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Research Article

Relationships of platelet glycoprotein specific antibody with therapeutic efficacy of short-term high-dose dexamethasone and bleeding score in the newly diagnosed adult patients with primary immune thrombocytopenia

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Article: 2255801 | Received 15 Jul 2023, Accepted 01 Sep 2023, Published online: 13 Sep 2023

References

  • Liu XG, Bai XC, Chen FP, et al. Chinese guidelines for treatment of adult primary immune thrombocytopenia. Int J Hematol. 2018;107:615–623. doi:10.1007/s12185-018-2445-z
  • Cooper N, Ghanima W. Immune thrombocytopenia. N Engl J Med. 2019;381(10):945–955. doi:10.1056/NEJMcp1810479
  • Chen JF, Yang LH, Chang LX, et al. The clinical significance of circulating B cells secreting anti-glycoproteinIIb/IIIa antibody and platelet glycoprotein IIb/IIIa inpatients with primary immune thrombocytopenia. Hematology. 2012;17(5):283–290. doi:10.1179/1607845412Y.0000000014
  • Frederiksen H, Maegbaek ML, Nørgaard M. Twenty-year mortality of adult patients with primary immune thrombocytopenia: a Danish population-based cohort study. Br J Haematol. 2014;166(2):260–267. doi:10.1111/bjh.12869
  • Neunert C, Terrell DR, Arnold DM, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019;3(23):3829–3866. doi:10.1182/bloodadvances.2019000966
  • Wei Y, Ji XB, Wang YW, et al. High-dose dexamethasone vs prednisone for treatment of adult immune thrombocytopenia: a prospective multicenter randomized trial. Blood. 2016;127(3):296–302. quiz 370, doi:10.1182/blood-2015-07-659656
  • Thrombosis and Hemostasis Group. Chinese Society of Hematology, Chinese Medical Association. [Chinese guideline on the diagnosis and management of adult primary immune thrombocytopenia (version 2020)]. Zhonghua Xue Ye Xue Za Zhi. 2020;41(8):617–623. Chinese, doi:10.3760/cma.j.issn.0253-2727
  • Frederiksen H, Ghanima W. Response of first line treatment with corticosteroids in a population-based cohort of adults with primary immune thrombocytopenia. Eur J Intern Med. 2017;37:e23–e25. doi:10.1016/j.ejim.2016.09.001
  • Xu J, Zhang X, Feng S, et al. Clinical efficacy of high-dose dexamethasone with sequential prednisone maintenance therapy for newly diagnosed adult immune thrombocytopenia in a real-world setting. J Int Med Res. 2021;49(4):3000605211007322, doi:10.1177/03000605211007322
  • Khan AM, Mydra H, Nevarez A. Clinical practice updates in the management of immune thrombocytopenia. P T. 2017;42(12):756–763. PMID: 29234214.
  • Song F, Al-Samkari H. Management of adult patients with immune thrombocytopenia (ITP): a review on current guidance and experience from clinical practice. J Blood Med. 2021;12:653–664. doi:10.2147/JBM.S259101
  • Mishra K, Kumar S, Singh K, et al. Real-world experience of anti-D immunoglobulin in immune thrombocytopenia. Ann Hematol. 2022;101(6):1173–1179. doi:10.1007/s00277-022-04829-4
  • Mishra K, Kumar S, Jandial A, et al. Real-world experience of eltrombopag in immune thrombocytopenia. Am J Blood Res. 2020;10(5):240–251. PMID: 3322456.
  • Al-Samkari H, Rosovsky RP, Karp Leaf RS, et al. A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia. Blood Adv. 2020;4(1):9–18. doi:10.1182/bloodadvances.2019000868
  • Zhang J, Zhang Q, Li Y, et al. Immune dysregulation in primary immune thrombocytopenia patients. Hematology. 2018;23(8):510–516. doi:10.1080/10245332.2018.1435021
  • Caserta S, Zaccuri AM, Innao V, et al. Immune thrombocytopenia: options and new perspectives. Blood Coagul Fibrinolysis. 2021;32(7):427–433. doi:10.1097/MBC.0000000000001058
  • Cines DB, Bussel JB, Liebman HA, et al. The ITP syndrome: pathogenic and clinical diversity. Blood. 2009;113(26):6511–6521. doi:10.1182/blood-2009-01-129155
  • Chen Y, Hu J, Chen Y. Platelet desialylation and TFH cells-the novel pathway of immune thrombocytopenia. Exp Hematol Oncol. 2021;10(1):21, doi:10.1186/s40164-021-00214-5
  • Zheng SS, Ahmadi Z, Leung HHL, et al. Antiplatelet antibody predicts platelet desialylation and apoptosis in immune thrombocytopenia. Haematologica. 2022;107(9):2195–2205. doi:10.3324/haematol.2021.279751
  • Sirotich E, Guyatt G, Gabe C, et al. Definition of a critical bleed in patients with immune thrombocytopenia: communication from the ISTH SSC subcommittee on platelet immunology. J Thromb Haemost. 2021;19(8):2082–2088. doi:10.1111/jth.15368
  • Hirokawa M, Fujishima N, Togashi M, et al. High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4-28/IGHJ4 gene in primary immune thrombocytopenia. Sci Rep. 2019;9(1):8645, doi:10.1038/s41598-019-45264-2
  • Lambert MP, Gernsheimer TB. Clinical updates in adult immune thrombocytopenia. Blood. 2017;129:2829–2835. doi:10.1182/blood-2017-03-754119
  • Zeng Q, Zhu L, Tao L, et al. Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies. Am J Hematol. 2012;87(2):206–208. doi:10.1002/ajh.22211
  • Peng J, Ma SH, Liu J, et al. Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study. J Thromb Haemost. 2014;12(4):497–504. doi:10.1111/jth.12524
  • Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood. 2009;113(11):2386–2393. doi:10.1182/blood-2008-07-162503
  • Provan D, Stasi R, Newland AC, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168–186. doi:10.1182/blood-2009-06-225565
  • Atkinson TM, Ryan SJ, Bennett AV, et al. The association between clinician-based common terminology criteria for adverse events (CTCAE) and patient-reported outcomes (PRO): a systematic review. Support Care Cancer. 2016;24:3669–3676. doi:10.1007/s00520-016-3297-9
  • Mishra K, Kumar S, Sandal R, et al. Safety and efficacy of splenectomy in immune thrombocytopenia. Am J Blood Res. 2021;11(4):361–372. PMID: 34540344.
  • Vianelli N, Auteri G, Buccisano F, et al. Refractory primary immune thrombocytopenia (ITP): current clinical challenges and therapeutic perspectives. Ann Hematol. 2022;101(5):963–978. doi:10.1007/s00277-022-04786-y
  • Terrell DR, Neunert CE, Cooper N, et al. Immune thrombocytopenia (ITP): current limitations in patient management. Medicina (Kaunas. 2020;56(12):667, doi:10.3390/medicina56120667
  • Provan D, Arnold DM, Bussel JB, et al. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019;3(22):3780–3817. doi:10.1182/bloodadvances.2019000812
  • Du Y, Yang C, Chen M, et al. Tacrolimus is effective in relapsed/refractory autoimmune cytopenias: results of a single-center retrospective study. Hematology. 2020;25(1):478–483. doi:10.1080/16078454.2020.1852763
  • Hou M, Peng J, Shi Y, et al. Mycophenolate mofetil (MMF) for the treatment of steroid-resistant idiopathic thrombocytopenic purpura. Eur J Haematol. 2003;70(6):353–357. doi:10.1034/j.1600-0609.2003.00076.x
  • George NP, Wei Q, Shin PK, et al. Staphylococcus aureus adhesion via Spa, ClfA, and SdrCDE to immobilized platelets demonstrates shear-dependent behavior. Arterioscler Thromb Vasc Biol. 2006;26(10):2394–2400. doi:10.1161/01.ATV.0000237606.90253.94
  • Fogarty PF, Segal JB. The epidemiology of immune thrombocytopenic purpura. Curr Opin Hematol. 2007;14(5):515–519. doi:10.1097/MOH.0b013e3282ab98c7
  • Cheng Y, Wong RS, Soo YO, et al. Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasone. N Engl J Med. 2003;349(23):831–836. doi:10.1056/NEJMoa.030254
  • Matschke J, Müller-Beissenhirtz H, Novotny J, et al. A randomized trial of daily prednisone versus pulsed dexamethasone in treatment-naïve adult patients with immune thrombocytopenia: EIS 2002 study. Acta Haematol. 2016;136(2):101–107. doi:10.1159/000445420
  • Liu X, Hou Y, Hou M. How we treat primary immune thrombocytopenia in adults. J Hematol Oncol. 2023;16(4), doi:10.1186/s13045-023-01401-z
  • Kuwana M, Okazaki Y, Kaburaki J, et al. Detection of circulating B cells secreting platelet-specific autoantibody is useful in the diagnosis of autoimmune thrombocytopenia. Am J Med. 2003;114(4):322–325. doi:10.1016/s0002-9343(02)01522-x
  • Nomura S, Yanabu M, Soga T, et al. Analysis of idiopathic thrombocytopenic purpura patients with antiglycoprotein IIb/IIIa or Ib autoantibodies. Acta Haematol. 1991;86(1):25–30. doi:10.1159/000204794
  • Scull CM, Hays WD, Fischer TH. Macrophage pro-inflammatory cytokine secretion is enhanced following interaction with autologous platelets. J Inflamm (Lond). 2010;7:53, doi:10.1186/1476-9255-7-53
  • Vollenberg R, Jouni R, Norris PAA, et al. Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia. Haematologica. 2019;104(6):1237–1243. doi:10.3324/haematol.2018.211086
  • Nieswandt B, Bergmeier W, Rackebrandt K, et al. Identification of critical antigen-specific mechanisms in the development of immune thrombocytopenic purpura in mice. Blood. 2000;96(7):2520–2527. PMID: 11001906. doi:10.1182/blood.V96.7.2520
  • Campbell K, Rishi K, Howkins G, et al. A modified rapid monoclonal antibody-specific immobilization of platelet antigen assay for the detection of human platelet antigen (HPA) antibodies: a multicenter evaluation. Vox Sang. 2007;93(4):289–297. doi:10.1111/j.1423-0410.2007.00989.x.
  • Grimaldi D, Canouï-Poitrine F, Croisille L, et al. Antiplatelet antibodies detected by the MAIPA assay in newly diagnosed immune thrombocytopenia are associated with chronic outcome and higher risk of bleeding. Ann Hematol. 2014;93(2):309–315. doi:10.1007/s00277-013-1855-5
  • Arnold DM, Santoso S, Greinacher A, et al. Recommendations for the implementation of platelet autoantibody testing in clinical trials of immune thrombocytopenia. J Thromb Haemost. 2012;10(4):695–697. doi:10.1111/j.1538-7836.2012.04664.x
  • Rodeghiero F, Marranconi E. Management of immune thrombocytopenia in women: current standards and special considerations. Expert Rev Hematol. 2020;13(2):175–185. doi:10.1080/17474086.2020.1711729