124
Views
11
CrossRef citations to date
0
Altmetric
Articles

Efficient anti-tumor nano-lipoplexes with unsaturated or saturated lipid induce differential genotoxic effects in mice

, , , , , , , , & ORCID Icon show all
Pages 1161-1175 | Received 10 Mar 2019, Accepted 09 Jul 2019, Published online: 25 Jul 2019

References

  • Ahmad, A., S. K. Mondal, D. Mukhopadhyay, R. Banerjee, and K. M. Alkharfy. 2016. “Development of Liposomal Formulation for Delivering Anticancer Drug to Breast Cancer Stem-Cell-like Cells and Its Pharmacokinetics in an Animal Model.” Molecular Pharmaceutics 13(3): 1081–1088. doi:10.1021/acs.molpharmaceut.5b00900.
  • Alexander, J. F., D. Aguirre-Villarreal, and B. Godin. 2017. “Liposomal Encapsulation Masks Genotoxicity of a Chemotherapeutic Agent in Regulatory Toxicology Assessments.” Nanomedicine: Nanotechnology, Biology, and Medicine 13(3): 829–833. doi:10.1016/j.nano.2016.12.016.
  • Anselmo, A. C., and S. Mitragotri. 2016. “Nanoparticles in the Clinic.” Bioengineering & Translational Medicine 1(1): 10–29. doi:10.1002/btm2.10003.
  • AshaRani, P. V., G. Low Kah Mun, M. P. Hande, and S. Valiyaveettil. 2009. “Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells.” ACS Nano 3(2): 279–290. doi:10.1021/nn800596w.
  • Bulbake, U., S. Doppalapudi, N. Kommineni, and W. Khan. 2017. “Liposomal Formulations in Clinical Use: An Updated Review.” Pharmaceutics 9(4): 12. doi:10.3390/pharmaceutics9020012.
  • Chang, H., M. Cheng, and M. Yeh. 2012. “Clinically-Proven Liposome-Based Drug Delivery: Formulation Characterization and Therapeutic Efficacy.” Open Access Scientific Reports 1: 195. doi:10.4172/scientificreports.
  • Conde, J., M. Larguinho, A. Cordeiro, L. R. Raposo, P. M. Costa, S. Santos, M. S. Diniz, A. R. Fernandes, and P. V. Baptista. 2014. “Gold-Nanobeacons for Gene Therapy: Evaluation of Genotoxicity, Cell Toxicity and Proteome Profiling Analysis.” Nanotoxicology 8(5): 521–532. doi:10.3109/17435390.2013.802821.
  • Deshpande, P. P., S. Biswas, and V. P. Torchilin. 2013. “Current Trends in the Use of Liposomes for Tumor Targeting.” Nanomedicine 8(9): 1509–1528. doi:10.2217/nnm.13.118.
  • Eichhorn, M. E., S. Becker, S. Strieth, A. Werner, B. Sauer, M. Teifel, H. Ruhstorfer, U. Michaelis, J. Griebel, and G. Brix. 2006. “Paclitaxel Encapsulated in Cationic Lipid Complexes (MBT-0206) Impairs Functional Tumor Vascular Properties as Detected by Dynamic Contrast Enhanced Magnetic Resonance Imaging.” Cancer Biology & Therapy 5(1): 89–96. doi:10.4161/cbt.5.1.2346.
  • Eichhorn, M. E., I. Ischenko, S. Luedemann, S. Strieth, A. Papyan, A. Werner, H. Bohnenkamp, E. Guenzi, G. Preissler, and U. Michaelis 2010. “Vascular Targeting by EndoTAG™‐1 Enhances Therapeutic Efficacy of Conventional Chemotherapy in Lung and Pancreatic Cancer.” International Journal of Cancer 126(5): 1235–1245. doi:10.1002/ijc.24846.
  • Hua, J., N. Gross, B. Schulze, U. Michaelis, H. Bohnenkamp, E. Guenzi, L. L. Hansen, G. Martin, and H. T. Agostini. 2012. “In Vivo Imaging of Choroidal Angiogenesis Using Fluorescence-Labeled Cationic Liposomes.” Molecular Vision 18: 1045.
  • Immordino, M. L., F. Dosio, and L. Cattel. 2006. “Stealth Liposomes: Review of the Basic Science, Rationale, and Clinical Applications, Existing and Potential.” International Journal of Nanomedicine 1(3): 297.
  • Knudsen, K. B., H. Northeved, P. Kumar Ek, A. Permin, T. Gjetting, T. L. Andresen, S. Larsen., et al. 2015. “In Vivo Toxicity of Cationic Micelles and Liposomes.” Nanomedicine: Nanotechnology, Biology and Medicine 11(2): 467–477. doi:10.1016/j.nano.2014.08.004.
  • Koynova, R., L. Wang, and R. C. MacDonald. 2006. “An Intracellular Lamellar–Nonlamellar Phase Transition Rationalizes the Superior Performance of Some Cationic Lipid Transfection Agents.” Proceedings of the National Academy of Sciences of the United States of America 103(39): 14373–14378. doi:10.1073/pnas.0603085103.
  • Lee, S. M., J. S. Kim, Y. K. Oh, Y. B. Lee, and H. Sah. 2005. “Biodistribution and Genotoxicity of Transferrin-Conjugated Liposomes/DNA Complexes in Mice.” Macromolecular Research 13(3): 218–222. doi:10.1007/BF03219055.
  • Marepally, S., V. Chandrashekhar, R. C. Reddy, R. Prabhakar, S. Bojja, and A. Chaudhuri. 2011. “The Influence of the Structural Orientation of Amide Linkers on the Serum Compatibility and Lung Transfection Properties of Cationic Amphiphiles.” Biomaterials 32 (22): 5231–5240. doi:10.1016/j.biomaterials.2011.03.059
  • Meka, R. R., S. Godeshala, S. Marepally, K. Thorat, H. K. Reddy Rachamalla, A. Dhayani, A. Hiwale, R. Banerjee, A. Chaudhuri, and P. K. Vemula. 2016. “Asymmetric Cationic Lipid Based Non-Viral Vectors for an Efficient Nucleic Acid Delivery.” RSC Advances 6(81): 77841–77848. doi:10.1039/C6RA07256A.
  • Mondal, S. K., S. Jinka, K. Pal, S. Nelli, S. K. Dutta, E. Wang, A. Ahmad, K. M. AlKharfy, D. Mukhopadhyay, and R. Banerjee. 2016. “Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.” Molecular Pharmaceutics 13(7): 2507–2523. doi:10.1021/acs.molpharmaceut.6b00230.
  • Pattni, B. S., V. V. Chupin, and V. P. Torchilin. 2015. “New Developments in Liposomal Drug Delivery.” Chemical Reviews 115(19): 10938–10966. doi:10.1021/acs.chemrev.5b00046.
  • Pore, S. K., A. Choudhary, B. Rathore, A. Ganguly, P. Sujitha, C. G. Kumar, S. B. Agawane, et al. 2013. “Hsp90-Targeted miRNA-Liposomal Formulation for Systemic Antitumor Effect.” Biomaterials 34(28): 6804–6817. doi:10.1016/j.biomaterials.2013.05.054.
  • Rosenblum, D., N. Joshi, W. Tao, J. M. Karp, and D. Peer. 2018. “Progress and Challenges towards Targeted Delivery of Cancer Therapeutics.” Nature Communications 9(1): 1410. doi:10.1038/s41467-018-03705-y.
  • Sinha, S., S. Roy, B. S. Reddy, K. Pal, G. Sudhakar, S. Iyer, S. Dutta, E. Wang, P. K. Vohra, K. R. Roy, et al. 2011. “A Lipid-Modified Estrogen Derivative That Treats Breast Cancer Independent of Estrogen Receptor Expression through Simultaneous Induction of Autophagy and Apoptosis.” Molecular Cancer Research 9(3): 364–374. doi:10.1158/1541-7786.MCR-10-0526.
  • Vasievich, E. A., W. Chen, and L. Huang. 2011. “Enantiospecific Adjuvant Activity of Cationic Lipid DOTAP in Cancer Vaccine.” Cancer Immunology, Immunotherapy 60(5): 629–638. doi:10.1007/s00262-011-0970-1.
  • Xie, H., M. M. Mason, and J. P. Wise, Sr. 2011. “Genotoxicity of Metal Nanoparticles.” Reviews on Environmental Health 26(4): 251–268.
  • Zylberberg, C., K. Gaskill, S. Pasley, and S. Matosevic. 2017. “Engineering Liposomal Nanoparticles for Targeted Gene Therapy.” Gene Therapy 24(8): 441–452. doi:10.1038/gt.2017.41.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.