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Epigenetics Volume 11, 2016 - Issue 9
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Brief Report

The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons

Kevin A. HopeDepartments of Neurology, Anatomy and Neurobiology, The University of Tennessee Health Science Center, Memphis, TN, USA
,
Mark S. LeDouxDepartments of Neurology, Anatomy and Neurobiology, The University of Tennessee Health Science Center, Memphis, TN, USA
&
Lawrence T. ReiterDepartments of Neurology, Anatomy and Neurobiology, The University of Tennessee Health Science Center, Memphis, TN, USA;Pediatrics, The University of Tennessee Health Science Center, Memphis, TN, USACorrespondence[email protected]
, Ph.D.
Pages 637-642 | Received 03 Jun 2016, Accepted 14 Jul 2016, Published online: 08 Sep 2016

References

  • Kishino T, Lalande M Wagstaff J. UBE3A/E6-AP mutations cause Angelman syndrome. Nat Genet 1997; 15:70-3; PMID:8988171; http://dx.doi.org/10.1038/ng0197-70
  • LaSalle JM, Reiter LT, Chamberlain SJ. Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders. Epigenomics 2015; 7:1213-28; PMID:26585570; http://dx.doi.org/10.2217/epi.15.70
  • Knoll JH, Nicholls RD, Magenis RE, Graham JM Jr, Lalande M, Latt SA. Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion. Am J Med Genet 1989; 32:285-90; PMID:2564739; http://dx.doi.org/10.1002/ajmg.1320320235
  • Rougeulle C, Glatt H, Lalande M. The Angelman syndrome candidate gene, UBE3A/E6-AP, is imprinted in brain. Nat Genet 1997; 17:14-15; PMID:9288088; http://dx.doi.org/10.1038/ng0997-14
  • Albrecht U, Sutcliffe JS, Cattanach BM, Beechey CV, Armstrong D, Eichele G, Beaudet AL. Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons. Nat Genet. 1997 Sep; 17(1):75-8; PMID:9288101
  • Dindot SV, Antalffy BA, Bhattacharjee MB, Beaudet AL. The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum Mol Genet 2008; 17:111-8; PMID:17940072; http://dx.doi.org/10.1093/hmg/ddm288
  • Judson MC, Sosa-Pagan JO, Del Cid WA, Han JE, Philpot BD. Allelic specificity of Ube3a expression in the mouse brain during postnatal development. J Comp Neurol 2014; 522:1874-96; PMID:24254964; http://dx.doi.org/10.1002/cne.23507
  • Chamberlain SJ, Chen PF, Ng KY, Bourgois-Rocha F, Lemtiri-Chlieh F, Levine ES, Lalande M. Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes. Proc Natl Acad Sci U S A 2010; 107:17668-73; PMID:20876107; http://dx.doi.org/10.1073/pnas.1004487107
  • Yamasaki K, Joh K, Ohta T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Ogawa M, Wagstaff J, Kishino T. Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a. Hum Mol Genet 2003; 12:837-47; PMID:12668607; http://dx.doi.org/10.1093/hmg/ddg106
  • Kelsey G, Feil R. New insights into establishment and maintenance of DNA methylation imprints in mammals. Philos Trans R Soc Lond B Biol Sci 2013; 368:20110336; PMID:23166397; http://dx.doi.org/10.1098/rstb.2011.0336
  • Reiter LT, Seagroves TN, Bowers M, Bier E. Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase. Hum Mol Genet 2006; 15:2825-35; PMID:16905559; http://dx.doi.org/10.1093/hmg/ddl225
  • Wu Y, Bolduc FV, Bell K, Tully T, Fang Y, Sehgal A, Fischer JA. A Drosophila model for Angelman syndrome. Proc Natl Acad Sci U S A 2008; 105:12399-404; PMID:18701717; http://dx.doi.org/10.1073/pnas.0805291105
  • Chakraborty M, Paul BK, Nayak T, Das A, Jana NR, Bhutani S. The E3 ligase ube3a is required for learning in Drosophila melanogaster. Biochem Biophys Res Commun 2015; 462:71-7; PMID:25935478; http://dx.doi.org/10.1016/j.bbrc.2015.04.110
  • Valdez C, Scroggs R, Chassen R, Reiter LT. Variation in Dube3a expression affects neurotransmission at the Drosophila neuromuscular junction. Biol Open 2015; 4:776-82; PMID:25948754; http://dx.doi.org/10.1242/bio.20148045
  • Ugur B, Chen K, Bellen HJ. Drosophila tools and assays for the study of human diseases. Dis Model Mech 2016; 9:235-44; PMID:26935102; http://dx.doi.org/10.1242/dmm.023762
  • Mackay TF, Richards S, Stone EA, Barbadilla A, Ayroles JF, Zhu D, Casillas S, Han Y, Magwire MM, Cridland JM, et al. The drosophila melanogaster genetic reference panel. Nature 2012; 482:173-8; PMID:22318601; http://dx.doi.org/10.1038/nature10811
  • Desai-Shah M, Cooper RL. Different mechanisms of Ca2+ regulation that influence synaptic transmission: comparison between crayfish and Drosophila neuromuscular junctions. Synapse 2009; 63:1100-21; PMID:19650116; http://dx.doi.org/10.1002/syn.20695
  • Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D. The human genome browser at UCSC. Genome Res 2002; 12:996-1006. Article published online before print in May 2002 ; PMID:12045153; http://dx.doi.org/10.1101/gr.229102.
  • Hatfield I, Harvey I, Yates ER, Redd JR, Reiter LT, Bridges D. The role of TORC1 in muscle development in Drosophila. Sci Rep 2015; 5:9676; PMID:25866192; http://dx.doi.org/10.1038/srep09676
  • Vilinsky I, Johnson KG. Electroretinograms in Drosophila: a robust and genetically accessible electrophysiological system for the undergraduate laboratory. J Undergrad Neurosci Educ 2012; 11:A149-57; PMID:23494679

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