, P.G., and Phillips, T.D., 1998. Adsorption of zearalenone by organophilic montmorillonite clay. Journal of agricultural and food chemistry, 46 (9), 3789–3796.
  • Li, Q.Q., et al., 2001. Enhanced disease resistance conferred by expression of an antimicrobial magainin analog in transgenic tobacco. Planta, 212 (4), 635–639.
  • Lindemann, M.D., et al., 1989. Evaluation of potential ameliorators of aflatoxicosis in weanling/growing swine. Journal of animal science, 67, 36.
  • Lindemann, M.D., et al., 1993. Potential ameliorators of aflatoxicosis in weanling/growing swine. Journal of animal science, 71 (1), 171–178.
  • Liu, Y.L., et al., 1988. Protection by 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) against the hepatotoxicity of aflatoxin B1 in the rat. Toxicology and applied pharmacology, 93 (3), 442–451.
  • Lorenzana, R.M., et al., 1985. Experimental T-2 toxicosis in swine. I. Changes in cardiac output, aortic mean pressure, catecholamines, 6-keto-PGF thromboxane B2, and acid-base parameters. Fundamental and applied toxicology, 5 (5), 879–892.
  • Ma, J.K.C., et al., 2005. Molecular farming for new drugs and vaccines: current perspectives on the production of pharmaceuticals in transgenic plants. EMBO reports, 6 (7), 593–599.
  • Malekinejad, H., Farshid, A.A., and Mirzakhani, N., 2011. Liquorice plant extract reduces ochratoxin A-induced nephrotoxicity in rats. Experimental and toxicologic pathology, 63 (1-2), 125–130.
  • Mandel, H.G., et al., 1987. Metabolic basis for the protective effect of the antioxidant ethoxyquin on aflatoxin B1 hepatocarcinogenesis in the rat. Cancer research, 47 (19), 5218–5223.
  • Maragos, C., 2009. Fluorescence polarization immunoassay of mycotoxins: a review. Toxins, 1 (2), 196–207.
  • Marasas, W.F.O., et al., 1969. Toxic effects on trout, rats, and mice of T-2 toxin produced by the fungus Fusarium tricinctum (Cd.) Snyd. et Hans. Toxicology and applied pharmacology, 15 (2), 471–482.
  • Marı́n, S., et al., 2000. Selective effect of propionates on maize mycoflora and impact on fumonisin B1 accumulation. Journal of stored products research, 36 (2), 203–214.
  • Marth, E.H. and Doyle, M.P., 1979. Update on molds: degradation of aflatoxin. Food technology, 33, 81.
  • Masimango, N., et al., 1978. The role of adsorption in the elimination of aflatoxin B1 from contaminated media. European journal of applied microbiology and biotechnology, 6 (1), 101–105.
  • Mckenzie, K.S., et al., 1997. Oxidative degradation and detoxification of mycotoxins using a novel source of ozone. Food and chemical toxicology, 35 (8), 807–820.
  • Meki, A.R.M. and Hussein, A.A., 2001. Melatonin reduces oxidative stress induced by ochratoxin A in rat liver and kidney. Comparative biochemistry and physiology: toxicology and pharmacology, 130 (3), 305–313.
  • Miazzo, R., et al., 2000. Efficacy of synthetic zeolite to reduce the toxicity of aflatoxin in broiler chicks. Poultry science, 79 (1), 1–6.
  • Miceli, A., et al., 2003. Polyphenols, resveratrol, antioxidant activity and ochratoxin A contamination in red table wines, controlled denomination of origin (DOC) wines and wines obtained from organic farming. Journal of wine research, 14 (2-3), 115–120.
  • Mitsuhara, I., et al., 2006. Corn as a source of antifungal genes for genetic engineering of crops for resistance to aflatoxin contamination. Plant biotechnology, 23, 63–69.
  • Mombelli, B. and Gismondo, M.R., 2000. The use of probiotics in medical practice. International journal of antimicrobial agents, 16 (4), 531–536.
  • Morris, C.M., et al., 1999. The individual and combined effects of feeding moniliformin, supplied by Fusarium fujikuroi culture material, and deoxynivalenol in young turkey poults. Poultry science, 78 (8), 1110–1115.
  • Munkvold, G.P., 2003. Epidemiology of Fusarium diseases and their mycotoxins in maize ears. European Journal of Plant Pathology, 109, 705–713.
  • Naaz, F., Javed, S., and Abdin, M.Z., 2007. Hepatoprotective effect of ethanolic extract of Phyllanthus amarus Schum. et Thonn. on aflatoxin B1-induced liver damage in mice. Journal of ethnopharmacology, 113 (3), 503–509.
  • Napolitano, A., et al., 2007. Natural occurrence of ochratoxin A and antioxidant activities of green and roasted coffees and corresponding byproducts. Poultry science, 78, 1110–1115.
  • Natour, R.M. and Yousef, S.M., 1998. Adsorption efficiency of diatomaceous earth for mycotoxin. Arab Gulf journal of scientific research, 16, 113–127.
  • Nesci, A., Ferrari, L., and Etcheverry, M., 2008. Effect of synthetic antioxidants on stored maize grain mycoflora in situ. Journal of the science of food and agriculture, 88 (5), 797–804.
  • Nesci, A., Rodriguez, M., and Etcheverry, M., 2003. Control of Aspergillus growth and aflatoxin production using antioxidants at different conditions of water activity and pH. Journal of applied microbiology, 95 (2), 279–287.
  • Nickel, H., et al., 2008. Plantibody-mediated inhibition of the Potato leafroll virus P1 protein reduces virus accumulation. Virus research, 136 (1-2), 140–145.
  • Nourozian, J., Etebarian, H.R., and Khodakaramianm, G., 2006. Biological control of Fusarium graminearum on wheat by antagonistic bacteria. Songklanakarin journal of science and technology, 28, 29–38.
  • Ozçelik, N., Soyöz, M., and Kilinç, I., 2004. Effects of ochratoxin A on oxidative damage in rat kidney: protective role of melatonin. Journal of applied toxicology, 24 (3), 211–215.
  • Palabiyik, S.S., et al., 2013. Protective effect of lycopene against ochratoxin A induced renal oxidative stress and apoptosis in rats. Experimental and toxicologic pathology, 65 (6), 853–861.
  • Palyusik, M. and Koplik-Kovacs, E., 1975. Effect on laying geese of feeds containing the fusariotoxins T2 and F2. Acta veterinaria academiae scientiarum hungaricae, 25 (4), 363.
  • Parlat, S.S., Yildiz, A.O. and Oguz, H., 1999. Effect of clinoptilolite on performance of Japanese quail (Coturnix coturnix japonica) during experimental aflatoxicosis. British poultry science, 40, 495–500.
  • Patharajan, S., et al., 2011. Potential of yeast antagonists on in vitro biodegradation of ochratoxin A. Food control, 22 (2), 290–296.
  • Patterson, R. and Young, L.G., 1993. Efficacy of hydrated sodium calcium aluminosilicates, screening and dilution in reducing the effects of mold contaminated corn in pigs. Canadian journal of animal science, 73 (3), 615–624.
  • Peltonen, K., et al., 2001. Aflatoxin B1 binding by dairy strains of lactic acid bacteria and bifidobacteria. Journal of dairy science, 84 (10), 2152–2156.
  • Pereira, A.M., et al., 2007. Effeito imediato e latente da fumigacao com ozonio na qualidade dos graos de milho. Revista Brasileira de Armazenamento, 32, 100–110.
  • Peschen, D., et al., 2004. Fusion proteins comprising a Fusarium-specific antibody linked to antifungal peptides protect plants against a fungal pathogen. Nature biotechnology, 22 (6), 732–738.
  • Phillips, T.D., et al., 1988. Hydrated sodium calcium aluminosilicate: a high affinity sorbent for aflatoxin. Poultry science, 67 (2), 243–247.
  • Phillips, T.D., et al., 1990. Detection and detoxification of aflatoxins: prevention of aflatoxicosis and aflatoxin residues with hydrated sodium calcium aluminosilicate. Veterinary and human toxicology, 32, 15–19.
  • Pineiro, M., 2001. Manual on the application of the HACCP system in mycotoxin prevention and control. vol. 73. Food & Agriculture Org.
  • Pool-Zobel, B.L., Münzner, R., and Holzapfel, W.H., 1993. Antigenotoxic properties of lactic acid bacteria in the S. typhimurium mutagenicity assay. Nutrition and cancer, 20 (3), 261–270.
  • Pool-Zobel, B.L., et al., 1996. Lactobacillus and bifidobacterium-mediated antigenotoxic in the colon of rats. Nutrition and cancer, 26 (3), 365–380.
  • Poppenga, R.H., et al., 1987. The assessment of a general therapeutic protocol for the treatment of acute T-2 toxicosis in swine. Veterinary and human toxicology, 29 (3), 237–239.
  • Prakash, B., et al., 2010. Efficacy of chemically characterized Piper betle L. essential oil against fungal and aflatoxin contamination of some edible commodities and its antioxidant activity. International journal of food microbiology, 142 (1-2), 114–119.
  • Prakash, B., et al., 2011. Efficacy of chemically characterized Ocimum gratissimum L. essential oil as an antioxidant and a safe plant based antimicrobial against fungal and aflatoxin B 1 contamination of spices. Food research international, 44 (1), 385–390.
  • Premalatha, B. and Sachdanandam, P., 1999. Semecarpus anacardium L. nut extract administration induces the in vivo antioxidant defence system in aflatoxin B 1 mediated hepatocellular carcinoma. Journal of ethnopharmacology, 66 (2), 131–139.
  • Rafai, P., et al., 1995. Effect of various levels of T-2 toxin on the immune system of growing pigs. Veterinary record, 136 (20), 511–514.
  • Rajasekaran, K., et al., 2005. Disease resistance conferred by the expression of a gene encoding a synthetic peptide in transgenic cotton (Gossypium hirsutum L.) plants. Plant biotechnology journal, 3 (6), 545–554.
  • Rajasekaran, K., et al., 2008. Development of a GFP-expressing Aspergillus flavus strain to study fungal invasion, colonization, and resistance in cottonseed. Mycopathology, 165 (2), 89–97.
  • Rajasekaran, K., Jaynes, J.M., and Cary, J.W., 2009. Transgenic expression of lytic peptides in food and feed crops to control phytopathogens and preharvest mycotoxin contamination. Journal of the American chemical society, 1031, 119–142.
  • Raju, M.V.L.N. and Devegowda, G., 2000. Influence of esterified glucomannan on performance and organ morphology, serum biochemistry and haematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin and T-2 toxin). British poultry science, 41 (5), 640–650.
  • Ramos, A. J., and Hernandez, E., 1993. Resin colestiramina: un adsorbente de zearalenona de alta afinidad. Procc. XIV Congreso Nacional de Microbiologia, 8-11 Septiembre, Zaragoza, Spain.
  • Ramos, A. J., Fink-Gremmels, J., and Hernández, E., 1996. Prevention of toxic effects of mycotoxins by means of nonnutritive adsorbent compounds. Journal of food protection, 59 (6), 631–641.
  • Reddy, K.R.N., et al., 2009. Mycotoxin contamination of commercially important agricultural commodities. Toxin Reviews, 28, 154–168.
  • Renzulli, C., et al., 2004. Effects of rosmarinic acid against aflatoxin B1 and ochratoxin‐A‐induced cell damage in a human hepatoma cell line (Hep G2). Journal of applied toxicology, 24 (4), 289–296.
  • Reverberi, M., et al., 2005. Antioxidant enzymes stimulation in Aspergillus parasiticus by Lentinula edodes inhibits aflatoxin production. Applied microbiology and biotechnology, 69 (2), 207–215.
  • Ribar, S., and Mezaric, M., 1998. Fumonisins – mycotoxins produced by Fusarium moniliforme. Lijec vjesnik, 120, 85–91.
  • Rodricks, J. V., and Eppley, R. M., 1974. Stachybotrys and stachybotryotoxicosis. In: IFH Purchase ed. Mycoroxins. Amsterdam: Elsevier, 181
  • Rosa, C.A.R., et al., 2001. Evaluation of the efficacy of bentonite from the south of Argentina to ameliorate the toxic effects of aflatoxin in broilers. Poultry science, 80 (2), 139–144.
  • Rotter, B.A., Prelusky, D.B., and Pestka, J.J., 1996. Toxicology of deoxynivalenol (vomitoxin). Journal of toxicology and environmental health, 48 (1), 1–34.
  • Rotter, R.G., Frohlich, A.A. and Marquardt, R.R., 1989. Influence of dietary charcoal on ochratoxin A toxicity in Leghorn chicks. Canadian journal of veterinary research, 53, 449.
  • Roy, U., et al., 1996. Production of antifungal substance by Lactococcus lactis subsp. lactis CHD-283. International journal of food microbiology, 32 (1-2), 27–34.
  • Rozado, A.F., et al., 2008. Applicao de ozonio contra Sitophilus zeamais e Tribolium castaneum em milho armazenado. Revista brasileira de engenharia agrícola e ambiental, 12 (3), 282–285.
  • Sands, D.C., McIntyre, J.L., and Walton, G.S., 1976. Use of activated charcoal for the removal of patulin from cider. Applied and environmental microbiology, 32 (3), 388–391.
  • Santin, E., et al., 2003. Evaluation of the efficacy of Saccharomyces cerevisiae cell wall to ameliorate the toxic effects of aflatoxin in broilers. International Journal of Poultry Science, 2, 341–344.
  • Santillan, E.M., et al., 2006. Antigenotoxic effect of Saccharomyces cerevisiae on the damage produced in mice fed with aflatoxin B1 contaminated corn. Food and chemical toxicology, 44 (12), 2058–2063.
  • Santini, A., et al., 2011. Influence of different coffee drink preparations on ochratoxin A content and evaluation of the antioxidant activity and caffeine variations. Food contamination, 22 (8), 1240–1245.
  • Schall, N., Simmler-Hübenthal, H., Feldhaus Hermann, G., 2000. Mykotoxin-Adsorbens. Ger. Offen. DE 19900813.
  • Scheideler, S.E., 1993. Effects of various types of aluminosilicates and aflatoxin B1 on aflatoxin toxicity, chick performance, and mineral status. Poultry science, 72 (2), 282–288.
  • Schell, T.C., et al., 1993. Effects of feeding aflatoxin-contaminated diets with and without clay to weanling and growing pigs on performance, liver-function, and mineral metabolism. Journal of animal science, 71 (5), 1209–1218.
  • Schiefer, H.B., 1986. Pathology of mycotoxicoses: possibilities and limits of a diagnosis. Pure and applied chemistry, 58 (2), 351–356.
  • Schoental, R., 1984. Mycotoxins and the Bible. Perspectives in biology and medicine, 28 (1), 117–120.
  • Schoental R., 1991. Mycotoxins and the Bible. Perspectives in biology and medicine, 28, 117–120.
  • Schoental, R., 1994. Mycotoxins in food and the plague in Athens. Journal of nutritional and environmental medicine, 4 (1), 83–85.
  • Schoental, R. and Jotie, A.Z., 1974. Lesions induced in rodents by extracts from cultures of Fusarium poae and F. sporotrichioides. The journal of pathology, 112 (1), 37.
  • Schuh, M. and Baumgartner, W., 1988. Mikrobiologisch und mykotoxikologisch kontaminierte Futtermittel als Krankheitsursache bei Rindern. Wiener tierarztliche monatsschrift, 75, 329–332.
  • Schweighardt, H., et al., 1980. Analysis of the fusariotoxins zearalenone and vomitoxin (deoxynivalenol) in human foods and animal feeds by high-performance liquid chromatography (HPLC). Chromatography, 13 (7), 447–450.
  • Selvi, A.T., Joseph, G.S., and Jayaprakasha, G.K., 2003. Inhibition of growth and aflatoxin production in Aspergillus flavus by Garcinia indica extract and its antioxidant activity. Food microbiology, 20 (4), 455–460.
  • Shah, N.P., 2000. Probiotic bacteria: selective enumeration and survival in dairy foods. Journal of dairy science, 83 (4), 894–907.
  • Shapira, R., 2004. Control of mycotoxins in storage and techniques for their decontamination. In: N. Magan and M. Olsen, eds. Mycotoxins in food: detection and control. Cambridge: Woodhead Publishing Ltd, 190–223.
  • Shelef, L.A. and Chin, B., 1980. Effect of phenolic antioxidants on the mutagenicity of aflatoxin B1. Applied and environmental microbiology, 40 (6), 1039–1043.
  • Shetty, P.H., Hald, B., and Jespersen, L., 2007. Surface binding of aflatoxin B1 by Saccharomyces cerevisiae strains with potential decontaminating abilities in indigenous fermented foods. International journal of food microbiology, 113 (1), 41–46.
  • Shim, W.B., et al., 2004. Fluorescence polarization immunoassay based on a monoclonal antibody for the detection of ochratoxin A. International journal of food science and technology, 39 (8), 829–837.
  • Smith, T.K., 1982. Dietary influences on excretory pathways and tissue residues of zearalenone and zearalenols in the rat. Canadian journal of physiology and pharmacology, 60 (12), 1444–1449.
  • Solfrizzo, M., et al., 2001. Ineffectiveness of activated carbon in reducing the alteration of sphingolipid metabolism in rats exposed to fumonisin-contaminated diets. Food and chemical toxicology, 39 (5), 507–511.
  • Sousa, A.H., et al., 2008. Ozone as a management alternative against phosphine-resistant insect pests of stored products. Journal of stored products research, 44 (4), 379–385.
  • Sova, Z., et al., 1991. Hematological and histological response to the diets containing aflatoxin B1 and zeolite in broilers of domestic fowl. Acta Veterinaria Brunensis, 60 (1), 31–40.
  • Soyoz, M., et al., 2004. The effects of ochratoxin A on lipid peroxidation and antioxidant enzymes: a protective role of melatonin. Cell biology and toxicology, 20 (4), 213–219.
  • Stanley, V.G., et al., 1993. The use of Saccharomyces cerevisiae to suppress the effects of aflatoxicosis in broiler chicks. Poultry science, 72 (10), 1867–1872.
  • Steele, R.H. and Wilhelm, D.L., 1970. The inflammatory reaction in chemical injury. III. Leucocytosis and other histological changes induced by superficial injury. British journal of experimental pathology, 51, 265.
  • Stiles, J. and Bullerman, L. B., 2002. Inhibition of Fusarium species and mycotoxin production by Bacillus pumilus NEB1 and Lactobacillus rhamnosus VT1. In: H.W. Dehne, U. Gisi, K. H. Kuck, P. E. Russell, L. H. Bonn, eds, Proceedings of 13th International Reinhardsbrunn Symposium. In: Modern Fungicides and Antifungal Compounds III Agro Concept GmbH. Germany, 14–18 May.
  • Styriak, I., et al., 2001. The use of yeast for microbial degradation of some selected mycotoxins. Mycotoxin research, 17 (S1), 24–27.
  • Suzuki, Y., et al., 2008. Immunomodulation of bioactive gibberellin confers gibberellin-deficient phenotypes in plants. Plant biotechnology journal, 6 (4), 355–367.
  • Tedesco, D., et al., 2004. Efficacy of silymarin-phospholipid complex in reducing the toxicity of aflatoxin B1 in broiler chicks. Poultry science, 83 (11), 1839–1843.
  • Tejada-Castaneda, Z.I., et al., 2008. Biodetoxification of aflatoxin-contaminated chick feed. Poultry science, 87 (8), 1569–1576.
  • Teniola, O.D., et al., 2005. Degradation of aflatoxin B(1) by cell-free extracts of Rhodococcus erythropolis and Mycobacterium fluoranthenivorans sp. nov. DSM44556(T). International journal of food microbiology, 105 (2), 111–117.
  • Thirumala, K. D., et al., 2000. Recent advances in mycotoxin diagnosis. In: A. Chandrashekar, R. Bandyopadhayay, A. J. Hall, eds. Technical and institutional options for sorghum grain mold management: Proceedings of an international consultation. 18-19 May 2000, ICRISAT, Patancheru, India, Patancheru 502 324, Andhra Pradesh, India: International Crops Research Institute of Semi-Arid Tropics, 116–123.
  • Ueno, Y., et al., 1970. Comparative study on skin-necrotizing effect of scirpene metabolites of Fusaria. The Japanese journal of experimental medicine, 40 (1), 33.
  • Uhlinger, C., 1997. Leukoencephalomalacia. Veterinary clinics of North America: equine practice, 13 (1), 13–20.
  • Vanyi, A. and Szeky, A., 1980. Fusariotoxicoses. VII. Disturbed spermatogenesis caused by zearalenone (F-2 fuzriotoxin) and by imperfect illumination in guinea-cocks. Magyar – aallatorvosok lapja, 35, 247–252.
  • Vayias, B.J. and Stephons, V.K., 2009. Factors affecting the insecticidal efficacy of an enhanced diatomaceous earth formulation against three stored-product insect species. Journal of stored products research, 45 (4), 226–231.
  • Voss, K.A., et al., 1996. Subchronic toxic effects of Fusarium moniliforme and fumonisin B1 in rats and mice. Natural toxins, 4 (1), 16–23.
  • Voss, K.A., et al., 1998. In vivo effect of fumonisin B1-producing and fumonisin B1- nonproducing Fusarium moniliforme isolates are similar: fumonisin B2 and fumonisin B3 cause hepato- and nephrotoxicity in rats. Mycopathology, 141, 45–58
  • Wang, J., Fitzpatrick, D.W., and Wilson, J.R., 1998. Effects of the trichothecene mycotoxin T-2 toxin on neurotransmitters and metabolites in discrete areas of the rat brain. Food and Chemical Toxicology, 36 (11), 947–953.
  • Weaver, G.A., et al., 1978a. Effect of T-2 toxin on porcine reproduction. The Canadian veterinary journal, 19 (11), 310–314.
  • Weaver, G.A., et al., 1978b. Acute and chronic toxicity of T-2 mycotoxin in swine. Veterinary record, 103 (24), 531–535.
  • Weissinger, A., et al., 1999. Proc USDA-ARS Aflatoxin Elimination Workshop 66–68.
  • Williams, G.M., Tanaka, T., and Maeura, Y., 1986. Dose-related inhibition of aflatoxin B1 induced hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene. Carcinogenesis, 7 (7), 1043–1050.
  • Williams, G.M. and Iatropoulos, M.J., 1996. Inhibition of the hepatocarcinogenicity of aflatoxin B1 in rats by low levels of the phenolic antioxidants butylated hydroxyanisole and butylated hydroxytoluene. Cancer letters, 104 (1), 49–53.
  • Williams, K.C., Blaney, B.J., and Peters, R.T., 1994. Pigs fed Fusarium-infected maize containing zearalenone and nivalenol with sweeteners and bentonite. Livestock production science, 39 (3), 275–281.
  • Wilson, B.J. and Maronpot, P., 1971. Causative fungus agent of leucoencephalomalacia in equine animals. The veterinary record, 88 (19), 484–486.
  • Wiseman, D.W. and Marth, E.H., 1981. Growth and aflatoxin production by Aspergillus parasiticus when in the presence of Streptococcus lactis. Mycopathology, 73 (1), 49–56.
  • Wyatt, R.D., et al., 1972a. Possible outbreaks of fusariotoxicosis in avians. Avian diseases, 16 (5), 1123.
  • Wyatt, R.D., et al., 1972b. Severe oral lesions in chickens caused by ingestion of dietary fusariotoxin T-2. Applied microbiology, 24 (2), 251.
  • Wyss, G.S., 2005. Assessing the risk from mycotoxins for the organic food chain: organic food chain: results from organic HACCP (5th EU Results from Organic HACCP (5th EU-framework) and other framework) and other research, FiBL, viewed 7 July 2005. http://www.safonetwork.org/workshops/ws4/present/wyss2.pdf>
  • Yarru, L.P., et al., 2009. Effects of turmeric (Curcuma longa) on the expression of hepatic genes associated with biotransformation, antioxidant, and immune systems in broiler chicks fed aflatoxin. Poultry science, 88 (12), 2620–2627.
  • Yener, Z., et al., 2009. Effects of Urtica dioica L. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats. Food and chemical toxicology, 47 (2), 418–424.
  • Yenilmez, A., et al., 2010. Antioxidant effects of melatonin and coenzyme Q10 on oxidative damage caused by single-dose ochratoxin A in rat kidney. Chinese journal of physiology, 53 (5), 310–317.
  • Yiannikouris, A., et al., 2004. Comprehensive conformational study of key interactions involved in zearalenone complexation with β-d-glucan. Biomacromolecules, 5 (6), 2176–2185.
  • Zhang, M.Y., et al., 2008. Generation and evaluation of movement protein-specific single-chain antibodies for delaying symptoms of tomato spotted wilt virus infection in tobacco. Plant pathology, 57 (5), 854–860.
  • Zheng, J., et al., 2013. Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A. Toxicology and applied pharmacology, 268 (2), 123–131.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.