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Research Paper

Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease

, , ORCID Icon, &
Pages 1150-1167 | Received 13 Jul 2020, Accepted 23 Oct 2020, Published online: 09 Dec 2020

References

  • Nilsson E, Sadler-Riggleman I, Skinner MK. Environmentally induced epigenetic transgenerational inheritance of disease. Environ Epigenet. 2018;4(2):1–13.
  • Soubry A. Epigenetic inheritance and evolution: a paternal perspective on dietary influences. Prog Biophys Mol Biol. 2015;118(1–2):79–85.
  • Vaiserman AM, Koliada AK, Jirtle RL. Non-genomic transmission of longevity between generations: potential mechanisms and evidence across species. Epigenetics Chromatin. 2017;10(1):38.
  • Legoff L, D’Cruz SC, Tevosian S, et al. Transgenerational inheritance of environmentally induced epigenetic alterations during mammalian development. Cells. 2019;8(12):1559.
  • Waterland RA. Epigenetic mechanisms and gastrointestinal development. J Pediatr. 2006;149(5 Suppl):S137–42.
  • Skinner MK, Guerrero-Bosagna C. Environmental signals and transgenerational epigenetics. Epigenomics. 2009;1(1):111–117.
  • Skinner MK. What is an epigenetic transgenerational phenotype? F3 or F2. Reprod Toxicol. 2008;25(1):2–6.
  • Skinner MK. Environmental epigenetic transgenerational inheritance and somatic epigenetic mitotic stability. Epigenetics. 2011;6(7):838–842.
  • Anway MD, Cupp AS, Uzumcu M, et al. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science. 2005;308(5727):1466–1469.
  • Klastrup LK, Bak ST, Nielsen AL. The influence of paternal diet on sncRNA-mediated epigenetic inheritance. Mol Genet Genomics. 2019;294(1):1–11.
  • Gapp K, Jawaid A, Sarkies P, et al. Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice. Nat Neurosci. 2014;17(5):667–669.
  • Ben Maamar M, Sadler-Riggleman I, Beck D, et al. Epigenetic transgenerational inheritance of altered sperm histone retention sites. Sci Rep. 2018;8(1):1–10.
  • Ben Maamar M, Sadler-Riggleman I, Beck D, et al. Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of disease. Environ Epigenet. 2018;4(2):dvy010.
  • Skinner MK, Ben Maamar M, Sadler-Riggleman I, et al. Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease. Epigenetics Chromatin. 2018;11(1):1–24. .
  • McBirney M, King SE, Pappalardo M, et al. Atrazine induced epigenetic transgenerational inheritance of disease, lean phenotype and sperm epimutation pathology biomarkers. PloS One. 2017;12(9):e0184306. .
  • King SE, McBirney M, Beck D, et al. Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease. Environ Epigenet. 2019;5(2):dvz008.
  • Nilsson E, King SE, McBirney M, et al. Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases. PloS One. 2018;13(8):e0202662. .
  • Benbrook CM. Trends in glyphosate herbicide use in the United States and globally. Environ Sci Eur. 2016;28(1):3.
  • Myers JP, Antoniou MN, Blumberg B, et al. Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environ Health. 2016;15:19.
  • Davoren MJ, Schiestl RH. Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research. Carcinogenesis. 2018;39(10):1207–1215.
  • ATSDR. Toxicological profile for glyphosate. U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry. ATSDR.; 2019.
  • Mesnage R, Defarge N, Spiroux de Vendomois J, et al. Potential toxic effects of glyphosate and its commercial formulations below regulatory limits. Food Chem Toxicol. 2015;84:133–153.
  • Kubsad D, Nilsson EE, King SE, et al. Assessment of glyphosate induced epigenetic transgenerational inheritance of pathologies and sperm epimutations: generational toxicology. Sci Rep. 2019;9(1):6372.
  • Mertens M, Hoss S, Neumann G, et al. Glyphosate, a chelating agent-relevant for ecological risk assessment? Environ Sci Pollut Res Int. 2018;25(6):5298–5317.
  • Van Bruggen AHC, He MM, Shin K, et al. Environmental and health effects of the herbicide glyphosate. Sci Total Environ. 2018;616–617:255–268.
  • Stouder C, Paoloni-Giacobino A. Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm. Reproduction. 2010;139(2):373–379.
  • Guerrero-Bosagna C, Covert T, Haque MM, et al. Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers. Reprod Toxicol. 2012;34(4):694–707. .
  • Euorpean Food Safety Authority E. Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate. Efsa J. 2015;13(11):4302.
  • Guerrero-Bosagna C, Settles M, Lucker B, et al. Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome. PloS One. 2010;5(9):e13100.
  • Skinner MK, Guerrero-Bosagna C. Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions. BMC Genomics. 2014;15(1):692.
  • Minneci F, Piovesan D, Cozzetto D, et al. FFPred 2.0: improved homology-independent prediction of gene ontology terms for eukaryotic protein sequences. PloS One. 2013;8(5):e63754.
  • Ben Maamar M, King SE, Nilsson E, et al. Epigenetic transgenerational inheritance of parent-of-origin allelic transmission of outcross pathology and sperm epimutations. Dev Biol. 2020;458(1):106–119.
  • Rawla P. Epidemiology of prostate cancer. World J Oncol. 2019;10(2):63–89.
  • Hales CM, Carroll MD, Fryar CD, et al. Prevalence of obesity among adults and youth: United States, 2015–2016. Hyattsville, MD: National Center for Health Statistics; 2017.
  • Rathke C, Baarends WM, Awe S, et al. Chromatin dynamics during spermiogenesis. Biochim Biophys Acta. 2014;1839(3):155–168.
  • Devlin B, Roeder K, Wasserman L. Analysis of multilocus models of association. Genet Epidemiol. 2003;25(1):36–47.
  • Higdon R, van Belle G, Kolker E. A note on the false discovery rate and inconsistent comparisons between experiments. Bioinformatics. 2008;24(10):1225–1228.
  • Yang H, Churchill G. Estimating p-values in small microarray experiments. Bioinformatics. 2007;23(1):38–43.
  • Bretz F, Landgrebe J, Brunner E. Multiplicity issues in microarray experiments. Methods Inf Med. 2005;44(3):431–437.
  • Jung SH. Sample size and power calculation for molecular biology studies. Methods Mol Biol. 2010;620:203–218.
  • Nilsson R, Bjorkegren J, Tegner J. On reliable discovery of molecular signatures. BMC Bioinformatics. 2009;10:38.