Polymorphisms of inflammation-related genes and susceptibility to childhood leukemia: evidence from a meta-analysis of 16 published studies

References

• Sharma R. A systematic examination of burden of childhood cancers in 183 countries: estimates from GLOBOCAN 2018. Eur J Cancer Care (Engl). 2021;30(5):e13438.
   PubMed Web of Science ®Google Scholar
• Dufort YAG, Castiglioni M, Pagés C, et al. Treatment of childhood acute myeloid leukemia in Uruguay: results of 2 consecutive protocols over 20 years. J Pediatr Hematol. 2020;42(5):359–366.
   PubMed Web of Science ®Google Scholar
• Gottschalk Højfeldt S, Grell K, Abrahamsson J, et al. Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia. Blood. 2021;137(17):2373–2382.
   PubMed Web of Science ®Google Scholar
• Eckert C, Parker C, Moorman AV, et al. Risk factors and outcomes in children with high-risk B-cell precursor and T-cell relapsed acute lymphoblastic leukaemia: combined analysis of ALLR3 and ALL-REZ BFM 2002 clinical trials. Eur J Cancer. 2021;151:175–189.
   PubMed Web of Science ®Google Scholar
• Bloom M, Maciaszek JL, Clark ME, et al. Recent advances in genetic predisposition to pediatric acute lymphoblastic leukemia. Expert Rev Hematol. 2020;13(1):55–70.
   PubMed Web of Science ®Google Scholar
• Gutierrez-Camino A, Martin-Guerrero I, García-Orad A. Genetic susceptibility in childhood acute lymphoblastic leukemia. Med Oncol. 2017;34(10):179.
   PubMed Web of Science ®Google Scholar
• Urwanisch L, Luciano M, Horejs-Hoeck J. The NLRP3 inflammasome and Its role in the pathogenicity of leukemia. Int J Mol Sci. 2021;22(3):1271.
   PubMed Web of Science ®Google Scholar
• Pérez-Figueroa E, Sánchez-Cuaxospa M, Martínez-Soto KA, et al. Strong inflammatory response and Th1-polarization profile in children with acute lymphoblastic leukemia without apparent infection. Oncol Rep. 2016;35(5):2699–2706.
   PubMed Web of Science ®Google Scholar
• Latoch E, Konończuk K, Konstantynowicz-Nowicka K, et al. Asymptomatic survivors of childhood acute lymphoblastic leukemia demonstrate a biological profile of inflamm-aging early in life. Cancers (Basel). 2022;14(10):2522.
   PubMed Web of Science ®Google Scholar
• Kaya Z, Yüce D, Kirkiz S, et al. Prognostic role of serum cytokines and soluble HLA-G levels in children with leukemia who undergo allogeneic stem cell transplantation. Cytokine. 2022;153:155869.
   PubMed Web of Science ®Google Scholar
• Sharaf-Eldein M, Elghannam D, Elderiny W, et al. Prognostic implication of MIF gene expression in childhood acute lymphoblastic leukemia. Clin Lab. 2018;64(9):1429–1437.
   PubMed Web of Science ®Google Scholar
• Stevens AM, Horton TM, Glasser CL, et al. IL-10 and TNFα are associated with decreased survival in low-risk pediatric acute myeloid leukemia; a children's oncology group report. Pediatr Hematol Oncol. 2023;40(2):147–158.
   PubMed Web of Science ®Google Scholar
• Ribeiro D, Melão A, van Boxtel R, et al. STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells. Blood Adv. 2018;2(17):2199–2213.
   PubMed Web of Science ®Google Scholar
• Xu Y, Mou J, Wang Y, et al. Regulatory T cells promote the stemness of leukemia stem cells through IL10 cytokine-related signaling pathway. Leukemia. 2022;36(2):403–415.
   PubMed Web of Science ®Google Scholar
• Alves FS, Xabregas LA, Kerr MWA, et al. Genetic polymorphisms of inflammasome genes associated with pediatric acute lymphoblastic leukemia and clinical prognosis in the Brazilian Amazon. Sci Rep. 2021;11(1):9869.
   PubMed Web of Science ®Google Scholar
• Lo WJ, Chang WS, Hsu HF, et al. Significant Association of Interleukin-10 Polymorphisms with Childhood Leukemia Susceptibility in Taiwan. In vivo. 2016;30(3):265–269.
   PubMed Web of Science ®Google Scholar
• Bonaventure A, Orsi L, Rudant J, et al. Genetic polymorphisms of Th2 interleukins, history of asthma or eczema and childhood acute lymphoid leukaemia: Findings from the ESCALE study (SFCE). Cancer Epidemiol. 2018;55:96–103.
   PubMed Web of Science ®Google Scholar
• Ji H, Li F, Song L, et al. Inflammation-related gene polymorphisms associated With childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2023;45(1):e9–e13.
   PubMed Web of Science ®Google Scholar
• Ajrouche R, Chandab G, Petit A, et al. Allergies, genetic polymorphisms of Th2 interleukins, and childhood acute lymphoblastic leukemia: The ESTELLE study. Pediatr Blood Cancer. 2022;69(3):e29402.
   PubMed Web of Science ®Google Scholar
• Lo CK, Mertz D, Loeb M. Newcastle-Ottawa Scale: comparing reviewers’ to authors’ assessments. BMC Med Res Methodol. 2014;14:45.
   PubMed Web of Science ®Google Scholar
• Winkler B, Taschik J, Haubitz I, et al. TGFβ and IL10 have an impact on risk group and prognosis in childhood ALL. Pediatr Blood Cancer. 2015;62(1):72–79.
   PubMed Web of Science ®Google Scholar
• de Lourdes Perim A, Guembarovski RL, Oda JM, et al. CXCL12 and TP53 genetic polymorphisms as markers of susceptibility in a Brazilian children population with acute lymphoblastic leukemia (ALL). Mol Biol Rep. 2013;40(7):4591–4596.
   PubMed Web of Science ®Google Scholar
• Xabregas LA, Hanna FSA, Magalhães-Gama F, et al. Association of Toll-like receptors polymorphisms with the risk of acute lymphoblastic leukemia in the Brazilian Amazon. Sci Rep. 2022;12(1):15159.
   PubMed Web of Science ®Google Scholar
• Miedema KG, Tissing WJ, Poele T, et al. Polymorphisms in the TLR6 gene associated with the inverse association between childhood acute lymphoblastic leukemia and atopic disease. Leukemia. 2012;26(6):1203–1210.
   PubMed Web of Science ®Google Scholar
• Kampouraki E, Lourou M, Zervou MI, et al. Role of CXCL12, TP53 and CYP1A1 gene polymorphisms in susceptibility to pediatric acute lymphoblastic leukemia. Oncol Lett. 2021;22(3):659.
   PubMed Web of Science ®Google Scholar
• Hiroki CH, Amarante MK, Petenuci DL, et al. IL-10 gene polymorphism and influence of chemotherapy on cytokine plasma levels in childhood acute lymphoblastic leukemia patients. Blood Cells Mol Dis. 2015;55(2):168–172.
   PubMed Web of Science ®Google Scholar
• Xue Y, Xu H, Rong L, et al. The MIF −173G/C polymorphism and risk of childhood acute lymphoblastic leukemia in a Chinese population. Leuk Res. 2010;34(10):1282–1286.
   PubMed Web of Science ®Google Scholar
• Sharaf-Eldein M, Elghannam D, Abdel-Malak C. MIF-173G/C (rs755622) polymorphism as a risk factor for acute lymphoblastic leukemia development in children. J Gene Med. 2018;20(9):e3044.
   PubMed Web of Science ®Google Scholar
• Stanulla M, Schrauder A, Welte K, et al. Tumor necrosis factor and lymphotoxin-alpha genetic polymorphisms and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study of patients treated with BFM therapy. BMC Blood Disord. 2001;1(1):2.
   PubMedGoogle Scholar
• Lauten M, Matthias T, Stanulla M, et al. Association of initial response to prednisone treatment in childhood acute lymphoblastic leukaemia and polymorphisms within the tumour necrosis factor and the interleukin-10 genes. Leukemia. 2002;16(8):1437–1442.
   PubMed Web of Science ®Google Scholar
• Ziino O, D'Urbano LE, De Benedetti F, et al. The MIF-173G/C polymorphism does not contribute to prednisone poor response in vivo in childhood acute lymphoblastic leukemia. Leukemia. 2005;19(12):2346–2347.
   PubMed Web of Science ®Google Scholar
• Ajrouche R, Chandab G, Petit A, et al. Allergies, genetic polymorphisms of Th2 interleukins, and childhood acute lymphoblastic leukemia: The ESTELLE study. Pediatr Blood Cancer. 2022;69(3):e29402.
   PubMed Web of Science ®Google Scholar
• Ahadi HR, Sadrabadi AE, Jalili A, et al. Association of Interleukin 10 (IL-10) Gene Polymorphism (819 T > C) with Susceptibility to Acute Myeloid Leukemia: A Meta-Analysis. Iran J Public Health. 2022;51(1):19–26.
   PubMed Web of Science ®Google Scholar
• Hong P, Feng WY, Fu LH, et al. Associations between genetic polymorphisms in interleukin-10 and hematological oncology: evidence from a meta-analysis. Cancer Biol Ther. 2020;21(4):372–378.
   PubMed Web of Science ®Google Scholar
• Gao S, Tang K, Chen J, et al. The single nucleotide polymorphisms of interleukin-10 are associated with the risk of leukaemia: Evidence from 18 case-control studies. Medicine (Baltimore). 2020;99(44):e22929.
   PubMed Web of Science ®Google Scholar
• Kumari R, Kumar S, Ahmad MK, et al. Promoter variants of TNF-α rs1800629 and IL-10 rs1800871 are independently associated with the susceptibility of coronary artery disease in north Indian. Cytokine. 2018;110:131–136.
   PubMed Web of Science ®Google Scholar
• Xia L, Chen M, Bi D, et al. Combined analysis of interleukin-10 gene polymorphisms and protein expression in children With cerebral palsy. Front Neurol. 2018;9:182.
   PubMed Web of Science ®Google Scholar
• Zidi S, Gazouani E, Stayoussef M, et al. IL-10 gene promoter and intron polymorphisms as genetic biomarkers of cervical cancer susceptibility among Tunisians. Cytokine. 2015;76(2):343–347.
   PubMed Web of Science ®Google Scholar
• Palivonaite M, Gedvilaite G, Glebauskiene B, et al. IL-10 gene Rs1800871, Rs1800872, and Rs1800896 polymorphisms and IL-10 serum levels association with pituitary adenoma. Biomedicines. 2022;10(8):1921.
   PubMed Web of Science ®Google Scholar
• Berti FCB, Pereira APL, Trugilo KP, et al. IL-10 gene polymorphism c.−592C > A increases HPV infection susceptibility and influences IL-10 levels in HPV infected women. Infect Genet Evol. 2017;53:128–134.
   PubMed Web of Science ®Google Scholar
• Bien E, Balcerska A, Adamkiewicz-Drozynska E, et al. Pre-treatment serum levels of interleukin-10, interleukin-12 and their ratio predict response to therapy and probability of event-free and overall survival in childhood soft tissue sarcomas, Hodgkin's lymphomas and acute lymphoblastic leukemias. Clin Biochem. 2009;42(10-11):1144–1157.
   PubMed Web of Science ®Google Scholar
• Nishioka C, Ikezoe T, Yang J, et al. CD82 regulates STAT5/IL-10 and supports survival of acute myelogenous leukemia cells. Int J Cancer. 2014;134(1):55–64.
   PubMed Web of Science ®Google Scholar
• El Hajj H, Hleihel R, El Sabban M, et al. Loss of interleukin-10 activates innate immunity to eradicate adult T-cell leukemia-initiating cells. Haematologica. 2021;106(5):1443–1456.
   PubMed Web of Science ®Google Scholar
• Zhang X, Fan Y, Li Z. SDF1-3'A polymorphism is associated with increased risk of hematological malignancy: a meta-analysis. Onco Targets Ther. 2017;10:1575–1583.
   PubMed Web of Science ®Google Scholar
• Tong X, Ma Y, Deng H, et al. The SDF-1 rs1801157 Polymorphism is Associated with Cancer Risk: An Update Pooled Analysis and FPRP Test of 17,876 Participants. Sci Rep. 2016;6:27466.
   PubMed Web of Science ®Google Scholar
• Garcia-Moruja C, Rueda P, Torres C, et al. Molecular phenotype of CXCL12beta 3'UTR G801A polymorphism (rs1801157) associated to HIV-1 disease progression. Curr HIV Res. 2009;7(4):384–389.
   PubMed Web of Science ®Google Scholar
• Mowafi F, Cagigi A, Matskova L, et al. Chemokine CXCL12 enhances proliferation in pre-B-ALL via STAT5 activation. Pediatr Blood Cancer. 2008;50(4):812–817.
   PubMed Web of Science ®Google Scholar
• Cui XY, Tjønnfjord GE, Kanse SM, et al. Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia. Sci Rep. 2021;11(1):5127.
   PubMed Web of Science ®Google Scholar
• Shey MS, Randhawa AK, Bowmaker M, et al. Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion. Genes Immun. 2010;11(7):561–572.
   PubMed Web of Science ®Google Scholar
• Donn R, Alourfi Z, Benedetti FD, et al. Mutation screening of the macrophage migration inhibitory factor gene: Positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis. Arthritis Rheum. 2002;46(9):2402–2409.
   PubMedGoogle Scholar
• Abdul-Aziz AM, Shafat MS, Mehta TK, et al. MIF-Induced stromal PKCβ/IL8 Is essential in human acute myeloid leukemia. Cancer Res. 2017;77(2):303–311.
   PubMed Web of Science ®Google Scholar