Utilizing literature-based rodent toxicology data to derive potency estimates for quantitative risk assessment

References

• ARA. 2015. Multiple-Path Particle Dosimetry Model (MPPD 3.04). Raleigh, NC: Applied Research Associates, Inc.
   Google Scholar
• ATL. 2015. “Literature Search Protocol: Hazard and Risk Evaluations of Engineered Nanomaterials.” Report submitted to the National Institute for Occupational Safety and Health (NIOSH) by Advanced Technologies and Laboratories under project for Dataset Development for Hazard and Risk Evaluations of Engineered Nanomaterials Based on Toxicology Literature. NIOSH Contract No. Order No. 200-2015-F-62950, September 11.
   Google Scholar
• Barosova, H., B. B. Karakocak, D. Septiadi, A. Petri-Fink, V. Stone, and B. Rothen-Rutishauser. 2020. “An in Vitro Lung System to Assess the Proinflammatory Hazard of Carbon Nanotube Aerosols.” International Journal of Molecular Sciences 21 (15): 5335. doi:10.3390/ijms21155335.
   PubMed Web of Science ®Google Scholar
• Bates, M. E., J. M. Keisler, N. P. Zussblatt, K. J. Plourde, and B. A. Wender. 2016. “Balancing Research and Funding Using Value of Information and Portfolio Tools for Nanomaterial Risk Classification.” Nature Nanotechnology 11: 198–203. doi:10.1038/NNANO.2015.249.
   PubMed Web of Science ®Google Scholar
• Bokkers, B. G., and W. Slob. 2007. “Deriving a Data-Based Interspecies Assessment Factor Using the NOAEL and the Benchmark Dose Approach.” Critical Reviews in Toxicology 37 (5): 355–373. doi:10.1080/10408440701249224.
   PubMed Web of Science ®Google Scholar
• Bonner, J. C., R. M. Silva, A. J. Taylor, J. M. Brown, S. C. Hilderbrand, V. Castranova, D. Porter, et al. 2013. “Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium.” Environmental Health Perspectives 121 (6): 676–682. doi:10.1289/ehp.1205693.
   PubMed Web of Science ®Google Scholar
• Bos, P. M. J., I. Gosens, L. Geraets, C. Delmaar, and F. R. Cassee. 2019. “Pulmonary Toxicity in Rats following Inhalation Exposure to Poorly Soluble Particles: The Issue of Impaired Clearance and the Relevance for Human Health Hazard and Risk Assessment.” Regulatory Toxicology and Pharmacology 109: 104498. doi:10.1016/j.yrtph.2019.104498.
   PubMed Web of Science ®Google Scholar
• Braakuis, H. M., M. V. D. Z. Park, I. Gosens, W. H. De Jong, and F. R. Cassee. 2014. “Physicochemical Characteristics of Nanomaterials That Affect Pulmonary Inflammation.” Particle and Fibre Toxicology 11: 18. doi:10.1186/1743-8977-11-18.
   PubMed Web of Science ®Google Scholar
• Brzicova, T., J. Sikorova, A. Milcova, K. Vrbova, J. Klema, P. Pikal, and P. Rossner. 2019. “Nano-TiO2 Stability in Medium and Size as Important Factors of Toxicity in Macrophage-like Cells.” Toxicology in Vitro 54: 178–188. doi:10.1016/j.tiv.2018.09.019.
   PubMed Web of Science ®Google Scholar
• Crump, K. S. 1984. “A New Method for Determining Allowable Daily Intakes.” Fundamental and Applied Toxicology 4: 854–871. doi:10.1093/toxsci/4.5.854.
   PubMedGoogle Scholar
• Dankovic, D. A., B. D. Naumann, A. Maier, M. L. Dourson, and L. S. Levy. 2015. “The Scientific Basis of Uncertainty Factors Used in Setting Occupational Exposure Limits.” Journal of Occupational and Environmental Hygiene 12 (sup1): S55–S68. doi:10.1080/15459624.2015.1060325.
   PubMed Web of Science ®Google Scholar
• Davis, J. A., J. S. Gift, and Q. J. Zhao. 2011. “Introduction to Benchmark Dose Methods and U.S. EPA’s Benchmark Dose Software (BMDS) Version 2.1.1.” Toxicology and Applied Pharmacology 254 (2): 181–191. doi:10.1016/j.taap.2010.10.016.
   PubMed Web of Science ®Google Scholar
• Donaldson, K., P. J. Borm, G. Oberdörster, K. E. Pinkerton, V. Stone, and C. L. Tran. 2008. “Concordance between in Vitro and in Vivo Dosimetry in the Proinflammatory Effects of Low-Toxicity, Low-Solubility Particles: The Key Role of the Proximal Alveolar Region.” Inhalation Toxicology 20: 53–62. doi:10.1080/08958370701758742.
   PubMed Web of Science ®Google Scholar
• Drew, N. M., E. D. Kuempel, Y. Pei, and F. Yang. 2017. “A Quantitative Framework to Group Nanoscale and Microscale Particles by Hazard Potency to Derive Occupational Exposure Limits: proof of Concept Evaluation.” Regulatory Toxicology and Pharmacology 89: 253–267. doi:https://doi.org/10.1016/j.yrtph.2017.08.003.
   PubMed Web of Science ®Google Scholar
• ECHA. 2017. Read-Across Assessment Framework (RAAF). ECHA-17-R-01-EN. Helsinki, Finland: European Chemicals Agency (ECHA).
   Google Scholar
• Efron, B., and R. Tibshirani. 1986. “Bootstrap Methods for Standard Errors, Confidence Intervals, and Other Measures of Statistical Accuracy.” Statistical Science 1 (1): 54–75. doi:10.1214/ss/1177013815.
   Google Scholar
• EFSA Scientific Community. 2017. “Update: Use of the Benchmark Dose Approach in Risk Assessment.” EFSA Journal 15 (1): 4658. doi:10.2903/j.efsa.2017.4658.
   Web of Science ®Google Scholar
• Fraser, K., V. Kodali, N. Yanamala, M. E. Birch, L. Cena, G. Casuccio, K. Bunker, et al. 2020. “Physicochemical Characterization and Genotoxicity of the Broad Class of Carbon Nanotubes and Nanofibers Used or Produced in U.S. Facilities.” Particle and Fibre Toxicology 17: 62. doi:10.1186/s12989-020-00392-w.
   PubMed Web of Science ®Google Scholar
• Fujita, K., M. Fukuda, S. Endoh, J. Maru, H. Kato, A. Nakamura, and K. Honda. 2015. “Size Effects of Single-Walled Carbon Nanotubes on in Vivo and in Vitro Pulmonary Toxicity.” Inhalation Toxicology 27 (4): 207–223. doi::10.3109/08958378.2015.1026620.
   PubMed Web of Science ®Google Scholar
• Fujita, K., M. Fukuda, S. Endoh, J. Maru, H. Kato, A. Nakamura, and K. Honda. 2016. “Pulmonary and Pleural Inflammation after Intratracheal Instillation of Short Single-Walled and Multi-Walled Carbon Nanotubes.” Toxicology Letters 257: 23–37. doi:10.1016/j.toxlet.2016.05.025.
   PubMed Web of Science ®Google Scholar
• Furxhia, I., F. Murphy, M. Mullins, A. Arvanitis, and C. A. Poland. 2020. “Nanotoxicology Data for in Silico Tools: A Literature Review.” Nanotoxicology 14 (5): 612–637. doi:10.1080/17435390.2020.1729439.
   PubMed Web of Science ®Google Scholar
• Gernand, J. M., and E. A. Casman. 2014. “A Meta-Analysis of Carbon Nanotube Pulmonary Toxicity Studies—How Physical Dimensions and Impurities Affect the Toxicity of Carbon Nanotubes.” Risk Analysis 34 (3): 583–597. doi:10.1111/risa.12109.
   PubMed Web of Science ®Google Scholar
• Halappanavar, S., J. D. Ede, I. Mahapatra, H. F. Krug, E. D. Kuempel, I. Lynch, R. J. Vandebriel, and J. A. Shatkin. 2020. “A Methodology for Developing Key Events to Advance Nanomaterial-Relevant Adverse Outcome Pathways to Inform Risk Assessment.” Nanotoxicology 15 (3): 289–224. doi:10.1080/17435390.2020.1851419.
   PubMed Web of Science ®Google Scholar
• Halappanavar, S., S. van den Brule, P. Nymark, L. Gaté, C. Seidel, S. Valentino, V. Zhernovkov, et al. 2020. “Adverse Outcome Pathways as a Tool for the Design of Testing Strategies to Support the Safety Assessment of Emerging Advanced Materials at the Nanoscale.” Particle and Fibre Toxicology 17 (1): 16. doi:10.1186/s12989-020-00344-4.
   PubMed Web of Science ®Google Scholar
• Hamilton, R. F., Z. Wu, S. Mitra, P. K. Shaw, A. Holian. 2013. “Effect of MWCNT Size, Carboxylation, and Purification on in Vitro and in Vivo Toxicity, Inflammation and Lung Pathology.” Particle and Fibre Toxicology 10 (1): 57. doi:10.1186/1743-8977-10-57.
   PubMedGoogle Scholar
• Hamilton, R. F., Z. Wu, S. Mitra, P. K. Shaw, and A. Holian. 2018. “Length, but Not Reactive Edges, of Cup-Stack MWCNT is Responsible for Toxicity and Acute Lung Inflammation.” Toxicologic Pathology 46 (1): 62–74. doi:10.1177/0192623317732303.
   PubMed Web of Science ®Google Scholar
• ICRP. 2002. Annals of the ICRP (The International Commission on Radiological Protection). In: Basic anatomical and physiological data for use in radiological protection: reference values, edited by Valentin, J. (ICRP Publication 89). Oxford, U.K.: Pergamon.
   Google Scholar
• ICRP. 2015. “Occupational Intakes of Radionuclides: Part 1. The International Commission on Radiological Protection (ICRP) Publication 130.” Annals of the ICRP 44 (2): 59–74.
   Google Scholar
• ISO. 2016. “Nanotechnologies — Overview of Available Frameworks for the Development of Occupational Exposure Limits and Bands for Nano-Objects and Their Aggregates and Agglomerates (NOAAs).” International Organization for Standardization Technical Report. ISO/TR 18637, Geneva, Switzerland: ISO, November 21.
   Google Scholar
• Karlsson, H. L., P. Cronholm, J. Gustafsson, and L. Moller. 2008. “Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes.” Chemical Research in Toxicology 21 (9): 1726–1732. doi:10.1021/tx800064j.
   PubMed Web of Science ®Google Scholar
• Kobayashi, N., M. Naya, S. Endoh, J. Maru, K. Yamamoto, and J. Nakanishi. 2009. “Comparative Pulmonary Toxicity Study of nano-TiO(2) Particles of Different Sizes and Agglomerations in Rats: different Short- and Long-Term Post-Instillation Results.” Toxicology 264 (1–2): 110–118. doi:10.1016/j.tox.2009.08.002.
   PubMed Web of Science ®Google Scholar
• Kuempel, E. D., V. Castranova, C. L. Geraci, and P. A. Schulte. 2012. “Development of Risk-Based Nanomaterial Groups for Occupational Exposure Control.” Journal of Nanoparticle Research 14: 1029. doi:10.1007/s11051-012-1029-8.
   PubMed Web of Science ®Google Scholar
• Lamon, L., D. Asturiol, A. Richarz, E. Joossens, R. Graepel, K. Aschberger, and A. Worth. 2018. “Grouping of Nanomaterials to Read-across Hazard Endpoints: From Data Collection to Assessment of the Grouping Hypothesis by Application of Chemoinformatic Techniques.” Particle and Fibre Toxicology 15: 37. doi:10.1186/s12989-018-0273-1.
   PubMed Web of Science ®Google Scholar
• Lampe, B. J., E. Fuller, and S. P. Kuppusamy. 2018. “A Quantitative Comparison of Points of Departure between 28-Day and 90-Day Repeated Dose Studies with a Proposed Extrapolation Factor.” Regulatory Toxicology and Pharmacology 92: 189–200. doi:10.1016/j.yrtph.2017.12.007.
   PubMed Web of Science ®Google Scholar
• Landsiedel, R., L. Ma-Hock, K. Wiench, W. Wohlleben, and U. G. Sauer. 2017. “Safety Assessment of Nanomaterials Using an Advanced Decision-Making Framework, the DF4nanoGrouping.” Journal of Nanoparticle Research 19 (5): 171. doi:10.1007/s11051-017-3850-6.
   PubMed Web of Science ®Google Scholar
• Lanone, S., F. Rogerieux, J. Geys, A. Dupont, E. Maillot-Marechal, J. Boczkowski, and P. Hoet. 2009. “Comparative Toxicity of 24 Manufactured Nanoparticles in Human Alveolar Epithelial and Macrophage Cell Lines.” Particle and Fibre Toxicology 6: 14. doi:10.1186/1743-8977-6-14.
   PubMed Web of Science ®Google Scholar
• Mercer, R. R., A. F. Hubbs, J. F. Scabilloni, L. Wang, L. A. Battelli, D. Schwegler-Berry, V. Castranova, and D. W. Porter. 2010. “Distribution and Persistence of Pleural Penetrations by Multi-Walled Carbon Nanotubes.” Particle and Fibre Toxicology 7: 28. doi:10.1186/1743-8977-7-28.
   PubMed Web of Science ®Google Scholar
• Mihalache, R., J. Verbeek, H. Graczyk, V. Murashov, and P. van Broekhuizen. 2017. “Occupational Exposure Limits for Manufactured Nanomaterials, A Systematic Review.” Nanotoxicology 11 (1): 7–13. doi:10.1080/17435390.2016.1262920.
   PubMed Web of Science ®Google Scholar
• NAS. 1983. Risk Assessment in the Federal Government: Managing the Process. Committee on the Institutional Means for Assessment of Risks to Public Health, Commission on Life Sciences, National Research Council, National Academy of Sciences. Washington, DC: National Academies Press.
   Google Scholar
• NAS. 2007. Toxicity Testing in the 21st Century: A Vision and a Strategy. Washington, DC: National Academy of Sciences, National Academies Press.
   Google Scholar
• NAS. 2009. Science and Decisions: Advancing Risk Assessment. Committee on Improving Risk Analysis Approaches Used by the U.S. EPA, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council, National Academy of Sciences. Washington, DC: National Academies Press.
   Google Scholar
• NAS. 2017. Using 21st Century Science to Improve Risk-Related Evaluation. Washington, DC: National Academy of Sciences, National Academies Press.
   Google Scholar
• Nel, A. E., E. Nasser, H. Godwin, D. Avery, T. Bahadori, L. Bergeson, E. Beryt, et al. 2013. “A Multi-Stakeholder Perspective on the Use of Alternative Test Strategies for Nanomaterial Safety Assessment.” ACS Nano. 7 (8): 6422–6433. doi:10.1021/nn4037927.
   PubMed Web of Science ®Google Scholar
• NIOSH. 2011. Current Intelligence Bulletin 63: Occupational Exposure to Titanium Dioxide. Cincinnati, OH: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health (DHHS (NIOSH) Publication No. 2011-160).
   Google Scholar
• NIOSH. 2013. Current Intelligence Bulletin 65: Occupational Exposure to Carbon Nanotubes and Nanofibers. Cincinnati, OH: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health (DHHS (NIOSH) Publication No. 2013-14).
   Google Scholar
• NIOSH. 2019. Technical Report: The NIOSH occupational exposure banding process for chemical risk management. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health (DHHS (NIOSH) Publication No. 2019-132, NIOSH).
   Google Scholar
• NIOSH. 2020. Current Intelligence Bulletin 69: NIOSH Practices in Occupational Risk Assessment. Cincinnati, OH: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health (DHHS (NIOSH) Publication No. 2020-106 (revised 03/2020).
   Google Scholar
• Oberdörster, G., A. Maynard, K. Donaldson, V. Castranova, J. Fitzpatrick, K. Ausman, J. Carter, et al. 2005. “Principles for Characterizing the Potential Human Health Effects from Exposure to Nanomaterials: elements of a Screening Strategy.” Particle and Fibre Toxicology 2 (1): 8–35. doi:10.1186/1743-8977-2-8.
   PubMed Web of Science ®Google Scholar
• OECD. 2014a. “OECD Series on the Safety of Manufactured Nanomaterials, No. 41.” Report of the OECD expert meeting on the physico-chemical properties of manufactured nanomaterials and test guidelines, OECD, Paris, France, pp. 56, ENV/JM/MONO (2014)15.
   Google Scholar
• OECD. 2014b. Guidance on Grouping of Chemicals. 2nd ed. (Series on Testing and Assessment, no. 194, ENV/JM/MONO(2014)4). Paris, France: Organization for Economic Cooperation and Development, Environmental Health and Safety Publications.
   Google Scholar
• OECD. 2016. Alternative Testing Strategies in Risk Assessment of Manufactured Nanomaterials: Current State of Knowledge and Research Needs to Advance their Use (Series on the Safety of Manufactured Nanomaterials, no. 80, ENV/JM/MONO(2016)63). Paris, France: Organization for Economic Cooperation and Development, Environmental Health and Safety Publications.
   Google Scholar
• Piccinno, F., F. Gottschalk, S. Seeger, and B. Nowack. 2012. “Industrial Production Quantities and Uses of Ten Engineered Nanomaterials in Europe and the World.” Journal of Nanoparticle Research 14 (9): 1109. doi:10.1007/s11051-012-1109-9.
   Web of Science ®Google Scholar
• R Core Team. 2019. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing.
   Google Scholar
• Ramchandran, V., and J. M. Gernand. 2019. “A Dose-Response-Recovery Clustering Algorithm for Categorizing Carbon Nanotube Variants into Toxicologically Distinct Groups.” Computational Toxicology 11: 25–32. doi:10.1016/j.comtox.2019.02.003.
   Google Scholar
• Ramchandran, V., and J. M. Gernand. 2020. “Examining the in Vivo Pulmonary Toxicity of Engineered Metal Oxide Nanomaterials Using a Genetic Algorithm-Based Dose-Response-Recovery Clustering Method.” Computational Toxicology 13: 100113. doi:10.1016/j.comtox.2019.100113.
   Google Scholar
• Rao, G. V., S. Tinkle, D. N. Weissman, J. M. Antonini, M. L. Kashon, R. Salmen, L. A. Battelli, P. A. Willard, M. D. Hoover, and A. F. Hubbs. 2003. “Efficacy of a Technique for Exposing the Mouse Lung to Particles Aspirated from the Pharynx.” Journal of Toxicology and Environmental Health Part A 66 (15): 1441–1452. doi:10.1080/15287390306417.
   PubMed Web of Science ®Google Scholar
• Rasmussen, K., H. Rauscher, A. Mech, J. Riego Sintes, D. Gilliland, M. González, P. Kearns, et al. 2018. “Physico-Chemical Properties of Manufactured nanomaterials - Characterisation and Relevant Methods. An Outlook Based on the OECD Testing Programme.” Regulatory Toxicology Pharmacology 92: 8–28. doi:10.1016/j.yrtph.2017.10.019.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Ibarra, C., A. Deciga-Alcaraz, O. Ispanixtlahuatl-Meraz, E. I. Medina-Reyes, N. L. Delgado-Buenrostro, and Y. I. Chirino. 2020. “International Landscape of Limits and Recommendations for Occupational Exposure to Engineered Nanomaterials.” Toxicology Letters 322: 111–119. doi:10.1016/j.toxlet.2020.01.016.
   PubMed Web of Science ®Google Scholar
• Rushton, E. K., J. Jiang, S. S. Leonard, S. Eberly, V. Castranova, P. Biswas, A. Elder, et al. 2010. “Concept of Assessing Nanoparticle Hazards considering Nanoparticle Dosemetric and Chemical/Biological Response Metrics.” Journal of Toxicology and Environmental Health Part A 73 (5): 445–461. doi:10.1080/15287390903489422.
   PubMed Web of Science ®Google Scholar
• Sager, T. M., C. Kommineni, and V. Castranova. 2008. “Pulmonary Response to Intratracheal Instillation of Ultrafine versus Fine Titanium Dioxide: role of Particle Surface Area.” Particle and Fibre Toxicology 5: 17. doi:10.1186/1743-8977-5-17.
   PubMed Web of Science ®Google Scholar
• Schulte, P. A., V. Leso, M. Niang, et al. 2019. “Current State of Knowledge on the Health Effects of Engineered Nanomaterials in Workers: A Systematic Review of Human Studies and Epidemiological Investigations.” Scandinavian Journal of Work, Environment and Health 45 (3): 217–238. doi:10.5271/sjweh.3800.
   PubMed Web of Science ®Google Scholar
• Sheehan, B., F. Murphy, M. Mullins, I. Furxhi, A. Costa, F. Simeone, and P. Mantecca. 2018. “Hazard Screening Methods for Nanomaterials: A Comparative Study.” International Journal of Molecular Sciences 19 (3): 649. Available from: 10.3390/ijms19030649.
   PubMed Web of Science ®Google Scholar
• Stoehr, L. C., E. Gonzalez, A. Stampfl, E. Casals, A. Duschl, V. Puntes, and G. J. Oostingh. 2011. “Shape Matters: effects of Silver Nanospheres and Wires on Human Alveolar Epithelial Cells.” Particle and Fibre Toxicology 8 (1): 36. doi:10.1186/1743-8977-8-36.
   PubMedGoogle Scholar
• Stueckle, T. A., D. C. Davidson, R. Derk, P. Wang, S. Friend, D. Schwegler-Berry, and L. Wang. 2017. “Effect of Surface Functionalizations of Multi-Walled Carbon Nanotubes on Neoplastic Transformation Potential in Primary Human Lung Epithelial Cells.” Nanotoxicology 11 (5): 613–624. doi:10.1080/17435390.2017.1332253.
   PubMed Web of Science ®Google Scholar
• U.S. EPA. 2012. Benchmark Dose Technical Guidance (EPA/100/R-12/001). Washington, DC: U.S. Environmental Protection Agency.
   Google Scholar
• U.S. EPA. 2014. Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology (EPA/600/R-14/004). Washington, DC: U.S. Environmental Protection Agency, National Center for Environmental Assessment, Office of Research and Development.
   Google Scholar
• U.S. EPA. 1994. Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry (EPA/600/8-9Q/066f). Washington, DC: U.S. Environmental Protection Agency.
   Google Scholar
• Valavanidis, A. V., and T. Vlachogianni. 2016. “Engineered Nanomaterials for Pharmaceutical and Biomedical Products New Trends, Benefits and Opportunities.” Pharmaceutical Bioprocessing 4 (1): 013–024.
   Google Scholar
• WHO. 2017. Guidelines on Protecting Workers from Potential Risks of Manufactured Nanomaterials. Geneva: World Health Organization.
   Google Scholar
• Xia, T., R. F. Hamilton, J. C. Bonner, E. D. Crandall, A. Elder, F. Fazlollahi, T. A. Girtsman, et al. 2013. “Interlaboratory Evaluation of in Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium.” Environmental Health Perspectives 121 (6): 683–690. doi:10.1289/ehp.1306561.
   PubMed Web of Science ®Google Scholar
• Yu, Q., H. Wang, Q. Peng, Y. Li, Z. Liu, and M. Li. 2017. “Different Toxicity of Anatase and Rutile TiO2 Nanoparticles on Macrophages: Involvement of Difference in Affinity to Proteins and Phospholipids.” Journal of Hazardous Materials 335: 125–134. doi:10.1016/j.jhazmat.2017.04.026.
   PubMed Web of Science ®Google Scholar
• Zhang, H., Z. Ji, T. Xia, H. Meng, C. Low-Kam, R. Liu, S. Pokhrel, et al. 2012. “Use of Metal Oxide Nanoparticle Band Gap to Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation.” ACS NA 6 (5): 4349–4368. doi:10.1021/nn3010087.
   PubMed Web of Science ®Google Scholar
• Zhang, T., T. Meng, L. Kong, H. Li, T. Zhang, Y. Xue, and Y. Pu. 2015. “Surface Modification of Multiwall Carbon Nanotubes Determines the Pro-Inflammatory Outcome in Macrophage.” Journal of Hazardous Materials 284: 73–82. doi:10.1016/j.jhazmat.2014.11.013.
   PubMed Web of Science ®Google Scholar