242
Views
13
CrossRef citations to date
0
Altmetric
Original Investigation

Reduced serum VGF levels were reversed by antidepressant treatment in depressed patients

, , , , , , , & show all
Pages 586-591 | Received 18 Jan 2016, Accepted 08 Aug 2016, Published online: 22 Sep 2016

References

  • Alder J, Thakker-Varia S, Bangasser DA, Kuroiwa M, Plummer MR, Shors TJ, Black IB. 2003. Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J Neurosci. 23:10800–10808.
  • Allaman I, Fiumelli H, Magistretti PJ, Martin JL. 2011. Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes. Psychopharmacology (Berl). 216:75–84.
  • Altar CA, Laeng P, Jurata LW, Brockman JA, Lemire A, Bullard J, Bukhman Y, Young TA, Charles V, Palfreyman MG. 2004. Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways. J Neurosci. 24:2667–2677.
  • Ballas C, Staab JP, Evans DL. 2002. Strategies for treatment-resistant depression. Psychopharmacol Bull. 36:39–62.
  • Bonni A, Ginty DD, Dudek H, Greenberg ME. 1995. Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Mol Cell Neurosci. 6:168–183.
  • Bozdagi O, Rich E, Tronel S, Sadahiro M, Patterson K, Shapiro ML, Alberini CM, Huntley GW, Salton SR. 2008. The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism. J Neurosci. 28:9857–9869.
  • Busse S, Bernstein HG, Busse M, Bielau H, Brisch R, Mawrin C, Müller S, Sarnyai Z, Gos T, Bogerts B, Steiner J. 2012. Reduced density of hypothalamic VGF-immunoreactive neurons in schizophrenia: a potential link to impaired growth factor signaling and energy homeostasis. Eur Arch Psychiatry Clin Neurosci. 262:365–374.
  • Cattaneo A, Bocchio-Chiavetto L, Zanardini R, Milanesi E, Placentino A, Gennarelli M. 2010a. Reduced peripheral brain-derived neurotrophic factor mRNA levels are normalised by antidepressant treatment. Int J Neuropsychopharmacol. 13:103–108.
  • Cattaneo A, Gennarelli M, Uher R, Breen G, Farmer A, Aitchison KJ, Craig IW, Anacker C, Zunsztain PA, McGuffin P, Pariante CM. 2013. Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal 'targets'. Neuropsychopharmacology. 38:377–385.
  • Cattaneo A, Sesta A, Calabrese F, Nielsen G, Riva MA, Gennarelli M. 2010b. The expression of VGF is reduced in leukocytes of depressed patients and it is restored by effective antidepressant treatment. Neuropsychopharmacology. 35:1423–1428.
  • Conti B, Maier R, Barr AM, Morale MC, Lu X, Sanna PP, Bilbe G, Hoyer D, Bartfai T. 2007. Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine. Mol Psychiatry. 12:167–189.
  • de Kloet ER, Molendijk ML. 2016. Coping with the forced swim stressor: towards understanding an adaptive mechanism. Neural Plast. 2016:6503162.
  • Duric V, Duman RS. 2013. Depression and treatment response: dynamic interplay of signaling pathways and altered neural processes. Cell Mol Life Sci. 70:39–53.
  • Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry. 23:56–62.
  • Hunsberger JG, Newton SS, Bennett AH, Duman CH, Russell DS, Salton SR, Duman RS. 2007. Antidepressant actions of the exercise-regulated gene VGF. Nat Med. 13:1476–1482.
  • Lecube A, Poca MA, Colome N, Bech-Serra JJ, Hernandez C, Garcia-Ramirez M, Gándara D, Canals F, Simó R. 2012. Proteomic analysis of cerebrospinal fluid from obese women with idiopathic intracranial hypertension: a new approach for identifying new candidates in the pathogenesis of obesity. J Neuroendocrinol. 24:944–952.
  • Levi A, Eldridge JD, Paterson BM. 1985. Molecular cloning of a gene sequence regulated by nerve growth factor. Science. 229:393–395.
  • Lewis JE, Brameld JM, Jethwa PH. 2015. Neuroendocrine Role for VGF. Front Endocrinol (Lausanne). 6:3.
  • Lin P, Wang C, Xu B, Gao S, Guo J, Zhao X, Huang H, Zhang J, Chen X, Wang Q, Zhou W. 2014. The VGF-derived peptide TLQP62 produces antidepressant-like effects in mice via the BDNF/TrkB/CREB signaling pathway. Pharmacol Biochem Behav. 120:140–148.
  • Malberg JE, Monteggia LM. 2008. VGF, a new player in antidepressant action? Sci Signal. 1:pe19.
  • Molendijk ML, de Kloet ER. 2015. Immobility in the forced swim test is adaptive and does not reflect depression. Psychoneuroendocrinology. 62:389–391.
  • Newton SS, Collier EF, Hunsberger J, Adams D, Terwilliger R, Selvanayagam E, Duman RS. 2003. Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors. J Neurosci. 23:10841–10851.
  • Rasmusson AM, Shi L, Duman R. 2002. Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock. Neuropsychopharmacology. 27:133–142.
  • Salton SR, Fischberg DJ, Dong KW. 1991. Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells. Mol Cell Biol. 11:2335–2349.
  • Stein S, Winnik S, Matter CM. 2015. Brain-derived neurotrophic factor Val66Met polymorphism in depression and thrombosis: SIRT1 as a possible mediator. Eur Heart J. pii:ehv692.
  • Tanis KQ, Newton SS, Duman RS. 2007. Targeting neurotrophic/growth factor expression and signaling for antidepressant drug development. CNS Neurol Disord Drug Targets. 6:151–160.
  • Thakker-Varia S, Alder J. 2009. Neuropeptides in depression: role of VGF. Behav Brain Res. 197:262–278.
  • Thakker-Varia S, Jean YY, Parikh P, Sizer CF, Jernstedt Ayer J, Parikh A, Hyde TM, Buyske S, Alder J. 2010. The neuropeptide VGF is reduced in human bipolar postmortem brain and contributes to some of the behavioral and molecular effects of lithiummortem. J Neurosci. 30:9368–9380.
  • Thakker-Varia S, Krol JJ, Nettleton J, Bilimoria PM, Bangasser DA, Shors TJ, Black IB, Alder J. 2007. The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus. J Neurosci. 27:12156–12167.
  • Willner P, Scheel-Kruger J, Belzung C. 2013. The neurobiology of depression and antidepressant action. Neurosci Biobehav Rev. 37:2331–2371.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.