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Original Investigations

Plasma brain-derived neurotrophic factor (pBDNF) and executive dysfunctions in patients with major depressive disorder

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Pages 519-530 | Received 06 Jul 2017, Accepted 19 Dec 2017, Published online: 02 Feb 2018

References

  • Ackenheil M, Stotz G, Dietz-Bauer R, Vossen A. 1998. M.I.N.I: International Neuropsychiatric Interview – German Version 5.0.0. Deutschland: München.
  • Archer T, Josefsson T, Lindwall M. 2014. Effects of physical exercise on depressive symptoms and biomarkers in depression. CNS Neurol Disord Drug Targets. 13:1640–1653.
  • Aschenbrenner A, Tucha O, Lange K, editors. 2000. RWT Regensburger Wortflüssigkeits-Test. Handanweisung. Göttingen: Hogrefe.
  • Autry AE, Monteggia LM. 2012. Brain-derived neurotrophic factor and neuropsychiatric disorders. Pharmacol Rev. 64:238–258.
  • Beblo T, Sinnamon G, Baune BT. 2011. Specifying the neuropsychology of affective disorders: clinical, demographic and neurobiological factors. Neuropsychol Rev. 21:337–359.
  • Becker S, Macqueen G, Wojtowicz JM. 2009. Computational modeling and empirical studies of hippocampal neurogenesis-dependent memory: Effects of interference, stress and depression. Brain Res. 1299:45–54.
  • Becker S, Wojtowicz JM. 2007. A model of hippocampal neurogenesis in memory and mood disorders. Trends Cogn Sci (Regul Ed.). 11:70–76.
  • Begliuomini S, Lenzi E, Ninni F, Casarosa E, Merlini S, Pluchino N, Valentino V, Luisi S, Luisi M, Genazzani AR, et al. 2008. Plasma brain-derived neurotrophic factor daily variations in men: correlation with cortisol circadian rhythm. J Endocrinol. 197:429–435.
  • Bjorkholm C, Monteggia LM. 2016. BDNF - a key transducer of antidepressant effects. Neuropharmacology. 102:72–79.
  • Bocchio-Chiavetto L, Bagnardi V, Zanardini R, Molteni R, Nielsen MG, Placentino A, Giovannini C, Rillosi L, Ventriglia M, Riva MA, et al. 2010. Serum and plasma BDNF levels in major depression: a replication study and meta-analyses. World J Biol Psychiatry. 11:763–773.
  • Borenstein M, Hedges LV, Higgins JP, Rothstein HR. 2010. A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Synth Methods. 1:97–111.
  • Bortolato B, Carvalho AF, McIntyre RS. 2014. Cognitive dysfunction in major depressive disorder: a state-of-the-art clinical review. CNS Neurol Disord Drug Targets. 13:1804–1818.
  • Buttenschøn HN, Demontis D, Kaas M, Elfving B, Mølgaard S, Gustafsen C, Kaerlev L, Petersen CM, Børglum AD, Mors O, et al. 2015. Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF. Transl Psychiatry. 5:e677.
  • Cain SW, Chang A-M, Vlasac I, Tare A, Anderson C, Czeisler CA, Saxena R. 2017. Circadian rhythms in plasma brain-derived neuritrophic factor differ in men and women. J Biol Rhythms. 32:75–82.
  • Carvalho AF, Köhler CA, McIntyre RS, Knöchel C, Brunoni AR, Thase ME, Quevedo J, Fernandes BS, Berk M. 2015. Peripheral vascular endothelial growth factor as a novel depression biomarker: a meta-analysis. Psychoneuroendo-crinology. 62:18–26.
  • Chiou YJ, Huang TL. 2017. Serum brain-derived neurotrophic factors in Taiwanese patients with drug-naïve first-episode schizophrenia: effects of antipsychotics. World J Biol Psychiatry. 18:382–391.
  • Choi S-W, Bhang S, Ahn J-H. 2011. Diurnal variation and gender differences of plasma brain-derived neurotrophic factor in healthy human subjects. Psychiatry Res. 186:427–430.
  • Day JJ, Sweatt JD. 2011. Epigenetic mechanisms in cognition. Neuron. 70:813–829.
  • Day JJ, Sweatt JD. 2012. Epigenetic treatments for cognitive impairments. Neuropsychopharmacology. 37:247–260.
  • Dias VV, Brissos S, Frey BN, Andreazza AC, Cardoso C, Kapczinski F. 2009. Cognitive function and serum levels of brain-derived neurotrophic factor in patients with bipolar disorder. Bipolar Disord. 11:663–671.
  • Dishman RK, Berthoud H-R, Booth FW, Cotman CW, Edgerton VR, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, et al. 2006. Neurobiology of exercise. Obesity (Silver Spring). 14:345–356.
  • Elzinga BM, Molendijk ML, Oude Voshaar RC, Bus BAA, Prickaerts J, Spinhoven P, Penninx BJWH. 2011. The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met. Psychopharmacology (Berl). 214:319–328.
  • Fernandes BS, Molendijk ML, Köhler CA, Soares JC, Leite CMGS, Machado-Vieira R, Ribeiro TL, Silva JC, Sales PMG, Quevedo J, et al. 2015. Peripheral brain-derived neurotrophic factor (BDNF) as a biomarker in bipolar disorder: a meta-analysis of 52 studies. BMC Med. 13:289.
  • Gorwood P. 2008. Neurobiological mechanisms of anhedonia. Dialogues Clin Neurosci. 10:291–299.
  • Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry. 23:56–62.
  • Holm S. 1979. A simple sequentially rejective multiple test procedure. Scand. J. Stat 6:665–670.
  • Huang T, Larsen KT, Ried-Larsen M, Moller NC, ndersen LB. 2014. The effects of physical activity and exercise on brain-derived neurotrophic factor in healthy humans: a review. Scand J Med Sci Sports. 24:1–10.
  • Komulainen P, Pedersen M, Hänninen T, Bruunsgaard H, Lakka TA, Kivipelto M, Hassinen M, Rauramaa TH, Pedersen BK, Rauramaa R, et al. 2008. BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study. Neurobiol Learn Mem. 90:596–603.
  • Lamberty GJ, Putnam SH, Chatel DM, Bieliauskas LA, Adams KM. 1994. Derived trail making test indices. Neuropsychiat Neuropsychol Behav Neurol. 7:230–234.
  • Laske C, Stransky E, Leyhe T, Eschweiler GW, Wittorf A, Richartz E, Bartels M, Buchkremer G, Schott K. 2006. Stage-dependent BDNF serum concentrations in Alzheimer's disease. J Neural Transm (Vienna). 113:1217–1224.
  • Lehrl S. 1969. Mehrfachwahl-Wortschatz-Intelligenztest (MWT-B). Erlangen: Perimed Fachbuch Verlagsgesellschaft mbH.
  • Lewin J, Schmitt AO, Adorjan P, Hildmann T, Piepenbrock C. 2004. Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates. Bioinformatics. 20:3005–3012.
  • Lu Y, Christian K, Lu B. 2008. BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol Learn Mem. 89:312–323.
  • Mamounas LA, Blue ME, Siuciak JA, Altar CA. 1995. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. J Neurosci. 15:7929–7939.
  • Molendijk ML, Bus BAA, Spinhoven P, Penninx BWJH, Kenis G, Prickaerts J, Voshaar RCO, Elzinga BM. 2011. Serum levels of brain-derived neurotrophic factor in major depressive disorder: state-trait issues, clinical features and pharmacological treatment. Mol Psychiatry. 16:1088–1095.
  • Mössner R, Mikova O, Koutsilieri E, Saoud M, Ehlis A-C, Müller N, Fallgatter AJ, Riederer P. 2007. Consensus paper of the WFSBP task force on biological markers: biological markers in depression. World J Biol Psychiatry. 8:141–174.
  • Murphy M, Sarginson JE, Ryan HS, O´Hara R, Schatzberg AF, Lazzeroni LC. 2013. BDNF and CREB1 genetic variants interact to affect antidepressant treatment outcomes in geriatric depression. Pharmacogenet Genomics. 23:301–313.
  • Nakano Y, Baba H, Maeshima H, Kitajima A, Sakai Y, Baba K, Suzuki T, Mimura M, Arai H. 2008. Executive dysfunction in medicated, remitted state of major depression. J Affect Disord 111:46–51.
  • Neu P, Bajbouj M, Schilling A, Godemann F, Berman RM, Schlattmann P. 2005. Cognitive function over the treatment course of depression in middle-aged patients: correlation with brain MRI signal hyperintensities. J Psychiatr Res. 39:129–135.
  • Nicod J, Wagner S, Vonberg F, Bhomra A, Schlicht KF, Tadic A, Mott R, Lieb K, Flint J. 2016. The amount of mitochondrial DNA in blood reflects the course of a depressive episode. Biol Psychiatry. 80:e41–e42.
  • Oral E, Canpolat S, Yildirim S, Gulec M, Aliyev E, Aydin N. 2012. Cognitive functions and serum levels of brain-derived neurotrophic factor in patients with major depressive disorder. Brain Res Bull. 88:454–459.
  • Piccinni A, Marazziti D, Del Debbio A, Bianchi C, Roncaglia I, Mannari C, Origlia N, Catena Dell'Osso M, Massimetti G, Domenici L, et al. 2008. Diurnal variation of plasma brain-derived neurotrophic factor (BDNF) in humans: an analysis of sex differences. Chronobiol Int. 25:819–826.
  • Polyakova M, Stuke K, Schuemberg K, Mueller K, Schoenknecht P, Schroeter ML. 2015. BDNF as a biomarker for successful treatment of mood disorders: a systematic & quantitative meta-analysis. J Affect Disord. 174:432–440.
  • Reitan RM. 1979. Trail making test - manual for administration and scoring. Tuscon (Arizona): Reitan Neuropsychology Laboratory.
  • Reppermund S, Ising M, Lucae S, Zihl J. 2009. Cognitive impairment in unipolar depression is persistent and non-specific: further evidence for the final common pathway disorder hypothesis. Psychol Med. 39:603–614.
  • Reppermund S, Zihl J, Lucae S, Horstmann S, Kloiber S, Holsboer F, Ising M. 2007. Persistent cognitive impairment in depression: the role of psychopathology and altered hypothalamic-pituitary-adrenocortical (HPA) system regulation. Biol Psychiatry. 62:400–406.
  • Rudenko A, Tsai LH. 2014. Epigenetic modification in the nervous system nd their impact upon cognitive impairments. Neuropharmacology. 80:70–82.
  • Sen S, Duman R, Sanacora G. 2008. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry. 64:527–532.
  • Snyder HR. 2013. Major depressive disorder is associated with broad impairments on neuropsychological measures of executive function: a meta-analysis and review. Psychol Bull. 139:81–132.
  • Svenningsson P, Kim Y, Warner-Schmidt J, Oh YS, Greengard P. 2013. P11 and its role in depression and therapeutic responses to antidepressants. Nat Rev Neurosci 14:673–680.
  • Tadić A, Gorbulev S, Dahmen N, Hiemke C, Braus DF, Roschke J, van Calker D, Wachtlin D, Kronfeld K, Gorbauch T, et al. 2010. Rationale and design of the randomised clinical trial comparing early medication change (EMC) strategy with treatment as usual (TAU) in patients with major depressive disorder - the EMC trial. Trials. 11:21.
  • Tadić A, Müller-Engling L, Schlicht KF, Kotsiari A, Dreimüller N, Kleimann A, Bleich S, Lieb K, Frieling H. 2014. Methylation of the promoter of brain-derived neurotrophic factor exon IV and antidepressant response in major depression. Mol Psychiatry. 19:281–283.
  • Tadić A, Wachtlin D, Berger M, Braus DF, van Calker D, Dahmen N, Dreimüller N, Engel A, Gorbulev S, Helmreich I, et al. 2016. Randomized controlled study of early medication change for non-improvers to antidepressant therapy in major depression-The EMC trial. Eur Neuropsychophar-macol. 26:705–716.
  • Tadić A, Wagner S, Schlicht KF, Peetz D, Borysenko L, Dreimüller N, Hiemke C, Lieb K. 2011. The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: a pilot study. Prog Neuropsychopharmacol Biol Psychiatry 35:415–420.
  • Taliaz D, Loya A, Gersner R, Haramati S, Chen A, Zangen A. 2011. Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor. J Neurosci 31:4475–4483.
  • Thomas AJ, Gallagher P, Robinson LJ, Porter RJ, Young AH, Ferrier IN, O'Brien JT. 2009. A comparison of neurocognitive impairment in younger and older adults with major depression. Psychol Med 39:725–733.
  • Tombaugh TN. 2004. Trail Making Test A and B: normative data stratified by age and education. Arch Clin Neuropsychol 19:203–214.
  • Tombaugh TN, Kozak J, Rees L. 1999. Normative data stratified by age and education for two measures of verbal fluency: FAS and animal naming. Arch Clin Neuropsychol 14:167–177.
  • Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. 2006. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9:519–525.
  • Wagner S, Doering B, Helmreich I, Lieb K, Tadic A. 2012. A meta-analysis of executive dysfunctions in unipolar major depressive disorder without psychotic symptoms and their changes during antidepressant treatment. Acta Psychiatr Scand 125:281–292.
  • Wagner S, Helmreich I, Lieb K, Tadic A. 2011a. Standardized rater training for the Hamilton Depression Rating Scale (HAMD-17) and the Inventory of Depressive Symptoms (IDS-C30). Psychopathology 44:68–70.
  • Wagner S, Helmreich I, Dahmen N, Lieb K, Tadic A. 2011. Reliability of three alternate forms of the trail making tests a and B. Arch Clin Neuropsychol 26:314–321.
  • Wagner S, Helmreich I, Wollschläger D, Meyer K, Kaaden S, Reiff J, et al. 2018. Early improvement of executive test performance during antidepressant treatment predicts treatment outcome in patients with major depressive disorder. PLoS One. Under revision.
  • Wang L, Ashley-Koch A, Steffens DC, Krishnan KRR, Taylor WD. 2012. Impact of BDNF Val66Met and 5-HTTLPR polymorphism variants on neural substrates related to sadness and executive function. Genes Brain Behav. 11:352–359.
  • Warner-Schmidt JL, Chen EY, Zhang X, Marshall JJ, Morozov A, Svenningsson P, Greengard P. 2010. A role for p11 in the antidepressant action of brain-derived neurotrophic factor. Biol Psychiatry. 68:528–535.
  • Wittchen HU, Zaudig M, Fydrich T. 1996. SKID-I/-II: Strukturiertes klinisches Interview für DSM-IV. Göttingen: Hogrefe.
  • Zheleznyakova GY, Cao H, Schioth HB. 2016. BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis. Behav Brain Funct. 12:17.

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