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Brief Reports

DNA methylation in people with anorexia nervosa: Epigenome-wide patterns in actively ill, long-term remitted, and healthy-eater women

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Pages 254-259 | Received 20 Feb 2022, Accepted 10 Jun 2022, Published online: 27 Jun 2022

References

  • Baeza-Velasco C, Lorente S, Tasa-Vinyals E, Guillaume S, Mora MS, Espinoza P. 2021. Gastrointestinal and eating problems in women with Ehlers–Danlos syndromes. Eat Weight Disord. 26(8):2645–2656.
  • Booij L, Casey KF, Antunes JM, Szyf M, Joober R, Israël M, Steiger H. 2015. DNA methylation in individuals with anorexia nervosa and in matched normal-eater controls: a genome-wide study. Int J Eat Disord. 48(7):874–882.
  • Booij L, Steiger H. 2020. Applying epigenetic science to the understanding of eating disorders: a promising paradigm for research and practice. Curr Opin Psychiatry. 33(6):515–520.
  • Breton E, Gagné-Ouellet V, Thibeault K, Guérin R, Van Lieshout R, Perron P, Hivert M, Bouchard L. 2020. Placental NEGR1 DNA methylation is associated with BMI and neurodevelopment in preschool-age children. Epigenetics. 15(3):323–335.
  • Edgar RD, Jones MJ, Meaney MJ, Turecki G, Kobor MS. 2017. BECon: a tool for interpreting DNA methylation findings from blood in the context of brain. Transl Psychiatry. 7(8):e1187–e1187.
  • Fairburn CG, Cooper Z, O’Connor M. 2008. Eating disorder examination (16.0D). In: Fairburn CG, editor. Cognitive behavior therapy and eating disorders. New York (NY): Guilford Press; p. 265–308.
  • Fairburn CG, Beglin SJ. 2008. Eating disorder examination questionnaire (EDE-Q 6.0). In: Fairburn CG, editor. Cognitive behavior therapy and eating disorders. New York (NY): Guiford Press; p. 309–313.
  • Föcking M, Sabherwal S, Cates HM, Scaife C, Dicker P, Hryniewiecka M, Wynne K, Rutten BPF, Lewis G, Cannon M, et al. 2021. Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress. Mol Psychiatry. 26(2):524–533.
  • Hebebrand J, Milos G, Wabitsch M, Teufel M, Führer D, Bühlmeier J, Libuda L, Ludwig C, Antel J. 2019. Clinical trials required to assess potential benefits and side effects of treatment of patients with anorexia nervosa with recombinant human leptin. Front Psychol. 10:769.
  • Hori K, Shimaoka K, Hoshino M. 2022. AUTS2 Gene: Keys to understanding the pathogenesis of neurodevelopmental disorders. Cells. 11(1):11.
  • Iranzo-Tatay C, Hervas-Marin D, Rojo-Bofill LM, Garcia D, Vaz-Leal FJ, Calabria I, Beato-Fernandez L, Oltra S, Sandoval J, Rojo-Moreno L. 2022. Genome-wide DNA methylation profiling in anorexia nervosa discordant identical twins. Transl Psychiatry. 12(1):15.
  • Kesselmeier M, Pütter C, Volckmar AL, Baurecht H, Grallert H, Illig T, Ismail K, Ollikainen M, Silén Y, Keski-Rahkonen A, GCAN and WTCCC3, et al. 2018. High-throughput DNA methylation analysis in anorexia nervosa confirms TNXB hypermethylation. World J Biol Psychiatry. 19(3):187–199.
  • Moran S, Arribas C, Esteller M. 2016. Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences. Epigenomics. 8(3):389–399.
  • Park C, Rosenblat JD, Brietzke E, Pan Z, Lee Y, Cao B, Zuckerman H, Kalantarova A, McIntyre RS. 2019. Stress, epigenetics and depression: a systematic review. Neurosci Biobehav Rev. 102:139–152.
  • Razin A. 1998. CpG methylation, chromatin structure and gene silencing-a three-way connection. Embo J. 17(17):4905–4908.
  • Robicsek O, Makhoul B, Klein E, Brenner B, Sarig G. 2011. Hypercoagulation in chronic post-traumatic stress disorder. Isr Med Assoc J. 13(9):548–552.
  • Rodríguez-López ML, Martínez-Magaña JJ, Ruiz-Ramos D, García AR, Gonzalez L, Tovilla-Zarate CA, Sarmiento E, Juárez-Rojop IE, Nicolini H, Gonzalez-Castro TB, et al. 2021. Individuals diagnosed with binge-eating disorder have DNA hypomethylated sites in genes of the metabolic system: a pilot study. Nutrients. 13(5):1413.
  • Sild M, Booij L. 2019. Histone deacetylase 4 (HDAC4): a new player in anorexia nervosa? Mol Psychiatry. 24(10):1425–1434.
  • Steiger H, Booij L, Kahan E, McGregor K, Thaler L, Fletcher E, Labbe A, Joober R, Israël M, Szyf M, et al. 2019. A longitudinal, epigenome-wide study of DNA methylation in anorexia nervosa: results in actively ill, partially weight-restored, long-term remitted and non-eating-disordered women. J Psychiatry Neurosci. 44(3):205–213.
  • Steiger H, Booij L. 2020. Eating disorders, heredity and environmental activation: getting epigenetic concepts into practice. J Clin Med. 9(5):1332.
  • Stevens AJ, Rucklidge JJ, Kennedy MA. 2018. Epigenetics, nutrition and mental health. Is there a relationship? Nutr Neurosci. 21(9):602–613.
  • Szyf M. 2015. Nongenetic inheritance and transgenerational epigenetics. Trends Mol Med. 21(2):134–144.
  • Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, et al. 2016. Generation of functional human serotonergic neurons from fibroblasts. Mol Psychiatry. 21(1):49–61.
  • Watanabe Y, Takeuchi K, Higa Onaga S, Sato M, Tsujita M, Abe M, Natsume R, Li M, Furuichi T, Saeki M, et al. 2010. Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. Biochem J. 432(1):47–55.
  • Zhao L, Lei W, Deng C, Wu Z, Sun M, Jin Z, Song Y, Yang Z, Jiang S, Shen M, et al. 2021. The roles of liver X receptor alpha in inflammation and inflammation-associated diseases. J Cell Physiol. 236(7):4807–4828.