144
Views
7
CrossRef citations to date
0
Altmetric
Articles

Mechanisms of nanotoxicity – biomolecule coronas protect pathological fungi against nanoparticle-based eradication

, , , , , , , & show all
Pages 1157-1174 | Received 16 Apr 2020, Accepted 10 Jul 2020, Published online: 24 Aug 2020

References

  • Aimanianda, V., J. Bayry, S. Bozza, O. Kniemeyer, K. Perruccio, S. R. Elluru, C. Clavaud, et al. 2009. “Surface Hydrophobin Prevents Immune Recognition of Airborne Fungal Spores.” Nature 460 (7259): 1117–1121. doi:10.1038/nature08264.
  • Alarcon, E., C. Bueno-Alejo, C. Noel, K. Stamplecoskie, N. Pacioni, H. Poblete, and J. C. Scaiano. 2013. “Human Serum Albumin as Protecting Agent of Silver Nanoparticles: Role of the Protein Conformation and Amine Groups in the Nanoparticle Stabilization.” Journal of Nanoparticle Research 15 (1): 14. doi:10.1007/s11051-012-1374-7.
  • Bier, C., S. K. Knauer, A. Klapthor, A. Schweitzer, A. Rekik, O. H. Kramer, R. Marschalek, and R. H. Stauber. 2011. “Cell-Based Analysis of Structure-Function Activity of Threonine Aspartase 1.” The Journal of Biological Chemistry 286 (4): 3007–3017. doi:10.1074/jbc.M110.161646.
  • Bigdeli, A., S. Palchetti, D. Pozzi, M. R. Hormozi-Nezhad, F. Baldelli Bombelli, G. Caracciolo, and M. Mahmoudi. 2016. “Exploring Cellular Interactions of Liposomes Using Protein Corona Fingerprints and Physicochemical Properties.” ACS Nano 10 (3): 3723–3737. doi:10.1021/acsnano.6b00261.
  • Bongomin, F., S. Gago, R. O. Oladele, and D. W. Denning. 2017. “Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision.” J Fungi 3 (4): 1–29.
  • Bruns, S., O. Kniemeyer, M. Hasenberg, V. Aimanianda, S. Nietzsche, A. Thywissen, A. Jeron, J.-P. Latgé, A. A. Brakhage, and M. Gunzer. 2010. “Production of Extracellular Traps against Aspergillus fumigatus in Vitro and in Infected Lung Tissue is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA.” PLoS Pathogens 6 (4): e1000873. doi:10.1371/journal.ppat.1000873.
  • Chandran, P., J. E. Riviere, and N. A. Monteiro-Riviere. 2017. “Surface Chemistry of Gold Nanoparticles Determines the Biocorona Composition Impacting Cellular Uptake, Toxicity and Gene Expression Profiles in Human Endothelial cells.” Nanotoxicology 11 (4): 507–519. doi:10.1080/17435390.2017.1314036.
  • Choi, K., J. E. Riviere, and N. A. Monteiro-Riviere. 2017. “Protein Corona Modulation of Hepatocyte Uptake and Molecular Mechanisms of Gold Nanoparticle Toxicity.” Nanotoxicology 11 (1): 64–75. doi:10.1080/17435390.2016.1264638.
  • Courtney, C. M., S. M. Goodman, J. A. McDaniel, N. E. Madinger, A. Chatterjee, and P. Nagpal. 2016. “Photoexcited Quantum Dots for Killing Multidrug-Resistant Bacteria.” Nature Materials 15 (5): 529–534. doi:10.1038/nmat4542.
  • Dean, R., J. A. Van Kan, Z. A. Pretorius, K. E. Hammond-Kosack, A. Di Pietro, P. D. Spanu, J. J. Rudd, et al. 2012. “The Top 10 Fungal Pathogens in Molecular Plant Pathology.” Molecular Plant Pathology 13 (4): 414–430. doi:10.1111/j.1364-3703.2011.00783.x.
  • Del Pino, P., B. Pelaz, Q. Zhang, P. Maffre, G. U. Nienhaus, and W. J. Parak. 2014. “Protein Corona Formation around Nanoparticles - from the past to the Future.” Materials Horizons 1 (3): 301–313. doi:10.1039/C3MH00106G.
  • Docter, D., D. Westmeier, M. Markiewicz, S. Stolte, S. K. Knauer, and R. H. Stauber. 2015. “The Nanoparticle Biomolecule Corona: Lessons Learned - Challenge Accepted?” Chemical Society Reviews 44 (17): 6094–6121. doi:10.1039/c5cs00217f.
  • Docter, D., S. Strieth, D. Westmeier, O. Hayden, M. Gao, S. K. Knauer, and R. H. Stauber. 2015. “No King without a crown-impact of the nanomaterial-protein corona on nanobiomedicine.” Nanomedicine 10 (3): 503–519. doi:10.2217/nnm.14.184.
  • Docter, D., U. Distler, W. Storck, J. Kuharev, D. Wunsch, A. Hahlbrock, S. K. Knauer, S. Tenzer, and R. H. Stauber. 2014. “Quantitative Profiling of the Protein Coronas That Form around Nanoparticles.” Nature Protocols 9 (9): 2030–2044. doi:10.1038/nprot.2014.139.
  • Engels, K., S. K. Knauer, S. Loibl, V. Fetz, P. Harter, A. Schweitzer, A. Fisseler-Eckhoff, et al. 2008. “No Signaling Confers Cytoprotectivity through the Survivin Network in Ovarian Carcinomas.” Cancer Research 68 (13): 5159–5166. doi:10.1158/0008-5472.CAN-08-0406.
  • Erwig, L. P., and N. A. Gow. 2016. “Interactions of Fungal Pathogens with Phagocytes.” Nature Reviews. Microbiology 14 (3): 163–176. doi:10.1038/nrmicro.2015.21.
  • Gao, Z., T. Ma, E. Zhao, D. Docter, W. Yang, R. H. Stauber, and M. Gao. 2016. “Small is Smarter: Nano MRI Contrast Agents - Advantages and Recent Achievements. Small.” Small 12 (5): 556–576. doi:10.1002/smll.201502309.
  • Gebauer, J. S., M. Malissek, S. Simon, S. K. Knauer, M. Maskos, R. H. Stauber, W. Peukert, and L. Treuel. 2012. “Impact of the Nanoparticle-Protein Corona on Colloidal Stability and Protein Structure.” Langmuir: The ACS Journal of Surfaces and Colloids 28 (25): 9673–9679. doi:10.1021/la301104a.
  • Gomez-Lopez, A., A. Forastiero, E. Cendejas-Bueno, L. Gregson, E. Mellado, S. J. Howard, J. L. Livermore, W. W. Hope, and M. Cuenca-Estrella. 2014. “An Invertebrate Model to Evaluate Virulence in Aspergillus fumigatus: The Role of Azole Resistance.” Medical Mycology 52 (3): 311–319. doi:10.1093/mmy/myt022.
  • Gribko, A., J. Kunzel, D. Wunsch, Q. Lu, S. M. Nagel, S. K. Knauer, R. H. Stauber, and G. B. Ding. 2019. “Is Small Smarter? Nanomaterial-Based Detection and Elimination of Circulating Tumor Cells: Current Knowledge and Perspectives.” International Journal of Nanomedicine 14: 4187–4209. doi:10.2147/IJN.S198319.
  • Hajipour, M. J., K. M. Fromm, A. A. Ashkarran, D. Jimenez de Aberasturi, I. R. de Larramendi, T. Rojo, V. Serpooshan, W. J. Parak, and M. Mahmoudi. 2012. “Antibacterial Properties of Nanoparticles.” Trends in Biotechnology 30 (10): 499–511. doi:10.1016/j.tibtech.2012.06.004.
  • Halbus, A. F., T. S. Horozov, and V. N. Paunov. 2017. “Colloid Particle Formulations for Antimicrobial Applications.” Advances in Colloid and Interface Science 249: 134–148. doi:10.1016/j.cis.2017.05.012.
  • Hamprecht, A., F. Morio, O. Bader, P. Le Pape, J. Steinmann, and E. Dannaoui. 2018. “Azole Resistance in Aspergillus fumigatus in Patients with Cystic Fibrosis: A Matter of Concern?” Mycopathologia 183 (1): 151–160. doi:10.1007/s11046-017-0162-4.
  • Holm, R., B. Weber, P. Heller, K. Klinker, D. Westmeier, D. Docter, R. H. Stauber, and M. Barz. 2017. “Synthesis and Characterization of Stimuli-Responsive Star-Like Polypept(o)Ides: Introducing Biodegradable PeptoStars.” Macromolecular Bioscience. 17 (6): 1600514.
  • Huh, A. J., and Y. J. Kwon. 2011. “‘Nanoantibiotics’: A New Paradigm for Treating Infectious Diseases using Nanomaterials in the Antibiotics Resistant Era.” Journal of Controlled Release: Official Journal of the Controlled Release Society 156 (2): 128–145. doi:10.1016/j.jconrel.2011.07.002.
  • Jiang, L., M. K. Greene, J. L. Insua, J. S. Pessoa, D. M. Small, P. Smyth, A. P. McCann, et al. 2018. “Clearance of Intracellular Klebsiella pneumoniae Infection Using Gentamicin-Loaded Nanoparticles.” Journal of Controlled Release: Official Journal of the Controlled Release Society 279: 316–325. doi:10.1016/j.jconrel.2018.04.040.
  • Kasprzyk, I. 2008. “Aeromycology–Main Research Fields of Interest during the Last 25 Years.” Annals of Agricultural and Environmental Medicine 15 (1): 1–7.
  • Knauer, S. K., S. Moodt, T. Berg, U. Liebel, R. Pepperkok, and R. H. Stauber. 2005. “Translocation Biosensors to Study Signal-Specific Nucleo-Cytoplasmic Transport, Protease Activity and Protein-Protein Interactions.” Traffic 6 (7): 594–606. doi:10.1111/j.1600-0854.2005.00298.x.
  • Kopp, M., S. Kollenda, and M. Epple. 2017. “Nanoparticle-Protein Interactions: Therapeutic Approaches and Supramolecular Chemistry.” Accounts of Chemical Research 50 (6): 1383–1390. doi:10.1021/acs.accounts.7b00051.
  • Koshkina, O., D. Westmeier, T. Lang, C. Bantz, A. Hahlbrock, C. Wurth, et al. 2016. “Tuning the Surface of Nanoparticles: Impact of Poly(2-Ethyl-2-Oxazoline) on Protein Adsorption in Serum and Cellular Uptake.” Macromolecular Bioscience 16 (9): 1287–1300. doi:10.1002/mabi.201600074.
  • Kunzel, J., A. Gribko, Q. Lu, R. Stauber, and D. Wunsch. 2019. “Nanomedical Detection and Downstream Analysis of Circulating Tumor Cells in Head and Neck Patients.” Biological Chemistry 400 (11): 1465–1479. doi:10.1515/hsz-2019-0141.
  • Lam, S. J., N. M. O’Brien-Simpson, N. Pantarat, A. Sulistio, E. H. Wong, Y. Y. Chen, J. C. Lenzo, et al. 2016. “Combating Multidrug-Resistant Gram-Negative Bacteria with Structurally Nanoengineered Antimicrobial Peptide Polymers.” Nature Microbiology 1 (11): 16162. doi:10.1038/nmicrobiol.2016.162.
  • Lan, M., J. Wu, W. Liu, W. Zhang, J. Ge, H. Zhang, J. Sun, W. Zhao, and P. Wang. 2012. “Copolythiophene-derived colorimetric and fluorometric sensor for visually supersensitive determination of lipopolysaccharide.” Journal of the American Chemical Society 134 (15): 6685–6694. doi:10.1021/ja211570a.
  • Li, J., H. Sang, H. Guo, J. T. Popko, L. He, J. C. White, O. Parkash Dhankher, G. Jung, and B. Xing. 2017. “Antifungal Mechanisms of ZnO and Ag Nanoparticles to Sclerotinia Homoeocarpa.” Nanotechnology 28 (15): 155101. doi:10.1088/1361-6528/aa61f3.
  • Li, X., S. M. Robinson, A. Gupta, K. Saha, Z. Jiang, D. F. Moyano, A. Sahar, M. A. Riley, and V. M. Rotello. 2014. “Functional Gold Nanoparticles as Potent Antimicrobial Agents against Multi-Drug-Resistant Bacteria.” ACS Nano 8 (10): 10682–10686. doi:10.1021/nn5042625.
  • Liermann, J. C., H. Kolshorn, T. Opatz, E. Thines, and H. Anke. 2009. “Xanthepinone, an Antimicrobial Polyketide from a Soil Fungus Closely Related to Phoma Medicaginis.” Journal of Natural Products 72 (10): 1905–1907. doi:10.1021/np9005234.
  • Liu, R., W. Jiang, C. D. Walkey, W. C. Chan, and Y. Cohen. 2015. “Prediction of Nanoparticles-Cell Association Based on Corona Proteins and Physicochemical Properties.” Nanoscale 7 (21): 9664–9675. doi:10.1039/c5nr01537e.
  • Markiewicz, M., J. Kumirska, I. Lynch, M. Matzke, J. Koser, S. Bemowsky, D. Docter, R. Stauber, D. Westmeier, and S. Stolte. 2018. “Changing Environments and Biomolecule Coronas: Consequences and Challenges for the Design of Environmentally Acceptable Engineered Nanoparticles.” Green Chemistry 20 (18): 4133–4168. doi:10.1039/C8GC01171K.
  • Martin, J. J. C., M. Assali, E. Fernandez-Garcia, V. Valdivia, E. M. Sanchez-Fernandez, J. M. G. Fernandez, R. E. Wellinger, I. Fernandez, and N. Khiar. 2016. “Tuning of Glyconanomaterial Shape and Size for Selective Bacterial Cell Agglutination.” Journal of Materials Chemistry. B 4 (11): 2028–2037. doi:10.1039/c5tb02488a.
  • Monteiro-Riviere, N. A., M. E. Samberg, S. J. Oldenburg, and J. E. Riviere. 2013. “Protein Binding Modulates the Cellular Uptake of Silver Nanoparticles into Human Cells: Implications for in Vitro to in Vivo Extrapolations?” Toxicology Letters. 220 (3): 286–293. doi:10.1016/j.toxlet.2013.04.022.
  • Muller, M. K., and L. Brunsveld. 2009. “A Supramolecular Polymer as a Self-Assembling Polyvalent Scaffold.” Angewandte Chemie 48 (16): 2921–2924. doi:10.1002/anie.200900143.
  • Ortega, M. T., J. E. Riviere, K. Choi, and N. A. Monteiro-Riviere. 2017. “Biocorona Formation on Gold Nanoparticles Modulates Human Proximal Tubule Kidney Cell Uptake, Cytotoxicity and Gene Expression.” Toxicology in Vitro: An International Journal Published in Association with BIBRA 42: 150–160. doi:10.1016/j.tiv.2017.04.020.
  • Panacek, A., M. Kolar, R. Vecerova, R. Prucek, J. Soukupova, V. Krystof, P. Hamal, R. Zboril, and L. Kvitek. 2009. “Antifungal Activity of Silver Nanoparticles against Candida Spp.” Biomaterials 30 (31): 6333–6340. doi:10.1016/j.biomaterials.2009.07.065.
  • Parveen, S., A. H. Wani, M. A. Shah, H. S. Devi, M. Y. Bhat, and J. A. Koka. 2018. “Preparation, Characterization and Antifungal Activity of Iron Oxide Nanoparticles.” Microbial Pathogenesis 115: 287–292. doi:10.1016/j.micpath.2017.12.068.
  • Passera, E., A. Rizzi, M. Robustellini, G. Rossi, C. Della Pona, F. Massera, and G. Rocco. 2012. “Pulmonary Aspergilloma: Clinical Aspects and Surgical Treatment Outcome.” Thoracic Surgery Clinics 22 (3): 345–361. doi:10.1016/j.thorsurg.2012.04.001.
  • Paulo, C. S., M. Vidal, and L. S. Ferreira. 2010. “Antifungal Nanoparticles and Surfaces.” Biomacromolecules 11 (10): 2810–2817. doi:10.1021/bm100893r.
  • Radwan, M. A., B. T. AlQuadeib, L. Siller, M. C. Wright, and B. Horrocks. 2017. “Oral Administration of Amphotericin B Nanoparticles: Antifungal Activity, Bioavailability and Toxicity in Rats.” Drug Delivery 24 (1): 40–50. doi:10.1080/10717544.2016.1228715.
  • Raghupathi, K. R., R. T. Koodali, and A. C. Manna. 2011. “Size-Dependent Bacterial Growth Inhibition and Mechanism of Antibacterial Activity of Zinc Oxide Nanoparticles.” Langmuir: The ACS Journal of Surfaces and Colloids 27 (7): 4020–4028. doi:10.1021/la104825u.
  • Rai, M., A. Yadav, and A. Gade. 2009. “Silver Nanoparticles as a New Generation of Antimicrobials.” Biotechnology Advances 27 (1): 76–83. doi:10.1016/j.biotechadv.2008.09.002.
  • Ramarao, N., C. Nielsen-Leroux, and D. Lereclus. 2012. “The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis.” Journal of Visualized Experience 70 (70): e4392.
  • Ritz, U., H. Gotz, A. Baranowski, F. Heid, P. M. Rommens, and A. Hofmann. 2017. “Influence of Different Calcium Phosphate Ceramics on Growth and Differentiation of Cells in Osteoblast-Endothelial co-Cultures.” Journal of Biomedical Materials Research. Part B, Applied Biomaterials 105 (7): 1950–1962. doi:10.1002/jbm.b.33728.
  • Riviere, J. E., C. Scoglio, F. D. Sahneh, and N. A. Monteiro-Riviere. 2013. “Computational Approaches and Metrics Required for Formulating Biologically Realistic Nanomaterial Pharmacokinetic Models.” Computational Science & Discovery 6 (1): 014005. doi:10.1088/1749-4699/6/1/014005.
  • Riviere, J. E., M. Jaberi-Douraki, J. Lillich, T. Azizi, H. Joo, K. Choi, R. Thakkar, and N. A. Monteiro-Riviere. 2018. “Modeling Gold Nanoparticle Biodistribution after Arterial Infusion into Perfused Tissue: Effects of Surface Coating, Size and Protein Corona.” Nanotoxicology 12 (10): 1093–1112. doi:10.1080/17435390.2018.1476986.
  • Roling, M. A., N. M. Mathijssen, and R. M. Bloem. 2016. “Incidence of Symptomatic Femoroacetabular Impingement in the General Population: A Prospective Registration Study.” Journal of Hip Preservation Surgery 3 (3): 203–207. doi:10.1093/jhps/hnw009.
  • Rolle, A. M., M. Hasenberg, C. R. Thornton, D. Solouk-Saran, L. Mann, J. Weski, A. Maurer, et al. 2016. “ImmunoPET/MR Imaging Allows Specific Detection of Aspergillus fumigatus Lung Infection in Vivo.” Proceedings of the National Academy of Sciences of the United States of America 113 (8): E1026–E1033. doi:10.1073/pnas.1518836113.
  • Romani, L. 2011. “Immunity to Fungal Infections.” Nature Reviews. Immunology 11 (4): 275–288. doi:10.1038/nri2939.
  • Sankaran, S., J. van Weerd, J. Voskuhl, M. Karperien, and P. Jonkheijm. 2015. “Photoresponsive Cucurbit[8]uril-Mediated Adhesion of Bacteria on Supported Lipid Bilayers.” Small 11 (46): 6187–6196. doi:10.1002/smll.201502471.
  • Schmidt, B., S. Sankaran, L. Stegemann, C. A. Strassert, P. Jonkheijm, and J. Voskuhl. 2016. “Agglutination of Bacteria Using Polyvalent Nanoparticles of Aggregation-Induced Emissive Thiophthalonitrile Dyes.” Journal of Materials Chemistry. B 4 (27): 4732–4738. doi:10.1039/c6tb01210h.
  • Shvedova, A. A., J. P. Fabisiak, E. R. Kisin, A. R. Murray, J. R. Roberts, Y. Y. Tyurina, J. M. Antonini, et al. 2008. “Sequential Exposure to Carbon Nanotubes and Bacteria Enhances Pulmonary Inflammation and Infectivity.” American Journal of Respiratory Cell and Molecular Biology 38 (5): 579–590. doi:10.1165/rcmb.2007-0255OC.
  • Siemer, S., A. Hahlbrock, C. Vallet, D. J. McClements, J. Balszuweit, J. Voskuhl, D. Docter, et al. 2018. “Nanosized Food Additives Impact Beneficial and Pathogenic Bacteria in the Human Gut: A Simulated Gastrointestinal Study.” NPJ Science of Food 2 (1): 22. doi:10.1038/s41538-018-0030-8.
  • Siemer, S., D. Westmeier, C. Vallet, J. Steinmann, J. Buer, R. H. Stauber, and S. K. Knauer. 2018. “Breaking Resistance to Nanoantibiotics by Overriding Corona-Dependent Inhibition Using a pH-Switch.” Materials Today 26: 19–29. doi:10.1016/j.mattod.2018.10.041.
  • Siemer, S., D. Westmeier, M. Barz, J. Eckrich, D. Wunsch, C. Seckert, C. Thyssen, et al. 2019. “Biomolecule-Corona Formation Confers Resistance of Bacteria to Nanoparticle-Induced Killing: Implications for the Design of Improved Nanoantibiotics.” Biomaterials 192: 551–559. doi:10.1016/j.biomaterials.2018.11.028.
  • Sierra-Fernandez, A., S. C. De la Rosa-Garcia, L. S. Gomez-Villalba, S. Gomez-Cornelio, M. E. Rabanal, R. Fort, and P. Quintana. 2017. “Synthesis, Photocatalytic, and Antifungal Properties of MgO, ZnO and Zn/Mg Oxide Nanoparticles for the Protection of Calcareous Stone Heritage.” ACS Applied Materials & Interfaces 9 (29): 24873–24886. doi:10.1021/acsami.7b06130.
  • Soliman, G. M. 2017. “Nanoparticles as Safe and Effective Delivery Systems of Antifungal Agents: Achievements and Challenges.” International Journal of Pharmaceutics 523 (1): 15–32. doi:10.1016/j.ijpharm.2017.03.019.
  • Stauber, R. H., S. Siemer, S. Becker, G. B. Ding, S. Strieth, and S. K. Knauer. 2018. “Small Meets Smaller: Effects of Nanomaterials on Microbial Biology, Pathology, and Ecology.” ACS Nano 12 (7): 6351–6359. doi:10.1021/acsnano.8b03241.
  • Stauber, R. H., U. Rabenhorst, A. Rekik, K. Engels, C. Bier, and S. K. Knauer. 2006. “Nucleocytoplasmic Shuttling and the Biological Activity of Mouse Survivin Are Regulated by an Active Nuclear Export Signal.” Traffic 7 (11): 1461–1472. doi:10.1111/j.1600-0854.2006.00486.x.
  • Swedin, L., R. Arrighi, B. Andersson-Willman, A. Murray, Y. Chen, M. C. Karlsson, S. K. Georen, et al. 2012. “Pulmonary Exposure to Single-Walled Carbon Nanotubes Does Not Affect the Early Immune Response against Toxoplasma gondii.” Particle and Fibre Toxicology 9 (4): 16. doi:10.1186/1743-8977-9-16.
  • Takazono, T., and D. C. Sheppard. 2017. “Aspergillus in Chronic Lung Disease: Modeling What Goes on in the Airways.” Medical Mycology 55 (1): 39–47. doi:10.1093/mmy/myw117.
  • Tenzer, S., D. Docter, J. Kuharev, A. Musyanovych, V. Fetz, R. Hecht, F. Schlenk, et al. 2013. “Rapid Formation of Plasma Protein Corona Critically Affects Nanoparticle Pathophysiology.” Nature Nanotechnology 8 (10): 772–781. doi:10.1038/nnano.2013.181.
  • Tenzer, S., D. Docter, S. Rosfa, A. Wlodarski, J. Kuharev, A. Rekik, S. K. Knauer, C. Bantz, T. Nawroth, C. Bier, et al. 2011. “Nanoparticle Size is a Critical Physicochemical Determinant of the Human Blood Plasma Corona: A Comprehensive Quantitative Proteomic Analysis.” ACS Nano 5 (9): 7155–7167. doi:10.1021/nn201950e.
  • Teubl, B. J., B. Stojkovic, D. Docter, E. Pritz, G. Leitinger, I. Poberaj, R. Prassl, et al. 2018. “The Effect of Saliva on the Fate of Nanoparticles.” Clinical Oral Investigations 22 (2): 929–940. doi:10.1007/s00784-017-2172-5.
  • Thompson-Coffe, C., G. Borioli, D. Zickler, and A. L. Rosa. 1999. “Pyruvate Decarboxylase Filaments Are Associated with the Cortical Cytoskeleton of Asci and Spores over the Sexual Cycle of Filamentous Ascomycetes.” Fungal Genetics and Biology 26 (1): 71–80. doi:10.1006/fgbi.1998.1106.
  • Tsai, C. J., J. M. Loh, and T. Proft. 2016. “Galleria mellonella Infection Models for the Study of Bacterial Diseases and for Antimicrobial Drug Testing.” Virulence 7 (3): 214–229. doi:10.1080/21505594.2015.1135289.
  • Valsami-Jones, E., and I. Lynch. 2015. “Nanosafety. How Safe Are Nanomaterials?” Science 350 (6259): 388–389. doi:10.1126/science.aad0768.
  • Verweij, P. E., E. Snelders, G. H. Kema, E. Mellado, and W. J. Melchers. 2009. “Azole Resistance in Aspergillus fumigatus: A Side-Effect of Environmental Fungicide Use?” The Lancet. Infectious Diseases 9 (12): 789–795. doi:10.1016/S1473-3099(09)70265-8.
  • Voltan, A. R., G. Quindos, K. P. Alarcon, A. M. Fusco-Almeida, M. J. Mendes-Giannini, and M. Chorilli. 2016. “Fungal Diseases: Could Nanostructured Drug Delivery Systems Be a Novel Paradigm for Therapy?” International Journal of Nanomedicine 11: 3715–3730. doi:10.2147/IJN.S93105.
  • Walkey, C. D., and W. C. Chan. 2012. “Understanding and Controlling the Interaction of Nanomaterials with Proteins in a Physiological Environment.” Chemical Society Reviews 41 (7): 2780–2799. doi:10.1039/c1cs15233e.
  • Walkey, C. D., J. B. Olsen, F. Song, R. Liu, H. Guo, D. W. Olsen, Y. Cohen, A. Emili, and W. C. Chan. 2014. “Protein Corona Fingerprinting Predicts the Cellular Interaction of Gold and Silver Nanoparticles.” ACS Nano 8 (3): 2439–2455. doi:10.1021/nn406018q.
  • Westmeier, D., A. Hahlbrock, C. Reinhardt, J. Frohlich-Nowoisky, S. Wessler, C. Vallet, U. Poschl, S. K. Knauer, and R. H. Stauber. 2018. “Nanomaterial-Microbe Cross-Talk: Physicochemical Principles and (Patho)Biological Consequences.” Chemical Society Reviews 47 (14): 5312–5337. doi:10.1039/c6cs00691d.
  • Westmeier, D., D. Solouk-Saran, C. Vallet, S. Siemer, D. Docter, H. Gotz, L. Mann, et al. 2018. “Nanoparticle Decoration Impacts Airborne Fungal Pathobiology.” Proceedings of the National Academy of Sciences of the United States of America 115 (27): 7087–7092. doi:10.1073/pnas.1804542115.
  • Westmeier, D., G. Posselt, A. Hahlbrock, S. Bartfeld, C. Vallet, C. Abfalter, D. Docter, S. K. Knauer, S. Wessler, and R. H. Stauber. 2018. “Nanoparticle Binding Attenuates the Pathobiology of Gastric Cancer-Associated Helicobacter pylori.” Nanoscale 10 (3): 1453–1463. doi:10.1039/c7nr06573f.
  • Westmeier, D., R. H. Stauber, and D. Docter. 2016. “The Concept of Bio-Corona in Modulating the Toxicity of Engineered Nanomaterials (ENM).” Toxicology and Applied Pharmacology 299: 53–57. doi:10.1016/j.taap.2015.11.008.
  • Wu, J., A. Zawistowski, M. Ehrmann, T. Yi, and C. Schmuck. 2011. “Peptide Functionalized Polydiacetylene Liposomes Act as a Fluorescent Turn-on Sensor for Bacterial Lipopolysaccharide.” Journal of the American Chemical Society 133 (25): 9720–9723. doi:10.1021/ja204013u.
  • Xiao, J., A. Kuc, S. Pokhrel, L. Madler, R. Pottgen, F. Winter, T. Frauenheim, and T. Heine. 2013. “Fe-Doped ZnO Nanoparticles: The Oxidation Number and Local Charge on Iron, Studied by 57Fe Mößbauer Spectroscopy and DFT Calculations.” Chemistry 19 (10): 3287–3291. doi:10.1002/chem.201204308.
  • Yanamala, N., E. R. Kisin, D. W. Gutkin, M. R. Shurin, M. Harper, and A. A. Shvedova. 2018. “Characterization of Pulmonary Responses in Mice to Asbestos/Asbestiform Fibers Using Gene Expression Profiles.” Journal of Toxicology and Environmental Health. Part A 81 (4): 60–79. doi:10.1080/15287394.2017.1408201.
  • Yu, K. P., Y. T. Huang, and S. C. Yang. 2013. “The Antifungal Efficacy of Nano-Metals Supported TiO7₂ and Ozone on the Resistant Aspergillus niger Spore.” Journal of Hazardous Materials 261: 155–162. doi:10.1016/j.jhazmat.2013.07.029.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.