Air pollution-induced placental epigenetic alterations in early life: a candidate miRNA approach

References

• Pope CA, Dockery DW. Health effects of fine particulate air pollution: Lines that connect. J Air Waste Manage Assoc. 2006;56:709–742. doi:10.1080/10473289.2006.10464485. PMID:16805397
   PubMed Web of Science ®Google Scholar
• Yang W, Omaye ST. Air pollutants, oxidative stress and human health. Mutat Res. 2009;674:45–54. doi:10.1016/j.mrgentox.2008.10.005. PMID:19013537
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Kim C, Devlin RB. Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers. Am J Respir Crit Care Med. 2000;162:981–988. doi:10.1164/ajrccm.162.3.9911115. PMID:10988117
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Huang Y-CT. Exposure to concentrated ambient particles (CAPs): A review. Inhal Toxicol. 2004;16:53–59. doi:10.1080/08958370490258390. PMID:14744665
   PubMed Web of Science ®Google Scholar
• Brook RD, Rajagopalan S, Pope CA, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American heart association. Circulation. 2010;121:2331–2378. doi:10.1161/CIR.0b013e3181dbece1. PMID:20458016
   PubMed Web of Science ®Google Scholar
• Malmström K, Pelkonen AS, Malmberg LP, et al. Lung function, airway remodelling and inflammation in symptomatic infants: outcome at 3 years. Thorax. 2011;66:157–162. doi:10.1136/thx.2010.139246. PMID:21199817
   PubMed Web of Science ®Google Scholar
• Blomberg A, Krishna MT, Bocchino V, et al. The inflammatory effects of 2 ppm NO2 on the airways of healthy subjects. Am J Respir Crit Care Med. 1997;156:418–424. doi:10.1164/ajrccm.156.2.9612042. PMID:9279218
   PubMed Web of Science ®Google Scholar
• Barker DJP. Developmental origins of adult health and disease. J Epidemiol Commun Health. 2004;58:114–115. doi:10.1136/jech.58.2.114. PMID:14729887
   PubMed Web of Science ®Google Scholar
• Alastalo H, von Bonsdorff MB, Räikkönen K, et al. Early life stress and physical and psychosocial functioning in late adulthood. PLoS ONE. 2013;8:e69011. doi:10.1371/journal.pone.0069011. PMID:23861956
   PubMed Web of Science ®Google Scholar
• Pedersen M, Giorgis-Allemand L, Bernard C, et al. Ambient air pollution and low birthweight: a European cohort study (ESCAPE). Lancet Resp Med. 2013;1:695–704. doi:10.1016/S2213-2600(13)70192-9. PMID:24429273
   PubMed Web of Science ®Google Scholar
• Rappazzo KM, Daniels DL, Messer LC, et al. Exposure to fine particulate matter during pregnancy and risk of preterm birth among women in New Jersey, Ohio, and Pennsylvania, 2000–2005. Environ Health Perspect. 2014;122:992–997. doi:10.1289/ehp.1307456. PMID:24879653
   PubMed Web of Science ®Google Scholar
• van den Hooven EH, Pierik FH, de Kluizenaar Y, et al. Air pollution exposure and markers of placental growth and function: The generation R study. Environ Health Perspect. 2012;120:1753–1759. PMID:22922820
   PubMed Web of Science ®Google Scholar
• Veras MM, Damaceno-Rodrigues NR, Caldini EG, et al. Particulate Urban air pollution affects the functional morphology of mouse placenta. Bio Reprod. 2008;79:578–584. doi:10.1095/biolreprod.108.069591. PMID:18509159
   PubMed Web of Science ®Google Scholar
• Saenen ND, Plusquin M, Bijnens E, et al. In Utero fine particle air pollution and placental expression of genes in the brain-derived Neurotrophic factor signaling pathway: An ENVIRONAGE birth cohort study. Environ Health Perspect. 2015. doi:10.1289/ehp.1408549.PMID:25816123
   PubMed Web of Science ®Google Scholar
• de Melo JO, Soto SF, Katayama IA, et al. Inhalation of fine particulate matter during pregnancy increased IL-4 cytokine levels in the fetal portion of the placenta. Toxicol Lett. 2015;232:475–480. doi:10.1016/j.toxlet.2014.12.001. PMID:25481569
   PubMed Web of Science ®Google Scholar
• Jansson T, Powell T. Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches. Clin Sci. 2007;113:1–13. doi:10.1042/CS20060339. PMID:17536998.
   PubMed Web of Science ®Google Scholar
• Etheridge A, Lee I, Hood L, et al. Extracellular microRNA: A new source of biomarkers. Mutat Res. 2011;717:85–90. doi:10.1016/j.mrfmmm.2011.03.004.
   PubMed Web of Science ®Google Scholar
• Ambros V. The functions of animal microRNAs. Nature. 2004;431:350–355. doi:10.1038/nature02871. PMID:15372042
   PubMed Web of Science ®Google Scholar
• Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell. 2004;116:281–297. doi:10.1016/S0092-8674(04)00045-5. PMID:14744438
   PubMed Web of Science ®Google Scholar
• Wang Y, Lee CGL. MicroRNA and cancer – focus on apoptosis. J Cell Mol Med. 2009;13:12–23. doi:10.1111/j.1582-4934.2008.00510.x. PMID:19175697
   PubMed Web of Science ®Google Scholar
• Lu M, Zhang Q, Deng M, et al. An analysis of human MicroRNA and disease associations. PLoS ONE. 2008;3:e3420. doi:10.1371/journal.pone.0003420. PMID:18923704
   PubMed Web of Science ®Google Scholar
• Felekkis K, Touvana E, Stefanou C, et al. microRNAs: a newly described class of encoded molecules that play a role in health and disease. Hippokratia. 2010;14:236–240. PMID:21311629
   PubMed Web of Science ®Google Scholar
• Wilczynska A, Bushell M. The complexity of miRNA-mediated repression. Cell Death Differ. 2015;22:22–33. doi:10.1038/cdd.2014.112. PMID:25190144
   PubMed Web of Science ®Google Scholar
• Fossati S, Baccarelli A, Zanobetti A, et al. Ambient particulate air pollution and microRNAs in elderly men. Epidemiology. 2014;25:68–78. doi:10.1097/EDE.0000000000000026. PMID:24257509
   PubMed Web of Science ®Google Scholar
• Bollati V, Marinelli B, Apostoli P, et al. Exposure to metal-rich particulate matter modifies the expression of candidate Micrornas in peripheral blood leukocytes. Environ Health Perspect. 2010;118:763–768. doi:10.1289/ehp.0901300. PMID:20061215
   PubMed Web of Science ®Google Scholar
• Fry RC, Rager JE, Bauer R, et al. Air toxics and epigenetic effects: ozone altered microRNAs in the sputum of human subjects. Am J Physiol Lung Cell Mol Physiol 2014;306:L1129–L1137. doi:10.1152/ajplung.00348.2013. PMID:24771714
   PubMed Web of Science ®Google Scholar
• Avissar-Whiting M, Veiga K, Uhl K, et al. Bisphenol a exposure leads to specific MicroRNA alterations in placental cells. Reprod Toxicol. 2010;29:401–406. doi:10.1016/j.reprotox.2010.04.004. PMID:20417706
   PubMed Web of Science ®Google Scholar
• Herberth G, Bauer M, Gasch M, et al. Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers. J Allergy Clinical Immunol. 2014;133:543–550.e4. doi:10.1016/j.jaci.2013.06.036. PMID:23978443
   PubMed Web of Science ®Google Scholar
• Maccani MA, Avissar-Whiting M, Banister CE, et al. Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta. Epigenetics. 2010;5:583–589. doi:10.4161/epi.5.7.12762. PMID:20647767
   PubMed Web of Science ®Google Scholar
• Rudov A, Balduini W, Carloni S, et al. Involvement of miRNAs in placental alterations mediated by oxidative stress. Oxid Med Cell Longev. 2014;2014:7. doi:10.1155/2014/103068.
   Google Scholar
• Vrijens K, Bollati V, Nawrot TS. MicroRNAs as potential signatures of environmental exposure or effect: A systematic review. Environ Health Perspect. 2015;123:399–411. doi:10.1289/ehp.1408459. PMID:25616258
   PubMed Web of Science ®Google Scholar
• Zhou X, Ren Y, Moore L, et al. Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Invest. 2010;90:144–155. doi:10.1038/labinvest.2009.126. PMID:20048743
   PubMed Web of Science ®Google Scholar
• Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Nat Acad Sci U S A. 2005;102:13944–13949. doi:10.1073/pnas.0506654102. PMID:16166262
   PubMed Web of Science ®Google Scholar
• Rivas MA, Venturutti L, Huang Y-W, et al. Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. Breast Cancer Res: BCR. 2012;14:R77–R. doi:10.1186/bcr3187. PMID:22583478
   PubMed Web of Science ®Google Scholar
• Yang Y, Meng H, Peng Q, et al. Downregulation of microRNA-21 expression restrains non-small cell lung cancer cell proliferation and migration through upregulation of programmed cell death 4. Cancer Gene Ther. 2015;22:23–29. doi:10.1038/cgt.2014.66. PMID:25477028
   PubMed Web of Science ®Google Scholar
• Ke Y, Zhao W, Xiong J, et al. Downregulation of miR-16 promotes growth and motility by targeting HDGF in non-small cell lung cancer cells. FEBS Lett. 2013;587:3153–3157. doi:10.1016/j.febslet.2013.08.010. PMID:23954293
   PubMed Web of Science ®Google Scholar
• Maccani MA, Padbury JF, Marsit CJ. miR-16 and miR-21 Expression in the placenta is associated with fetal growth. PLoS ONE. 2011;6:e21210. doi:10.1371/journal.pone.0021210. PMID:21698265
   PubMed Web of Science ®Google Scholar
• Baldeón RL, Weigelt K, de Wit H, et al. Decreased serum level of miR-146a as sign of chronic inflammation in Type 2 diabetic patients. PLoS ONE. 2014;9:e115209. doi:10.1371/journal.pone.0115209. PMID:25500583
   PubMed Web of Science ®Google Scholar
• Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res. 2008;79:581–588. doi:10.1093/cvr/cvn156. PMID:18550634
   PubMed Web of Science ®Google Scholar
• Wang W, Feng L, Zhang H, et al. Preeclampsia Up-regulates angiogenesis-associated MicroRNA (i.e., miR-17, -20a, and -20b) that target Ephrin-B2 and EPHB4 in human placenta. J Clinical Endocrinol Metab. 2012;97:E1051–E9. doi:10.1210/jc.2011-3131. PMID:22438230
   PubMed Web of Science ®Google Scholar
• Umemura K, Ishioka S-i, Endo T, et al. Roles of microRNA-34a in the pathogenesis of placenta accreta. J Obstet Gynaecol Res. 2013;39:67–74. doi:10.1111/j.1447-0756.2012.01898.x. PMID:22672425
   PubMed Web of Science ®Google Scholar
• Zhao T, Li J, Chen AF. MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1. Am J Physiol Endocrinol Metab. 2010;299:E110–E116. doi:10.1152/ajpendo.00192.2010. PMID:20424141
   PubMed Web of Science ®Google Scholar
• Farraj AK, Hazari MS, Haykal-Coates N, et al. ST Depression, arrhythmia, vagal dominance, and reduced cardiac Micro-RNA in particulate-exposed rats. Am J Respir Cell Mol Biol. 2011;44:185–196. doi:10.1165/rcmb.2009-0456OC. PMID:20378750
   PubMed Web of Science ®Google Scholar
• Motta V, Angelici L, Nordio F, et al. Integrative analysis of miRNA and inflammatory gene expression after acute particulate matter exposure. Toxicol Sci. 2013;132:307–316. doi:10.1093/toxsci/kft013. PMID:23358196
   PubMed Web of Science ®Google Scholar
• Pineles BL, Romero R, Montenegro D, et al. Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia. Am J Obstet Gynecol. 2007;196:261.e1–261.e6. doi:10.1016/j.ajog.2007.01.008.
   PubMed Web of Science ®Google Scholar
• Li Q, Kappil MA, Li A, et al. Exploring the associations between microRNA expression profiles and environmental pollutants in human placenta from the National Children's Study (NCS). Epigenetics. 2015;10:793–802. doi:10.1080/15592294.2015.1066960. PMID:26252056
   PubMed Web of Science ®Google Scholar
• Jirtle RL, Skinner MK. Environmental epigenomics and disease susceptibility. Nat Rev Genet. 2007;8:253–62. doi:10.1038/nrg2045. PMID:17363974
   PubMed Web of Science ®Google Scholar
• Janssen BG, Godderis L, Pieters N, et al. Placental DNA hypomethylation in association with particulate air pollution in early life. Part Fibre Toxicol. 2013;10:22-. doi:10.1186/1743-8977-10-22. PMID:23742113
   PubMed Web of Science ®Google Scholar
• Sathyan P, Golden HB, Miranda RC. Competing Interactions between Micro-RNAs Determine neural progenitor survival and proliferation after ethanol exposure: evidence from an Ex Vivo model of the fetal cerebral cortical neuroepithelium. J Neurosci. 2007;27:8546–8557. doi:10.1523/JNEUROSCI.1269-07.2007. PMID:17687032
   PubMed Web of Science ®Google Scholar
• Tal TL, Franzosa JA, Tilton SC, et al. MicroRNAs control neurobehavioral development and function in zebrafish. FASEB J. 2012;26:1452–1461. doi:10.1096/fj.11-194464. PMID:22253472
   PubMed Web of Science ®Google Scholar
• Wang L-L, Zhang Z, Li Q, et al. Ethanol exposure induces differential microRNA and target gene expression and teratogenic effects which can be suppressed by folic acid supplementation. Human Reprod. 2009;24:562–579. doi:10.1093/humrep/den439. PMID:19091803
   PubMed Web of Science ®Google Scholar
• Pietrzykowski AZ, Friesen RM, Martin GE, et al. Post-transcriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcohol. Neuron. 2008;59:274–287. doi:10.1016/j.neuron.2008.05.032. PMID:18667155
   PubMed Web of Science ®Google Scholar
• Costantine M. Physiologic and pharmacokinetic changes in pregnancy. Front Pharmacol. 2014;5. doi:10.3389/fphar.2014.00065. PMID:24772083
   PubMed Web of Science ®Google Scholar
• Lassmann T, Maida Y, Tomaru Y, et al. Telomerase Reverse Transcriptase Regulates microRNAs. Int J Mol Sci. 2015;16:1192–1208. doi:10.3390/ijms16011192. PMID:25569094
   PubMed Web of Science ®Google Scholar
• Colgin LM, Reddel RR. Telomere maintenance mechanisms and cellular immortalization. Curr Opin Genet Dev. 1999;9:97–103. doi:10.1016/S0959-437X(99)80014-8.
   PubMed Web of Science ®Google Scholar
• Bijnens E, Zeegers MP, Gielen M, et al. Lower placental telomere length may be attributed to maternal residential traffic exposure; a twin study. Environ Int. 2015;79:1–7. doi:10.1016/j.envint.2015.02.008. PMID:25756235
   PubMed Web of Science ®Google Scholar
• Kitagishi Y, Matsuda, S. Redox regulation of tumor suppressor PTEN in cancer and aging. Int J Mol Med. 2013;31:511–515. doi:10.3892/ijmm.2013.1235. PMID:23313933
   PubMed Web of Science ®Google Scholar
• Kuhn DE, Martin MM, Feldman DS, et al. Experimental validation of miRNA targets. Methods. 2008;44:47–54. doi:10.1016/j.ymeth.2007.09.005. PMID:18158132
   PubMed Web of Science ®Google Scholar
• Tokyol C, Aktepe F, Dilek FH, et al. Comparison of Placental PTEN and β1 integrin expression in early spontaneous abortion, early and late normal pregnancy. Ups J Med Sci. 2008;113:235–242. doi:10.3109/2000-1967-231. PMID:18509818
   PubMed Web of Science ®Google Scholar
• Li L, Kang J, Lei W. Role of Toll-like receptor 4 in inflammation-induced preterm delivery. Mol Human Reprod. 2010;16:267–272. doi:10.1093/molehr/gap106. PMID:19995880
   PubMed Web of Science ®Google Scholar
• Vaughan JE, Walsh SW. Activation of NF-κB in Placentas of Women with Preeclampsia. Hypertens Pregnancy. 2012;31:243–251. doi:10.3109/10641955.2011.642436.
   PubMed Web of Science ®Google Scholar
• Choi H-K, Choi BC, Lee S-H, et al. Expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients. Mol Reprod Dev. 2003;66:24–31. doi:10.1002/mrd.10331. PMID:12874795
   PubMed Web of Science ®Google Scholar
• Reynolds LP, Redmer RD. Utero-placental vascular development and placental function. J Anim Sci. 1995;73:1839–1851. doi:10.2527/1995.7361839x. PMID:7545661
   PubMed Web of Science ®Google Scholar
• Winn VD, Haimov-Kochman R, Paquet AC, et al. Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term. Endocrinology. 2007;148:1059–1079. doi:10.1210/en.2006-0683. PMID:17170095
   PubMed Web of Science ®Google Scholar
• Bind M-A, Zanobetti A, Gasparrini A, et al. Effects of temperature and relative humidity on DNA methylation. Epidemiology. 2014;25:561–569. doi:10.1097/EDE.0000000000000120. PMID:24809956
   PubMed Web of Science ®Google Scholar
• Cox B, Martens E, Nemery B, et al. Impact of a stepwise introduction of smoke-free legislation on the rate of preterm births: analysis of routinely collected birth data. BMJ. 2013;346:f441. doi:10.1136/bmj.f441.
   Google Scholar
• Janssen BG, Byun H-M, Gyselaers W, et al. Placental mitochondrial methylation and exposure to airborne particulate matter in the early life environment: An ENVIRONAGE birth cohort study. Epigenetics. 2015;10:536–544. doi:10.1080/15592294.2015.1048412. PMID:25996590
   PubMed Web of Science ®Google Scholar
• Lefebvre W, Degrawe B, Beckx C, et al. Presentation and evaluation of an integrated model chain to respond to traffic- and health-related policy questions. Environ Modell Software. 2013;40:160–170. doi:10.1016/j.envsoft.2012.09.003.
   Web of Science ®Google Scholar
• Lefebvre W, Vercauteren J, Schrooten L, et al. Validation of the MIMOSA-AURORA-IFDM model chain for policy support: Modeling concentrations of elemental carbon in Flanders. Atmos Environ. 2011;45:6705–6713. doi:10.1016/j.atmosenv.2011.08.033.
   Web of Science ®Google Scholar
• Maiheu B VB, Viaene P, De Ridde rK, et al. Identifying the best available large-scale concentration maps for air quality in Belgium. Mol, Belgium: Flemish Institute for Technological Research (VITO); 2013.
   Google Scholar
• Hsu S-D, Tseng Y-T, Shrestha S, et al. miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions. Nucleic Acids Res. 2014;42:D78–D85. doi:10.1093/nar/gkt1266. PMID:24304892
   PubMed Web of Science ®Google Scholar
• Vlachos IS, Kostoulas N, Vergoulis T, et al. DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res. 2012;40:W498–W504. doi:10.1093/nar/gks494. PMID:22649059
   PubMed Web of Science ®Google Scholar
• Vlachos IS, Paraskevopoulou MD, Karagkouni D, et al. DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions. Nucleic Acids Res. 2014. doi:10.1093/nar/gku1215. PMID:25416803
   PubMed Web of Science ®Google Scholar
• Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Royal Stat Soc Series B. 1995;57:289–300.
   Web of Science ®Google Scholar