References
- Almurshedi AS, Radwan M, Omar S, et al. A novel pH-sensitive liposome to trigger delivery of afatinib to cancer cells: impact on lung cancer therapy. J Mol Liq. 2018;259:154–166.
- Jyoti K, Pandey RS, Kush P, et al. Inhalable bioresponsive chitosan microspheres of doxorubicin and soluble curcumin augmented drug delivery in lung cancer cells. Int J Biol Macromol. 2017;98:50–58.
- Xu J, Lu X, Zhu X, et al. Formulation and characterization of spray-dried powders containing vincristine-liposomes for pulmonary delivery and its pharmacokinetic evaluation from in vitro and in vivo. J Pharm Sci. 2019;108(10):3348–3358.
- Elmowafy E, Soliman ME. Losartan-chitosan/dextran sulfate microplex as a carrier to lung therapeutics: dry powder inhalation, aerodynamic profile and pulmonary tolerability. Int J Biol Macromol. 2019;136:220–229.
- He Y, Liang Y, Mak JCW, et al. Size effect of curcumin nanocrystals on dissolution, airway mucosa penetration, lung tissue distribution and absorption by pulmonary delivery. Colloids Surf B Biointerfaces. 2020;186:110703.
- Manish K, Nithya S, Rajnikanth PS, et al. Authors review on drug nanocrystals: a progress to targeted delivery. Curr Nanomed. 2020;10:1–23.
- Kumar M, Shanthi N, Mahato AK. Pharmaceutical drug nanocrystals: role in dermal delivery. Nanosci Nanotechnol Asia. 2019;9(3):300–310.
- Kumar M, Shanthi N, Mahato AK, et al. Preparation of luliconazole nanocrystals loaded hydrogel for improvement of dissolution and antifungal activity. Heliyon. 2019;5(5):e01688.
- Mohana Raghava Srivalli K, Mishra B. Drug nanocrystals: four basic prerequisites for formulation development and scale-up. Curr Drug Targets. 2015;16(2):136–147.
- Srivalli KMR, Mishra B. Drug nanocrystals: a way toward scale-up. Saudi Pharm J. 2016;24(4):386–404.
- Mangal S, Gao W, Li T, et al. Pulmonary delivery of nanoparticle chemotherapy for the treatment of lung cancers: challenges and opportunities. Acta Pharmacol Sin. 2017;38(6):782–797.
- Hu L, Kong D, Hu Q, et al. Evaluation of high-performance curcumin nanocrystals for pulmonary drug delivery both in vitro and in vivo. Nanoscale Res Lett. 2015;10(1):381.
- Zhang S, Wang J, Pan J. Baicalin-loaded PEGylated lipid nanoparticles: characterization, pharmacokinetics, and protective effects on acute myocardial ischemia in rats. Drug Deliv. 2016;23(9):3696–3703.
- Agrawal S, Dwivedi M, Ahmad H, et al. CD44 targeting hyaluronic acid coated lapatinib nanocrystals foster the efficacy against triple-negative breast cancer. Nanomedicine. 2018;14(2):327–337.
- Liu T, Han M, Tian F, et al. Budesonide nanocrystal-loaded hyaluronic acid microparticles for inhalation: in vitro and in vivo evaluation. Carbohydr Polym. 2018;181:1143–1152.
- Kurakula M, Ahmed TA. Co-delivery of atorvastatin nanocrystals in PLGA based in situ gel for anti-hyperlipidemic efficacy. Curr Drug Deliv. 2016;13(2):211–220.
- Wang H, Zhang G, Ma X, et al. Enhanced encapsulation and bioavailability of breviscapine in PLGA microparticles by nanocrystal and water-soluble polymer template techniques. Eur J Pharm Biopharm. 2017;115:177–185.
- Cipolla D, Wu H, Gonda I, et al. Aerosol performance and stability of liposomes containing ciprofloxacin nanocrystals. J Aerosol Med Pulm Drug Deliv. 2015;28(6):411–422.
- Abd Elwakil MM, Mabrouk MT, Helmy MW, et al. Inhalable lactoferrin–chondroitin nanocomposites for combined delivery of doxorubicin and ellagic acid to lung carcinoma. Nanomedicine. 2018;13(16):2015–2035.
- Elgohary MM, Helmy MW, Mortada SM, et al. Dual-targeted nano-in-nano albumin carriers enhance the efficacy of combined chemo/herbal therapy of lung cancer. Nanomedicine. 2018;13(17):2221–2224.
- Blank F, Rothen-Rutishauser BM, Schurch S, et al. An optimized in vitro model of the respiratory tract wall to study particle cell interactions. J Aerosol Med. 2006;19(3):392–405.
- Costabile G, Provenzano R, Azzalin A, et al. PEGylated mucus-penetrating nanocrystals for lung delivery of a new FtsZ inhibitor against Burkholderia cenocepacia infection. Nanomedicine: Nanotechnology, Biology and Medicine. 2020;23:102113.
- Hu X, Yang -F-F, Wei X-L, et al. Curcumin acetate nanocrystals for sustained pulmonary delivery: preparation, characterization and in vivo evaluation. J Biomed Nanotechnol. 2017;13(1):99–109.
- Noyes AA, Whitney WR. The rate of solution of solid substances in their own solutions. J Am Chem Soc. 1897;19(12):930–934.
- Paranjpe M, Müller-Goymann CC. Nanoparticle-mediated pulmonary drug delivery: a review. Int J Mol Sci. 2014;15(4):5852–5873.
- Ni R, Zhao J, Liu Q, et al. Nanocrystals embedded in chitosan-based respirable swellable microparticles as dry powder for sustained pulmonary drug delivery. Eur J Pharm Sci. 2017;99:137–146.
- Dandekar P, Venkataraman C, Mehra A. Pulmonary targeting of nanoparticle drug matrices. J Aerosol Med Pulm Drug Deliv. 2010;23(6):343–353.
- Dabbagh A, Abu Kasim NH, Yeong CH, et al. Critical parameters for particle-based pulmonary delivery of chemotherapeutics. J Aerosol Med Pulm Drug Deliv. 2018;31(3):139–154.
- Abdelaziz HM, Gaber M, Abd-Elwakil MM, et al. Inhalable particulate drug delivery systems for lung cancer therapy: nanoparticles, microparticles, nanocomposites and nanoaggregates. J Control Release. 2018;269:374–392.
- Chang T-L, Zhan H, Liang D, et al. Nanocrystal technology for drug formulation and delivery. Front Chem Sci Eng. 2015;9(1):1–14.
- Lu Y, Li Y, Wu W. Injected nanocrystals for targeted drug delivery. Acta Pharm Sin B. 2016;6(2):106–113.
- Jha A, Viswanadh MK, Burande AS, et al. DNA biodots based targeted theranostic nanomedicine for the imaging and treatment of non-small cell lung cancer. Int J Biol Macromol. 2020;150:413–425.
- Kumar M, Rajnikanth P. A mini-review on HER2 positive breast cancer and its metastasis: resistance and treatment strategies. Curr Nanomed. 2020;10(1):36–47.
- Noh J-K, Naeem M, Cao J, et al. Herceptin-functionalized pure paclitaxel nanocrystals for enhanced delivery to HER2-postive breast cancer cells. Int J Pharm. 2016;513(1–2):543–553.
- Choi J-S, Park J-S. Surface modification of docetaxel nanocrystals with HER2 antibody to enhance cell growth inhibition in breast cancer cells. Colloids Surf B Biointerfaces. 2017;159:139–150.
- Sohn JS, Yoon D-S, Sohn JY, et al. Development and evaluation of targeting ligands surface modified paclitaxel nanocrystals. Mater Sci Eng C. 2017;72:228–237.
- Lu Y, Wang Z-H, Li T, et al. Development and evaluation of transferrin-stabilized paclitaxel nanocrystal formulation. J Control Release. 2014;176:76–85.
- Zhan H, Jagtiani T, Liang JF. A new targeted delivery approach by functionalizing drug nanocrystals through polydopamine coating. Eur J Pharm Biopharm. 2017;114:221–229.
- Elgohary MM, Helmy MW, Abdelfattah E-ZA, et al. Targeting sialic acid residues on lung cancer cells by inhalable boronic acid-decorated albumin nanocomposites for combined chemo/herbal therapy. J Control Release. 2018;285:230–243.
- Huang Z-G, Lv F-M, Wang J, et al. RGD-modified PEGylated paclitaxel nanocrystals with enhanced stability and tumor-targeting capability. Int J Pharm. 2019;556:217–225.
- Jayasree A, Sasidharan S, Koyakutty M, et al. Mannosylated chitosan-zinc sulphide nanocrystals as fluorescent bioprobes for targeted cancer imaging. Carbohydr Polym. 2011;85(1):37–43.
- Park J, Sun B, Yeo Y. Albumin-coated nanocrystals for carrier-free delivery of paclitaxel. J Control Release. 2017;263:90–101.
- Han X, Su R, Huang X, et al. Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance. Asian J Pharm Sci. 2019;14(5):569–580.
- Wang H, Zhu W, Huang Y, et al. Facile encapsulation of hydroxycamptothecin nanocrystals into zein-based nanocomplexes for active targeting in drug delivery and cell imaging. Acta Biomater. 2017 Oct 01;61:88–100.
- Shafiu Kamba A, Ismail M, Tengku Ibrahim TA, et al. A pH-Sensitive, Biobased Calcium Carbonate Aragonite Nanocrystal as a Novel Anticancer Delivery System. BioMed Research International. 2013 Nov 14;2013:587451.
- Thuan D-VQH-V, Minh BL, Thinh PV, et al. Chemically modified hydroxyapatite nanocrystals by temperature-responsive Poly(N-isopropylacrylamide) via surface initiated radical polymerization. Asian J Chem. 2019 May 25;31(6):1221–1224.
- Li D, Tang J, Wei C, et al. Doxorubicin-conjugated mesoporous magnetic colloidal nanocrystal clusters stabilized by polysaccharide as a smart anticancer drug vehicle. Small. 2012 Sept 10;8(17):2690–2697.
- Li D, Tang J, Guo J, et al. Hollow-core magnetic colloidal nanocrystal clusters with ligand-exchanged surface modification as delivery vehicles for targeted and stimuli-responsive drug release. Chem Eur J. 2012 Dec 14;18(51):16517–16524.
- Meikle TG, Dyett BP, Strachan JB, et al. Preparation, characterization, and antimicrobial activity of cubosome encapsulated metal nanocrystals. ACS Appl Mater Interfaces. 2020 Feb 12;12(6):6944–6954.
- Kevadiya BD, Chen L, Zhang L, et al. Fenofibrate nanocrystal composite microparticles for intestine-specific oral drug delivery system. Pharmaceuticals. 2019;12(3):109.
- Xiao Y, Liu Q, Clulow AJ, et al. PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery. Colloids Surf B Biointerfaces. 2019 Oct 01;182:110362.
- Chowdhury EH. pH-sensitive nanocrystals of carbonate apatite-a powerful and versatile tool for efficient delivery of genetic materials to mammalian cells. Adv Biomater Sci Biomed Appl. 2013;265.
- Liang W, Kwok PCL, Chow MYT, et al. Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids. Eur J Pharm Biopharm. 2014 Jan 01;86(1):64–73.
- Wang Z, Li X, Wang D, et al. Concurrently suppressing multidrug resistance and metastasis of breast cancer by co-delivery of paclitaxel and honokiol with pH-sensitive polymeric micelles. Acta Biomater. 2017 Oct 15;62:144–156.
- Tang S, Meng Q, Sun H, et al. Dual pH-sensitive micelles with charge-switch for controlling cellular uptake and drug release to treat metastatic breast cancer. Biomaterials. 2017 Jan 01;114:44–53.
- Gonzalez-Fajardo L, Ndaya D, Kasi RM, et al. Influence of the method of preparation on the characteristics and performance of cholesterol-based polymeric nanoparticles for redox-triggered release of doxorubicin in tumor cells. Int J Pharm. 2019 Nov 25;571:118701.
- Chen X, Zhang Y, Tang C, et al. Co-delivery of paclitaxel and anti-survivin siRNA via redox-sensitive oligopeptide liposomes for the synergistic treatment of breast cancer and metastasis. Int J Pharm. 2017 Aug 30;529(1):102–115.
- Wu W, Li J, Liu W, et al. Temperature-sensitive, fluorescent Poly(N-Isopropyl-acrylamide)-grafted cellulose nanocrystals for drug release. BioResources. 2016 Jul 11;
- Qu Y, Chu BY, Peng JR, et al. A biodegradable thermo-responsive hybrid hydrogel: therapeutic applications in preventing the post-operative recurrence of breast cancer. Npg Asia Mater. 2015 Aug 01;7(8):e207–e207.
- Upadhyay D, Scalia S, Vogel R, et al. Magnetised thermo responsive lipid vehicles for targeted and controlled lung drug delivery. Pharm Res. 2012 Sept 01;29(9):2456–2467.
- Deka SR, Quarta A, Di Corato R, et al. Magnetic nanobeads decorated by thermo-responsive PNIPAM shell as medical platforms for the efficient delivery of doxorubicin to tumour cells [10.1039/C0NR00570C]. Nanoscale. 2011;3(2):619–629.
- Lin Z, Gao W, Hu H, et al. Novel thermo-sensitive hydrogel system with paclitaxel nanocrystals: high drug-loading, sustained drug release and extended local retention guaranteeing better efficacy and lower toxicity. J Control Release. 2014 Jan 28;174:161–170.
- Bielska D, Karewicz A, Kamiński K, et al. Self-organized thermo-responsive hydroxypropyl cellulose nanoparticles for curcumin delivery. Eur Polym J. 2013 Sept 01;49(9):2485–2494.
- Chen K-J, Liang H-F, Chen H-L, et al. A thermoresponsive bubble-generating liposomal system for triggering localized extracellular drug delivery. ACS Nano. 2013 Jan 22;7(1):438–446.
- Park JW, Bae KH, Kim C, et al. Clustered magnetite nanocrystals cross-linked with PEI for efficient siRNA delivery. Biomacromolecules. 2011 Feb 14;12(2):457–465.
- Tagami T, Ando Y, Ozeki T. Fabrication of liposomal doxorubicin exhibiting ultrasensitivity against phospholipase A2 for efficient pulmonary drug delivery to lung cancers. Int J Pharm. 2017 Jan 30;517(1):35–41.
- Qu Y, Chu B, Wei X, et al. Redox/pH dual-stimuli responsive camptothecin prodrug nanogels for “on-demand” drug delivery. J Control Release. 2019 Feb 28;296:93–106.
- Luo L, Xu F, Peng H, et al. Stimuli-responsive polymeric prodrug-based nanomedicine delivering nifuroxazide and doxorubicin against primary breast cancer and pulmonary metastasis. J Control Release. 2020 Feb 01;318:124–135.
- Noh MS, Lee S, Kang H, et al. Target-specific near-IR induced drug release and photothermal therapy with accumulated Au/Ag hollow nanoshells on pulmonary cancer cell membranes. Biomaterials. 2015 Mar 01;45:81–92.
- Wang F, Huang Q, Wang Y, et al. NIR-light and GSH activated cytosolic p65-shRNA delivery for precise treatment of metastatic cancer. J Control Release. 2018 Oct 28;288:126–135.
- De Backer L, Braeckmans K, Stuart MCA, et al. Bio-inspired pulmonary surfactant-modified nanogels: a promising siRNA delivery system. J Control Release. 2015 May 28;206:177–186.
- de Oliveira Silva J, Fernandes RS, Ramos Oda CM, et al. Folate-coated, long-circulating and pH-sensitive liposomes enhance doxorubicin antitumor effect in a breast cancer animal model. Biomed Pharmacother. 2019 Oct 01;118:109323.
- Tseng C-L, Wu SY-H, Wang W-H, et al. Targeting efficiency and biodistribution of biotinylated-EGF-conjugated gelatin nanoparticles administered via aerosol delivery in nude mice with lung cancer. Biomaterials. 2008 Jul 01;29(20):3014–3022.
- Amararathna M, Goralski K, Hoskin DW, et al. Pulmonary nano-drug delivery systems for lung cancer: current knowledge and prospects. J Lung Health Dis. 2019;3(2):11–28.
- Khatib I, Tang P, Ruan J, et al. Formation of ciprofloxacin nanocrystals within liposomes by spray drying for controlled release via inhalation. Int J Pharm. 2020;578:119045.
- Wang Z, Gupta SK, Meenach SA. Development and physicochemical characterization of acetalated dextran aerosol particle systems for deep lung delivery. Int J Pharm. 2017;525(1):264–274.
- Marianecci C, Paolino D, Celia C, et al. Non-ionic surfactant vesicles in pulmonary glucocorticoid delivery: characterization and interaction with human lung fibroblasts. J Control Release. 2010;147(1):127–135.
- Yang W, Chow KT, Lang B, et al. In vitro characterization and pharmacokinetics in mice following pulmonary delivery of itraconazole as cyclodextrin solubilized solution. Eur J Pharm Sci. 2010;39(5):336–347.