Protective effects of minocycline and MDL 28170 in gentamicin ototoxicity

References

• Forge A, Schacht J. Aminoglycoside antibiotics. Audiol & Neuro-Otol. 2000; 5: 3–22
   PubMed Web of Science ®Google Scholar
• Tablan OC, Reyes MP, Rintelmann WF, Lerner AM. Renal and auditory toxicity of high-dose, prolonged therapy with gentamicin and tobramycin in Pseudomonas endocarditis. J Infect Dis. 1984; 149: 257–63
   PubMed Web of Science ®Google Scholar
• Hawkins JE. Drug ototoxicity. Handbook of Sensory Physiology, WD Keidel, WD Neff. Springer, Berlin 1976; 707–48
   Google Scholar
• Rüedi L, Furrer W, Graf K, Nager G, Tschirren B, Luthy F. Nouvelles constatations sur la toxicité de la streptomycine et de la quinine à l'egard de l'oreille du cobaye. Rev Laryngol. 1951; 72: 238–64
   PubMedGoogle Scholar
• Rüedi L, Furrer W, Luthy F, Nager G, Tschirren B. Further observations concerning the toxic effects of streptomycin and quinine on the auditory organ of guinea pig. Laryngoscope 1952; 62: 333–57
   PubMed Web of Science ®Google Scholar
• Hawkins JE. Ototoxic mechanisms: a working hypothesis. Audiology 1973; 12: 383–93
   PubMedGoogle Scholar
• Johnsson LG, Hawkins JE, Kingsley TC, Black FO, Matz GJ. Aminoglycoside-induced cochlear pathology in man. Acta Otolaryngol. 1981; 383: 1–19
   Google Scholar
• Sha SH, Schacht J. Salicylate attenuates gentamicin-induced ototoxicity. Lab Invest. 1999; 79: 807–81
   PubMed Web of Science ®Google Scholar
• Satoh T, Enokido Y, Kubo T, Yamada M, Hatanaka H. Oxygen toxicity induces apoptosis in neuronal cells. Cell Mol Neurobiol. 1998; 18: 649–66
   PubMedGoogle Scholar
• Pierson MJ, Moller AR. Prophylaxis of kanamycin-induced ototoxicity by a radioprotectant. Hear Res. 1981; 4: 79–87
   PubMed Web of Science ®Google Scholar
• Garetz SL, Altschuler RA, Schacht J. Attenuation of gentamicin ototoxicity by glutathione in the guinea pig in vivo. Hear Res. 1994; 77: 81–7
   PubMed Web of Science ®Google Scholar
• Bertolaso L, Bindini D, Previati M, Falgione D, Lanzoni I, Parmeggiani A, et al. Gentamicin-induced cytotoxicity involves protein kinase c activation, glutathione extrusion and malondialdehyde production in an immortalized cell line from the organ of Corti. Audiol & Neurootol. 2003; 8: 38–48
   PubMed Web of Science ®Google Scholar
• Clerici WJ, Hensley K, DiMartino DL, Butterfield DA. Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants. Hear Res. 1996; 98: 116–24
   PubMed Web of Science ®Google Scholar
• Wang KKW, Nath R, Raser KJ, Hajimohammadreza I. Maitotoxin induces calpain activation in SH-SY5Y neuroblastoma cells and cerebrocortical cultures. Arch Biochem Biophys. 1996; 331: 208–14
   PubMedGoogle Scholar
• Dulon D, Zajic G, Aran JM, Schacht J. Aminoglycoside antibiotics impair calcium entry but not viability and motility in isolated cochlear outer hair cells. J Neurosci Res. 1989; 24: 338–46
   PubMed Web of Science ®Google Scholar
• Brown AM, McDowell B, Forge A. Acoustic distortion products can be used to monitor the effects of chronic gentamicin treatment. Hear Res. 1989; 42: 143–56
   PubMed Web of Science ®Google Scholar
• Li L, Forge A. Cultured explants of the vestibular sensory epithelia from adult guinea pigs and effects of gentamicin: a model for examination of hair cell loss and epithelial repair mechanism. Aud Neurosci. 1995; 1: 111–25
   Google Scholar
• Nakagawa T, Yamane H, Takayama M, Sunami K, Nakai Y. Apoptosis of guinea pig cochlear hair cells following chronic aminoglycoside treatment. Eur Arch Otorhinolaryngol. 1998; 255: 127–31
   PubMedGoogle Scholar
• Pörn-Ares MI, Ares MPS, Orrenius S. Calcium signalling and the regulation of apoptosis. Toxicology in vitro 1998; 12: 539–43
   PubMedGoogle Scholar
• Wood DE, Newcomb EW. Caspase-dependent activation of calpain during drug-induced apoptosis. J Biol Chem. 1999; 274: 8309–15
   PubMed Web of Science ®Google Scholar
• Jung BJ, Jung YK. Calpeptin suppresses tumour necrosis factor-α-induced death and accumulation of p53 in L929 mouse sarcoma cells. Apoptosis 2002; 7: 115–21
   PubMedGoogle Scholar
• Ruiz-Vela A, Gonzalez de Buitrago G, Martinez AC. Implication of calpain in caspase activation during B-cell clonal deletion. EMBO J. 1999; 18: 4988–98
   PubMed Web of Science ®Google Scholar
• Nakagawa T, Yuan J. Cross-talk between two cysteine protease families: activation of caspase-12 by calpain in apoptosis. J Cell Biol. 2000; 150: 887–94
   PubMed Web of Science ®Google Scholar
• Lanzoni I, Corbacella E, Ding D, Previati M, Salvi R. MDL 28170 attenuates gentamicin ototoxicity. Audiol Med. 2005; 3: 82–9
   Google Scholar
• Perrin BJ, Huttenlocher A. Molecules in focus calpain. Intern J Biochem & Cell Biol. 2002; 34: 722–5
   PubMed Web of Science ®Google Scholar
• Sorimachi H, Ishiura S, Suzuki K. Structure and physiological function of calpains. Biochem J. 1997; 328: 721–32
   PubMed Web of Science ®Google Scholar
• Saito K, Elce JS, Hamos JE, Nixon RA. Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer's disease: a potential molecular basis for neuronal degeneration. Proc Nat Acad Sci. USA 1993; 90: 2628–32
   PubMed Web of Science ®Google Scholar
• Stracher A. Calpain inhibitors as neuroprotective agents in neurodegenerative disorders. Intern Tinnitus J. 1997; 3: 71–5
   PubMedGoogle Scholar
• Saatman KE, Murai H, Bartus RT, Smith DH, Hayward NJ, Perri BR, McIntosh TK. Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat. Proc Nat Acad Sci. USA 1996; 93: 3428–33
   PubMed Web of Science ®Google Scholar
• Nath R, Raser KJ, McGinnis K, Nadimpalli R, Stafford D, Wang KK. Effects of ICE-like protease and calpain inhibitors on neuronal apoptosis. Neuroreport 1996; 8: 249–55
   PubMed Web of Science ®Google Scholar
• Jordan J, Galindo MF, Miller RJ. Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture. J Neurochem. 1997; 68: 1612–21
   PubMed Web of Science ®Google Scholar
• Ray Swapan K, Hogan Edward L, Banik Naren L. Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors. Brain Res Rev. 2003; 42: 169–85
   PubMedGoogle Scholar
• Squier MKT, Cohen JJ. Calpain, an upstream regulator of thymocyte apoptosis. J Immunol. 1997; 158: 3690–7
   PubMed Web of Science ®Google Scholar
• Cheng AG, Huang T, Stracher A, Kim A, Liu W, Malgrange B, et al. Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis. Brain Res. 1999; 850: 234–43
   PubMed Web of Science ®Google Scholar
• Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309–12
   PubMed Web of Science ®Google Scholar
• Seshagiri S, Miller LK. Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis. Curr Biol. 1997; 7: 455–60
   PubMed Web of Science ®Google Scholar
• Gorman AM, Orrenius S, Ceccatelli S. Apoptosis in neuronal cells: role of caspases. Neurorep. 1998; 9: 49–55
   PubMed Web of Science ®Google Scholar
• Antonsson B, Martinou JC. The Bcl-2 protein family. Exp Cell Res. 2000; 256: 50–7
   PubMed Web of Science ®Google Scholar
• Colovic M, Caccia S. Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat. J Chromatogr B Analyt Technol Biomed Life Sci. 2003; 791: 337–43
   PubMed Web of Science ®Google Scholar
• Wei X, Zhao L, Liu J, Dodel RC, Farlow MR, Du Y. Minocycline prevents gentamicin-induced ototoxicity by inhibiting p38 MAP kinase phosphorylation and caspase 3 activation. Neuroscience 2005; 2: 513–21
   Google Scholar
• Bauer AW, Kirby WM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disc method. Am J Clin Path. 1966; 45: 493–6
   PubMed Web of Science ®Google Scholar
• Hashino E, Shero M, Salvi RJ. Lysosomal targeting and accumulation of aminoglycoside antibiotics in sensory hair cells. Brain Res. 1997; 777: 75–85
   PubMed Web of Science ®Google Scholar
• Löwenheim H, Kil J, Gültig K, Zenner HP. Determination of hair cell degeneration and hair cell death in neomycin treated cultures of the neonatal rat cochlea. Hear Res. 1999; 128: 16–26
   PubMed Web of Science ®Google Scholar
• Mather M, Rottenberg H. Polycations induce the release of soluble intermembrane mitochondrial proteins. Biochim Biophys Acta. 2001; 1503: 357–68
   PubMedGoogle Scholar
• Kromer G, Reed J. Mitochondrial control of cell death. Nat Med. 2000; 6: 513–9
   PubMedGoogle Scholar
• Loeffler M, Kroemer G. The mitochondrion in cell death control: certainties and incognita. Exp Cell Res. 2000; 256: 19–26
   PubMed Web of Science ®Google Scholar
• Liu W, Staecker H, Stupak H, Malgrange B, Lefebvre P, van der Water TR. Caspase inhibitors prevent cisplatin-induced apoptosis of auditory sensory cells. Neuroreport 1998; 9: 2609–14
   PubMed Web of Science ®Google Scholar
• Chen ZF, Schottler F, Lee KS. Neuronal recovery after moderate hypoxia is improved by the calpain inhibitor MDL28170. Brain Res. 1997; 769: 188–92
   PubMedGoogle Scholar
• Ding D, Stracher A, Salvi RJ. Leupeptin protects cochlear and vestibular hair cells from gentamicin ototoxicity. Hear Res. 2002; 164: 115–26
   PubMed Web of Science ®Google Scholar
• McCollum AT, Nasr P, Estus S. Calpain activates caspase-3 during UV-induced neuronal death but only calpain is necessary for death. J Neurochem. 2002; 82: 1208–20
   PubMed Web of Science ®Google Scholar
• Neumar RW, Xu YA, Gada H, Guttmann RP, Siman R. Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis. J Biol Chem. 2003; 278: 14162–7
   PubMed Web of Science ®Google Scholar
• Mehdi S. Cell-penetrating inhibitors of calpain. Trends Biochem Sci. 1999; 16: 150–3
   Google Scholar
• Boland B, Campbell V. β-amyloid(1–40)-induced apoptosis of cultured cortical neurons involves calpain-mediated cleavage of poly-ADP-ribose polymerase. Neurobiology of Aging 2003; 24: 179–86
   PubMedGoogle Scholar
• Citron M, Diehl TS, Gordon G, Biere AL, Seubert P, Selkoe DJ. Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities. Proc Natl Acad Sci. USA 1996; 93: 13170–5
   PubMed Web of Science ®Google Scholar