Toxicological investigation of surface engineered fifth generation poly (propyleneimine) dendrimers in vivo

References

• Agashe HB, Babbar AK, Jain S, Sharma RK, Mishra AK, Asthna A, Garg M, Dutta T, Jain NK. Investigation on biodistribution of technetium 99m labled carbohydrate coated Poly(propyleneimine) dendrimers. Nanomedicine 2007; 3: 120–127
   PubMed Web of Science ®Google Scholar
• Agashe HB, Dutta T, Garg M, Jain NK. Investigations on toxicological profile of functionalized fifth generation poly(propylene imine) dendrimer. J Pharm Pharmacol 2006; 58(11)1491–1498
   PubMed Web of Science ®Google Scholar
• Ambade A, Sarariar E, Thayumanavam S. Dendrimeric michelles for controlled drug release and targeted drug delivery. Mol Pharmaceut 2005; 2(4)264–272
   PubMed Web of Science ®Google Scholar
• Aulenta F, Hayes W, Rannard S. Dendrimers: A new class of nanoscopic containers and delivery devices. Eur Polym J 2003; 39: 1741–1771
   Web of Science ®Google Scholar
• Berg JM, Tymoczko JK, Stryer L. 2005. Isozymes provide a means of regulation specific to distinct tissues and developmental stages: In Biochemistry. 5th ed. New York: W.H. Freeman and Co. pp 421–433.
   Google Scholar
• Bhadra D, Bhadra S, Jain NK. PEGylated peptide-based dendritic nanoparticulate systems for delivery of artimether. J Drug Del Sci Tech 2005; 15(1)65–73
   Web of Science ®Google Scholar
• Bhadra D, Bhadra S, Jain S, Jain NK. A PEGyalted dendritic nanoparticulate carrier of 5-fluorouracil. Int J Pharm 2003; 257: 111–124
   PubMed Web of Science ®Google Scholar
• Boas U, Heegaard PMH. Dendrimers in drug research. Chem Soc Rev 2004; 33: 43–63
   PubMed Web of Science ®Google Scholar
• Chenoweth MB, Hake CL. The smaller halogenated aliphatic hydrocarbons. Am Rev Pharmacol 1962; 2: 363–398
   Google Scholar
• Duncan R, Izzo L. Dendrimer biocompatibility and toxicity. Adv Drug Del Rev 2005; 57: 2215–2237
   PubMed Web of Science ®Google Scholar
• Dutta T, Agashe HB, Garg M, Balakrishnan P, Kabra M, Jain NK. Poly(propyleneimine) dendrimer based nanocontainers for targeting of efavirenz to human monocytes/macrophages in vitro. J Drug Target 2007; 15(1)89–98
   PubMed Web of Science ®Google Scholar
• Dutta T, Agashe HB, Vijayarajkumar P, Joshi M, Jain NK. Dendrosome based gene delivery. J Exp Nanosci 2006; 1(2)235–248
   Web of Science ®Google Scholar
• Dutta T, Jain NK. Targeting potential and anti HIV activity of lamivudine loaded mannosylated poly(propyleneimine) dendrimer. Biochim Biophys Acta 2007; 1770: 681–186
   PubMed Web of Science ®Google Scholar
• Fridkin M, Najjar VA. Tuftsin: Its chemistry, biology, and clinical potential. Crit Rev Biochem Mol Biol 1989; 24: 1–40
   PubMed Web of Science ®Google Scholar
• Khandare J, Kohle P, Pillai O, Kannan S, Lieh-Lai M, Kannan R. Synthesis, cellular transport and activity of polyamidoamine dendrimer-methylpridnisolone conjugates. Bioconj Chem 2005; 16: 330–337
   PubMed Web of Science ®Google Scholar
• Kihara F, Arima H, Tsutsumi T, Hirayama F, Uekama K. In vitro and in vivo gene transfer by optimised a-cyclodextrin conjugate with polyamido amine dendrimer. Bioconj Chem 2003; 14: 342–350
   PubMed Web of Science ®Google Scholar
• Kojima C, Kono K, Maruyama K, Takagishi T. Synthesis of polyamidoamine dendrimers having poly(ethylene) glycol grafts and their ability to encapsulate anti-cancer drugs. Bioconj Chem 2000; 11: 910–917
   PubMed Web of Science ®Google Scholar
• Lapatsanis L, Milias G, Froussios K, Kolovos M. 1983. Synthesis of N-2,2,2- (tricholoroethoxycarbonyl)-1-amino acids and N-(9-fluorenylmethoxycarbonyl)-1-amino acids involving succinimidoxy anion as a leaving group in amino acid protection. Synthesis 8:671–673.
   Google Scholar
• Liu M, Kono K, Frechet JMJ. Water-soluble dendritic unimolecular micelles: Teir potential as drug delivery agents. J Control Release 2000; 65: 121–131
   PubMed Web of Science ®Google Scholar
• Liu MJ, Frechet JMJ. Designing dendrimers for drug delivery. Pharm Sci Technol Today 1999; 2: 393–401
   PubMedGoogle Scholar
• Malik N, Wiwattanapatapee R, Klopsch R, Lorenz K, Frey H, Weener JW, Meijer EW, Paulus W, Dunkan R. Dendrimers: Relationship between structure and biocompatibility in vitro and preliminary studies on the biodistribution of 125I labeled polyamodoamine dendrimers in vivo. J Control Release 2000; 65: 133–148
   PubMed Web of Science ®Google Scholar
• Mitra SK, Venkataranganna MV, Sundaram R, Gopumadhavan S. Protective effect of HD-03, a herbal formulation, against various hepatotoxic agents in rats. J Ethanopharmacol 1998; 63: 181–186
   PubMed Web of Science ®Google Scholar
• Najjar VA. Biological effects of tuftsin and its analogs. Drug Future 1987; 12: 147–160
   Google Scholar
• Quintana A, Raczka E, Piehler L, Lee I, Mye A, Majoros I, Patri A, Thomas T, Mule J, Baker JR., Jr. Design and function of dendrimer based therapeutic nanodevice targeted to tumour cells through folate receptors. Pharm Res 2002; 19(9)1310–1316
   PubMed Web of Science ®Google Scholar
• Roberts J, Balghat M, Zera R. Preliminary biological evaluations of polyamidoamine (PAMAM) StarburstTM dendrimers. J Biomed Res 1996; 30: 53–65
   PubMed Web of Science ®Google Scholar
• Shakthivel T, Florence AT. Dendrimers and dendrons: Facets of pharmaceutical nanotechnology. Drug Delivery Technol 2003; 3: 73–78
   Google Scholar
• Sideratou Z, Tsiourvas D, Paleos CM. Quaternized Poly(propyleneimine) dendrimers as novel pH-sensitive controlled release system. Langmuir 2000; 16: 1766–1769
   Web of Science ®Google Scholar
• Stiriba SE, Frey H, Haag R. Dendritic polymers in biomedical applications: From potential to clinical use in diagnostics and therapy. Angew Chem Int Ed 2002; 41: 1329–1334
   PubMed Web of Science ®Google Scholar
• Tomalia DA. Birth of a New Macromolecular Architecture: Dendrimers as quantized building blocks for nanoscale synthetic organic chemistry. Aldrichimica ACTA 2004; 37(2)39–57
   Web of Science ®Google Scholar
• Wilbur D, Pathare P, Hamlin D, Bhular K, Vessela R. Biotin reagents for antibody pretargeting. 3. Synthesis, radioiodination, and evaluation of biotinylated starburst dendrimers. Bioconj Chem 1998; 9: 813–825
   PubMed Web of Science ®Google Scholar
• Zinselmeyer B, Mackay S, Schatzlein A, Uchegbu I. The lower-generation polypropyleneimine dendrimers are effective gene transfer agents. Pharm Res 2002; 19(7)960–967
   PubMed Web of Science ®Google Scholar