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Research Paper

Familial resemblances in blood leukocyte DNA methylation levels

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Pages 831-838 | Received 13 Jul 2016, Accepted 30 Aug 2016, Published online: 01 Nov 2016

References

  • Waterland RA. Epigenetic mechanisms and gastrointestinal development. J Pediatrics 2006; 149:S137-42; PMID:17212956; http://dx.doi.org/10.1016/j.jpeds.2006.06.064
  • Feinberg AP. Epigenetics at the epicenter of modern medicine. JAMA 2008; 299:1345-50; PMID:18349095; http://dx.doi.org/10.1001/jama.299.11.1345
  • Daxinger L, Whitelaw E. Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nat Rev Genetics 2012; 13:153-62; PMID:22290458; http://dx.doi.org/10.1038/nrm3288
  • Friso S, Pizzolo F, Choi SW, Guarini P, Castagna A, Ravagnani V, Carletto A, Pattini P, Corrocher R, Olivieri O. Epigenetic control of 11 β-hydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension. Atherosclerosis 2008; 199:323-7; PMID:18178212; http://dx.doi.org/10.1016/j.atherosclerosis.2007.11.029
  • Turunen MP, Aavik E, Yla-Herttuala S. Epigenetics and atherosclerosis. Biochimica Et Biophys Acta 2009; 1790:886-91; PMID:19233248; http://dx.doi.org/10.1016/j.bbagen.2009.02.008
  • Makar KW, Wilson CB. DNA methylation is a nonredundant repressor of the Th2 effector program. J Immunol 2004; 173:4402-6; PMID:15383570; http://dx.doi.org/10.4049/jimmunol.173.7.4402
  • Pembrey ME, Bygren LO, Kaati G, Edvinsson S, Northstone K, Sjostrom M, Golding J, Team AS. Sex-specific, male-line transgenerational responses in humans. Eur J Hum Genetics 2006; 14:159-66; PMID:16391557; http://dx.doi.org/10.1038/sj.ejhg.5201538
  • Shoemaker R, Deng J, Wang W, Zhang K. Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. Genome Res 2010; 20:883-9; PMID:20418490; http://dx.doi.org/10.1101/gr.104695.109
  • McRae AF, Powell JE, Henders AK, Bowdler L, Hemani G, Shah S, Painter JN, Martin NG, Visscher PM, Montgomery GW. Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biol 2014; 15:R73; PMID:24887635; http://dx.doi.org/10.1186/gb-2014-15-5-r73
  • Guibert S, Forne T, Weber M. Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res 2012; 22:633-41; PMID:22357612; http://dx.doi.org/10.1101/gr.130997.111
  • Roseboom TJ, van der Meulen JH, Osmond C, Barker DJ, Ravelli AC, Schroeder-Tanka JM, van Montfrans GA, Michels RP, Bleker OP. Coronary heart disease after prenatal exposure to the Dutch famine, 1944–45. Heart 2000; 84:595-8; PMID:11083734; http://dx.doi.org/10.1136/heart.84.6.595
  • Kaati G, Bygren LO, Pembrey M, Sjostrom M. Transgenerational response to nutrition, early life circumstances and longevity. European J Hum Genetics 2007; 15:784-90; PMID:17457370; http://dx.doi.org/10.1038/sj.ejhg.5201832
  • Bell JT, Spector TD. DNA methylation studies using twins: what are they telling us? Genome Biol 2012; 13:172; PMID:23078798; http://dx.doi.org/10.1186/gb-2012-13-10-172
  • Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G, Zhang F, Valdes A, et al. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genetics 2012; 8:e1002629; PMID:22532803; http://dx.doi.org/10.1371/journal.pgen.1002629
  • Gordon L, Joo JE, Powell JE, Ollikainen M, Novakovic B, Li X, Andronikos R, Cruickshank MN, Conneely KN, Smith AK, et al. Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res 2012; 22:1395-406; PMID:22800725; http://dx.doi.org/10.1101/gr.136598.111
  • Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, Busche S, Yuan W, Nisbet J, Sekowska M, et al. Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genetics 2013; 93:876-90; PMID:24183450; http://dx.doi.org/10.1016/j.ajhg.2013.10.004
  • Gibbs JR, van der Brug MP, Hernandez DG, Traynor BJ, Nalls MA, Lai SL, Arepalli S, Dillman A, Rafferty IP, Troncoso J, et al. Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genetics 2010; 6:e1000952; PMID:20485568; http://dx.doi.org/10.1371/journal.pgen.1000952
  • Drong AW, Nicholson G, Hedman AK, Meduri E, Grundberg E, Small KS, Shin SY, Bell JT, Karpe F, Soranzo N, et al. The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue. PloS One 2013; 8:e55923; PMID:23431366; http://dx.doi.org/10.1371/journal.pone.0055923
  • Trowsdale J, Knight JC. Major histocompatibility complex genomics and human disease. Ann Rev Genomics Hum Genetics 2013; 14:301-23; PMID:23875801; http://dx.doi.org/10.1146/annurev-genom-091212-153455
  • Gervin K, Hammero M, Akselsen HE, Moe R, Nygard H, Brandt I, Gjessing HK, Harris JR, Undlien DE, Lyle R. Extensive variation and low heritability of DNA methylation identified in a twin study. Genome Res 2011; 21:1813-21; PMID:21948560; http://dx.doi.org/10.1101/gr.119685.110
  • Weissglas-Volkov D, Pajukanta P. Genetic causes of high and low serum HDL-cholesterol. J Lipid Res 2010; 51:2032-57; PMID:20421590; http://dx.doi.org/10.1194/jlr.R004739
  • Qasim A, Rader DJ. Human genetics of variation in high-density lipoprotein cholesterol. Curr Atherosclerosis Reports 2006; 8:198-205; PMID:16767843; http://dx.doi.org/10.1007/s11883-006-0074-0
  • Lusis AJ, Mar R, Pajukanta P. Genetics of atherosclerosis. Ann Rev Genomics Hum Genetics 2004; 5:189-218; PMID:15485348; http://dx.doi.org/10.1146/annurev.genom.5.061903.175930
  • Bosse Y, Vohl MC, Despres JP, Lamarche B, Rice T, Rao DC, Bouchard C, Perusse L. Heritability of LDL peak particle diameter in the Quebec Family Study. Genetic Epidemiol 2003; 25:375-81; PMID:14639707; http://dx.doi.org/10.1002/gepi.10272
  • Traherne JA. Human MHC architecture and evolution: implications for disease association studies. Int J Immunogenetics 2008; 35:179-92; PMID:18397301; http://dx.doi.org/10.1111/j.1744-313X.2008.00765.x
  • Lemire M, Zaidi SH, Ban M, Ge B, Aissi D, Germain M, Kassam I, Wang M, Zanke BW, Gagnon F, et al. Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci. Nat Commun 2015; 6:6326; PMID:25716334; http://dx.doi.org/10.1038/ncomms7326
  • Genomes Project C, Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, Kang HM, Marth GT, McVean GA. An integrated map of genetic variation from 1,092 human genomes. Nature 2012; 491:56-65; PMID:23128226; http://dx.doi.org/10.1038/nature11632
  • Byun HM, Siegmund KD, Pan F, Weisenberger DJ, Kanel G, Laird PW, Yang AS. Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genetics 2009; 18:4808-17; PMID:19776032; http://dx.doi.org/10.1093/hmg/ddp445
  • Fan S, Zhang X. CpG island methylation pattern in different human tissues and its correlation with gene expression. Biochem Biophys Res Commun 2009; 383:421-5; PMID:19364493; http://dx.doi.org/10.1016/j.bbrc.2009.04.023
  • Callaway C, Chumlea W, Bouchard C, Himes J, Lohman T, Martin A, Mitchell C, Mueller W, Roche A, Seefeldt V. Standardization of anthropomeric measurements : The Airlie (VA) Consensus Conference. In: TG. L, AF. R, R. M, eds. Champaign, IR, USA, 1988:39-80
  • Price ME, Cotton AM, Lam LL, Farre P, Emberly E, Brown CJ, Robinson WP, Kobor MS. Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array. Epigenetics Chromatin 2013; 6:4; PMID:23452981; http://dx.doi.org/10.1186/1756-8935-6-4
  • Team RC. R: A language and environment for statistical computing. R Foundation for Statistical Computing. Vienna, Austria, 2013
  • Abecasis GR, Cardon LR, Cookson WO. A general test of association for quantitative traits in nuclear families. Am J Hum Genetics 2000; 66:279-92; PMID:10631157; http://dx.doi.org/10.1086/302698
  • Zhang H, Meltzer P, Davis S. RCircos: an R package for Circos 2D track plots. BMC Bioinformatics 2013; 14:244; PMID:23937229; http://dx.doi.org/10.1186/1471-2105-14-244

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