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Editorial

Does abdominal obesity influence immunological response to SARS-CoV-2 infection?

ORCID Icon, ORCID Icon, & ORCID Icon
Pages 271-272 | Received 29 Jul 2021, Accepted 24 Aug 2021, Published online: 17 Sep 2021

References

  • Pediconi F, Rizzo V, Schiaffino S, et al. Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients. Obes Res Clin Pract. 2021 Jan-Feb;15(1):89–92.
  • Foldi M, Farkas N, Kiss S, et al. Visceral adiposity elevates the risk of critical condition in COVID-19: a systematic review and meta-analysis. Obesity (Silver Spring). 2021 Mar;29(3):521–528.
  • Favre G, Legueult K, Pradier C, et al. Visceral fat is associated to the severity of COVID-19. Metabolism. 2021 Feb;115:154440.
  • Hendren NS, de Lemos JA, Ayers C, et al. Association of body mass index and age with morbidity and mortality in patients hospitalized with COVID-19: results from the American heart association COVID-19 cardiovascular disease registry. Circulation. 2021 Jan 12;143(2):135–144.
  • Gao M, Piernas C, Astbury NM, et al. Associations between body-mass index and COVID-19 severity in 6.9 million people in England: a prospective, community-based, cohort study. Lancet Diabetes Endocrinol. 2021 Jun;9(6):350–359.
  • Covid-19 and obesity: the 2021 atlas. World Obesity Federation; 2021 [cited 2021 Jul 28]. Available from: https://www.worldobesity.org/
  • Watanabe M, Balena A, Tuccinardi D, et al. Central obesity, smoking habit, and hypertension are associated with lower antibody titres in response to COVID-19 mRNA vaccine. Diabetes Metab Res Rev. 2021 May 6;e3465.
  • Sanchis-Gomar F, Lavie CJ, Mehra MR, et al. Obesity and outcomes in COVID-19: when an epidemic and pandemic collide. Mayo Clin Proc. 2020 Jul;95(7):1445–1453.
  • Aggarwal G, Cheruiyot I, Aggarwal S, et al. Association of cardiovascular disease with coronavirus disease 2019 (COVID-19) severity: a meta-analysis. Curr Probl Cardiol. 2020 Aug;45(8):100617.
  • Perez-Galarza J, Procel C, Canadas C, et al. Immune response to SARS-CoV-2 infection in obesity and T2D: literature review. Vaccines (Basel). 2021 Jan 29;9(2):102.
  • Lavie CJ, Sanchis-Gomar F, Henry BM, et al. COVID-19 and obesity: links and risks. Expert Rev Endocrinol Metab. 2020 Jul;15(4):215–216.
  • Alvarez-Garcia J, Lee S, Gupta A, et al. Prognostic impact of prior heart failure in patients hospitalized with COVID-19. J Am Coll Cardiol. 2020 Nov 17;76(20):2334–2348.
  • Van Zelst CM, Janssen ML, Pouw N, et al. Analyses of abdominal adiposity and metabolic syndrome as risk factors for respiratory distress in COVID-19. BMJ Open Respir Res. 2020 Dec;7(1):e000792.
  • Dietz W, Santos-Burgoa C. Obesity and its implications for COVID-19 mortality. Obesity (Silver Spring). 2020 Jun;28(6):1005.
  • Fruhbeck G, Catalan V, Rodriguez A, et al. Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome. Sci Rep. 2017 Jul 26;7(1):6619.
  • Liu R, Nikolajczyk BS. Tissue immune cells fuel obesity-associated inflammation in adipose tissue and beyond. Front Immunol. 2019;10:1587.
  • Richter FC, Alrubayyi A, Teijeira Crespo A, et al. Impact of obesity and SARS-CoV-2 infection: implications for host defence - a living review. Oxf Open Immunol. 2021;2(1):iqab001.
  • Huttunen R, Syrjanen J. Obesity and the risk and outcome of infection. Int J Obes (Lond). 2013 Mar;37(3):333–340.
  • Alwarawrah Y, Kiernan K, MacIver NJ. Changes in nutritional status impact immune cell metabolism and function. Front Immunol. 2018;9:1055.
  • Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7265–7270.
  • Watanabe M, Risi R, Tuccinardi D, et al. Obesity and SARS-CoV-2: a population to safeguard. Diabetes Metab Res Rev. 2020;21:e3325.
  • Leitner DR, Fruhbeck G, Yumuk V, et al. Obesity and type 2 diabetes: two diseases with a need for combined treatment strategies - EASO can lead the way. Obes Facts. 2017;10(5):483–492.
  • Fruhbeck G, Baker JL, Busetto L, et al., European association for the study of obesity position statement on the global COVID-19 pandemic. Obes Facts. 2020;13(2):292–296.
  • Vecchie A, Dallegri F, Carbone F, et al. Obesity phenotypes and their paradoxical association with cardiovascular diseases. Eur J Intern Med. 2018 Feb;48:6–17.

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