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Articles

Engineered aluminum nanoparticle induces mitochondrial deformation and is predicated on cell phenotype

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Pages 1215-1232 | Received 28 Apr 2021, Accepted 23 Nov 2021, Published online: 25 Jan 2022

References

  • Berg, J. M., S. Ho, W. Hwang, R. Zebda, K. Cummins, M. P. Soriaga, R. Taylor, B. Guo, and C. M. Sayes. 2010. “Internalization of Carbon Black and Maghemite Iron Oxide Nanoparticle Mixtures Leads to Oxidant Production.” Chemical Research in Toxicology 23 (12): 1874–1882.
  • Brar, S. K., M. Verma, R. D. Tyagi, and R. Y. Surampalli. 2010. “Engineered Nanoparticles in Wastewater and Wastewater Sludge–Evidence and Impacts.” Waste Management 30 (3): 504–520.
  • Brevini, T. A. L., R. Vassena, C. Francisci, and F. Gandolfi. 2005. “Role of Adenosine Triphosphate, Active Mitochondria, and Microtubules in the Acquisition of Developmental Competence of Parthenogenetically Activated Pig Oocytes.” Biology of Reproduction 72 (5): 1218–1223.
  • Chan, D. C. 2012. “Fusion and Fission: interlinked Processes Critical for Mitochondrial Health.” Annual Review of Genetics 46: 265–287.
  • Chattopadhyay, M., V. K. Khemka, G. Chatterjee, A. Ganguly, S. Mukhopadhyay, and S. Chakrabarti. 2015. “Enhanced ROS Production and Oxidative Damage in Subcutaneous White Adipose Tissue Mitochondria in Obese and Type 2 Diabetes Subjects.” Molecular and Cellular Biochemistry 399 (1–2): 95–103.
  • Cloonan, S. M., and A. M. Choi. 2016. “Mitochondria in Lung Disease.” The Journal of Clinical Investigation 126 (3): 809–820. doi:https://doi.org/10.1172/JCI81113.
  • Cogliati, S., J. A. Enriquez, and L. Scorrano. 2016. “Mitochondrial Cristae: where Beauty Meets Functionality.” Trends in Biochemical Sciences 41 (3): 261–273.
  • Darlington, T. K., A. M. Neigh, M. T. Spencer, O. T. N. Guyen, and S. J. Oldenburg. 2009. “Nanoparticle Characteristics Affecting Environmental Fate and Transport through Soil.” Environmental Toxicology and Chemistry 28 (6): 1191–1199. doi:https://doi.org/10.1897/08-341.1.
  • Davda, J., and V. Labhasetwar. 2002. “Characterization of Nanoparticle Uptake by Endothelial Cells.” International Journal of Pharmaceutics 233 (1–2): 51–59.
  • Delp, J., A. Cediel-Ulloa, I. Suciu, P. Kranaster, B. M. van Vugt-Lussenburg, V. Munic Kos, W. van der Stel, et al. 2021. “Neurotoxicity and Underlying Cellular Changes of 21 Mitochondrial Respiratory Chain Inhibitors.” Archives of Toxicology 95 (2): 591–615.
  • Dreier, D. A., D. F. Mello, J. N. Meyer, and C. J. Martyniuk. 2019. “Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: progress and Considerations for Mitochondrial Adverse Outcome Pathways.” Environmental Toxicology and Chemistry 38 (8): 1625–1634.
  • Esch, E. W., A. Bahinski, and D. Huh. 2015. “Organs-on-Chips at the Frontiers of Drug Discovery.” Nature Reviews Drug Discovery 14 (4): 248–260. doi:https://doi.org/10.1038/nrd4539.
  • Ghribi, O., D. A. Dewitt, M. S. Forbes, M. M. Herman, and J. Savory. 2001. “Co-Involvement of Mitochondria and Endoplasmic Reticulum in Regulation of Apoptosis: changes in Cytochrome c, Bcl-2 and Bax in the Hippocampus of Aluminum-Treated Rabbits.” Brain Research 903 (1–2): 66–73. doi:https://doi.org/10.1016/S0006-8993(01)02406-4.
  • Huang, S., L. Wiszniewski, J. P. Derouette, and S. Constant. 2009. “In Vitro Organ Culture Models of Asthma.” Drug Discovery Today: Disease Models 6: 137–144.
  • Jheng, H. F., P. J. Tsai, S. M. Guo, L. H. Kuo, C. S. Chang, I. J. Su, C. R. Chang, and Y. S. Tsai. 2012. “Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle.” Molecular and Cellular Biology 32 (2): 309–319.
  • Jiang, R. D., H. Shen, and Y. J. Piao. 2010. “The Morphometrical Analysis on the Ultrastructure of A549 Cells.” Revue Roumaine de Morphologie et Embryologie [Romanian Journal of Morphology and Embryology] 51 (4): 663–667.
  • Jin, C., and P. Yuan. 2020. “Implications of Lipid Droplets in Lung Cancer: Associations with Drug Resistance.” Oncology Letters 20 (3): 2091–2104.
  • Karbowski, M., and R. J. Youle. 2003. “Dynamics of Mitochondrial Morphology in Healthy Cells and during Apoptosis.” Cell Death and Differentiation 10 (8): 870–880. doi:https://doi.org/10.1038/sj.cdd.4401260.
  • Kim, H. J., D. H. Jung, I. H. Jung, J. I. Cifuentes, K. Y. Rhee, and D. Hui. 2012. “Enhancement of Mechanical Properties of Aluminium/Epoxy Composites with Silane Functionalization of Aluminium Powder.” Composites Part B: Engineering 43 (4): 1743–1748. doi:https://doi.org/10.1016/j.compositesb.2011.12.010.
  • Kirkpatrick, C. J., and C. Mittermayer. 1990. “Theoretical and Practical Aspects of Testing Potential Biomaterials in Vitro.” Journal of Materials Science 1: 9–13.
  • Kowaltowski, A. J., and A. E. Vercesi. 1999. “Mitochondrial Damage Induced by Conditions of Oxidative Stress.” Free Radical Biology & Medicine 26 (3–4): 463–471. doi:https://doi.org/10.1016/s0891-5849(98)00216-0.
  • Li, R., X. Kou, H. Geng, J. Xie, J. Tian, Z. Cai, and C. Dong. 2015. “Mitochondrial Damage: An Important Mechanism of Ambient PM2. 5 Exposure-Induced Acute Heart Injury in Rats.” Journal of Hazardous Materials 287: 392–401.
  • Lujan, H., M. F. Criscitiello, A. S. Hering, and C. M. Sayes. 2019. “Refining in Vitro Toxicity Models: Comparing Baseline Characteristics of Lung Cell Types.” Toxicological Sciences 168 (2): 302–314.
  • Lujan, H., and C. M. Sayes. 2017. “Cytotoxicological Pathways Induced after Nanoparticle Exposure: Studies of Oxidative Stress at the 'Nano-Bio' Interface.” Toxicology Research 6 (5): 580–594. doi:https://doi.org/10.1039/c7tx00119c.
  • Mabalirajan, U., and B. Ghosh. 2013. “Mitochondrial Dysfunction in Metabolic Syndrome and Asthma.” Journal of Allergy 2013: 340476.
  • Mcminn, B., A. L. Duval, and C. M. Sayes. 2019. “An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease.” Journal of Toxicology 2019: 9246495.
  • Mirshafa, A., M. Nazari, D. Jahani, and F. Shaki. 2018. “Size-Dependent Neurotoxicity of Aluminum Oxide Particles: A Comparison between Nano-and Micrometer Size on the Basis of Mitochondrial Oxidative Damage.” Biological Trace Element Research 183 (2): 261–269.
  • Mortimer, M., A. Gogos, N. Bartolomé, A. Kahru, T. D. Bucheli, and V. I. Slaveykova. 2014. “Potential of Hyperspectral Imaging Microscopy for Semi-Quantitative Analysis of Nanoparticle Uptake by Protozoa.” Environmental Science & Technology 48 (15): 8760–8767. doi:https://doi.org/10.1021/es500898j.
  • Mulenos, M. R., H. Lujan, L. R. Pitts, and C. M. Sayes. 2020. “Silver Nanoparticles Agglomerate Intracellularly Depending on the Stabilizing Agent: Implications for Nanomedicine Efficacy.” Nanomaterials 10 (10): 1953. doi:https://doi.org/10.3390/nano10101953.
  • Murakami, K., and M. Yoshino. 2004. “Aluminum Decreases the Glutathione Regeneration by the Inhibition of NADP‐Isocitrate Dehydrogenase in Mitochondria.” Journal of Cellular Biochemistry 93 (6): 1267–1271.
  • Murphy, D. J., and J. Vance. 1999. “Mechanisms of Lipid-Body Formation.” Trends in Biochemical Sciences 24 (3): 109–115.
  • Niu, P. Y., Q. Niu, Q. L. Zhang, L. P. Wang, S. C. He, T. C. Wu, P. Conti, M. DI Gioacchino, and P. Boscolo. 2005. “Aluminum Impairs Rat Neural Cell Mitochondria in Vitro.” International Journal of Immunopathology and Pharmacology 18 (4): 683–689.
  • Panariti, A., G. Miserocchi, and I. Rivolta. 2012. “The Effect of Nanoparticle Uptake on Cellular Behavior: Disrupting or Enabling Functions?” Nanotechnology, Science and Applications 5: 87–100. doi:https://doi.org/10.2147/NSA.S25515.
  • Patiño, T., J. Soriano, L. Barrios, E. Ibáñez, and C. Nogués. 2015. “Surface Modification of Microparticles Causes Differential Uptake Responses in Normal and Tumoral Human Breast Epithelial Cells.” Scientific Reports 5: 11371.
  • Puleston, D. 2015. “Detection of Mitochondrial Mass, Damage, and Reactive Oxygen Species by Flow Cytometry.” Cold Spring Harbor Protocols 2015 (9): pdb.prot086298. doi:https://doi.org/10.1101/pdb.prot086298.
  • Rampelt, H., R. M. Zerbes, M. VAN DER Laan, and N. Pfanner. 2017. “Role of the Mitochondrial Contact Site and Cristae Organizing System in Membrane Architecture and Dynamics.” Biochimica et Biophysica Acta [Molecular Cell Research] 1864 (4): 737–746. doi:https://doi.org/10.1016/j.bbamcr.2016.05.020.
  • Sastre, J., F. V. Pallardó, D. E L. A. García, J. Asunción, and J. Viña. 2000. “Mitochondria, Oxidative Stress and Aging.” Free Radical Research 32 (3): 189–198. doi:https://doi.org/10.1080/10715760000300201.
  • Sayes, C. M., K. L. Reed, S. Subramoney, L. Abrams, and D. B. Warheit. 2009. “Can in Vitro Assays Substitute for in Vivo Studies in Assessing the Pulmonary Hazards of Fine and Nanoscale Materials?” Journal of Nanoparticle Research 11 (2): 421–431. doi:https://doi.org/10.1007/s11051-008-9471-3.
  • Schousboe, A., H. M. Sickmann, L. K. Bak, I. Schousboe, F. S. Jajo, S. A. A. Faek, and H. S. Waagepetersen. 2011. “Neuron–Glia Interactions in Glutamatergic Neurotransmission: roles of Oxidative and Glycolytic Adenosine Triphosphate as Energy Source.” Journal of Neuroscience Research 89 (12): 1926–1934.
  • Shannahan, J. H., X. Lai, P. C. Ke, R. Podila, J. M. Brown, and F. A. Witzmann. 2013. “Silver Nanoparticle Protein Corona Composition in Cell Culture Media.” PLoS One 8 (9): e74001.
  • Shintani, T., and D. J. Klionsky. 2004. “Autophagy in Health and Disease: A Double-Edged Sword.” Science 306 (5698): 990–995.
  • Song, Y., and D. L. Villeneuve. 2021. “AOP Report: Uncoupling of Oxidative Phosphorylation Leading to Growth Inhibition via Decreased Cell Proliferation.” Environmental Toxicology and Chemistry 40 (11): 2959–2967. doi:https://doi.org/10.1002/etc.5197.
  • Stern, S. T., P. P. Adiseshaiah, and R. M. Crist. 2012. “Autophagy and Lysosomal Dysfunction as Emerging Mechanisms of Nanomaterial Toxicity.” Particle and Fibre Toxicology 9: 20.
  • Terron, A., A. Bal-Price, A. Paini, F. Monnet-Tschudi, S. H. Bennekou, M. Leist, S. Schildknecht, and E. W. E. Members, EFSA WG EPI1 Members. 2018. “An Adverse Outcome Pathway for Parkinsonian Motor Deficits Associated with Mitochondrial Complex I Inhibition.” Archives of Toxicology 92 (1): 41–82.
  • Twig, G., and O. S. Shirihai. 2011. “The Interplay Between Mitochondrial Dynamics and Mitophagy.” Antioxidants & Redox Signaling 14 (10): 1939–1951. doi:https://doi.org/10.1089/ars.2010.3779.
  • Warheit, D. B., R. A. Hoke, C. Finlay, E. M. Donner, K. L. Reed, and C. M. Sayes. 2007. “Development of a Base Set of Toxicity Tests Using Ultrafine TiO2 Particles as a Component of Nanoparticle Risk Management.” Toxicology Letters 171 (3): 99–110.
  • Wei, Y., J. J. Zhang, Z. Li, A. Gow, K. F. Chung, M. Hu, Z. Sun, L. Zeng, et al. 2016. “Chronic Exposure to Air Pollution Particles Increases the Risk of Obesity and Metabolic Syndrome: Findings from a Natural Experiment in Beijing.” FASEB Journal 30 (6): 2115–2122. doi:https://doi.org/10.1096/fj.201500142.
  • Wu, S., F. Zhou, Z. Zhang, and D. Xing. 2011. “Mitochondrial Oxidative Stress Causes Mitochondrial Fragmentation via Differential Modulation of Mitochondrial Fission–Fusion Proteins.” The FEBS Journal 278 (6): 941–954.
  • Youle, R. J., and D. P. Narendra. 2011. “Mechanisms of Mitophagy.” Nature Reviews. Molecular Cell Biology 12 (1): 9–14.
  • Yu, T., J. L. Robotham, and Y. Yoon. 2006. “Increased Production of Reactive Oxygen Species in Hyperglycemic Conditions Requires Dynamic Change of Mitochondrial Morphology.” Proceedings of the National Academy of Sciences 103 (8): 2653–2658. doi:https://doi.org/10.1073/pnas.0511154103.
  • Yu, T., L. Wang, and Y. Yoon. 2015. “Morphological Control of Mitochondrial Bioenergetics.” Frontiers in Bioscience (Landmark Edition) 20: 229.
  • Zhang, L., W. Wang, B. Zhu, and X. Wang. 2017. "Epithelial Mitochondrial Dysfunction in Lung Disease." In Mitochondrial DNA and Diseases. Advances in Experimental Medicine and Biology, edited by H. Sun and X. Wang, vol 1038.  Singapore: Springer. doi:https://doi.org/10.1007/978-981-10-6674-0_14
  • Zhang, Y., C. Yu, G. Huang, C. Wang, and L. Wen. 2010. “Nano Rare-Earth Oxides Induced Size-Dependent Vacuolization: An Independent Pathway from Autophagy.” International Journal of Nanomedicine 5: 601–609.
  • Zick, M., R. Rabl, and A. S. Reichert. 2009. “Cristae Formation—Linking Ultrastructure and Function of Mitochondria.” Biochimica et Biophysica Acta [Molecular Cell Research] 1793 (1): 5–19. doi:https://doi.org/10.1016/j.bbamcr.2008.06.013.
  • Zucker, R. M., J. Ortenzio, L. L. Degn, J. M. Lerner, and W. K. Boyes. 2019. “Biophysical Comparison of Four Silver Nanoparticles Coatings Using Microscopy, Hyperspectral Imaging and Flow Cytometry.” PLOS One 14 (7): e0219078.
  • Zyuzin, M. V., T. Honold, S. Carregal‐Romero, K. Kantner, M. Karg, and W. J. Parak. 2016. “Influence of Temperature on the Colloidal Stability of Polymer‐Coated Gold Nanoparticles in Cell Culture Media.” Small 12 (13): 1723–1731.