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Original

Pharmacological otoprotection strategies against cisplatin-induced ototoxicity

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Pages 154-159 | Published online: 11 Jul 2009

References

  • Weijl N, Hopman G, Wipkink-Bakker A, Lentjes E, Berger H, Cleton FJ, et al. Cisplatin combination chemotherapy induces a fall in plasma antioxidants of cancer patients. Ann Oncol. 1998; 9: 1331–7
  • Feghali J, Liu W, van de Water T. L-N-acetyl-cysteine protection against cisplatin-induced auditory neuronal and hair cell toxicity. Laryngoscope. 2001; 111: 1147–55
  • Kopke R, Liu W, Gabaizadeh R, Jacono A, Feghali J, Spray D, et al. Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells. Am J Otol. 1997; 18: 559–71
  • Rybak L, Ravi R, Somani S. Mechanism of protection by diethyldithiocarbamate against cisplatin ototoxicity: antioxidant system. Fundam Appl Toxicol. 1995; 26: 293–300
  • Cardinaal R, De Groot J, Huizing E, Veldman J, Smoorenburg G. Cisplatin-induced ototoxicity: morphological evidence of spontaneous outer hair cell recovery in albino guinea pigs?. Hear Res. 2000; 144: 147–56
  • Smoorenburg G, De Groot J, Hamers F, Klis S. Protection and spontaneous recovery from cisplatin-induced hearing loss. Ann N Y Acad Sci. 1999; 884: 192–210
  • van Ruijven M, De Groot J, Smoorenburg G. Time sequence of degeneration pattern in the guinea pig cochlea during cisplatin administration. A quantitative histological study. Hear Res. 2004; 197: 44–54
  • van Ruijven M, De Groot J, Klis S, Smoorenburg G. The cochlear targets of cisplatin: an electrophysiological and morphological time-sequence study. Hear Res. 2005; 205: 241–8
  • Usami S, Hjelle O, Ottersen O. Differential cellular distribution of glutathione: an endogenous antioxidant in the guinea pig inner ear. Brain Res. 1996; 743: 337–40
  • Sha SH, Taylor R, Forge A, Schacht J. Differential vulnerability of basal and apical hair cells is based on intrinsic susceptibility to free radicals. Hear Res. 2001; 155: 1–8
  • Jones M, Basinger M, Beaty J, Holscher M. The relative nephrotoxicity of cisplatin, cis-Pt (NH3)2(guanosine) 2 2+, and the hydrolysis product of cisplatin in the rat. Cancer Chemother Pharmacol. 1991; 29: 29–32
  • Ekborn A, Lindberg A, Laurell G, Wallin I, Eksborg S, Ehrsson H. Ototoxicity, nephrotoxicity and pharmacokinetics of cisplatin and its monohydrated complex in the guinea pig. Cancer Chemother Pharmacol. 2003; 51: 36–42
  • Hatzopoulos S, Di Stefano M, Albertin A, Martini A. Evaluation of cisplatin ototoxicity in a rat animal model. Ann N Y Acad Sci. 1999; 884: 211–25
  • Rybak L, Whitworth C. Ototoxicity: therapeutic opportunities. Drug Discov Today. 2005; 10: 1313–21
  • Geming L, Wei L, Dorothy F. Cisplatin ototoxicity to the rat inner ear: a role for HMG1 and iNOS. NeuroToxicology. 2006; 27: 22–30
  • Beneditti Panici P, Greggi S, Scambia G, Baiocchi G, Lomonaco M, Conti G, et al. Efficacy and toxicity of very high-dose cisplatin in advanced ovarian carcinoma: four-year survival analysis and neurological follow-up. Int J Gynecol Cancer. 1993; 3: 44–53
  • Clerici W, Hensley K, DiMartino D, Butterfield D. Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants. Hear Res. 1996; 98: 116–24
  • Gilbert D. Fifty years of radical ideas. Ann N Y Acad Sci. 2000; 899: 1–14
  • Evans P, Halliwell B. Micronutrients: oxidant/antioxidant status. Br J Nutr. 2001; 85(Suppl 2)S67–74
  • Rybak L, Husain K, Morris C, Whitworth C, Somani S. Effect of protective agents against cisplatin ototoxicity. Am J Otol. 2000; 21: 513–20
  • Behl C, Moosmann B. Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach. Free Rad Biol & Med. 2002; 33: 182–91
  • Neuwelt E, Pagel M, Hasler B, Deloughery T, Muldoon L. Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model. Cancer Res. 2001; 61: 7868–74
  • Lorito G, Giordano P, Prosser S, Martini A, Hatzopoulos S. Noise induced hearing loss: a study on pharmacological protection in the Sprague-Dawley rat with N-acetylcysteine. Acta Otorhinolaryncol Ital. 2006; 26: 133–9
  • Dickey D, Muldoon L, Kraemer D, Neuwelt E. Protection against cisplatin-induced ototoxicity by N-acetylcysteine in a rat model. Hear Res. 2004; 193: 25–30
  • Campbell K, Meech R, Rybak L, Hughes L. D-methionine protects against cisplatin damage to the stria vascularis. Hear Res. 1999; 138: 13–28
  • Campbell K, Meech R, Rybak L, Hughes L. The effect of D-methionine on cochlear oxidative state with and without cisplatin administration: mechanisms of otoprotection. J Am Acad Audiol. 2003; 14: 144–56
  • Giordano P, Lorito G, Ciorba A, Martini A, Hatzopoulos S. Protection against cisplatin ototoxicity in a Sprague-Dawley rat animal model. Acta Otorhinolarygol Ital. 2006; 26: 198–207
  • Teranishi M, Nakashima T, Wakabayashi T. Effects of alphatocopherol on cisplatin-induced ototoxicity in guinea pigs. Hear Res. 2001; 151: 61–70
  • Kalkanis J, Whitworth C, Rybak L. Vitamin E reduces cisplatin ototoxicity. Laryngoscope 2004; 114: 538–42
  • Hattori R, Inoue R, Sase K, Eizawa H, Kosuga K, Aoyama T, et al. Preferential inhibition of inducible nitric oxide synthase by ebselen. Eur J Pharmacol. 1994; 267: 1–2
  • Hoshida S, Aoki K, Nishida M, Yamashita N, Igarashi J, Hori M, et al. Effects of preconditioning with ebselen on glutathione metabolism and stress protein expression. J Pharmacol Exp Ther. 1997; 281: 1471–5
  • Lass A, Witting P, Stocker R, Esterbauer H. Inhibition of copper and peroxyl radical-induced LDL lipid oxidation by ebselen: antioxidant actions in addition to hydroperoxide-reducing activity. Biochim Biophys. 1996; 1303: 111–8
  • Muller A, Cardenas E, Graf P, Sies H. A novel biologically active seleno-organic compound-I. Biochem. Pharmacol. 1984; 33: 3225–9
  • Narayanaswami V, Sies H. Oxidative damage to mitochondria and protection by ebselen and other antioxidants. Biochem Pharmacol. 1990; 40: 1623–9
  • Schewe T. Molecular actions of ebselen – an anti-inflammatory antioxidant. Gen Pharmacol. 1995; 26: 1153–69
  • Lynch E, Gu R, Pierce C, Kil J. Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen. Hear Res. 2005; 201: 81–9
  • Schweitzer V. Cisplatin-induced ototoxicity: the effect of pigmentation and inhibitory agents. Laryngoscope. 1993; 103: 1–52
  • Treskes M, Nijtmans L, Fichtinger-Schepman A, van der Vijgh W. Effects of the modulating agent WR2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro compared to the effects of thiosulphate and diethyldithiocarbamate. Biochem Pharmacol. 1992; 43: 1013–9
  • Lempers E, Reedijk J. Reversibility of cisplatinmethionine in proteins by diethyldithiocarbamate or thiourea: a study with model adducts. Inorgan. Chem. 1990; 29: 217–22
  • Ekborn A, Laurell G, Johnstrom P, Wallin I, Eksborg S, Ehrsson H. D-methionine and cisplatin ototoxicity in the guinea pig: D-methionine influences cisplatin pharmacokinetics. Hear Res. 2002; 165: 53–61
  • Heudi O, Cailleaux A, Allain P. Kinetic studies of the reactivity between cisplatin and its monoaquo species with L-methionine. J Inorg Biochem. 1998; 71: 61–9
  • Daley-Yates P, McBrien D. Cisplatin metabolites in plasma, a study of their pharmacokinetics and importance in the nephrotoxic and antitumour activity of cisplatin. Biochem Pharmacol. 1984; 33: 3063–70
  • Leppala J, Virtamo J, Fogelholm R. Controlled trial of alpha-tocopherol and beta-carotene supplements on stroke incidence and mortality in male smokers. Arterioscler Thromb Vasc Biol. 2000; 20: 230–5
  • Light J, Silverstein H. Transtympanic perfusion: indications and limitations. Curr Opin Otolaryngol Head Neck Surg. 2004; 12: 378–83
  • Halliwell B, Gutteridge J. Free Radicals in Biology and Medicine. Oxford University Press, Oxford 1993; 188–276
  • Fetoni A, Sergi B, Ferraresi A, Paludetti G, Troiani D. Protective effects of alpha-tocopherol and tiopronin against cisplatin-induced ototoxicity. Acta Otolaryngol. 2004; 124: 421–6

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