Antithyroid drug therapy in pregnancy: a review of guideline recommendations

References

• Carlé A, Pedersen IB, Knudsen N, et al. Epidemiology of subtypes of hyperthyroidism in Denmark: a population-based study. Eur J Endocrinol. 2011;164:801–809.
   PubMed Web of Science ®Google Scholar
• Weetman AP. Graves’ disease. N Engl J Med. 2000;343:1236–1248.
   PubMed Web of Science ®Google Scholar
• Burch HB, Cooper DS. Management of Graves disease: a review. JAMA. 2015;314:2544–2554. Epub 2015/12/17.
   PubMed Web of Science ®Google Scholar
• Tozzoli R, Bagnasco M, Giavarina D, et al. TSH receptor autoantibody immunoassay in patients with Graves’ disease: improvement of diagnostic accuracy over different generations of methods. Systematic review and meta-analysis. Autoimmun Rev. 2012;12:107–113. Epub 2012/07/11.
   PubMed Web of Science ®Google Scholar
• Okosieme OE, Lazarus JH. Important considerations in the management of Graves’ disease in pregnant women. Expert Rev Clin Immunol. 2015;11:947–957. Epub 2015/06/05.
   PubMed Web of Science ®Google Scholar
• Okosieme OE, Marx H, Lazarus JH. Medical management of thyroid dysfunction in pregnancy and the postpartum. Expert Opin Pharmacother. 2008;9:2281–2293.
   PubMed Web of Science ®Google Scholar
• McKenzie JM, Zakarija M. Fetal and neonatal hyperthyroidism and hypothyroidism due to maternal TSH receptor antibodies. Thyroid. 1992;2:155–159. Epub 1992/01/01.
   PubMed Web of Science ®Google Scholar
• Evans C, Gregory JW, Barton J, et al. Transient congenital hypothyroidism due to thyroid-stimulating hormone receptor blocking antibodies: a case series. Ann Clin Biochem. 2011;48:386–390.
   PubMed Web of Science ®Google Scholar
• Okosieme OE, Lazarus JH. Current trends in antithyroid drug treatment of Graves’ disease. Expert Opin Pharmacother. 2016;17:2005–2017. Epub 2016/09/13.
   PubMed Web of Science ®Google Scholar
• Ross DS, Burch HB, Cooper DS, et al. 2016 American thyroid association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis. Thyroid. 2016;26:1343–1421. Epub 2016/08/16.
   PubMed Web of Science ®Google Scholar
• Stagnaro-Green A, Abalovich M, Alexander E, et al. Guidelines of the American thyroid association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid. 2011;21:1081–1125.
   PubMed Web of Science ®Google Scholar
• De Groot L, Abalovich M, Alexander EK, et al. Management of thyroid dysfunction during pregnancy and postpartum: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2012;97:2543–2565.
   PubMed Web of Science ®Google Scholar
• Negro R, Beck-Peccoz P, Chiovato L, et al. Hyperthyroidism and pregnancy. An Italian Thyroid Association (AIT) and Italian Association of Clinical Endocrinologists (AME) joint statement for clinical practice. J Endocrinol Invest. 2011;34:225–231.
   PubMed Web of Science ®Google Scholar
• ACOG. Practice bulletin no. 148: thyroid disease in pregnancy. Obstet Gynecol. 2015:125:996–1005. Epub 2015/03/24.
   PubMedGoogle Scholar
• Alexander EK, Pearce EN, Brent GA, et al. 2016 guidelines of the american thyroid association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid. 2017;27:315–389. Epub 2017/01/07.
   PubMed Web of Science ®Google Scholar
• Maia AL, Scheffel RS, Meyer EL, et al. The Brazilian consensus for the diagnosis and treatment of hyperthyroidism: recommendations by the thyroid department of the brazilian society of endocrinology and metabolism. Arq Bras Endocrinol Metabol. 2013;57:205–232.
   PubMedGoogle Scholar
• Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and postpartum: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2007;92:S1–S47.
   PubMed Web of Science ®Google Scholar
• Bahn Chair RS, Burch HB, Cooper DS, et al. Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American thyroid association and American association of clinical endocrinologists. Thyroid. 2011;21:593–646. Epub 2011/04/23.
   PubMed Web of Science ®Google Scholar
• ACOG Practice Bulletin. Clinical management guidelines for obstetrician-gynecologists. Number 37, August 2002. (Replaces Practice Bulletin Number 32, November 2001). Thyroid disease in pregnancy. Obstet Gynecol. 2002;100:387–396. Epub 2002/08/09.
   PubMedGoogle Scholar
• Brouwers MC, Kho ME, Browman GP, et al. The Global Rating Scale complements the AGREE II in advancing the quality of practice guidelines. J Clin Epidemiol. 2012;65:526–534. Epub 2011/12/23.
   PubMed Web of Science ®Google Scholar
• Brouwers MC, Kerkvliet K, Spithoff K. The AGREE Reporting Checklist: a tool to improve reporting of clinical practice guidelines. BMJ. 2016;352:i1152. Epub 2016/03/10.
   PubMed Web of Science ®Google Scholar
• Brent GA. Maternal thyroid function: interpretation of thyroid function tests in pregnancy. Clin Obstet Gynecol. 1997;40:3–15. Epub 1997/03/01.
   PubMed Web of Science ®Google Scholar
• Glinoer D. The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocr Rev. 1997;18:404–433. Epub 1997/06/01.
   PubMed Web of Science ®Google Scholar
• Casey BM, Dashe JS, Wells CE, et al. Subclinical hyperthyroidism and pregnancy outcomes. Obstet Gynecol. 2006;107:337–341. Epub 2006/02/02.
   PubMed Web of Science ®Google Scholar
• Medici M, Timmermans S, Visser W, et al. Maternal thyroid hormone parameters during early pregnancy and birth weight: the generation R study. J Clin Endocrinol Metab. 2013;98:59–66.
   PubMed Web of Science ®Google Scholar
• Korevaar TI, Medici M, de Rijke YB, et al. Ethnic differences in maternal thyroid parameters during pregnancy: the generation R study. J Clin Endocrinol Metab. 2013;98:3678–3686. Epub 2013/07/10.
   PubMed Web of Science ®Google Scholar
• Medici M, Korevaar TI, Visser WE, et al. Thyroid function in pregnancy: what is normal? Clin Chem. 2015;61:704–713. Epub 2015/04/02.
   PubMed Web of Science ®Google Scholar
• Matthews DC, Syed AA. The role of TSH receptor antibodies in the management of Graves’ disease. Eur J Intern Med. 2011;22:213–216. Epub 2011/05/17.
   PubMed Web of Science ®Google Scholar
• Glinoer D. Thyroid hyperfunction during pregnancy. Thyroid. 1998;8:859–864. Epub 1998/10/20.
   PubMed Web of Science ®Google Scholar
• Lazarus JH. Pre-conception counselling in graves’ disease. Eur Thyroid J. 2012;1:24–29.
   PubMedGoogle Scholar
• Rotondi M, Cappelli C, Pirali B, et al. The effect of pregnancy on subsequent relapse from Graves’ disease after a successful course of antithyroid drug therapy. J Clin Endocrinol Metab. 2008;93:3985–3988.
   PubMed Web of Science ®Google Scholar
• Laurberg P, Krejbjerg A, Andersen SL. Relapse following antithyroid drug therapy for Graves’ hyperthyroidism. Curr Opin Endocrinol Diabetes Obes. 2014;21:415–421. Epub 2014/08/12.
   PubMed Web of Science ®Google Scholar
• Laurberg P, Bournaud C, Karmisholt J, et al. Management of Graves’ hyperthyroidism in pregnancy: focus on both maternal and foetal thyroid function, and caution against surgical thyroidectomy in pregnancy. Eur J Endocrinol. 2009;160:1–8. Epub 2008/10/14.
   PubMed Web of Science ®Google Scholar
• Cooper DS. Antithyroid drugs. N Engl J Med. 2005;352:905–917.
   PubMed Web of Science ®Google Scholar
• Cooper DS. Antithyroid drugs in the management of patients with Graves’ disease: an evidence-based approach to therapeutic controversies. J Clin Endocrinol Metab. 2003;88:3474–3481. Epub 2003/08/14.
   PubMed Web of Science ®Google Scholar
• Taylor PN, Vaidya B. Side effects of anti-thyroid drugs and their impact on the choice of treatment for thyrotoxicosis in pregnancy. Eur Thyroid J. 2012;1:176–185.
   PubMedGoogle Scholar
• Nakamura H, Miyauchi A, Miyawaki N, et al. Analysis of 754 cases of antithyroid drug-induced agranulocytosis over 30 years in Japan. J Clin Endocrinol Metab. 2013;98:4776–4783. Epub 2013/09/24.
   PubMed Web of Science ®Google Scholar
• Calhoun DA, Rosa C, Christensen RD. Transplacental passage of recombinant human granulocyte colony-stimulating factor in women with an imminent preterm delivery. Am J Obstet Gynecol. 1996;174:1306–1311. Epub 1996/04/01.
   PubMed Web of Science ®Google Scholar
• Bahn RS, Burch HS, Cooper DS, et al. The role of propylthiouracil in the management of graves’ disease in adults: report of a meeting jointly sponsored by the American thyroid association and the food and drug administration. Thyroid. 2009;19:673–674. Epub 2009/07/09.
   PubMedGoogle Scholar
• Cooper DS, Rivkees SA. Putting propylthiouracil in perspective. J Clin Endocrinol Metab. 2009;94:1881–1882.
   PubMed Web of Science ®Google Scholar
• Wang MT, Lee WJ, Huang TY, et al. Antithyroid drug-related hepatotoxicity in hyperthyroidism patients: a population-based cohort study. Br J Clin Pharmacol. 2014;78:619–629. Epub 2014/10/04.
   PubMed Web of Science ®Google Scholar
• Clementi M, Di Gianantonio E, Pelo E, et al. Methimazole embryopathy: delineation of the phenotype. Am J Med Genet. 1999;83:43–46.
   PubMed Web of Science ®Google Scholar
• Karlsson FA, Axelsson O, Melhus H. Severe embryopathy and exposure to methimazole in early pregnancy. J Clin Endocrinol Metab. 2002;87:947–949. Epub 2002/02/12.
   PubMed Web of Science ®Google Scholar
• Di Gianantonio E, Schaefer C, Mastroiacovo PP, et al. Adverse effects of prenatal methimazole exposure. Teratology. 2001;64:262–266.
   PubMedGoogle Scholar
• Clementi M, Di Gianantonio E, Cassina M, et al. Treatment of hyperthyroidism in pregnancy and birth defects. J Clin Endocrinol Metab. 2010;95:E337–41.
   PubMed Web of Science ®Google Scholar
• Yoshihara A, Noh J, Yamaguchi T, et al. Treatment of graves’ disease with antithyroid drugs in the first trimester of pregnancy and the prevalence of congenital malformation. J Clin Endocrinol Metab. 2012;97:2396–2403.
   PubMed Web of Science ®Google Scholar
• Andersen SL, Olsen J, Wu CS, et al. Birth defects after early pregnancy use of antithyroid drugs: a Danish nationwide study. J Clin Endocrinol Metab. 2013;98:4373–4381.
   PubMed Web of Science ®Google Scholar
• Andersen SL, Olsen J, Wu CS, et al. Severity of birth defects after propylthiouracil exposure in early pregnancy. Thyroid. 2014;24:1533–1540. Epub 2014/06/26.
   PubMed Web of Science ®Google Scholar
• Chen CH, Xirasagar S, Lin CC, et al. Risk of adverse perinatal outcomes with antithyroid treatment during pregnancy: a nationwide population-based study. BJOG. 2011;118:1365–1373. Epub 2011/06/01.
   PubMed Web of Science ®Google Scholar
• Mandel SJ, Brent GA, Larsen PR. Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis. Thyroid. 1994;4:129–133. Epub 1994/01/01.
   PubMed Web of Science ®Google Scholar
• Momotani N, Ito K, Hamada N, et al. Maternal hyperthyroidism and congenital malformation in the offspring. Clin Endocrinol (Oxf). 1984;20:695–700. Epub 1984/06/01.
   PubMed Web of Science ®Google Scholar
• Korelitz JJ, McNally DL, Masters MN, et al. Prevalence of thyrotoxicosis, antithyroid medication use, and complications among pregnant women in the United States. Thyroid. 2013;23:758–765. Epub 2012/12/01.
   PubMed Web of Science ®Google Scholar
• Li X, Liu GY, Ma JL, et al. Risk of congenital anomalies associated with antithyroid treatment during pregnancy: a meta-analysis. Clinics (Sao Paulo, Brazil). 2015;70:453–459. Epub 2015/06/25.
   PubMed Web of Science ®Google Scholar
• Li H, Zheng J, Luo J, et al. Congenital anomalies in children exposed to antithyroid drugs in-utero: a meta-analysis of cohort studies. Plos One. 2015;10:e0126610. Epub 2015/05/15.
   PubMed Web of Science ®Google Scholar
• Laurberg P, Andersen SL. Therapy of endocrine disease: antithyroid drug use in early pregnancy and birth defects: time windows of relative safety and high risk? Eur J Endocrinol. 2014;171:R13–20.
   PubMed Web of Science ®Google Scholar
• Korevaar TI, Muetzel R, Medici M, et al. Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study. Lancet Diabetes Endocrinol. 2016;4:35–43. Epub 2015/10/27.
   PubMed Web of Science ®Google Scholar
• Abeillon-Du Payrat J, Chikh K, Bossard N, et al. Predictive value of maternal second-generation thyroid-binding inhibitory immunoglobulin assay for neonatal autoimmune hyperthyroidism. Eur J Endocrinol. 2014;171:451–460.
   PubMed Web of Science ®Google Scholar
• Laurberg P, Nygaard B, Glinoer D, et al. Guidelines for TSH-receptor antibody measurements in pregnancy: results of an evidence-based symposium organized by the European Thyroid Association. Eur J Endocrinol. 1998;139:584–586. Epub 1999/01/23.
   PubMed Web of Science ®Google Scholar
• Zimmerman D. Fetal and neonatal hyperthyroidism. Thyroid. 1999;9:727–733. Epub 1999/08/14.
   PubMed Web of Science ®Google Scholar
• Donnelly MA, Wood C, Casey B, et al. Early severe fetal Graves disease in a mother after thyroid ablation and thyroidectomy. Obstet Gynecol. 2015;125:1059–1062. Epub 2015/02/25.
   PubMed Web of Science ®Google Scholar
• Johansen K, Andersen AN, Kampmann JP, et al. Excretion of methimazole in human milk. Eur J Clin Pharmacol. 1982;23:339–341. Epub 1982/10/01.
   PubMed Web of Science ®Google Scholar
• Azizi F, Amouzegar A. Management of hyperthyroidism during pregnancy and lactation. Eur J Endocrinol. 2011;164:871–876.
   PubMed Web of Science ®Google Scholar
• Woolf SH, Grol R, Hutchinson A, et al. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318:527–530. Epub 1999/02/19.
   PubMed Web of Science ®Google Scholar
• Deutsch SC, Denton M, Borenstein J. Clinical practice guidelines: a tool to help provide quality care. Geriatrics. 1998;53:57, 61-4, 70, 3-4. quiz 5. Epub 1998/03/25.
   PubMedGoogle Scholar
• Taylor PN, Minassian C, Rehman A, et al. TSH levels and risk of miscarriage in women on long-term levothyroxine: a community-based study. J Clin Endocrinol Metab. 2014;99:3895–3902.
   PubMed Web of Science ®Google Scholar
• Khan I, Witczak JK, Hadjieconomou S, et al. Preconception thyroid-stimulating hormone and pregnancy outcomes in women with hypothyroidism. Endocr Pract. 2013;19:656–662.
   PubMed Web of Science ®Google Scholar
• Burch HB, Burman KD, Cooper DS. A 2011 survey of clinical practice patterns in the management of Graves’ disease. J Clin Endocrinol Metab. 2012;97:4549–4558. Epub 2012/10/09.
   PubMed Web of Science ®Google Scholar
• Pedersen RN, Calzolari E, Husby S, et al. Oesophageal atresia: prevalence, prenatal diagnosis and associated anomalies in 23 European regions. Arch Dis Child. 2012;97:227–232. Epub 2012/01/17.
   PubMed Web of Science ®Google Scholar
• Case AP, Mitchell LE. Prevalence and patterns of choanal atresia and choanal stenosis among pregnancies in Texas, 1999-2004. Am J Med Genet A. 2011;155a:786–791. Epub 2011/03/19.
   PubMed Web of Science ®Google Scholar
• Khan I, Okosieme OE, Lazarus JH. Current challenges in the pharmacological management of thyroid dysfunction in pregnancy. Expert Rev Clin Pharmacol. 2017;10:97–109. Epub 2016/10/27.
   PubMed Web of Science ®Google Scholar
• Kessler L, Palla J, Baru JS, et al. Lithium as an adjunct to radioactive iodine for the treatment of hyperthyroidism: a systematic review and meta-analysis. Endocr Pract. 2014;20:737–745. Epub 2014/05/06.
   PubMed Web of Science ®Google Scholar
• Kaykhaei MA, Shams M, Sadegholvad A, et al. Low doses of cholestyramine in the treatment of hyperthyroidism. Endocrine. 2008;34:52–55. Epub 2008/10/24.
   PubMed Web of Science ®Google Scholar
• Yoshihara A, Noh JY, Watanabe N, et al. Substituting Potassium iodide for methimazole as the treatment for graves’ disease during the first trimester may reduce the incidence of congenital anomalies: a retrospective study at a single medical institution in Japan. Thyroid. 2015;25:1155–1161. Epub 2015/07/30.
   PubMed Web of Science ®Google Scholar
• Neumann S, Place RF, Krieger CC, et al. Future Prospects for the treatment of Graves’ Hyperthyroidism and eye disease. Horm Metab Res. 2015;47:789–796. Epub 2015/07/23.
   PubMed Web of Science ®Google Scholar
• McKnight RF, Adida M, Budge K, et al. Lithium toxicity profile: a systematic review and meta-analysis. Lancet. 2012;379:721–728. Epub 2012/01/24.
   PubMed Web of Science ®Google Scholar
• Uchida T, Goto H, Kasai T, et al. Therapeutic effectiveness of potassium iodine in drug-naive patients with Graves’ disease: a single-center experience. Endocrine. 2014;47:506–511. Epub 2014/02/05.
   PubMed Web of Science ®Google Scholar
• Gershengorn MC, Neumann S. Update in TSH receptor agonists and antagonists. J Clin Endocrinol Metab. 2012;97:4287–4292. Epub 2012/09/29.
   PubMed Web of Science ®Google Scholar