343
Views
15
CrossRef citations to date
0
Altmetric
Original Article

Quantitative histochemistry for macrophage biodistribution on mice liver and spleen after the administration of a pharmacological-relevant dose of polyacrylic acid-coated iron oxide nanoparticles

ORCID Icon, ORCID Icon, ORCID Icon, , , , ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 256-266 | Received 05 May 2016, Accepted 31 Jan 2017, Published online: 23 Feb 2017

References

  • Ahamed M, Alhadlaq HA, Alam J, Khan MA, Ali D, Alarafi S. 2013. Iron oxide nanoparticle-induced oxidative stress and genotoxicity in human skin epithelial and lung epithelial cell lines. Curr Pharm Des 19:6681–90.
  • Altamura S, Kessler R, Gröne HJ, Gretz N, Hentze M, Galy B, Muckenthaler M. 2014. Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload. Cell Metab 20:359–67.
  • Arami H, Khandhar A, Liggitt D, Krishnan KM. 2015. In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles. Chem Soc Rev 44:8576–607.
  • Babic M, Horak D, Trchova M, Jendelova P, Glogarova K, Lesny P, et al. 2008. Poly(L-lysine)-modified iron oxide nanoparticles for stem cell labeling. Bioconjug Chem 19:740–50.
  • Baratta JL, Ngo A, Lopez B, Kasabwalla N, Longmuir KJ, Robertson RT. 2009. Cellular organization of normal mouse liver: a histological, quantitative immunocytochemical, and fine structural analysis. Histochem Cell Biol 131:713–26.
  • Batts KP. 2007. Iron overload syndromes and the liver. Mod Pathol 20:S31–9.
  • Beck BD, Seeley M, Calabrese EJ. 2014. The use of toxicology in the regulatory process. In: Hayes AW, Kruger CL, eds. Haye's Principles and Methods of Toxicology. 6th ed. Boca Raton, FL: CRC Press, 35–87.
  • Beckmann N, Cannet C, Fringeli-Tanner M, Baumann D, Pally C, Bruns C, et al. 2003. Macrophage labeling by SPIO as an early marker of allograft chronic rejection in a rat model of kidney transplantation. Magn Reson Med 49:459–67.
  • Bourrinet P, Bengele HH, Bonnemain B, Dencausse A, Idee JM, Jacobs PM, Lewis JM. 2006. Preclinical safety and pharmacokinetic profile of ferumoxtran-10, an ultrasmall superparamagnetic iron oxide magnetic resonance contrast agent. Invest Radiol 41:313–24.
  • Bouwens L, Baekeland M, De Zanger R, Wisse E. 1986. Quantitation, tissue distribution and proliferation kinetics of Kupffer cells in normal rat liver. Hepatology 6:718–22.
  • Brissot P, Wright TL, Ma WL, Weisiger RA. 1985. Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states. J Clin Invest 76:1463–70.
  • Brunet S, Thibault L, Delvin E, Yotov W, Bendayan M, Levy E. 1999. Dietary iron overload and induced lipid peroxidation are associated with impaired plasma lipid transport and hepatic sterol metabolism in rats. Hepatology 29:1809–17.
  • Burugapalli K, Koul V, Dinda AK. 2004. Effect of composition of interpenetrating polymer network hydrogels based on poly (acrylic acid) and gelatin on tissue response: a quantitative in vivo study. J Biomed Mater Res A 68:210–8.
  • Cao B, Qiu P, Mao C. 2013. Mesoporous iron oxide nanoparticles prepared by polyacrylic acid etching and their application in gene delivery to mesenchymal stem cells. Microsc Res Tech 76:936–41.
  • Cardoso EMP, Hagen K, De Sousa M, Hultcrantz R. 2001. Hepatic damage in C282Y homozygotes relates to low numbers of CD8+ cells in the liver lobuli. Eur J Clin Invest 31:45–53.
  • Clichici S, Biris AR, Catoi C, Filip A, Tabaran F. 2014. Short-term splenic impact of single-strand DNA functionalized multi-walled carbon nanotubes intraperitoneally injected in rats. J Appl Toxicol 34:332–44.
  • Couto D, Freitas M, Carvalho F, Fernandes E. 2015a. Iron oxide nanoparticles: an insight into their biomedical applications. Curr Med Chem 22:1808–28.
  • Couto D, Freitas M, Costa VM, Chisté RC, Almeida A, Lopez-Quintela MA, et al. 2016. Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity. J Appl Toxicol. 36:1321–31.
  • Couto D, Freitas M, Vilas-Boas V, Dias I, Porto G, Lopez-Quintela MA, et al. 2014. Interaction of polyacrylic acid coated and non-coated iron oxide nanoparticles with human neutrophils. Toxicol Lett 225:57–65.
  • Couto D, Sousa R, Andrade L, Leander M, Lopez-Quintela MA, Rivas J, et al. 2015b. Polyacrylic acid coated and non-coated iron oxide nanoparticles are not genotoxic to human T lymphocytes. Toxicol Lett 234:67–73.
  • Davies LC, Jenkins SJ, Allen JE, Taylor PR. 2013. Tissue-resident macrophages. Nat Immunol 14:986–95.
  • den Haan JM, Kraal G. 2012. Innate immune functions of macrophage subpopulations in the spleen. J Innate Immun 4:437–45.
  • Duguet E, Vasseur S, Mornet S, Devoisselle JM. 2006. Magnetic nanoparticles and their applications in medicine. Nanomedicine (Lond) 1:157–68.
  • Egger C, Cannet C, Gerard C, Debon C, Stohler N, Dunbar A, et al. 2015. Adriamycin-induced nephropathy in rats: functional and cellular effects characterized by MRI. J Magn Reson Imaging 41:829–40.
  • Hohnholt MC, Geppert M, Luther EM, Petters C, Bulcke F, Dringen R. 2012. Handling of iron oxide and silver nanoparticles by astrocytes. Neurochem Res 38:227–39.
  • Hosemann W, Teutsch HF, Sasse D. 1979. Identification of G6PDH-active sinusoidal cells as Kupffer cells in the rat liver. Cell Tissue Res 196:237–47.
  • Iancu TC, Deugnier Y, Halliday JW, Powell LW, Brissot P. 1997. Ultrastructural sequences during liver iron overload in genetic hemochromatosis. J Hepatol 27:628–38.
  • Issa B, Obaidat IM, Albiss BA, Haik Y. 2013. Magnetic nanoparticles: surface effects and properties related to biomedicine applications. Int J Mol Sci 14:21266–305.
  • Iversen NK, Frische S, Thomsen K, Laustsen C, Pedersen M, Hansen PBL, et al. 2013. Superparamagnetic iron oxide polyacrylic acid coated γ-Fe2O3 nanoparticles do not affect kidney function but cause acute effect on the cardiovascular function in healthy mice. Toxicol Appl Pharmacol 266:276–88.
  • Kaneda K, Wake K. 1983. Distribution and morphological characteristics of the pit cells in the liver of the rat. Cell Tissue Res 233:485–505.
  • Kiernan JA. 1999. Histological and histochemical methods: theory and practice. Shock 12:479.
  • Kim JE, Shin JY, Cho MH. 2012. Magnetic nanoparticles: an update of application for drug delivery and possible toxic effects. Arch Toxicol 86:685–700.
  • Kolios G, Valatas V, Kouroumalis E. 2006. Role of Kupffer cells in the pathogenesis of liver disease. World J Gastroenterol 12:7413–20.
  • Kolosnjaj-Tabi J, Javed Y, Lartigue L, Volatron J, Elgrabli D, Marangon I, et al. 2015. The one year fate of iron oxide coated gold nanoparticles in mice. ACS Nano 9:7925–39.
  • Kooi ME, Cappendijk VC, Cleutjens KBJM, Kessels AGH, Kitslaar PJEHM, Borgers M, et al. 2003. Accumulation of ultrasmall superparamagnetic particles of iron oxide in human atherosclerotic plaques can be detected by in vivo magnetic resonance imaging. Circulation 107:2453–8.
  • Kubinova S, Sykova E. 2010. Nanotechnologies in regenerative medicine. Minim Invasive Ther Allied Technol 19:144–56.
  • Lartigue L, Alloyeau D, Kolosnjaj-Tabi J, Javed Y, Guardia P, Riedinger A, et al. 2013. Biodegradation of iron oxide nanocubes: high-resolution in situ monitoring. ACS Nano 7:3939–52.
  • Levy M, Luciani N, Alloyeau D, Elgrabli D, Deveaux V, Pechoux C, et al. 2011. Long term in vivo biotransformation of iron oxide nanoparticles. Biomaterials 32:3988–99.
  • Ma P, Luo Q, Chen J, Gan Y, Du J, Ding S, et al. 2012. Intraperitoneal injection of magnetic Fe(3)O(4)-nanoparticle induces hepatic and renal tissue injury via oxidative stress in mice. Int J Nanomedicine 7:4809–18.
  • Mebius RE, Kraal G. 2005. Structure and function of the spleen. Nat Rev Immunol 5:606–16.
  • Meena R, Paulraj R. 2012. Oxidative stress mediated cytotoxicity of TiO2 nano anatase in liver and kidney of Wistar rat. Toxicol Environ Chem 94:146–63.
  • Moyo VM, Makunike R, Gangaidzo IT, Gordeuk VR, Mclaren CE, Khumalo H, et al. 1998. African iron overload and hepatocellular carcinoma (HA-7-0-080). Eur J Haematol 60:28–34.
  • Perry JL, Reuter KG, Kai MP, Herlihy KP, Jones SW, Luft JC, et al. 2012. PEGylated PRINT nanoparticles: the impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics. Nano Lett 12:5304–10.
  • Pineiro-Redondo Y, Banobre-Lopez M, Pardinas-Blanco I, Goya G, Lopez-Quintela MA, Rivas J. 2011. The influence of colloidal parameters on the specific power absorption of PAA-coated magnetite nanoparticles. Nanoscale Res Lett 6:383.
  • Ponka P. 1999. Cellular iron metabolism. Kidney Int 69:S2–S11.
  • Qiu D, Zaharchuk G, Christen T, Ni WW, Moseley ME. 2012. Contrast-enhanced functional blood volume imaging (CE-fBVI): enhanced sensitivity for brain activation in humans using the ultrasmall superparamagnetic iron oxide agent ferumoxytol. NeuroImage 62:1726–31.
  • Ramos E, Ruchala P, Goodnough JB, Kautz L, Preza GC, Nemeth E, Ganz T. 2012. Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood 120:3829–36.
  • Rehg JE, Bush D, Ward JM. 2012. The utility of immunohistochemistry for the identification of hematopoietic and lymphoid cells in normal tissues and interpretation of proliferative and inflammatory lesions of mice and rats. Toxicol Pathol 40:345–74.
  • Roohi F, Lohrke J, Ide A, Schutz G, Dassler K. 2012. Studying the effect of particle size and coating type on the blood kinetics of superparamagnetic iron oxide nanoparticles. Int J Nanomedicine 7:4447–58.
  • Ruiz A, Hernandez Y, Cabal C, Gonzalez E, Veintemillas-Verdaguer S, Martinez E, Morales MP. 2013. Biodistribution and pharmacokinetics of uniform magnetite nanoparticles chemically modified with polyethylene glycol. Nanoscale 5:11400–8.
  • Shubayev VI, Pisanic Ii TR, Jin S. 2009. Magnetic nanoparticles for theragnostics. Adv Drug Deliv Rev 61:467–77.
  • Sleyster EC, Knook DL. 1982. Relation between localization and function of rat liver Kupffer cells. Lab Invest 47:484–90.
  • Soenen SJ, Parak WJ, Rejman J, Manshian B. 2015. (Intra)Cellular stability of inorganic nanoparticles: effects on cytotoxicity, particle functionality, and biomedical applications. Chem Rev 115:2109–35.
  • Sun SL, Lo YL, Chen HY, Wang LF. 2012. Hybrid polyethylenimine and polyacrylic acid-bound iron oxide as a magnetoplex for gene delivery. Langmuir 28:3542–52.
  • Teixeira L, Moreira J, Melo J, Bezerra F, Marques RM, Ferreirinha P, et al. 2015. Immune response in the adipose tissue of lean mice infected with the protozoan parasite Neospora caninum. Immunology 145:242–57.
  • Tenenbein M. 2001. Hepatotoxicity in acute iron poisoning. J Toxicol Clin Toxicol 39:721–6.
  • Wahajuddin, Arora S. 2012. Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers. Int J Nanomedicine 7:3445–71.
  • Xiong S, She H, Zhang AS, Wang J, Mkrtchyan H, Dynnyk A, et al. 2008. Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis. Am J Physiol-Gastr L 295:G512–21.
  • Zhou XY, Tomatsu S, Fleming RE, Parkkila S, Waheed A, Jiang J, et al. 1998. HFE gene knockout produces mouse model of hereditary hemochromatosis. Proc Natl Acad Sci USA 95:2492–7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.