1,069
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Lymphocyte subpopulations: a potential predictor of a response in patients with immune thrombocytopenia

ORCID Icon, ORCID Icon, ORCID Icon, , , , , & ORCID Icon show all
Article: 2304486 | Received 25 Sep 2023, Accepted 04 Jan 2024, Published online: 22 Jan 2024

References

  • Neunert C, Terrell DR, Arnold DM, et al. American society of hematology 2019 guidelines for immune thrombocytopenia. Blood Advances. 2019;3:3829–3866. doi:10.1182/bloodadvances.2019000966
  • Yu L, Zhang C, Zhang L, et al. Biomarkers for immune thrombocytopenia. Biomark Res. 2015;3:19. doi:10.1186/s40364-015-0045-0
  • Cuker A, Prak E, Cines D. Can immune thrombocytopenia be cured with medical therapy? Semin Thromb Hemost. 2015;41:395–404. doi:10.1055/s-0034-1544001
  • Lozano ML, Mingot-Castellano ME, Perera MM, et al. Deciphering predictive factors for choice of thrombopoietin receptor agonist, treatment free responses, and thrombotic events in immune thrombocytopenia. Sci Rep. 2019;9:16680. doi:10.1038/s41598-019-53209-y
  • Kuter DJ, Newland A, Chong BH, et al. Romiplostim in adult patients with newly diagnosed or persistent immune thrombocytopenia (ITP) for up to 1 year and in those with chronic ITP for more than 1 year: a subgroup analysis of integrated data from completed romiplostim studies. Br J Haematol. 2019;185:503–513. doi:10.1111/bjh.15803
  • Cuker A, Liebman HA. Corticosteroid overuse in adults with immune thrombocytopenia: cause for concern. Res Pract Thromb Haemost. 2021;5; doi:10.1002/rth2.12592
  • Snell Taylor SJ, Nielson CM, Breskin A, et al. Effectiveness and safety of romiplostim among patients with newly diagnosed, persistent and chronic immune thrombocytopenia in European clinical practice. Adv Ther. 2021;38:2673–2688. doi:10.1007/s12325-021-01727-5
  • Arnold DM, Nazi I, Santos A, et al. Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura. Blood. 2010;115:29–31. doi:10.1182/blood-2009-06-222448
  • Zaja F, Vianelli N, Battista M, et al. Earlier administration of Rituximab allows higher rate of long-lasting response in adult patients with autoimmune thrombocytopenia. Exp Hematol. 2006;34:571–572. doi:10.1016/j.exphem.2006.02.009
  • Gudbrandsdottir S, Leven E, Imahiyerobo A, et al. Combination of thrombopoietin receptor agonists, immunosuppressants and intravenous immunoglobulin as treatment of severe refractory immune thrombocytopenia in adults and children. Br J Haematol. 2020;189; doi:10.1111/bjh.16426
  • Mahévas M, Gerfaud-Valentin M, Moulis G, et al. Characteristics, outcome, and response to therapy of multirefractory chronic immune thrombocytopenia. Blood. 2016;128:1625–1630. doi:10.1182/blood-2016-03-704734
  • Miltiadous O, Hou M, Bussel JB. Identifying and treating refractory ITP: difficulty in diagnosis and role of combination treatment. Blood. 2020;135:472–490. doi:10.1182/blood.2019003599
  • Bradbury CA, Pell J, Hill Q, et al. Mycophenolate Mofetil for first-line treatment of immune thrombocytopenia. N Engl J Med. 2021;385:885–895. doi:10.1056/NEJMoa2100596
  • Lin X, Xu A, Zhou L, et al. Imbalance of T lymphocyte subsets in adult immune thrombocytopenia. IJGM Volume. 2021;14:937–947. doi:10.2147/IJGM.S298888
  • Raphael I, Nalawade S, Eagar TN, et al. T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine. 2015;74:5–17. doi:10.1016/j.cyto.2014.09.011
  • Zhao Z, Yang L, Yang G, et al. Contributions of T lymphocyte abnormalities to therapeutic outcomes in newly diagnosed patients with immune thrombocytopenia. PLoS One. 2015;10:e0126601. doi:10.1371/journal.pone.0126601
  • Zhang J, Zhang Q, Li Y, et al. Immune dysregulation in primary immune thrombocytopenia patients. Hematology. 2018;23:510–516. doi:10.1080/10245332.2018.1435021
  • Rocha AMC, Souza C, Rocha GA, et al. The levels of IL-17A and of the cytokines involved in Th17 cell commitment are increased in patients with chronic immune thrombocytopenia. Haematologica. 2011;96:1560–1564. doi:10.3324/haematol.2011.046417
  • Rong W, Yan-xiang Z, Shan-shan X, et al. Lymphocyte subsets in primary immune thrombocytopenia. Blood Coagul Fibrinolysis. 2014;25:816–819. doi:10.1097/MBC.0000000000000155
  • Goubran H, Hart C, Othman I, et al. Flow cytometry and immune thrombocytopenic purpura. Transfus Apher Sci. 2018;57:800–803. doi:10.1016/j.transci.2018.10.018
  • Oka S, Ono K, Nohgawa M. Prediction of response to first-line therapy with ITP by flow cytometric analysis of bone marrow lymphocyte phenotypes. Int J Hematol. 2020;111:771–778. doi:10.1007/s12185-020-02847-4
  • Peng J, Ma S-H, Liu J, et al. Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study. J Thromb Haemost. 2014;12:497–504. doi:10.1111/jth.12524
  • Feng R, Liu X, Zhao Y, et al. GPIIb/IIIa autoantibody predicts better rituximab response in ITP. Br J Haematol. 2018;182:305–307. doi:10.1111/bjh.14782
  • Yu Y, Hou Y, Zhao Y, et al. Platelet autoantibody specificity and response to rhTPO treatment in patients with primary immune thrombocytopenia. Br J Haematol. 2021;194:191–194. doi:10.1111/bjh.17510
  • Beardsley MD, Ertem MD. Platelet autoantibodies in immune thrombocytopenic purpura. Transfus Sci. 1998;19:237–244. doi:10.1016/S0955-3886(98)00037-X
  • Mahévas M, Ebbo M, Audia S, et al. Efficacy and safety of rituximab given at 1,000 mg on days 1 and 15 compared to the standard regimen to treat adult immune thrombocytopenia. Am J Hematol. 2013;88:858–861. doi:10.1002/ajh.23518