Advanced search
Publication Cover
Epigenetics Volume 17, 2022 - Issue 11
Submit an article Journal homepage
801
Views
0
CrossRef citations to date
0
Altmetric
Research Paper

Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines

Christopher W. Kuzawaa Department of Anthropology, Northwestern University, Evanston, USA;b Institute for Policy Research, Northwestern University, Evanston, USACorrespondence[email protected]
View further author information
,
Calen P. Ryanc Butler Columbia Aging Center, Department of Epidemiology, Columbia University Mailman School of Public HealthView further author information
,
Linda S. Adaird Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel HillView further author information
,
Nanette R. Leee USC-Office of Population Studies Foundation, University of San Carlos, Talamban, Cebu CityView further author information
,
Delia B. Carbae USC-Office of Population Studies Foundation, University of San Carlos, Talamban, Cebu CityView further author information
,
Julia L. MacIsaacf Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;g BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada;h Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, CanadaView further author information
,
Kristy Deverf Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;g BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada;h Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, CanadaView further author information
,
Parmida Atashzayf Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;g BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada;h Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, CanadaView further author information
,
Michael S. Koborf Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;g BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada;h Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, CanadaView further author information
&
Thomas W. McDadea Department of Anthropology, Northwestern University, Evanston, USA;b Institute for Policy Research, Northwestern University, Evanston, USAView further author information
 show all
Pages 1535-1545 | Received 10 Feb 2022, Accepted 18 Apr 2022, Published online: 14 May 2022

References

  • Barker D. Mothers, Babies, and Disease in Later Life. London: BMJ Publishing; 1994.
  • Gluckman PD, Hanson MA. Developmental Origins of Health and Disease. Cambridge: Cambridge University Press; 2006.
  • Hoffman DJ, Powell TL, Barrett ES, et al. Developmental origins of metabolic diseases. Physiol Rev. 2021;101(3):739–795.
  • Jylhava J, Pedersen NL, Hagg S. Biological Age Predictors. EBioMedicine. 2017;21:29–36.
  • Langley-Evans SC, Langley-Evans AJ, Marchand MC. Nutritional programming of blood pressure and renal morphology. Arch Physiol Biochem. 2003;111:8–16.
  • Reynolds CM, Vickers MH. Utility of Small Animal Models of Developmental Programming. Methods Mol Biol. 2018;1735:145–163.
  • Horvath S, Raj K. DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev. 2018;19(6):371–384.
  • Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14(10):R115.
  • Hannum G, Guinney J, Zhao L, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2013;49(2):359–367.
  • Levine ME, Lu AT, Quach A, et al. An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY). 2018;10(4):573–591.
  • Lu AT, Quach A, Wilson JG, et al. DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging (Albany NY). 2019;11(2):303–327.
  • Lu AT, Seeboth A, Tsai PC, et al. DNA methylation-based estimator of telomere length. Aging (Albany NY). 2019;11(16):5895–5923.
  • Belsky DW, Caspi A, Corcoran DL, et al. DunedinPACE, a DNA methylation biomarker of the pace of aging. Elife. 2022;11: e73420.
  • Binder AM, Corvalan C, Mericq V, et al. Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls. Epigenetics. 2018;13(1):85–94.
  • Simpkin AJ, Howe LD, Tilling K, et al. The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort. Int J Epidemiol. 2017;46(2):549–558.
  • Simpkin AJ, Hemani G, Suderman M, et al. Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies. Hum Mol Genet. 2016;25(1):191–201.
  • Madden RA, McCartney DL, Walker RM, et al. Birth weight associations with DNA methylation differences in an adult population. Epigenetics. 2021;16(7):783–796.
  • Kuzawa CW, Adair L, Bechayda SA, et al. Evolutionary life history theory as an organising framework for cohort studies: insights from the Cebu Longitudinal Health and Nutrition Survey. Ann Hum Biol. 2020;47(2):94–105.
  • Adair LS, Kuzawa CW, Borja J. Maternal energy stores and diet composition during pregnancy program adolescent blood pressure. Circulation. 2001;104(9):1034–1039.
  • Kuzawa CW, Adair LS. Lipid profiles in adolescent Filipinos: relation to birth weight and maternal energy status during pregnancy. Am J Clin Nutr. 2003;77(4):960–966.
  • Adair LS, Popkin BM, Akin JS, et al. Cohort profile: the Cebu longitudinal health and nutrition survey. Int J Epidemiol. 2011;40(3):619–625.
  • Ryan CP, Hayes MG, Lee NR, et al. Reproduction predicts shorter telomeres and epigenetic age acceleration among young adult women. Sci Rep. 2018;8(1):11100.
  • Kuzawa CW, Fried RL, Borja JB, et al. Maternal pregnancy C-reactive protein predicts offspring birth size and body composition in metropolitan Cebu, Philippines. J Dev Orig Health Dis. 2017;8(6):674–681.
  • Du P, Kibbe WA, Lin SM. lumi: a pipeline for processing Illumina microarray. Bioinformatics. 2008;24:1547–1548.
  • Houseman EA, Accomando WP, Koestler DC, et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics. 2012;13(1):86.
  • Aryee MJ, Jaffe AE, Corrada-Bravo H, et al. Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays. Bioinformatics. 2014;30(10):1363–1369.
  • Horvath S, Levine AJ. HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015;212(10):1563–1573.
  • Thayer ZM, Feranil AB, Kuzawa CW. Maternal cortisol disproportionately impacts fetal growth in male offspring: evidence from the Philippines. Am J Hum Biol. 2012;24(1):1–4.
  • Fried RL, Mayol NL, McDade TW, et al. Maternal metabolic adaptations to pregnancy among young women in Cebu, Philippines. Am J Hum Biol. 2017;29(5). DOI:10.1002/ajhb.23011
  • Lee J, Fried R, Thayer Z, et al. Preterm delivery as a predictor of diurnal cortisol profiles in adulthood: evidence from Cebu, Philippines. Am J Hum Biol. 2014;26(5):598–602.
  • McDade TW, Jones MJ, Miller G, et al. Birth weight and postnatal microbial exposures predict the distribution of peripheral blood leukocyte subsets in young adults in the Philippines. J Dev Orig Health Dis. 2018;9(2):198–207.
  • McDade TW, Georgiev AV, Kuzawa CW. Trade-offs between acquired and innate immune defenses in humans. Evol Med Public Health. 2016;2016(1):1–16.
  • Masterson EE, Hayes MG, Kuzawa CW, et al. Early life growth and adult telomere length in a Filipino cohort study. Am J Hum Biol. 2019;31(6):e23299.
  • Van Lieshout RJ, McGowan PO, de Vega WC, et al. Extremely Low Birth Weight and Accelerated Biological Aging. Pediatrics. 2021;147.
  • Ibanez L, Ferrer A, Marcos MV, et al. Early puberty: rapid progression and reduced final height in girls with low birth weight. Pediatrics. 2000;106(5):E72.
  • Adair LS. Size at birth predicts age at menarche. Pediatrics. 2001;107(4):E59.
  • Kuzawa CW, McDade TW, Adair LS, et al. Rapid weight gain after birth predicts life history and reproductive strategy in Filipino males. Proceedings of the National Academy of Sciences of the United States of America 2010; 107:16800–16805.
  • Stinson S. Sex differences in environmental sensitivity during growth and development. American Journal of Physical Anthropology. 1985;28(S6):123–147.
  • Clutton-Brock TH, Guinness FE, Albon SD. Red deer: behavior and ecology of two sexes. Chicago: University of Chicago Press; 1982.
  • Adair LS, Pollitt E. Outcome of maternal nutritional supplementation: a comprehensive review of the Bacon Chow study. Am J Clin Nutr. 1985;41(5):948–978.
  • Kuzawa CW. Developmental origins of life history: growth, productivity, and reproduction. Am J Hum Biol. 2007;19(5):654–661.
  • Kuzawa CW. Fetal origins of developmental plasticity: are fetal cues reliable predictors of future nutritional environments? Am J Hum Biol. 2005;17(1):5–21.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.