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Hematology Volume 26, 2021 - Issue 1
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Case Report

A case of a patient characterized by t(8;22)(p11;q11) and BCR/FGFR1 fusion gene, who was successfully treated with haploidentical hematopoietic stem cell transplantation

Xin Chena People’s Hospital of Shenzhen Baoan District, Shenzhen, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-3896-1651
ORCID Icon,
Lifang Huangb Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China
,
Caifeng Zhenga People’s Hospital of Shenzhen Baoan District, Shenzhen, People’s Republic of China
&
Zhiqiong Wangb Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of ChinaCorrespondence[email protected]
Pages 691-696 | Published online: 07 Sep 2021

References

  • Demiroglu A, Steer EJ , Heath C, et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood 2001;98(13):3778–3783.
  • Fioretos T, Panagopoulos I , Lassen C, et al. Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL. Genes, Chromosomes Cancer 2001;32(4):302–310.
  • Pini M, Gottardi E, Scaravaglio P, et al. A fourth case of BCR-FGFR1 positive CML-like disease with t(8;22) translocation showing an extensive deletion on the derivative chromosome 8p. Hematol J 2002;3(6):315–316.
  • Murati A, Arnoulet C, Lafage-Pochitaloff M, et al. Dual lympho-myeloproliferative disorder in a patient with t(8;22) with BCR-FGFR1 gene fusion. Int J Oncol 2005;26(6):1485–1492.
  • Richebourg S, Theisen O, Plantier I, et al. Chronic myeloproliferative disorder with t(8;22)(p11;q11) can mime clonal cytogenetic evolution of authentic chronic myelogeneous leukemia. Genes, Chromosomes Cancer 2008;47(10):915–918.
  • Khodadoust MS, Luo B, Medeiros BC, et al. Clinical activity of ponatinib in a patient with FGFR1-rearranged mixed-phenotype acute leukemia. Leukemia 2016;30(4):947–950.
  • Macdonald D, Aguiar RC, Mason P, et al. A new myeloproliferative disorder associated with chromosomal translocations involving 8p11: a review. Leukemia 1995;9(10):1628–1630.
  • Jackson CC, Medeiros LJ, Miranda RN. 8p11 myeloproliferative syndrome: a review. Hum Pathol 2010;41(4):461–476.
  • Sabattini E, Bacci F, Sagramoso C, et al. WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview. Pathologica 2010;102(3):83–87.
  • Baldazzi C, Iacobucci I, Luatti S, et al. B-cell acute lymphoblastic leukemia as evolution of a 8p11 myeloproliferative syndrome with t(8;22)(p11;q11) and BCR-FGFR1 fusion gene. Leuk Res 2010;34(10):e282–e285.
  • Montenegro-Garreaud X, Miranda RN, Reynolds A, et al. Myeloproliferative neoplasms with t(8;22)(p11.2;q11.2)/BCR-FGFR1: a meta-analysis of 20 cases shows cytogenetic progression with B-lymphoid blast phase. Hum Pathol 2017;65:147–156.
  • Antic DA, Vukovic VM, Milosevic Feenstra JD, et al. 8p11 myeloproliferative syndrome: diagnostic challenges and pitfalls. J Buon 2016;21(3):745–749.
  • Qin YW, Yang YN, Bai P, et al. Chronic myelogenous leukemia-like hematological malignancy with t(8;22) in a 26-year-old pregnant woman: a case report. Oncol Lett 2016;11(6):4131–4133.
  • Liu JJ, Meng L. 8p11 myeloproliferative syndrome with t(8;22)(p11;q11): a case report. Exp Ther Med 2018;16(2):1449–1453.
  • Chase A, Bryant C, Score J, et al. Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome. Haematologica 2013;98(1):103–106.
  • Landberg N, Dreimane A, Rissle M, et al. Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib. Eur J Haematol 2017;99(5):442–448.
  • Khodadoust MS, Luo B, Medeiros BC, et al. Clinical activity of ponatinib in a patient with FGFR1-rearranged mixed-phenotype acute leukemia. Leukemia 2016;30(4):947–950.
  • Konishi Y, Kondo T, Nakao K, et al. Allogeneic hematopoietic stem cell transplantation for 8p11 myeloproliferative syndrome with BCR-FGFR1 gene rearrangement: a case report and literature review. Bone Marrow Transplant 2018;54:326–329.
  • Morishige S, Oku E, Takata Y, et al. A case of 8p11 myeloproliferative syndrome with BCR-FGFR1 gene fusion presenting with trilineage acute leukemia/lymphoma, successfully treated by cord blood transplantation. Acta Haematol 2013;129(2):83–89.
  • Lv M, Chang Y, Huang X. Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem cell transplantation. Front Med 2018;54:45–56.
  • Xu L, Chen H, Chen J, et al. The consensus on indications, conditioning regimen, and donor selection of allogeneic hematopoietic cell transplantation for hematological diseases in China-recommendations from the Chinese society of hematology. J Hematol Oncol 2018;11(1):33.
  • Dholaria B, Savani BN, Labopin M, et al. Clinical applications of donor lymphocyte infusion from an HLAhaploidentical donor: consensus recommendations from the acute leukemia working party of the EBMT. Haematologica 2020;105(1):47–58.

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