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Articles

Single-walled carbon nanotubes repress viral-induced defense pathways through oxidative stress

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Pages 1176-1196 | Received 07 Mar 2019, Accepted 11 Jul 2019, Published online: 27 Sep 2019

References

  • Afrooz, A. R., I. A. Khan, S. M. Hussain, and N. B. Saleh. 2013. “Mechanistic Heteroaggregation of Gold Nanoparticles in a Wide Range of Solution Chemistry.” Environmental Science & Technology 47(4):1853–1860. doi:10.1021/es3032709.
  • Aich, N., L. K. Boateng, I. V. Sabaraya, D. Das, J. R. Flora, and N. B. Saleh. 2016. “Aggregation Kinetics of Higher-Order Fullerene Clusters in Aquatic Systems.” Environmental Science & Technology 50(7):3562–3571. doi:10.1021/acs.est.5b05447.
  • Avalos, A.,. A. I. Haza, D. Mateo, and P. Morales. 2014. “Cytotoxicity and ROS Production of Manufactured Silver Nanoparticles of Different Sizes in Hepatoma and Leukemia Cells.” Journal of Applied Toxicology 34(4):413–423. doi:10.1002/jat.2957.
  • Beard, J. D., A. Erdely, M. M. Dahm, M. A. de Perio, M. E. Birch, D. E. Evans, J. E. Fernback., et al. 2018. “Carbon Nanotube and Nanofiber Exposure and Sputum and Blood Biomarkers of Early Effect among U.S. workers.” Environment International 116:214–228. doi:10.1016/j.envint.2018.04.004.
  • Bisesi, J., T. Ngo, S. Ponnavolu, K. Liu, C. Lavelle, A. R. M. Afrooz, N. Saleh, P. Ferguson, N. Denslow, and T. Sabo-Attwood. 2015. “Examination of Single-Walled Carbon Nanotubes Uptake and Toxicity from Dietary Exposure: Tracking Movement and Impacts in the Gastrointestinal System.” Nanomaterials (Basel) 5(2):1066–1086. doi:10.3390/nano5021066.
  • Buskiewicz, I. A., T. Montgomery, E. C. Yasewicz, S. A. Huber, M. P. Murphy, R. C. Hartley, R. Kelly., et al. 2016. “Reactive Oxygen Species Induce Virus-Independent MAVS Oligomerization in Systemic Lupus Erythematosus.” Science Signaling 9(456):ra115. doi:10.1126/scisignal.aaf1933.
  • Cesta, M. F., J. P. Ryman-Rasmussen, D. G. Wallace, T. Masinde, G. Hurlburt, A. J. Taylor, and J. C. Bonner. 2010. “Bacterial Lipopolysaccharide Enhances PDGF Signaling and Pulmonary Fibrosis in Rats Exposed to Carbon Nanotubes.” American Journal of Respiratory Cell and Molecular Biology 43(2):142–151. doi:10.1165/rcmb.2009-0113OC.
  • Chan, M. C. W., R. W. Y. Chan, W. C. L. Yu, C. C. C. Ho, K. M. Yuen, J. H. M. Fong, L. L. S. Tang., et al. 2010. “Tropism and Innate Host Responses of the 2009 Pandemic H1N1 Influenza Virus in Ex Vivo and in Vitro Cultures of Human Conjunctiva and Respiratory Tract.” The American Journal of Pathology 176(4):1828–1840. doi:10.2353/ajpath.2010.091087.
  • Chen, H., X. Zheng, J. Nicholas, S. T. Humes, J. C. Loeb, S. E. Robinson, J. H. Bisesi., et al. 2017. “Single-Walled Carbon Nanotubes Modulate Pulmonary Immune Responses and Increase Pandemic Influenza a Virus Titers in Mice.” Virology Journal 14(1):242. doi:10.1186/s12985-017-0909-z.
  • Clift, M. J. D., C. Endes, D. Vanhecke, P. Wick, P. Gehr, R. P. F. Schins, A. Petri-Fink, and B. Rothen-Rutishauser. 2014. “A Comparative Study of Different in Vitro Lung Cell Culture Systems to Assess the Most Beneficial Tool for Screening the Potential Adverse Effects of Carbon Nanotubes.” Toxicological Sciences 137(1):55–64. doi:10.1093/toxsci/kft216.
  • Cummins, N. W., E. A. Weaver, S. M. May, A. J. Croatt, O. Foreman, R. B. Kennedy, G. A. Poland, M. A. Barry, K. A. Nath, and A. D. Badley. 2012. “Heme Oxygenase-1 Regulates the Immune Response to Influenza Virus Infection and Vaccination in Aged Mice.” The FASEB Journal 26(7):2911–2918. doi:10.1096/fj.11-190017.
  • Dahm, M. M., M. K. Schubauer-Berigan, D. E. Evans, M. E. Birch, S. Bertke, J. D. Beard, A. Erdely, J. E. Fernback, R. R. Mercer, and S. A. Grinshpun. 2018. “Exposure Assessments for a Cross-Sectional Epidemiologic Study of US Carbon Nanotube and Nanofiber Workers.” International Journal of Hygiene and Environmental Health 221(3):429–440. doi:10.1016/j.ijheh.2018.01.006.
  • Donaldson, K., C. A. Poland, F. A. Murphy, M. MacFarlane, T. Chernova, and A. Schinwald. 2013. “Pulmonary Toxicity of Carbon Nanotubes and Asbestos – Similarities and Differences.” Advanced Drug Delivery Reviews 65(15):2078–2086. doi:10.1016/j.addr.2013.07.014.
  • Dong, J., and Q. Ma. 2015. “Advances in Mechanisms and Signaling Pathways of Carbon Nanotube Toxicity.” Nanotoxicology 9(5):658–676. doi:10.3109/17435390.2015.1009187.
  • Dong, J., and Q. Ma. 2016. “Suppression of Basal and Carbon Nanotube-Induced Oxidative Stress, Inflammation and Fibrosis in Mouse Lungs by Nrf2.” Nanotoxicology 10(6):699–709. doi:10.3109/17435390.2015.1110758.
  • Dong, J., D. W. Porter, L. A. Batteli, M. G. Wolfarth, D. L. Richardson, and Q. Ma. 2015. “Pathologic and Molecular Profiling of Rapid-Onset Fibrosis and Inflammation Induced by Multi-Walled Carbon Nanotubes.” Archives of Toxicology 89(4):621–633. doi:10.1007/s00204-014-1428-y.
  • Duffney, P. F., C. E. McCarthy, A. Nogales, T. H. Thatcher, L. Martinez-Sobrido, R. P. Phipps, and P. J. Sime. 2018. “Cigarette Smoke Dampens Antiviral Signaling in Small Airway Epithelial Cells by Disrupting TLR3 Cleavage.” American Journal of Physiology-Lung Cellular and Molecular Physiology 314(3):L505–L513. doi:10.1152/ajplung.00406.2017.
  • Duque, J. G., M. Pasquali, L. Cognet, and B. Lounis. 2009. “Environmental and Synthesis-Dependent Luminescence Properties of Individual Single-Walled Carbon Nanotubes.” ACS Nano 3(8):2153–2156. doi:10.1021/nn9003956.
  • Garigliany, M. M., and D. J. Desmecht. 2011. “N-Acetylcysteine Lacks Universal Inhibitory Activity against Influenza a Viruses.” Journal of Negative Results in Biomedicine 10(1):5. doi:10.1186/1477-5751-10-5.
  • Geiler, J., M. Michaelis, P. Naczk, A. Leutz, K. Langer, H. W. Doerr, and J. Cinatl. Jr. 2010. “N-acetyl-L-Cysteine (NAC) Inhibits Virus Replication and Expression of Pro-Inflammatory Molecules in A549 Cells Infected with Highly Pathogenic H5N1 Influenza a Virus.” Biochemical Pharmacology 79(3):413–420. doi:10.1016/j.bcp.2009.08.025.
  • Giovannini, C., P. Matarrese, B. Scazzocchio, M. Sanchez, R. Masella, and W. Malorni. 2002. “Mitochondria Hyperpolarization Is an Early Event in Oxidized Low-Density Lipoprotein-Induced Apoptosis in Caco-2 Intestinal Cells.” FEBS Letters 523(1-3):200–206. doi:10.1016/S0014-5793(02)02972-1.
  • Glick, D., S. Barth, and K. F. Macleod. 2010. “Autophagy: Cellular and Molecular Mechanisms.” The Journal of Pathology 221(1):3–12. doi:10.1002/path.2697.
  • Gowdy, K. M., Q. T. Krantz, C. King, E. Boykin, I. Jaspers, W. P. Linak, and M. I. Gilmour. 2010. “Role of Oxidative Stress on Diesel-Enhanced Influenza Infection in Mice.” Particle and Fibre Toxicology 7(1):34. doi:10.1186/1743-8977-7-34.
  • Grand View Research, GRV. 2015. Global Carbon Nanotubes (CNT) Market By Product (Single Walled Carbon Nanotubes (SWCNT), Multi Walled Carbon Nanotubes (MWCNT)), By Application (Polymers, Energy, Electrical & Electronics) Is Expected To Reach USD 3.42 Billion By 2022.
  • Griego, S. D., C. B. Weston, J. L. Adams, R. Tal-Singer, and S. B. Dillon. 2000. “Role of p38 Mitogen-Activated Protein Kinase in Rhinovirus-Induced Cytokine Production by Bronchial Epithelial Cells.” The Journal of Immunology 165(9):5211–5220. doi:10.4049/jimmunol.165.9.5211.
  • Groopman, J. D., D. Johnson, and T. W. Kensler. 2005. “Aflatoxin and Hepatitis B Virus Biomarkers: A Paradigm for Complex Environmental Exposures and Cancer Risk.” Cancer Biomarkers 1(1):5–14. doi:10.3233/CBM-2005-1103.
  • Hou, F., L. Sun, H. Zheng, B. Skaug, Q. X. Jiang, and Z. J. Chen. 2011. “MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response.” Cell 146(3):448–461. doi:10.1016/j.cell.2011.06.041.
  • Hou, J., B. Wan, Y. Yang, X. M. Ren, L. H. Guo, and J. F. Liu. 2016. “Biodegradation of Single-Walled Carbon Nanotubes in Macrophages through Respiratory Burst Modulation.” International Journal of Molecular Sciences 17(3):409. doi:10.3390/ijms17030409.
  • Ishihara, N., Y. Eura, and K. Mihara. 2004. “Mitofusin 1 and 2 Play Distinct Roles in Mitochondrial Fusion Reactions via GTPase Activity.” Journal of Cell Science 117(26):6535–6546. doi:10.1242/jcs.01565.
  • Ito, Y., K. Correll, R. L. Zemans, C. C. Leslie, R. C. Murphy, and R. J. Mason. 2015. “Influenza Induces IL-8 and GM-CSF Secretion by Human Alveolar Epithelial Cells through HGF/c-Met and TGF-Alpha/EGFR Signaling.” American Journal of Physiology-Lung Cellular and Molecular Physiology 308(11):L1178–1188. doi:10.1152/ajplung.00290.2014.
  • Jacobs, J. L., J. Zhu, S. N. Sarkar, and C. B. Coyne. 2014. “Regulation of Mitochondrial Antiviral Signaling (MAVS) Expression and Signaling by the Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Protein Gp78.” Journal of Biological Chemistry 289(3):1604–1616. doi:10.1074/jbc.M113.520254.
  • Jaspers, I., P. A. Sheridan, W. Zhang, L. E. Brighton, K. D. Chason, X. Hua, and S. L. Tilley. 2009. “Exacerbation of Allergic Inflammation in Mice Exposed to Diesel Exhaust Particles Prior to Viral Infection.” Particle and Fibre Toxicology 6(1):22. doi:10.1186/1743-8977-6-22.
  • Jorgensen, S. E., M. Christiansen, L. B. Ryo, H. H. Gad, J. Gjedsted, P. Staeheli, and T. H. Mogensen. 2018. “Defective RNA Sensing by RIG-I in Severe Influenza Virus Infection.” Clinical & Experimental Immunology 192(3):366–376. doi:10.1111/cei.13120.
  • Khan, I. A., A. R. Afrooz, J. R. Flora, P. A. Schierz, P. L. Ferguson, T. Sabo-Attwood, and N. B. Saleh. 2013. “Chirality Affects Aggregation Kinetics of Single-Walled Carbon Nanotubes.” Environmental Science & Technology 47(4):1844–1852. doi:10.1021/es3030337.
  • Kim, J. S., and I. J. Yu. 2014. “Single-Wall Carbon Nanotubes (SWCNT) Induce Cytotoxicity and Genotoxicity Produced by Reactive Oxygen Species (ROS) Generation in Phytohemagglutinin (PHA)-Stimulated Male Human Peripheral Blood Lymphocytes.” Journal of Toxicology and Environmental Health A 77(19):1141–1153. doi:10.1080/15287394.2014.917062.
  • Kisin, E. R., A. R. Murray, L. Sargent, D. Lowry, M. Chirila, K. J. Siegrist, D. Schwegler-Berry, et al. 2011. “Genotoxicity of Carbon Nanofibers: Are They Potentially More or Less Dangerous Than Carbon Nanotubes or Asbestos?” Toxicology and Applied Pharmacology 252(1):1–10. doi:10.1016/j.taap.2011.02.001.
  • Koshiba, T., K. Yasukawa, Y. Yanagi, and S. Kawabata. 2011. “Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling.” Science Signaling 4(158):ra7. doi:10.1126/scisignal.2001147.
  • Kotchey, G. P., S. A. Hasan, A. A. Kapralov, S. H. Ha, K. Kim, A. A. Shvedova, V. E. Kagan, and A. Star. 2012. “A Natural Vanishing Act: The Enzyme-Catalyzed Degradation of Carbon Nanomaterials.” Accounts of Chemical Research 45(10):1770–1781. doi:10.1021/ar300106h.
  • Kouassi, S., C. Catto, C. Ostiguy, G. L’Espérance, J. Kroeger, and M. Debia. 2017. “Exposure Assessment in a Single-Walled Carbon Nanotube Primary Manufacturer.” Annals of Work Exposures and Health 61(2):260–266. doi:10.1093/annweh/wxw017.
  • LeVine, A. M., J. A. Whitsett, K. L. Hartshorn, E. C. Crouch, and T. R. Korfhagen. 2001. “Surfactant Protein D Enhances Clearance of Influenza a Virus from the Lung in Vivo.” Journal of Immunology (Baltimore, MD: 1950) 167(10):5868–5873. doi:10.4049/jimmunol.167.10.5868.
  • Levonen, A.-L., E. VäHäKangas, J. K. Koponen, and S. Ylä-Herttuala, 2008. “Antioxidant Gene Therapy for Cardiovascular Disease: Current Status and Future Perspectives.” Circulation 117(16):2142–2150. doi:10.1161/CIRCULATIONAHA.107.718585.
  • Liao, H.-Y., Y.-T. Chung, C.-H. Lai, S.-L. Wang, H.-C. Chiang, L.-A. Li, T.-C. Tsou., et al. 2014. “Six-Month Follow-up Study of Health Markers of Nanomaterials among Workers Handling Engineered Nanomaterials.” Nanotoxicology 8(sup1):100–110. doi:10.3109/17435390.2013.858793.
  • Liu, Y., Y. Zhao, B. Sun, and C. Chen. 2013. “Understanding the Toxicity of Carbon Nanotubes.” Accounts of Chemical Research 46(3):702–713. doi:10.1021/ar300028m.
  • Livak, K. J., and T. D. Schmittgen. 2001. “Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2(-Delta Delta C(T)) Method.” Methods 25(4):402–408. doi:10.1006/meth.2001.1262.
  • Martin, C. R., and P. Kohli. 2003. “The Emerging Field of Nanotube Biotechnology.” Nature Reviews Drug Discovery 2(1):29–37. doi:10.1038/nrd988.
  • Matarrese, P., L. Gambardella, A. Cassone, S. Vella, R. Cauda, and W. Malorni. 2003. “Mitochondrial Membrane Hyperpolarization Hijacks Activated T Lymphocytes toward the Apoptotic-Prone Phenotype: Homeostatic Mechanisms of HIV Protease Inhibitors.” [Comparative Study]. The Journal of Immunology 170(12):6006–6015. doi:10.4049/jimmunol.170.12.6006.
  • Matera, M. G., L. Calzetta, and M. Cazzola. 2016. “Oxidation Pathway and Exacerbations in COPD: The Role of NAC.” Expert Review of Respiratory Medicine 10(1):89–97. doi:10.1586/17476348.2016.1121105.
  • Meng, J., X. Li, C. Wang, H. Guo, J. Liu, and H. Xu. 2015. “Carbon Nanotubes Activate Macrophages into a M1/M2 Mixed Status: Recruiting Naive Macrophages and Supporting Angiogenesis.” ACS Applied Materials & Interfaces 7(5):3180–3188. doi:10.1021/am507649n.
  • Mrakovcic, M.,. C. Meindl, G. Leitinger, E. Roblegg, and E. Frohlich. 2015. “Carboxylated Short Single-Walled Carbon Nanotubes but Not Plain and Multi-Walled Short Carbon Nanotubes Show in Vitro Genotoxicity.” Toxicological Sciences 144(1):114–127. doi:10.1093/toxsci/kfu260.
  • Nagy, G., A. Koncz, D. Fernandez, and A. Perl. 2007. “Nitric Oxide, Mitochondrial Hyperpolarization, and T Cell Activation.” Free Radical Biology and Medicine 42(11):1625–1631. doi:10.1016/j.freeradbiomed.2007.02.026.
  • Naserzadeh, P., F. Ansari Esfeh, M. Kaviani, K. Ashtari, R. Kheirbakhsh, A. Salimi, and J. Pourahmad. 2018. “Single-Walled Carbon Nanotube, Multi-Walled Carbon Nanotube and Fe2O3 Nanoparticles Induced Mitochondria Mediated Apoptosis in Melanoma Cells.” Cutaneous and Ocular Toxicology 37(2):157–166. doi:10.1080/15569527.2017.1363227.
  • Okumura, A., A. L. Rasmussen, P. Halfmann, F. Feldmann, A. Yoshimura, H. Feldmann, Y. Kawaoka, R. N. Harty, and M. G. Katze. 2015. “Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection.” Journal of Virology 89(20):10399–10406. doi:10.1128/JVI.01736-15.
  • Park, E. J., Y. S. Hong, B. S. Lee, C. Yoon, U. Jeong, and Y. Kim. 2016. “Single-Walled Carbon Nanotubes Disturbed the Immune and Metabolic Regulation Function 13-Weeks after a Single Intratracheal Instillation.” Environmental Research 148:184–195. doi:10.1016/j.envres.2016.03.027.
  • Park, E. J., N. E. Zahari, E. W. Lee, J. Song, J. H. Lee, M. H. Cho, and J. H. Kim. 2014. “SWCNTs Induced Autophagic Cell Death in Human Bronchial Epithelial Cells.” Toxicology in Vitro 28(3):442–450. doi:10.1016/j.tiv.2013.12.012.
  • Piao, C. Q., L. Liu, Y. L. Zhao, A. S. Balajee, M. Suzuki, and T. K. Hei. 2005. “Immortalization of Human Small Airway Epithelial Cells by Ectopic Expression of Telomerase.” Carcinogenesis 26(4):725–731. doi:10.1093/carcin/bgi016.
  • Pielak, R. M., and J. J. Chou. 2011. “Influenza M2 Proton Channels.” Biochimica et Biophysica Acta (BBA) Biomembranes 1808(2):522–529. doi:10.1016/j.bbamem.2010.04.015.
  • Pyo, C. W., N. Shin, K. I. Jung, J. H. Choi, and S. Y. Choi. 2014. “Alteration of Copper-Zinc Superoxide Dismutase 1 Expression by Influenza a Virus Is Correlated with Virus Replication.” Biochemical and Biophysical Research Communications 450(1):711–716. doi:10.1016/j.bbrc.2014.06.037.
  • Qi, X., H. Zhang, T. Xue, B. Yang, M. Deng, and J. Wang. 2018. “Down-Regulation of Cellular Protein Heme Oxygenase-1 Inhibits Proliferation of Avian Influenza Virus H9N2 in Chicken Oviduct Epithelial Cells.” Journal of General Virology 99(1):36–43. doi:10.1099/jgv.0.000986.
  • Qian, G. S., R. K. Ross, M. C. Yu, J. M. Yuan, Y. T. Gao, B. E. Henderson, and J. D. Groopman. 1994. “A Follow-up Study of Urinary Markers of Aflatoxin Exposure and Liver Cancer Risk in Shanghai, People's Republic of China.” Cancer Epidemiology, Biomarkers & Prevention 3(1):3–10.
  • Qin, Y., S. Li, G. Zhao, X. Fu, X. Xie, Y. Huang, X. Cheng, J. Wei, H. Liu, and Z. Lai. 2016. “Long-Term Intravenous Administration of Carboxylated Single-Walled Carbon Nanotubes Induces Persistent Accumulation in the Lungs and Pulmonary Fibrosis via the Nuclear Factor-Kappa B Pathway.” International Journal of Nanomedicine 12:263–277. doi:10.2147/IJN.S123839.
  • Rowe, T., D. Banner, A. Farooqui, D. C. K. Ng, A. A. Kelvin, S. Rubino, S. S. H. Huang, Y. Fang, and D. J. Kelvin. 2010. “In Vivo Ribavirin Activity against Severe Pandemic H1N1 Influenza a/Mexico/4108/2009.” Journal of General Virology 91(12):2898–2906. doi:10.1099/vir.0.024323-0.
  • Sanpui, P., X. Zheng, J. C. Loeb, J. H. Bisesi Jr, I. A. Khan, A. R. M. N. Afrooz, K. Liu., et al. 2014. “Single-Walled Carbon Nanotubes Increase Pandemic Influenza a H1N1 Virus Infectivity of Lung Epithelial Cells.” Particle and Fibre Toxicology 11(1):66. doi:10.1186/s12989-014-0066-0.
  • Sattler, C., F. Moritz, S. Chen, B. Steer, D. Kutschke, M. Irmler, J. Beckers., et al. 2017. “Nanoparticle Exposure Reactivates Latent Herpesvirus and Restores a Signature of Acute Infection.” Particle and Fibre Toxicology 14(1):2. doi:10.1186/s12989-016-0181-1.
  • Shvedova, A. A., J. P. Fabisiak, E. R. Kisin, A. R. Murray, J. R. Roberts, Y. Y. Tyurina, J. M. Antonini., et al. 2008. “Sequential Exposure to Carbon Nanotubes and Bacteria Enhances Pulmonary Inflammation and Infectivity.” American Journal of Respiratory Cell and Molecular Biology 38(5):579–590. doi:10.1165/rcmb.2007-0255OC.
  • Shvedova, A. A., E. R. Kisin, R. Mercer, A. R. Murray, V. J. Johnson, A. I. Potapovich, Y. Y. Tyurina., et al. 2005. “Unusual Inflammatory and Fibrogenic Pulmonary Responses to Single-Walled Carbon Nanotubes in Mice.” American Journal of Physiology-Lung Cellular and Molecular Physiology 289(5):L698–708. doi:10.1152/ajplung.00084.2005.
  • Shvedova, A. A., E. R. Kisin, D. Porter, P. Schulte, V. E. Kagan, B. Fadeel, and V. Castranova. 2009. “Mechanisms of Pulmonary Toxicity and Medical Applications of Carbon Nanotubes: Two Faces of Janus?” Pharmacology & Therapeutics 121(2):192–204. doi:10.1016/j.pharmthera.2008.10.009.
  • Shvedova, A. A., A. Pietroiusti, B. Fadeel, and V. E. Kagan. 2012. “Mechanisms of Carbon Nanotube-Induced Toxicity: Focus on Oxidative Stress.” Toxicology and Applied Pharmacology 261(2):121–133. doi:10.1016/j.taap.2012.03.023.
  • Sturm, R. 2014. “Clearance of Carbon Nanotubes in the Human Respiratory Tract – A Theoretical Approach.” Annals of Translational Medicine 2(5):46. doi:10.3978/j.issn.2305-5839.2014.04.12.
  • Turabekova, M., B. Rasulev, M. Theodore, J. Jackman, D. Leszczynska, and J. Leszczynski. 2014. “Immunotoxicity of Nanoparticles: A Computational Study Suggests That CNTs and C60 Fullerenes Might Be Recognized as Pathogens by Toll-like Receptors.” Nanoscale 6(7):3488–3495. doi:10.1039/C3NR05772K.
  • Varga, Z. T., A. Grant, B. Manicassamy, and P. Palese. 2012. “Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon by Binding to MAVS and Decreasing Mitochondrial Membrane Potential.” Journal of Virology 86(16):8359–8366. doi:10.1128/JVI.01122-12.
  • Villeret, B., A. Dieu, M. Straube, B. Solhonne, P. Miklavc, S. Hamadi, R. Le Borgne., et al. 2018. “Silver Nanoparticles Impair Retinoic Acid-Inducible Gene I-Mediated Mitochondrial Antiviral Immunity by Blocking the Autophagic Flux in Lung Epithelial Cells.” ACS Nano 12(2):1188–1202. doi:10.1021/acsnano.7b06934.
  • Walling, B. E., Z. Kuang, Y. Hao, D. Estrada, J. D. Wood, F. Lian, L. A. Miller., et al. 2013. “Helical Carbon Nanotubes Enhance the Early Immune Response and Inhibit Macrophage-Mediated Phagocytosis of Pseudomonas aeruginosa.” PLoS One 8(11):e80283. doi:10.1371/journal.pone.0080283.
  • Yatmaz, S., H. J. Seow, R. C. Gualano, Z. X. Wong, J. Stambas, S. Selemidis, P. J. Crack, S. Bozinovski, G. P. Anderson, and R. Vlahos. 2013. “Glutathione Peroxidase-1 Reduces Influenza a Virus-Induced Lung Inflammation.” American Journal of Respiratory Cell and Molecular Biology 48(1):17–26. doi:10.1165/rcmb.2011-0345OC.
  • Zamoiskii, E. A. 1956. “Evaluation of Reed-Muench Method in Determination of Activity of Biological Preparations.” Zhurnal mikrobiologii, epidemiologii, i immunobiologii 27(1):77–83.
  • Zeinabad, H. A., A. Zarrabian, A. A. Saboury, A. M. Alizadeh, and M. Falahati. 2016. “Interaction of Single and Multi Wall Carbon Nanotubes with the Biological Systems: Tau Protein and PC12 Cells as Targets.” Scientific Reports 6(1):26508. doi:10.1038/srep26508.
  • Zorov, D. B., M. Juhaszova, and S. J. Sollott. 2014. “Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release.” Physiological Reviews 94(3):909–950. doi:10.1152/physrev.00026.2013.
  • Zorova, L. D., V. A. Popkov, E. Y. Plotnikov, D. N. Silachev, I. B. Pevzner, S. S. Jankauskas, and D. B. Zorov. 2017. “Mitochondrial Membrane Potential.” Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology 552:50–59. doi:10.1016/j.ab.2017.07.009.

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