Drug Value of Drynariae Rhizoma Root-Derived Extracellular Vesicles for Neurodegenerative Diseases Based on Proteomics and Bioinformatics

References

• Colombo M, Raposo G, Thery C. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol. 2014;30:255–8. doi:10.1146/annurev-cellbio-101512-122326
   PubMed Web of Science ®Google Scholar
• Tkach M, Thery C. Communication by Extracellular Vesicles: where We Are and Where We Need to Go. Cell. 2016;164(6):1226–1232. doi:10.1016/j.cell.2016.01.043
   PubMed Web of Science ®Google Scholar
• Maas SLN, Breakefield XO, Weaver AM. Extracellular Vesicles: unique Intercellular Delivery Vehicles. Trends Cell Biol. 2017;27(3):172–188. doi:10.1016/j.tcb.2016.11.003
   PubMed Web of Science ®Google Scholar
• Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200(4):373–383. doi:10.1083/jcb.201211138
   PubMed Web of Science ®Google Scholar
• Li P, Kaslan M, Lee SH, Yao J, Gao Z. Progress in Exosome Isolation Techniques. Theranostics. 2017;7(3):789–804. doi:10.7150/thno.18133
   PubMed Web of Science ®Google Scholar
• Halperin W, Jensen WA. Ultrastructural changes during growth and embryogenesis in carrot cell cultures. J Ultrastruct Res. 1967;18(3):428–443. doi:10.1016/S0022-5320(67)80128-X
   PubMedGoogle Scholar
• Regente M, Corti-Monzon G, Maldonado AM, Pinedo M, Jorrin J. de la Canal L. Vesicular fractions of sunflower apoplastic fluids are associated with potential exosome marker proteins. FEBS Lett. 2009;583(20):3363–3366. doi:10.1016/j.febslet.2009.09.041
   PubMed Web of Science ®Google Scholar
• Raimondo S, Naselli F, Fontana S, Monteleone F, Lo Dico A, Saieva L, Zito G, Flugy A, Manno M, Di Bella MA, et al. Citrus limon -derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death. Oncotarget. 2015;6(23):19514–19527. doi:10.18632/oncotarget.4004
   PubMedGoogle Scholar
• Stanly C, Alfieri M, Ambrosone A, Leone A, Fiume I, Grapefruit-Derived Micro PG. Nanovesicles Show Distinct Metabolome Profiles and Anticancer Activities in the A375 Human Melanoma Cell Line. Cells. 2020;9:12
   Web of Science ®Google Scholar
• Shao H, Im H, Castro CM, Breakefield X, Weissleder R, Lee H. New Technologies for Analysis of Extracellular Vesicles. Chem Rev. 2018;118(4):1917–1950. doi:10.1021/acs.chemrev.7b00534
   PubMed Web of Science ®Google Scholar
• Rutter BD, Innes RW. Extracellular Vesicles Isolated from the Leaf Apoplast Carry Stress-Response Proteins. Plant Physiol. 2017;173(1):728–741. doi:10.1104/pp.16.01253
   PubMed Web of Science ®Google Scholar
• Regente M, Pinedo M, San Clemente H, Balliau T, Jamet E, de la Canal L. de la Canal L. Plant extracellular vesicles are incorporated by a fungal pathogen and inhibit its growth. J Exp Bot. 2017;68(20):5485–5495. doi:10.1093/jxb/erx355
   PubMed Web of Science ®Google Scholar
• De Palma M, Ambrosone A, Leone A, Del Gaudio P, Ruocco M, Turiak L, Bokka, R, Fiume, I, Tucci, M, Pocsfalvi, G, et al. Plant Roots Release Small Extracellular Vesicles with Antifungal Activity. Plants. 2020;9:12.
   Google Scholar
• Tomoharu K, Chihiro T, Chen Z, Zhang Y. A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer’s Disease and Its Target Molecule. Front Pharmacol. 2017;8:1–13. doi:10.3389/fphar.2017.00001
   PubMed Web of Science ®Google Scholar
• Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13(11):2498–2504. doi:10.1101/gr.1239303
   PubMed Web of Science ®Google Scholar
• Chin CH, Chen SH, Wu HH, Ho CW, Ko MT, Lin CY. cytoHubba: identifying hub objects and sub-networks from complex interactome. BMC Syst Biol. 2014;8(Suppl 4):S11. doi:10.1186/1752-0509-8-S4-S11
   PubMed Web of Science ®Google Scholar
• Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ; Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, et al. Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods. 2012;56(2):293–304. doi:10.1016/j.ymeth.2012.01.002
   PubMed Web of Science ®Google Scholar
• Corrado C, Raimondo S, Chiesi A, Ciccia F, De Leo G, Alessandro R. Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications. Int J Mol Sci. 2013;14(3):5338–5366. doi:10.3390/ijms14035338
   PubMed Web of Science ®Google Scholar
• Movahed N, Cabanillas DG, Wan J, Vali H, Laliberte JF, Zheng H. Turnip Mosaic Virus Components Are Released into the Extracellular Space by Vesicles in Infected Leaves. Plant Physiol. 2019;180(3):1375–1388. doi:10.1104/pp.19.00381
   PubMed Web of Science ®Google Scholar
• Patrick BA, Das A, Jaiswal AK. NAD(P)H:quinone oxidoreductase 1 protects bladder epithelium against painful bladder syndrome in mice. Free Radic Biol Med. 2012;53(10):1886–1893. doi:10.1016/j.freeradbiomed.2012.08.584
   PubMed Web of Science ®Google Scholar
• Gao F, Wu X, Mao X, Niu F, Zhang B, Dong J, Liu, B, et al. Astaxanthin provides neuroprotection in an experimental model of traumatic brain injury via the Nrf2/HO-1 pathway. Am J Transl Res. 2021;13(3):1483–1493.
   PubMed Web of Science ®Google Scholar
• Zhu M, Liu H, Sun K, Liu J, Mou Y, Qi D, Zhou C, Abudunaibi M, Tasiken B, Li J, et al. Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss. Biomed Pharmacother. 2020;123:109769. doi:10.1016/j.biopha.2019.109769
   PubMed Web of Science ®Google Scholar
• Margolis L, Sadovsky Y. The biology of extracellular vesicles: the known unknowns. PLoS Biol. 2019;17(7):e3000363. doi:10.1371/journal.pbio.3000363
   PubMed Web of Science ®Google Scholar
• Willms E, Johansson HJ, Mager I, Lee Y, Blomberg KE, Sadik M, et al. Cells release subpopulations of exosomes with distinct molecular and biological properties. Sci Rep. 2016;6:22519. doi:10.1038/srep22519
   PubMed Web of Science ®Google Scholar
• Andras IE, Toborek M. Extracellular vesicles of the blood-brain barrier. Tissue Barriers. 2016;4(1):e1131804. doi:10.1080/21688370.2015.1131804
   PubMedGoogle Scholar
• Kramer-Albers EM, Hill AF. Extracellular vesicles: interneural shuttles of complex messages. Curr Opin Neurobiol. 2016;39:101–107. doi:10.1016/j.conb.2016.04.016
   PubMed Web of Science ®Google Scholar
• Ibrahim A, Marban E. Exosomes: fundamental Biology and Roles in Cardiovascular Physiology. Annu Rev Physiol. 2016;78:67–83. doi:10.1146/annurev-physiol-021115-104929
   PubMed Web of Science ®Google Scholar
• Choy C, Jandial R. Breast Cancer Exosomes Breach the Blood-Brain Barrier. Neurosurgery. 2016;78(6):N10–1. doi:10.1227/NEU.0000000000001242
   PubMed Web of Science ®Google Scholar
• Zhang M, Viennois E, Prasad M, Zhang Y, Wang L, Zhang Z, Han MK, Xiao B, Xu C, Srinivasan S, et al. Edible ginger-derived nanoparticles: a novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer. Biomaterials. 2016;101:321–340. doi:10.1016/j.biomaterials.2016.06.018
   PubMed Web of Science ®Google Scholar
• Mu J, Zhuang X, Wang Q, Jiang H, Deng ZB, Wang B, Zhuang X, Wang Q, et al. Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles. Mol Nutr Food Res. 2014;58(7):1561–1573. doi:10.1002/mnfr.201300729
   PubMed Web of Science ®Google Scholar
• Wang B, Zhuang X, Deng ZB, Jiang H, Mu J, Wang Q, Xiang X, Guo H, Zhang L, Dryden G, et al. Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit. Mol Ther. 2014;22(3):522–534. doi:10.1038/mt.2013.190
   PubMed Web of Science ®Google Scholar
• Ju S, Mu J, Dokland T, Zhuang X, Wang Q, Jiang H, Xiang X, Deng Z-B, Wang B, Zhang L, et al. Grape exosome-like nanoparticles induce intestinal stem cells and protect mice from DSS-induced colitis. Mol Ther. 2013;21(7):1345–1357. doi:10.1038/mt.2013.64
   PubMed Web of Science ®Google Scholar
• Jung KA, Kwak MK. The Nrf2 system as a potential target for the development of indirect antioxidants. Molecules. 2010;15(10):7266–7291. doi:10.3390/molecules15107266
   PubMed Web of Science ®Google Scholar
• Johnson J, Maher P, Hanneken A. The flavonoid, eriodictyol, induces long-term protection in ARPE-19 cells through its effects on Nrf2 activation and phase 2 gene expression. Invest Ophthalmol Vis Sci. 2009;50(5):2398–2406. doi:10.1167/iovs.08-2088
   PubMed Web of Science ®Google Scholar
• Osama A, Zhang J, Yao J, Yao X, Fang J. Nrf2: a dark horse in Alzheimer’s disease treatment. Ageing Res Rev. 2020;64:101206. doi:10.1016/j.arr.2020.101206
   PubMed Web of Science ®Google Scholar
• Wang W, Li H, Yu J, Hong M, Zhou J, Zhu L, Wang Y, Luo M, Xia Z, Yang Z-J, et al. Protective Effects of Chinese Herbal Medicine Rhizoma drynariae in Rats After Traumatic Brain Injury and Identification of Active Compound. Mol Neurobiol. 2016;53(7):4809–4820. doi:10.1007/s12035-015-9385-x
   PubMed Web of Science ®Google Scholar
• Li H, Huang C, Zhu J, Gao K, Fang J, Li H. Lutein Suppresses Oxidative Stress and Inflammation by Nrf2 Activation in an Osteoporosis Rat Model. Med Sci Monit. 2018;24:5071–5075. doi:10.12659/MSM.908699
   PubMed Web of Science ®Google Scholar
• Zhang S, Li D, Yang JY, Yan TB. Plumbagin protects against glucocorticoid-induced osteoporosis through Nrf-2 pathway. Cell Stress Chaperones. 2015;20(4):621–629. doi:10.1007/s12192-015-0585-0
   PubMed Web of Science ®Google Scholar
• Qu L, Ji L, Wang C, Luo H, Li S, Peng W, Yin F, Lu D, Liu X, Kong L, et al. Synthesis and evaluation of multi-target-directed ligands with BACE-1 inhibitory and Nrf2 agonist activities as potential agents against Alzheimer’s disease. Eur J Med Chem. 2021;219:113441. doi:10.1016/j.ejmech.2021.113441
   PubMed Web of Science ®Google Scholar