Osseointegrated prostheses for the rehabilitation of amputees (OPRA): results and clinical perspective

References

• Ziegler-Graham K, MacKenzie EJ, Ephraim PL, et al. Estimating the prevalence of limb loss in the United States: 2005 to 2050. Arch Phys Med Rehabil. 2008;89(3):422–429.
   PubMed Web of Science ®Google Scholar
• Chen L, Magliano DJ, Zimmet PZ. The worldwide epidemiology of type 2 diabetes mellitus–present and future perspectives. Nat Rev Endocrinol. 2011;8(4):228–236.
   PubMed Web of Science ®Google Scholar
• Kirk NT. The development of amputation. Bull Med Libr Assoc. 1944;32(2):132–163.
   Google Scholar
• Sachs M, Bojunga J, Encke A. Historical evolution of limb amputation. World J Surg. 1999;23(10):1088–1093.
   PubMed Web of Science ®Google Scholar
• Reznick JS. Beyond war and military medicine: social factors in the development of prosthetics. Arch phys Med Rehab. 2008;89(1):188–193.
   PubMed Web of Science ®Google Scholar
• American Academy of Orthopaedic Surgeons. Atlas of limb prosthetics: Surgical, Prosthetic, and Rehabilitation Principles. Mosby Year Book. 1992;2:12–31.
   Google Scholar
• Leijendekkers RA, van Hinte G, Frölke JP, et al. Comparison of bone-anchored prostheses and socket prostheses for patients with a lower extremity amputation: a systematic review. Disabil Rehabil. 2017;39(11):1045–1058.
   PubMed Web of Science ®Google Scholar
• John J Zion market research. 2019. [cited 2019 Nov]. Available from: globalnewswire.com.
   Google Scholar
• Thesleff A, Brånemark R, Håkansson B, et al. Biomechanical characterisation of bone-anchored implant systems for amputation limb prostheses: a systematic review. Ann Biomed Eng. 2018;46(3):377–391.
   PubMed Web of Science ®Google Scholar
• Aschoff HH, Kennon RE, Keggi JM, et al. Transcutaneous, distal femoral, intramedullary attachment for above-the-knee prostheses: an endo-exo device. J Bone Joint Surg Am Volume. 2010;92(Suppl 2):180–186.
   PubMedGoogle Scholar
• Frölke JPM, Leijendekkers RA, van de Meent H. Osseointegrated prosthesis for patients with an amputation: multidisciplinary team approach in the Netherlands. Unfallchirurg. 2017;120(4):293–299.
   PubMed Web of Science ®Google Scholar
• Guirao L, Samitier B, Tibau R, et al. Distance and speed of walking in individuals with trans-femoral amputation fitted with a distal weight-bearing implant. Orthop Traumatol Surg Res. 2018;104(6):929–933.
   PubMed Web of Science ®Google Scholar
• Zaid MB, OʼDonnell RJ, Potter BK, et al. Orthopaedic osseointegration: state of the art. J Am Acad Orthop Surg. 2019;27(22):e977-985. Publish Ahead of Print.
   PubMedGoogle Scholar
• Prochor P, Sajewicz E. The influence of geometry of implants for direct skeletal attachment of limb prosthesis on rehabilitation program and stress-shielding intensity. Biomed Res Int. 2019;2019(1): 6067952–17.
   PubMedGoogle Scholar
• Yerby S, Scott CC, Evans NJ, et al. Effect of cutting flute design on cortical bone screw insertion torque and pullout strength. J Orthop Trauma. 2001;15(3):216–221.
   PubMed Web of Science ®Google Scholar
• Brånemark R, Emanuelsson L, Palmquist A, et al. Bone response to laser-induced micro- and nano-size titanium surface features. Nanomedicine. 2011;7(2):220–227.
   PubMed Web of Science ®Google Scholar
• Li Y, Brånemark R. Osseointegrated prostheses for rehabilitation following amputation: the pioneering Swedish model. Unfallchirurg. 2017;120(4):285–292.
   PubMed Web of Science ®Google Scholar
• Muderis AM, Lu W, Tetsworth K, et al. Single-stage osseointegrated reconstruction and rehabilitation of lower limb amputees: the osseointegration group of australia accelerated protocol-2 (OGAAP-2) for a prospective cohort study. BMJ Open. 2017;7(3):e013508.
   PubMed Web of Science ®Google Scholar
• Nebergall A, Bragdon C, Antonellis A, et al. Stable fixation of an osseointegated implant system for above-the-knee amputees: titel RSA and radiographic evaluation of migration and bone remodeling in 55 cases. Acta Orthop. 2012;83(2):121–128.
   PubMed Web of Science ®Google Scholar
• Pendegrass CJ, Goodship AE, Price JS, et al. Nature’s answer to breaching the skin barrier: an innovative development for amputees. J Anat. 2006;209(1):59–67.
   PubMed Web of Science ®Google Scholar
• Hagberg K, Brånemark R. One hundred patients treated with osseointegrated transfemoral amputation prostheses–rehabilitation perspective. J Rehabil Res Dev. 2009;46(3):331–344.
   PubMed Web of Science ®Google Scholar
• Haggstrom EE, Hansson E, Hagberg K. Comparison of prosthetic costs and service between osseointegrated and conventional suspended transfemoral prostheses. Prosthet Orthot Int. 2013;37(2):152–160.
   PubMed Web of Science ®Google Scholar
• Frossard LA, Merlo G, Burkett B, et al. Cost-effectiveness of bone-anchored prostheses using osseointegrated fixation: myth or reality? Prosthet Orthot Int. 2018;42(3):318–327.
   PubMed Web of Science ®Google Scholar
• Hansson E, Hagberg K, Cawson M, et al. Patients with unilateral transfemoral amputation treated with a percutaneous osseointegrated prosthesis: a cost-effectiveness analysis. JBJS Br. 2018;100-B(4):527–534.
   Google Scholar
• McFarland LV, Hubbard Winkler SL, Heinemann AW, et al. Unilateral upper-limb loss: satisfaction and prosthetic-device use in veterans and servicemembers from Vietnam and OIF/OEF conflicts. J Rehabil Res Dev. 2010;47(4):299–316.
   PubMedGoogle Scholar
• Hagberg K, Brånemark R, Gunterberg B, et al. Osseointegrated trans-femoral amputation prostheses: prospective results of general and condition-specific quality of life in 18 patients at 2-year follow-up. Prosthet Orthot Int. 2008;32(1):29–41.
   PubMed Web of Science ®Google Scholar
• Hagberg K, Brånemark R, Hägg O. Questionnaire for persons with a transfemoral amputation (Q-TFA): initial validity and reliability of a new outcome measure. J Rehabil Res Dev. 2004;41(5):695–706.
   PubMed Web of Science ®Google Scholar
• Hagberg K, Hansson E, Brånemark R. Outcome of percutaneous osseointegrated prostheses for patients with unilateral transfemoral amputation at two-year follow-up. Arch Phys Med Rehabil. 2014;95(11):2120–2127.
   PubMed Web of Science ®Google Scholar
• Brånemark R, Berlin O, Hagberg K, et al. A novel osseointegrated percutaneous prosthetic system for the treatment of patients with transfemoral amputation: A prospective study of 51 patients. JBJS Br. 2014;96-B(1):106–113.
   Google Scholar
• Matthews DJ, Arastu M, Uden M, et al. UK trial of the osseointegrated prosthesis for the rehabilitation for amputees: 1995–2018. Prosthet Orthot Int. 2019;43(1):112–122.
   PubMed Web of Science ®Google Scholar
• Hagberg K. Bone-anchored prostheses in patients with traumatic bilateral transfemoral amputations: rehabilitation description and outcome in 12 cases treated with the OPRA implant system. Disabil Rehabil Assist Technol. 2019;14(4):346–353.
   PubMed Web of Science ®Google Scholar
• van de Meent H, Hopman MT, Frölke JP. Walking ability and quality of life in subjects with transfemoral amputation: a comparison of osseointegration with socket prostheses. Arch Phys Med Rehabil. 2013;94(11):2174–2178.
   PubMed Web of Science ®Google Scholar
• Tsikandylakis G, Berlin Ö, Brånemark R. Implant survival, adverse events, and bone remodeling of osseointegrated percutaneous implants for transhumeral amputees. Clin Orthop Relat Res. 2014;472(10):2947–2956.
   PubMed Web of Science ®Google Scholar
• Jönsson S, Caine-Winterberger K, Brånemark R. Osseointegration amputation prostheses on the upper limbs: methods, prosthetics and rehabilitation. Prosthet Orthot Int. 2011;35(2):190–200.
   PubMed Web of Science ®Google Scholar
• Brånemark RP, Hagberg K, Kulbacka-Ortiz K, et al. Osseointegrated percutaneous prosthetic system for the treatment of patients with transfemoral amputation: a prospective five-year follow-up of patient-reported outcomes and complications. J Am Acad Orthop Surg. 2019;27(16):e743–e751.
   PubMedGoogle Scholar
• Muderis AM, Khemka A, Lord SJ, et al. Safety of osseointegrated implants for transfemoral amputees: a two-center prospective cohort study. J Bone Joint Surg Am Volume. 2016;98(11):900–909.
   PubMed Web of Science ®Google Scholar
• Tillander J, Hagberg K, Berlin Ö, et al. Osteomyelitis risk in patients with transfemoral amputations treated with osseointegration prostheses. Clin Orthop Relat Res. 2017;475(12):3100–3108.
   PubMed Web of Science ®Google Scholar
• Juhnke D-L, Beck JP, Jeyapalina S, et al. Fifteen years of experience with integral-leg-prosthesis: cohort study of artificial limb attachment system. J Rehabil Res Dev. 2015;52(4):407–420.
   PubMedGoogle Scholar
• Kunutsor SK, Gillatt D, Blom AW. Systematic review of the safety and efficacy of osseointegration prosthesis after limb amputation. Br J Surg. 2018;105(13):1731–1741.
   PubMed Web of Science ®Google Scholar
• Health Quality Ontario. Osseointegrated prosthetic implants for people with lower-limb amputation: a health technology assessment. hqontario.ca. 2019. p. 1–124
   Google Scholar
• Ortiz-Catalan M, Håkansson B, Brånemark R. An osseointegrated human-machine gateway for long-term sensory feedback and motor control of artificial limbs. Sci Transl Med. 2014;6(257):257re6–257re6.
   PubMed Web of Science ®Google Scholar
• Haket LM, Frölke JPM, Verdonschot N, et al. Periprosthetic cortical bone remodeling in patients with an osseointegrated leg prosthesis. J Orthop Res. 2017;35(6):1237–1241.
   PubMed Web of Science ®Google Scholar
• Connaughton A, Childs A, Dylewski S, et al. Biofilm disrupting technology for orthopedic implants: what’s on the horizon? Front Med (Lausanne). 2014;1(9):22.
   PubMedGoogle Scholar
• Ashrafi M, Novak-Frazer L, Morris J, et al. Electrical stimulation disrupts biofilms in a human wound model and reveals the potential for monitoring treatment response with volatile biomarkers. Wound Repair Regen. 2019;27(1):5–18.
   PubMed Web of Science ®Google Scholar
• Mastinu E, Doguet P, Botquin Y, et al. Embedded system for prosthetic control using implanted neuromuscular interfaces accessed via an osseointegrated implant. IEEE Trans Biomed Circuits Syst. 2017;11(4):867–877.
   PubMed Web of Science ®Google Scholar
• Mastinu E, Clemente F, Sassu P, et al. Grip control and motor coordination with implanted and surface electrodes while grasping with an osseointegrated prosthetic hand. J Neuroeng Rehabil. 2019;16(1):49.
   PubMedGoogle Scholar
• Pasquina PF, Evangelista M, Carvalho AJ, et al. First-in-man demonstration of a fully implanted myoelectric sensors system to control an advanced electromechanical prosthetic hand. J Neurosci Methods. 2015;244:85–93.
   PubMed Web of Science ®Google Scholar