Long non-coding RNAs MALAT1, MIAT and ANRIL gene expression profiles in beta-thalassemia patients: a cross-sectional analysis

References

• Thein SL. The molecular basis of β-thalassemia. Cold Spring Harb Perspect Med. 2013;3. doi:10.1101/cshperspect.a011700.
   PubMed Web of Science ®Google Scholar
• Ma J, Liu F, Du X, et al. Changes in lncRNAs and related genes in β-thalassemia minor and β-thalassemia major. Front Med. 2017;11:74–86. doi:10.1007/s11684-017-0503-1.
   PubMed Web of Science ®Google Scholar
• Cappellini MD, Cohen A, Porter J, et al. Guidelines for the Management of transfusion dependent Thalassaemia (TDT) [Internet]. 3rd ed. Nicosia Cyprus: Thalassaemia International Federation; 2014; Available from: https://www.ncbi.nlm.nih.gov/books/NBK269382/.
   Google Scholar
• Taher A, Vichinsky E, Musallam K, et al. Guidelines for the management of non transfusion dependent Thalassaemia (NTDT) [Internet]. Nicosia Cyprus: Thalassaemia International Federation; 2013; Available from: https://www.ncbi.nlm.nih.gov/books/NBK190453/.
   Google Scholar
• Kim A, Kiefer CM, Dean A. Distinctive signatures of histone methylation in transcribed coding and noncoding human β-globin sequences. Mol Cell Biol. 2007;27:1271–1279. doi:10.1128/MCB.01684-06.
   PubMed Web of Science ®Google Scholar
• Martin DI, Ward R, Suter CM. Germline epimutation: a basis for epigenetic disease in humans. Ann N Y Acad Sci. 2005; 1054:68–77. doi: 10.1196/annals.1345.009
   PubMed Web of Science ®Google Scholar
• Hanly DJ, Esteller M, Berdasco M. Interplay between long non-coding RNAs and epigenetic machinery: emerging targets in cancer? Philos Trans R Soc Lond B Biol Sci. 2018;373; doi:10.1098/rstb.2017.0074.
   PubMed Web of Science ®Google Scholar
• Engreitz JM, Ollikainen N, Guttman M. Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression. Nat Rev Mol Cell Biol. 2016;17:756–770. doi:10.1038/nrm.2016.126.
   PubMed Web of Science ®Google Scholar
• Alvarez-Dominguez JR, Hu W, Yuan B, et al. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Blood. 2014;123:570–581. doi:10.1182/blood-2013-10-530683.
   PubMed Web of Science ®Google Scholar
• Zhang X, Weissman SM, Newburger PE. Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells. RNA Biol. 2014;11:777–787. doi:10.4161/rna.28828.
   PubMed Web of Science ®Google Scholar
• Nobili L, Lionetti M, Neri A. Long non-coding RNAs in normal and malignant hematopoiesis. Oncotarget. 2016;7:50666–50681. doi:10.18632/oncotarget.9308.
   PubMed Web of Science ®Google Scholar
• Kotani, A. Guest editorial: noncoding RNA in hematopoietic system. Int J Hematol. 2014;99:529. doi: 10.1007/s12185-014-1574-2
   PubMed Web of Science ®Google Scholar
• Lai K, Jia S, Yu S, et al. Genome-wide analysis of aberrantly expressed lncRNAs and miRNAs with associated co-expression and ceRNA networks in β-thalassemia and hereditary persistence of fetal hemoglobin. Oncotarget. 2017;8:49931–49943. doi:10.18632/oncotarget.18263.
   PubMedGoogle Scholar
• Elsayh KI, Zahran AM, El-Abaseri TB, et al. Hypoxia biomarkers, oxidative stress, and circulating microparticles in pediatric patients with thalassemia in upper Egypt. Clin Appl Thromb Hemost. 2014;20:536–545. doi:10.1177/1076029612472552.
   PubMed Web of Science ®Google Scholar
• Youssry I, Soliman N, Ghamrawy M, et al. Circulating microparticles and the risk of thromboembolic events in Egyptian beta thalassemia patients. Ann Hematol. 2017;96:597–603. doi:10.1007/s00277-017-2925-x.
   PubMed Web of Science ®Google Scholar
• Zhang B, Arun G, Mao YS, et al. The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Rep. 2012;2:111–123. doi:10.1016/j.celrep.2012.06.003.
   PubMed Web of Science ®Google Scholar
• Sallé-Lefort S, Miard S, Nolin M, et al. Hypoxia upregulates Malat1 expression through a CaMKK/AMPK/HIF-1α axis. Int J Oncol. 2016;49:1731–1716. doi:10.3892/ijo.2016.3630.
   PubMed Web of Science ®Google Scholar
• Tripathi V, Ellis JD, Shen Z, et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell. 2010;39:925–938. doi:10.1016/j.molcel.2010.08.011.
   PubMed Web of Science ®Google Scholar
• Liao J, He Q, Li M, et al. LncRNA MIAT: myocardial infarction associated and more. Gene. 2016;578:158–161. doi:10.1016/j.gene.2015.12.032.
   PubMed Web of Science ®Google Scholar
• Tsuiji H, Yoshimoto R, Hasegawa Y, et al. Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1. Genes Cells. 2011;16:479–490. doi:10.1111/j.1365-2443.2011.01502.x.
   PubMed Web of Science ®Google Scholar
• Yan B, Yao J, Liu J-Y, et al. lncRNA-MIAT regulates microvascular dysfunction by functioning as a competing endogenous RNA. Circ Res. 2015;116:1143–1156. doi:10.1161/CIRCRESAHA.116.305510.
   PubMed Web of Science ®Google Scholar
• Sun C, Huang L, Li Z, et al. Long non-coding RNA MIAT in development and disease: a new player in an old game. J Biomed Sci. 2018;25:23, doi:10.1186/s12929-018-0427-3.
   PubMed Web of Science ®Google Scholar
• Wan G, Mathur R, Hu X, et al. Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway. Cell Signal. 2013;25:1086–1095. doi:10.1016/j.cellsig.2013.02.006.
   PubMed Web of Science ®Google Scholar
• Kim C, Kang D, Lee EK, et al. Long noncoding RNAs and RNA-binding proteins in oxidative stress, cellular Senescence, and Age-related diseases. Oxid Med Cell Longev. 2017. doi: 10.1155/2017/2062384
   Web of Science ®Google Scholar
• Viprakasit V, Ekwattanakit S. Clinical classification, screening and diagnosis for thalassemia. Hematol Oncol Clin North Am. 2018;32:193–211. doi:10.1016/j.hoc.2017.11.006.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Multicentre growth reference study group. WHO child growth standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. 2006:312. Available at http://www.who.int/childgrowth/standards/technical_report/en/ (last accessed 24/7/2018).
   Google Scholar
• Pitteloud N. Managing delayed or altered puberty in boys. Br Med J. 2012;345; doi:10.1136/bmj.e7913.
   PubMed Web of Science ®Google Scholar
• Sex steroid treatment for pubertal induction and replacement in the adolescent girl: Royal college of obstetricians and gynaecologists – scientific impact paper. 2013. Available at https://www.rcog.org.uk/en/guidelines-research-services/guidelines/sip40/ (last accessed 24/7/2018).
   Google Scholar
• Karunaratna AMDS, Ranasingha JGS, Mudiyanse RM. Iron overload in beta thalassemia major patients. Int J Blood Transfus Immunohematol 2017;7:33–40. doi: 10.5348/ijbti-2017-32-OA-5
   Google Scholar
• Chandrashekar V. Hb A1c separation by high performance liquid chromatography in hemoglobinopathies. Scientifica (Cairo). 2016. doi: 10.1155/2016/2698362
   PubMed Web of Science ®Google Scholar
• Fawzy MS, Toraih EA, Abdallah HY. Long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1): A molecular Predictor of Poor survival in Glioblastoma Multiforme in Egyptian patients. Egypt J Medical Human Genet. 2017;18:1–239. doi:10.1016/j.ejmhg.2016.08.003.
   Google Scholar
• Bustin SA, Benes V, Garson JA, et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem. 2009;55:11–622. doi:10.1373/clinchem.2008.112797.
   Web of Science ®Google Scholar
• Bustin SA, Benes V, Garson J, et al. The need for transparency and good practices in the qPCR literature. Nat Methods. 2013;10:1063–1067. doi:10.1038/nmeth.2697.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2−△△CT method. Methods. 2001;25:402–408. doi:10.1006/meth.2001.1262.
   PubMed Web of Science ®Google Scholar
• Kyriakou A. Skordis N. Mediterr J Hematol Infect Dis. 2009;1; doi:10.4084/MJHID.2009.003.
   PubMedGoogle Scholar
• Lelli A, Nolan KA, Santambrogio S, et al. Induction of long non coding RNA MALAT1 in hypoxic mice. Hypoxia (Auckl). 2015;3:45–52. doi:10.2147/HP.S90555.
   PubMed Web of Science ®Google Scholar
• Tripathi V, Shen Z, Chakraborty A, et al. Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet. 2013;9; doi:10.1371/journal.pgen.1003368.
   PubMed Web of Science ®Google Scholar
• Chen R, Liu Y, Zhuang H, et al. Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation. Nucleic Acids Res. 2017;45:9947–9959. doi:10.1093/nar/gkx600.
   PubMed Web of Science ®Google Scholar
• Ekwattanakit S, Siritanaratkul N, Viprakasit V. A prospective analysis for prevalence of complications in Thai non-transfusion-dependent Hb E/β-thalassemia and α-thalassemia (Hb H disease). Am J Hematol. 2018;93:623–629. doi:10.1002/ajh.25046.
   PubMed Web of Science ®Google Scholar
• Galanello R., Origa R. Beta-thalassemia. Orphanet J Rare Dis. 2010;5:11. doi: 10.1186/1750-1172-5-11
   PubMed Web of Science ®Google Scholar
• Danjou F, Anni F, Perseu L, et al. Genetic modifiers of β-thalassemia and clinical severity as assessed by age at first transfusion. Haematologica. 2012;97:989–993. doi:10.3324/haematol.2011.053504.
   PubMed Web of Science ®Google Scholar
• Danjou F, Francavilla M, Anni F, et al. A genetic score for the prediction of beta-thalassemia severity. Haematologica. 2015;100:452–457. doi:10.3324/haematol.2014.113886.
   PubMed Web of Science ®Google Scholar
• Rund D, Beta-Thalassemia RE. N Engl J Med. 2005;353:1135–1146. doi:10.1056/NEJMra050436.
   PubMed Web of Science ®Google Scholar
• Sun C, Huang L, Li Z, et al. Long non-coding RNA MIAT in development and disease: a new player in an old game. J Biomed Sci. 2018;25:23), doi:10.1186/s12929-018-0427-3.
   PubMed Web of Science ®Google Scholar
• Sheik MJ, Gaughwin PM, Lim B, et al. Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA. 2010;16:324–337. doi:10.1261/rna.
   PubMed Web of Science ®Google Scholar
• Stoyanova E, Trudel M, Felfly H, et al. Vascular endothelial dysfunction in β-thalassemia occurs Despite increased eNOS expression and Preserved vascular Smooth muscle cell Reactivity to NO. PLoS ONE. 2012;7; doi:10.1371/journal.pone.0038089.
   Web of Science ®Google Scholar
• Butthep P, Rummavas S, Wisedpanichkij R, et al. Increased circulating activated endothelial cells, vascular endothelial growth factor, and tumor necrosis factor in thalassemia. Am J Hematol. 2002;70:100–106. doi:10.1002/ajh.10101.
   PubMed Web of Science ®Google Scholar
• Aessopos A, Farmakis D, Deftereos S, et al. Thalassemia heart disease: a comparative evaluation of thalassemia major and thalassemia intermedia. Chest. 2005;127:1523–1530. doi:10.1378/chest.127.5.1523.
   PubMed Web of Science ®Google Scholar
• Pourfarzad F, von Lindern M, Azarkeivan A, et al. Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity. Haematologica. 2013;98:696–704. doi:10.3324/haematol.2012.074492.
   PubMed Web of Science ®Google Scholar