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Global Public Health
An International Journal for Research, Policy and Practice
Volume 9, 2014 - Issue 7
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Original Articles

The syndemics of childhood diarrhoea: A biosocial perspective on efforts to combat global inequities in diarrhoea-related morbidity and mortality

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Pages 841-853 | Received 28 Jan 2014, Accepted 21 Mar 2014, Published online: 08 Jul 2014

References

  • Albert, M. J., Bhat, P., Rajan, D., Maiya, P. P., Pereira, S. M., & Baker, S. J. (1978). Faecal flora of South Indian infants and young children in health and with acute gastroenteritis. Journal of Medical Microbiology, 11(2), 137–143. doi:10.1099/00222615-11-2-137
  • Al-Hasan, M. N., McCormick, M., & Ribes, J. A. (2007). Invasive enteric infections in hospitalized patients with underlying strongyloidiasis. American Journal of Clinical Pathology, 128, 622–627. doi:10.1309/pk0rdqwb764c3wq2
  • Avachat, S. S., Phalke, V. D., Phalke, D. B., Aarif, S. M., & Kalakoti, P. (2011). A cross-sectional study of socio-demographic determinants of recurrent diarrhoea among children under five of rural area of Western Maharashtra, India. The Australasian Medical Journal, 4(2), 72–75. doi:10.4066/amj.2011.524
  • Bailey, M. T., & Coe, C. L. (1999). Maternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys. Developmental Psychobiology, 35, 146–155. doi:10.1002/(SICI)1098-2302(199909)35:2%3C146::AID-DEV7%3E3.0.CO;2-G
  • Bhavnani, D., Goldstick, J. E., Cevallos, W., Trueba, G., & Eisenberg, J. N. S. (2012). Synergistic effects between rotavirus and coinfecting pathogens on diarrheal disease: Evidence from a community-based study in northwestern Ecuador. American Journal of Epidemiology, 176, 387–395. doi:10.1093/aje/kws220
  • Bhutta, Z. A., Chopra, M., Axelson, H., Berman, P., Boerma, T., Bryce, J., … Wardlaw, T. (2010). Countdown to 2015 decade report (2000–10): Taking stock of maternal, newborn, and child survival. Lancet, 375, 2032–2044. doi:10.1016/S0140-6736(10)60678-2
  • Bhutta, Z. A., Das, J. K., Walker, N., Rizvi, A., Campbell, H., Rudan, I., & Black, R. E. (2013). Interventions to address deaths from childhood pneumonia and diarrhoea equitably: what works and at what cost? Lancet, 381, 1417–1429. doi:10.1016/S0140-6736(13)60648-0
  • Black, R. E., Allen, L. H., Bhutta, Z. A., Caulfield, L. E., de Onis, M., Ezzati, M., … Rivera, J. (2008). Maternal and child undernutrition: Global and regional exposures and health consequences. Lancet, 371, 243–260. doi:10.1016/S0140-6736(07)61690-0
  • Checkley, W., Buckley, G., Gilman, R. H., Assis, A. M., Guerrant, R. L., Morris, S. S., … Black, R. E. (2008). Multi-country analysis of the effects of diarrhoea on childhood stunting. International Journal of Epidemiology, 37, 816–830. doi:10.1093/ije/dyn099
  • Chen, C. C., Louie, S., McCormick, B., Walker, W. A., & Shi, H. N. (2005). Concurrent infection with an intestinal helminth parasite impairs host resistance to enteric Citrobacter rodentium and enhances Citrobacter-induced colitis in mice. Infections & Immunity, 73, 5468–5481. doi:10.1128/iai.73.9.5468-5481.2005
  • Chopra, M., Binkin, N. J., Mason, E., & Wolfheim, C. (2012). Integrated management of childhood illness: What have we learned and how can it be improved? Archives of Disease in Childhood, 97, 350–354. doi:10.1136/archdischild-2011-301191
  • Corel, J. L. (1975). The postnatal development of the human cerebral cortex. Cambridge, MA: Harvard University Press.
  • Coutinho, B. P., Oriá, R. B., Vieira, C. M. G., Sevilleja, J. E. A. D., Warren, C. A., Maciel, J. G., … Guerrant, R. L. (2008). Cryptosporidium infection causes undernutrition and, conversely, weanling undernutrition intensifies infection. The Journal of Parasitology, 94, 1225–1232. doi:10.1645/GE-1411.1
  • Cryan, J. F., & O'Mahony, S. M. (2011). The microbiome-gut-brain axis: From bowel to behavior. Neurogastroenterology and Motility, 23, 187–192. doi:10.1111/j.1365-2982.2010.01664.x
  • Farmer, P., & Becerra, M. (2001). Biosocial research and the TDR agenda. TDR News, 66, 5–7.
  • Ferreira, C. E.d. O., Raboni, S. M., Pereira, L. A., Nogueira, M. B., Vidal, L. R. R., & Almeida, S. M. (2012). Viral acute gastroenteritis: Clinical and epidemiological features of co-infected patients. Brazilian Journal of Infectious Diseases, 16, 267–272. doi:10.1590/S1413-86702012000300009
  • Fischer Walker, C., Perin, J., Aryee, M., Boschi-Pinto, C., & Black, R. (2012). Diarrhea incidence in low- and middle-income countries in 1990 and 2010: A systematic review. BMC Public Health, 12, 220–222. doi:10.1186/1471-2458-12-220
  • Fischer Walker, C., Rudan, I., Liu, L., Nair, H., Theodoratou, E., Bhutta, Z. A., … Black, R. (2013). Global burden of childhood pneumonia and diarrhoea. Lancet, 381, 1405–1416. doi:10.1016/S0140-6736(13)60222-6
  • Gill, C. J., Young, M., Schroder, K., Carvajal-Velez, L., McNabb, M., Aboubaker, S., … Bhutta, Z. A. (2013). Bottlenecks, barriers, and solutions: Results from multicountry consultations focused on reduction of childhood pneumonia and diarrhoea deaths. Lancet, 381, 1487–1498. doi:10.1016/S0140-6736(13)60314-1
  • Gourlay, A., Birdthistle, I., Mburu, G., Iorpenda, K., & Wringe, A. (2013). Barriers and facilitating factors to the uptake of antiretroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa: A systematic review. Journal of the International AIDS Society, 16, 18588 doi:10.7448/IAS.16.1.18588
  • Grenham, S., Clarke, G., Cryan, J., & Dinan, T. (2011). Brain-gut-microbe communication in health and disease. Frontiers in Physiology, 2, 94. doi:10.3389/fphys.2011.00094
  • Guerrant, D., Moore, S., Lima, A., Patrick, P., Schorling, J., & Guerrant, R. (1999). Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four-seven years later in a poor urban community in northeast Brazil. American Journal of Tropical Medicine Hygiene, 61, 707–713.
  • Haque, R., Snider, C., Liu, Y., Ma, J. Z., Liu, L., Nayak, U., … Petri, W. A., Jr. (2014). Oral polio vaccine response in breast fed infants with malnutrition and diarrhea. Vaccine, 32, 478–482. doi:10.1016/j.vaccine.2013.11.056
  • Holliday, M. A. (1986). Body composition and energy needs during growth. In F. Falkner & J. M. Tanner (Eds.), Human growth: A comprehensive treatise (Vol. 2, pp. 101–117). New York, NY: Plenum.
  • Huttenlocher, P. R. (2002). Neural plasticity: The effects of the environment on the development of the cerebral cortex. Perspectives in cognitive neuroscience. Cambridge, MA: Harvard University Press.
  • Keusch, G. T., Fontaine, O., Bhargava, A., Boschi-Pinto, C., Bhutta, Z. A., Gotuzzo, E., … Laxminarayan, R. (2006). Diarrheal diseases. In D. T. Jamison, J. G. Breman, A. R. Measham, G. Alleyne, M. Claeson, D. B. Evans, P. Jha, A. Mills, & P. Musgrove (Eds.), Disease control priorities in developing countries (2nd ed., pp. 371–388). New York, NY: Oxford University Press.
  • Kiliaan, A. J., Saunders, P. R., Bijlsma, P. B., Berin, M. C., Taminiau, J. A., Groot, J. A., & Perdue, M. H. (1998). Stress stimulates transepithelial macro molecular uptake in rat jejunum. American Journal of Physiology, 275, G1037–G1044.
  • Korpe, P. S., & Petri, W. A., Jr. (2012). Environmental enteropathy: Critical implications of a poorly understood condition. Trends in Molecular Medicine, 18, 328–336. doi:10.1016/j.molmed.2012.04.007
  • Kosek, M., Bern, C., & Guerrant, R. L. (2003). The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bulletin of the World Health Organization, 81(3), 197–204.
  • Kotloff, K. L., Nataro, J. P., Blackwelder, W. C., Nasrin, D., Farag, T. H., Panchalingam, S., … Levine, M. M. (2013). Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter study, GEMS): A prospective, case-control study. Lancet, 382, 209–222. doi:10.1016/S0140-6736(13)60844-2
  • Kurokawa, K., Itoh, T., Kuwahara, T., Oshima, K., Toh, H., Toyoda, A., … Hattori, M. (2007). Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes. DNA Research, 14, 169–181. doi:10.1093/dnares/dsm018
  • Lahariya, C., & Paul, V. K. (2010). Burden, differentials, and causes of child deaths in India. Indian Journal of Pediatrics, 77, 1312–1321. doi:10.1007/s12098-010-0185-z
  • Leischow, S. J., & Milstein, B. (2006). Systems thinking and modeling for public health practice. American Journal of Public Health, 96, 403–405. doi:10.2105/AJPH.2005.082842
  • Lin, A., Arnold, B. F., Afreen, S., Goto, R., Huda, T. M. N., Haque, R., … Luby, S. P. (2013). Household environmental conditions are associated with enteropathy and impaired growth in rural Bangladesh. American Journal of Tropical Medicine and Hygiene, 89(1), 130–137. doi:10.4269/ajtmh.12-0629
  • Lindert, K., Linder, A., Hobbs, J., & Briere, B. (2007). The nuts and bolts of Brazil's Bolsa Família Program: Implementing conditional cash transfers in a decentralized context. Retrieved from http://siteresources.worldbank.org/INTLACREGTOPLABSOCPRO/Resources/BRBolsaFamiliaDiscussionPaper.pdf
  • Lorntz, B., Soares, A. M., Moore, S. R., Pinkerton, R., Gansneder, B., Bovbjerg, V. E., … Guerrant, R. L. (2006). Early childhood diarrhea predicts impaired school performance. The Pediatric Infectious Disease Journal, 25, 513–520. doi:10.1097/01.inf.0000219524.64448.90
  • Lynn, R., & Vanhanen, T. (2006). IQ and global inequality. Augusta, GA: Washington Summit.
  • Mara, D. D. (2003). Water, sanitation and hygiene for the health of developing nations. Public Health, 117, 452–456. doi:10.1016/S0033-3506(03)00143-4
  • Mayer, L. (2003). Mucosal immunity. Pediatrics, 111, 1595–1600.
  • McKeown, T. (1978). Determinants of health. Human nature magazine. New York, NY: Harcourt Brace.
  • Ministerio do Desenvolvimento Social e Combate a Fome [Minstry of Social Development and Hunger Alleviation]. (2013). Matriz de Informação Social [Social information matrix]. Retrieved from http://aplicacoes.mds.gov.br/sagi/mi2007/tabelas/mi_social.php&
  • Moore, S. R., Lima, A. A. M., Conaway, M. R., Schorling, J. B., Soares, A. M., & Guerrant, R. L. (2001). Early childhood diarrhoea and helminthiases associate with long-term linear growth faltering. International Journal of Epidemiology, 30, 1457–1464. doi:10.1093/ije/30.6.1457
  • Niehaus, M. D., Moore, S. R., Patrick, P. D., Derr, L. L., Lorntz, B., Lima, A. A., & Guerrant, R. L. (2002). Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown. American Journal of Tropical Medicine and Hygiene, 66, 590–593.
  • O'Mahony, S. M., Marchesi, J. R., Scully, P., Codling, C., Ceolho, A.-M., Quigley, E. M. M., … Dinan, T. G. (2009). Early life stress alters behavior, immunity, and microbiota in rats: Implications for irritable bowel syndrome and psychiatric illnesses. Biological Psychiatry, 65, 263–267. doi:10.1016/j.biopsych.2008.06.026
  • Palmer, C., Bik, E. M., Digiulio, D. B., Relman, D. A., & Brown, P. O. (2007). Development of the human infant intestinal microbiota. PLoS Biology, 5, e177. doi:10.1371/journal.pbio.0050177
  • Panagariya, A. (2012, September). The myth of childhood malnutrition in India. India: Reforms, Economic Transformation and the Socially Disadvantaged. Columbia University, NY.
  • Petri, W. A., Jr., Miller, M., Binder, H. J., Levine, M. M., Dillingham, R., & Guerrant, R. L. (2008). Enteric infections, diarrhea, and their impact on function and development. Journal of Clinical Investigation, 118, 1277–1290. doi:10.1172/JCI34005
  • Quigley, E. M. M. (2008). Probiotics in functional gastrointestinal disorders: What are the facts?Current Opinion in Pharmacology, 8, 704–708. doi:10.1016/j.coph.2008.08.007
  • Rasella, D., Aquino, R., Santos, C. A., Paes-Sousa, R., & Barreto, M. L. (2013). Effect of a conditional cash transfer programme on childhood mortality: A nationwide analysis of Brazilian municipalities. Lancet, 382(9886), 57–64. doi:10.1016/S0140-6736(13)60715-1
  • Rhee, S. H., Pothoulakis, C., & Mayer, E. A. (2009). Principles and clinical implications of the brain-gut-enteric microbiota axis. Nature Reviews. Gastroenterology and Hepatology, 6, 306–314. doi:10.1038/nrgastro.2009.35
  • Rice, D., & Barone, S. (2000). Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models. Environmental Health Perspectives, 108(Suppl. 3), 511–533. doi:10.1289/ehp.00108s3511
  • Schorling, J. B., & Guerrant, R. L., Moy, R. J. D., Choto, R., Booth, I. W., & Mcneish, A. S. (1990). Diarrhoea and catch-up growth. Lancet, 335, 599–600. doi:10.1016/0140-6736(90)90378-I
  • Sekirov, I., Russell, S. L., Antunes, L. C. M., & Finlay, B. B. (2010). Gut microbiota in health and disease. Physiological Reviews, 90, 859–904. doi:10.1152/physrev.00045.2009
  • Singer, M. (2009). Introduction to syndemics: A systems approach to public and community health. San Francisco, CA: Jossey-Bass.
  • Singer, M. (2010). Pathogen-pathogen interaction: A syndemic model of complex biosocial processes in disease. Virulence, 1(1), 10–18. doi:10.4161/viru.1.1.9933
  • Sinha, A., SenGupta, S., Guin, S., Dutta, S., Ghosh, S., Mukherjee, P., … Nandy, R. K. (2013). Culture-independent real-time PCR reveals extensive polymicrobial infections in hospitalized diarrhoea cases in Kolkata, India. Clinical Microbiology and Infection, 19, 173–180. doi:10.1111/j.1469-0691.2011.03746.x
  • Spears, D. (2013). How much international variation in child height can sanitation explain? Policy Research Working Paper 6351. New York, NY: World Bank, Sustainable Development Network, Water and Sanitation Program.
  • Strachan, D. L., Kallander, K., Ten Asbroek, A. H., Kirkwood, B., Meek, S. R., Benton, L., … Hill, Z. (2012). Interventions to improve motivation and retention of community health workers delivering integrated community case management (iCCM): Stakeholder perceptions and priorities. American Journal of Tropical Medicine and Hygiene, 87(Suppl. 5), 111–119. doi:10.4269/ajtmh.2012.12-0030
  • Su, C. W., Cao, Y., Zhang, M., Kaplan, J., Su, L., Fu, Y., … Shi, H. N. (2012). Helminth infection impairs autophagy-mediated killing of bacterial enteropathogens by macrophages. Journal of Immunology, 189, 1459–1466. doi:10.4049/jimmunol.1200484
  • Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X.-N., … Koga, Y. (2004). Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. The Journal of Physiology, 558, 263–275. doi:10.1113/jphysiol.2004.063388
  • Tarozzi, A. (2008). Growth reference charts and the nutritional status of Indian children. Economics and Human Biology, 6, 455–468. doi:10.1016/j.ehb.2008.07.004
  • Tazume, S., Ozawa, A., Yamamoto, T., Takahashi, Y., Takeshi, K., Saidi, S. M., … Waiyaki, P. G. (1993). Ecological study on the intestinal bacterial flora of patients with diarrhea. Clinical Infectious Diseases, 16(Suppl. 2), S77–S82. doi:10.1093/clinids/16.Supplement_2.S77
  • Tazume, S., Takeshi, K., Saidi, S. M., Ichoroh, C. G., Mutua, W. R., Waiyaki, P. G., & Ozawa, A. (1990). Ecological studies on intestinal microbial flora of Kenyan children with diarrhoea. Journal of Tropical Medicine and Hygiene, 93, 215–221.
  • Thompson, R. A., & Nelson, C. A. (2001). Developmental science and the media. Early brain development. The American Psychologist, 56(1), 5–15. doi:10.1037/0003-066X.56.1.5
  • Valentini, D., Vittucci, A. C., Grandin, A., Tozzi, A. E., Russo, C., Onori, M., … Villani, A. (2013). Coinfection in acute gastroenteritis predicts a more severe clinical course in children. European Journal of Clinical Microbiology and Infectious Diseases, 32, 909–915. doi:10.1007/s10096-013-1825-9
  • van Eijk, A. M., Brooks, J. T., Adcock, P. M., Garrett, V., Eberhard, M., Rosen, D. H., … Slutsker, L. (2010). Diarrhea in children less than two years of age with known HIV status in Kisumu, Kenya. International Journal of Infectious Diseases, 14, e220–e225. doi:10.1016/j.ijid.2009.06.001
  • van Koppen, B., Sokile, C. S., Hatibu, N., Lankford, B. A., Mahoo, H., & Yanda, P. Z. (2004). Formal water rights in rural Tanzania: Deepening the dichotomy? Colombo: International Water Management Institute.
  • Walker, S. P., Wachs, T. D., Grantham-McGregor, S., Black, M. M., Nelson, C. A., Huffman, S. L., … Richter, L. (2011). Inequality in early childhood: Risk and protective factors for early child development. Lancet, 378, 1325–1338. doi:10.1016/S0140-6736(11)60555-2
  • Wegman, M. (2001). Infant mortality in the 20th century, dramatic but uneven progress. The Journal of Nutrition, 131, 401S–408S.
  • Weng, M., Huntley, D., Huang, I.-F., Foye-Jackson, O., Wang, L., Sarkissian, A., … Shi, H. N. (2007). Alternatively activated macrophages in intestinal helminth infection: Effects on concurrent bacterial colitis. Journal of Immunology, 179, 4721–4731. doi:10.4049/jimmunol.179.7.4721
  • WHO. (2013a). Diarrhea fact sheet. Retrieved August, 8, 2013, from http://www.who.int/mediacentre/factsheets/fs330/en/index.html
  • WHO. (2013b). Ending preventable deaths from pneumonia and diarrhoea by 2025. Retrieved from http://www.who.int/maternal_child_adolescent/news_events/news/2013/gappd_launch/en/index.html
  • WHO/UNICEF. (2012a). Levels and trends in child mortality. Geneva: The UN Inter-agency Group for Child Mortality Estimation UNICEF/WHO/World Bank/United Nations.
  • WHO/UNICEF. (2012b). Progress on drinking water and sanitation: 2012 update. Geneva: Author.
  • World Bank. (1996). Staff Appraisal Report, Tanzania. River basin management and smallholder irrigation improvement project (Report No. 15122-TA). Washington, DC: Agriculture and Environment Operations, Eastern Africa Department.

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