The research advances in the mechanism of manganese-induced neurotoxicity

References

• Anderson, J.G., Cooney, P.T., and Erikson, K.M., 2007. Brain manganese accumulation is inversely related to gamma-amino butyric acid uptake in male and female rats. Toxicological sciences, 95 (1), 188–195.
   Google Scholar
• Anderson, J.G., Fordahl, S.C., and Cooney, P.T., 2008. Manganese exposure alters extracellular GABA, GABA receptor and transporter protein and mRNA levels in the developing rat brain. Neurotoxicology, 29 (6), 1044–1053.
   Google Scholar
• Aschner, M., et al., 2009. Manganese and its role in Parkinson’s disease: from transport to neuropathology. Neuromolecular medicine, 11 (4), 252–266.
   Google Scholar
• Aschner, M., et al., 2007. Manganese: recent advances in understanding its transport and neurotoxicity. Toxicology and applied pharmacology, 221 (2), 131–147.
   Google Scholar
• Bahar, E., Kim, J.Y., and Yoon, H., 2017. Quercetin attenuates manganese-induced neuroinflammation by alleviating oxidative stress through regulation of apoptosis, iNOS/NF-κB and HO-1/Nrf2 pathways. International journal of molecular sciences, 18 (9), 1989.
   Google Scholar
• Bahar, E., et al., 2017. Polyphenolic extract of Euphorbia supina attenuates manganese-induced neurotoxicity by enhancing antioxidant activity through regulation of ER stress and ER stress-mediated apoptosis. International journal of molecular sciences, 18 (2), 300.
   Google Scholar
• Bałasz, M., et al., 2015. Perinatal manganese exposure and hydroxyl radical formation in rat brain. Neurotoxicity research, 27 (1), 1–14.
   Google Scholar
• Benedetto, A., Au, C., and Aschner, M., 2009. Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson’s disease. Chemical reviews, 109 (10), 4862–4884.
   Google Scholar
• Burton, N.C., et al., 2009. Effects of chronic manganese exposure on glutamatergic and gabaergic neurotransmitter markers in the nonhuman primate brain. Toxicological sciences, 111 (1), 131.
   Google Scholar
• Cai, S., L., et al., 2011. Case-control study on relationship between cyp2e1 polymorphisms and occupational susceptibility to chronic manganese exposure in Chinese Han population. Chinese journal of industrial medicine, (3):200–201.
   Google Scholar
• Chen, P., et al., 2015. Manganese homeostasis in the nervous system. Journal of neurochemistry, 134 (4), 601–610.
   Google Scholar
• Deng, Y., et al., 2008. Study on neurotoxincity mechanism induced by manganese chloride in rats. Chinese journal of industrial medicine, 21 (2), 103–105.
   Google Scholar
• de Rivero Vaccari, J.P., Dietrich, W.D., and Keane, R.W., 2014. Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. Journal of cerebral blood flow and metabolism: official journal of the international society of cerebral blood flow and metabolism, 34 (3), 369–375.
   Google Scholar
• Exil, V., et al., 2014. Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures. PLoS one, 9 (5), e94753.
   Google Scholar
• Fitsanakis, V.A., et al., 2006. The effects of manganese on glutamate, dopamine and γ-aminobutyric acid regulation. Neurochemistry international, 48 (6–7), 426–433.
   Google Scholar
• Galvani, P., Fumagalli, P., and Santagostino, A., 1995. Vulnerability of mitochondrial complex I in PC12 cells exposed to manganese. European journal of pharmacology, 293 (4), 377–383.
   Google Scholar
• Garcia, S.J., et al., 2007. Iron deficient and manganese supplemented diets alter metals and transporters in the developing rat brain. Toxicological sciences, 95 (1), 205–214.
   Google Scholar
• Gardner, B.M., et al., 2013. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harbor perspectives in biology, 5 (3), a013169.
   Google Scholar
• Guilarte, T.R., 2010. Manganese and Parkinson’s disease: a critical review and new findings. Environmental health perspectives, 118 (8), 1071–1080.
   Google Scholar
• Halperin, L., Jung, J., and Michalak, M., 2014. The many functions of the endoplasmic reticulum chaperones and folding enzymes. IUBMB Life, 66 (5), 318–326.
   Google Scholar
• Hamacher-Brady, A., 2012. Autophagy regulation and integration with cell signaling. Antioxidants & redox signaling, 17 (5), 756–765.
   Google Scholar
• Feng, H. and Feng, Y.U., 2010. Autophagy was involved in cytotoxicity of Mn(II) to SH-SY5Y cells. Journal of toxicology, 24 (6), 452–455.
   Google Scholar
• Jing, X., et al., 2015. Effect of vitamin E on the expression of hippocampus caspase-3 in manganese poisoned mice. Chinese journal of neuroanatomy, 31 (5), 635–638.
   Google Scholar
• Kaur, G., et al., 2017. Affected energy metabolism under manganese stress governs cellular toxicity. Scientific reports, 7 (1), 11645.
   Google Scholar
• Kirkley, K.S., et al., 2017. Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity. Journal of neuroinflammation, 14 (1), 99.
   Google Scholar
• Kwakye, G.F., et al., 2015. Manganese-induced Parkinsonism and Parkinson’s disease: shared and distinguishable features. International journal of environmental research and public health, 12 (7), 7519–7540.
   Google Scholar
• Lam, A.K. and Galione, A., 2013. The endoplasmic reticulum and junctional membrane communication during calcium signaling. Biochim biophys acta, 1833 (11), 2542–2559.
   Google Scholar
• Liu, W., et al., 2013. Hyperglycemia induces endoplasmic reticulum stress-dependent CHOP expression in osteoblasts. Experimental and therapeutic medicine, 5 (5), 1289–1292.
   Google Scholar
• Liu, X., et al., 2006. Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degeneration. Toxicological sciences, 91 (2), 521–531.
   Google Scholar
• Machado, V., et al., 2016. Microglia-mediated neuroinflammation and neurotrophic factor-induced protection in the MPTP mouse model of Parkinson’s disease-lessons from transgenic mice. International journal of molecular sciences, 17 (2), 151.
   Google Scholar
• Malthankar, G.V., et al., 2004. Differential lowering by manganese treatment of activities of glycolytic and tricarboxylic acid (TCA) cycle enzymes investigated in neuroblastoma and astrocytoma cells is associated with manganese-induced cell death. Neurochemical research, 29 (4), 709–717.
   Google Scholar
• Martinez-Finley, E.J., et al., 2013. Manganese neurotoxicity and the role of reactive oxygen species. Free radical biology and medicine, 62, 65–75.
   Google Scholar
• Mathieu, J., 2015. Interactions between autophagy and bacterial toxins: targets for therapy? Toxins, 7 (8), 2918–2958.
   Google Scholar
• Oakes, S.A. and Papa, F.R., 2015. The role of endoplasmic reticulum stress in human pathology. Annual review of pathology, 10, 173–194.
   Google Scholar
• O’Neal, S.L. and Zheng, W., 2015. Manganese toxicity upon overexposure: a decade in review. Current environmental health reports, 2 (3), 315.
   Google Scholar
• Peres, T.V., et al., 2013. In vitro manganese exposure disrupts MAPK signaling pathways in striatal and hippocampal slices from immature rats. BioMed research international, 2013 (339), 1.
   Google Scholar
• Roth, J.A., et al., 2013. The effect of manganese on dopamine toxicity and dopamine transporter (DAT) in control and DAT transfected HEK cells. Neurotoxicology, 35, 121–128.
   Google Scholar
• Santos, D., et al., 2012. The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain. Toxicology, 292 (2–3), 90–98.
   Google Scholar
• Schönthal, A.H., 2012. Endoplasmic reticulum stress: its role in disease and novel prospects for therapy. Scientifica, 2012 (4–6), 857516.
   Google Scholar
• Seo, Y.A., Li, Y., and Wessling-Resnick, M., 2013. Iron depletion increases manganese uptake and potentiates apoptosis through ER stress. Neurotoxicology, 38, 67–73.
   Google Scholar
• Sidoryk-Wegrzynowicz, M., 2014. Impairment of glutamine/glutamate-gamma-aminobutyric acid cycle in manganese toxicity in the central nervous system. Folia neuropathologica, 4 (4), 377–382.
   Google Scholar
• Sidoryk-Wegrzynowicz, M. and Aschner, M., 2013. Manganese toxicity in the central nervous system: the glutamine/glutamate-gamma-aminobutyric acid cycle. Journal of internal medicine, 273 (5), 466–477.
   Google Scholar
• Sriram, K., et al., 2015. Modifying welding process parameters can reduce the neurotoxic potential of manganese-containing welding fumes. Toxicology, 328, 168–178.
   Google Scholar
• Stanwood, G.D., et al., 2009. Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia. Journal of neurochemistry, 110 (1), 378–389.
   Google Scholar
• Streifel, K.M., et al., 2013. Manganese inhibits ATP-induced calcium entry through the transient receptor potential channel TRPC3 in astrocytes. Neurotoxicology, 34, 160–166.
   Google Scholar
• Struve, M.F., et al., 2007. Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation. American journal of industrial medicine, 50 (10), 772–778.
   Google Scholar
• Sun, X., et al., 2018. Neuritin attenuates neuronal apoptosis mediated by endoplasmic reticulum stress in vitro. Neurochemical research. doi: 10.1007/s11064-018-2553-4.
   Google Scholar
• Tuschl, K., Mills, P.B., and Clayton, P.T., 2013. Manganese and the brain. International review of neurobiology, 110, 277–312.
   Google Scholar
• Vaccari, J.P.D.R., Dietrich, W.D., and Keane, R.W., 2014. Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. Journal of cerebral blood flow and metabolism, 34 (3), 369–375.
   Google Scholar
• Wang, D., et al., 2017. The role of nlrp3-casp1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability. Autophagy, 13 (5), 1.
   Google Scholar
• Wang, T., et al., 2016. Pink1/parkin-mediated mitophagy play a protective role in manganese induced apoptosis in sh-sy5y cells. Toxicology in Vitro, 34, 212–219.
   Google Scholar
• Xie, W., et al., 2015. Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA. Autophagy, 11 (9), 1623–1635.
   Google Scholar
• Xuan, Y., et al., 2013. Involvement of the mitochondrion-dependent and the endoplasmic reticulum stress-signaling pathways in isoliquiritigenin-induced apoptosis of HeLa cell. Biomedical and environmental sciences, 26 (4), 268–276.
   Google Scholar
• Xu, Q., et al., 2011. Oxidative stress mechanism of manganese-treated PC12 cell line. Advances in modern biomedical research, 11 (3), 435–440.
   Google Scholar
• Xu, B., Xu, Z.F., and Deng, Y., 2010. Protective effects of MK-801 on manganese-induced glutamate metabolism disorder in rat striatum. Experimental and toxicologic pathology, 62 (4), 381–390.
   Google Scholar
• Zhang, H., et al., 2015. Mitochondrial autophagy mediated by PINK1/parkin in SH-SY5Y cells induced by MnCl2. China toxicology society: Hubei science and technology.
   Google Scholar
• Zhang, J., et al., 2013. The role of autophagy dysregulation in manganese-induced dopaminergic neurodegeneration. Neurotoxicity research, 24 (4), 478–490.
   Google Scholar
• Zhang, S., Fu, J., and Zhou, Z., 2004. In vitro effect of manganese chloride exposure on reactive oxygen species generation and respiratory chain complexes activities of mitochondria isolated from rat brain. Toxicology in vitro, 18 (1), 71–77.
   Google Scholar
• Zhang, S.J., et al., 2016. Autophagy: a double-edged sword in intervertebral disk degeneration. Clinica chimica acta: international journal of clinical chemistry, 457, 27–35.
   Google Scholar
• Zhao, S., et al., 2017. Study on emission of hazardous trace elements in a 350 MW coal-fired power plant. Part 1. Mercury Environmental pollution, 229, 863–870.
   Google Scholar