Further understanding of thyroid function in pregnant women

References

• Yuan N, Wang L, and Li Z, et al. Thyroid diseases during pregnancy: bibliometric analysis of scientific publications. Endocr Metab Immune Disord Drug Targets. 2021 Feb 3;21(2):360–364.
   PubMedGoogle Scholar
• Alexander EK, Pearce EN, and Brent GA, et al. Guidelines of the American thyroid association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid. 2017 Mar;27(3):315–389.
   PubMed Web of Science ®Google Scholar
• Andersen SL, Andersen S. Turning to thyroid disease in pregnant women. Eur Thyroid J. 2020 Sep;9(5):225–233.
   PubMedGoogle Scholar
• Stagnaro-Green A, Pearce E. Thyroid disorders in pregnancy. Nat Rev Endocrinol. 2012 Nov;8(11):650–658.
   PubMedGoogle Scholar
• Benvenga S, Capodicasa G, Perelli S, et al. Support for the upregulation of serum thyrotropin by estrogens coming from the increased requirement of levothyroxine in one gynecomastic patient with excess of thyroxine-binding globulin secondary to exposure to exogenous estrogens. J Clin Transl Endocrinol: Case Rep. 2018 2018 dec 01;10:21–24.
   Google Scholar
• Sterrett M. Maternal and fetal thyroid physiology. Clin Obstet Gynecol. 2019 Jun;62(2):302–307.
   PubMedGoogle Scholar
• Glinoer D. The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocr Rev. 1997 Jun;18(3):404–433.
   PubMed Web of Science ®Google Scholar
• Glinoer D. Pregnancy and iodine. Thyroid. 2001 May;11(5):471–481.
   PubMedGoogle Scholar
• Fadeyev V, Lesnikova S, Melnichenko G. Prevalence of thyroid disorders in pregnant women with mild iodine deficiency. Gynecol Endocrinol. 2003 Oct;17(5):413–418.
   PubMed Web of Science ®Google Scholar
• Vannucchi G, Covelli D, Vigo B, et al. Thyroid volume and serum calcitonin changes during pregnancy. J Endocrinol Invest. 2017 Jul;40(7):727–732.
   PubMedGoogle Scholar
• Hershman JM. Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid. Best Pract Res Clin Endocrinol Metab. 2004 Jun;18(2):249–265.
   PubMed Web of Science ®Google Scholar
• Silva JF, Ocarino NM, Serakides R. Thyroid hormones and female reproduction. Biol Reprod. 2018 Nov 1;99(5):907–921.
   PubMed Web of Science ®Google Scholar
• Adu-Gyamfi EA, Wang YX, Ding YB. The interplay between thyroid hormones and the placenta: a comprehensive review†. Biol Reprod. 2020 Feb 12;102(1):8–17.
   PubMed Web of Science ®Google Scholar
• Orozco A, Valverde RC, Olvera A, et al. Iodothyronine deiodinases: a functional and evolutionary perspective. J Endocrinol. 2012 Nov;215(2):207–219.
   PubMedGoogle Scholar
• Eerdekens A, Verhaeghe J, Darras V, et al. The placenta in fetal thyroid hormone delivery: from normal physiology to adaptive mechanisms in complicated pregnancies. J Matern Fetal Neonatal Med. 2020 Nov;33(22):3857–3866.
   PubMed Web of Science ®Google Scholar
• Mallawa Kankanamalage O, Zhou Q, Li X. Understanding the pathogenesis of gestational hypothyroidism. Front Endocrinol (Lausanne). 2021;12:653407.
   PubMedGoogle Scholar
• Koukkou E, Ilias I, Alexiou M, et al. Urine selenium changes during pregnancy do not correlate with thyroid autoantibodies in a mildly iodine deficient population. Biol Trace Elem Res. 2014 Jan;157(1):9–13.
   PubMedGoogle Scholar
• Chung HR. Iodine and thyroid function. Ann Pediatr Endocrinol Metab. 2014 Mar;19(1):8–12.
   PubMedGoogle Scholar
• Rodriguez-Diaz E, Pearce EN. Iodine status and supplementation before, during, and after pregnancy. Best Pract Res Clin Endocrinol Metab. 2020 Jul;34(4):101430.
   PubMedGoogle Scholar
• Leung AM, Pearce EN, Braverman LE. Iodine nutrition in pregnancy and lactation. Endocrinol Metab Clin North Am. 2011 Dec;40(4):765–777.
   PubMedGoogle Scholar
• Gérard AC, Poncin S, Caetano B, et al. Iodine deficiency induces a thyroid stimulating hormone-independent early phase of microvascular reshaping in the thyroid. Am J Pathol. 2008 Mar;172(3):748–760.
   PubMedGoogle Scholar
• Batistuzzo A, Ribeiro MO. Clinical and subclinical maternal hypothyroidism and their effects on neurodevelopment, behavior and cognition. Arch Endocrinol Metab. 2020 Feb;64(1):89–95.
   PubMed Web of Science ®Google Scholar
• Toloza FJK, Motahari H, Maraka S. Consequences of severe iodine deficiency in pregnancy: evidence in humans. Front Endocrinol (Lausanne). 2020;11:409.
   PubMedGoogle Scholar
• Laurberg P, Cerqueira C, Ovesen L, et al. Iodine intake as a determinant of thyroid disorders in populations. Best Pract Res Clin Endocrinol Metab. 2010 Feb;24(1):13–27.
   PubMed Web of Science ®Google Scholar
• de Escobar GM, Obregón MJ, Del Rey FE. Maternal thyroid hormones early in pregnancy and fetal brain development. Best Pract Res Clin Endocrinol Metab. 2004 Jun;18(2):225–248.
   PubMed Web of Science ®Google Scholar
• Soh SB, Aw TC. Laboratory testing in thyroid conditions - pitfalls and clinical utility. Ann Lab Med. 2019 Jan;39(1):3–14.
   PubMed Web of Science ®Google Scholar
• Iijima S. Pitfalls in the assessment of gestational transient thyrotoxicosis. Gynecol Endocrinol. 2020 Aug;36(8):662–667.
   PubMedGoogle Scholar
• Braunstein GD, Hershman JM. Comparison of serum pituitary thyrotropin and chorionic gonadotropin concentrations throughout pregnancy. J Clin Endocrinol Metab. 1976 Jun;42(6):1123–1126.
   PubMedGoogle Scholar
• Glinoer D, de Nayer P, Bourdoux P, et al. Regulation of maternal thyroid during pregnancy. J Clin Endocrinol Metab. 1990 Aug;71(2):276–287.
   PubMed Web of Science ®Google Scholar
• Lambert-Messerlian G, McClain M, Haddow JE, et al. First- and second-trimester thyroid hormone reference data in pregnant women: a FaSTER (First- and Second-Trimester Evaluation of Risk for aneuploidy) research consortium study. Am J Obstet Gynecol. 2008 Jul;199(1):62 e1–6.
   PubMed Web of Science ®Google Scholar
• Lee SY, Pearce EN. Testing, monitoring, and treatment of thyroid dysfunction in pregnancy. J Clin Endocrinol Metab. 2021 Mar 8;106(3):883–892.
   PubMed Web of Science ®Google Scholar
• Gronowski AM. Evaluation of thyroid function during pregnancy: have we taken a wrong turn? Clin Chem. 2018 Mar;64(3):439–441.
   PubMed Web of Science ®Google Scholar
• Soldin OP, Tractenberg RE, Hollowell JG, et al. Trimester-specific changes in maternal thyroid hormone, thyrotropin, and thyroglobulin concentrations during gestation: trends and associations across trimesters in iodine sufficiency. Thyroid. 2004 Dec;14(12):1084–1090.
   PubMedGoogle Scholar
• Visser WE, Peeters RP. Interpretation of thyroid function tests during pregnancy. Best Pract Res Clin Endocrinol Metab. 2020 Jul;34(4):101431.
   PubMed Web of Science ®Google Scholar
• Sapin R, d’Herbomez M. Free thyroxine measured by equilibrium dialysis and nine immunoassays in sera with various serum thyroxine-binding capacities. Clin Chem. 2003 Sep;49(9):1531–1535.
   PubMed Web of Science ®Google Scholar
• Lee RH, Spencer CA, Mestman JH, et al. Free T4 immunoassays are flawed during pregnancy. Am J Obstet Gynecol. 2009 Mar;200(3):260 e1–6.
   Web of Science ®Google Scholar
• Okosieme OE, Agrawal M, Usman D, et al. Method-dependent variation in TSH and FT4 reference intervals in pregnancy: a systematic review. Ann Clin Biochem. 2021 Sep;58(5):537–546.
   PubMed Web of Science ®Google Scholar
• Gilbert RM, Hadlow NC, Walsh JP, et al. Assessment of thyroid function during pregnancy: first-trimester (weeks 9-13) reference intervals derived from Western Australian women. Med J Aust. 2008 Sep 1;189(5):250–253.
   PubMedGoogle Scholar
• Vila L, Serra-Prat M, Palomera E, et al. Reference values for thyroid function tests in pregnant women living in Catalonia, Spain. Thyroid. 2010 Feb;20(2):221–225.
   PubMedGoogle Scholar
• Anckaert E, Poppe K, Van Uytfanghe K, et al. FT4 immunoassays may display a pattern during pregnancy similar to the equilibrium dialysis ID-LC/tandem MS candidate reference measurement procedure in spite of susceptibility towards binding protein alterations. Clin Chim Acta. 2010 Sep 6;411(17–18):1348–1353.
   PubMed Web of Science ®Google Scholar
• Chen Z, Yang X, Zhang C, et al. Thyroid function test abnormalities in twin pregnancies. Thyroid. 2021 Apr;31(4):572–579.
   PubMedGoogle Scholar
• Schulte S, Gohlke B, Schreiner F, et al. Thyroid function in monozygotic twins with intra-twin birth weight differences: a prospective longitudinal cohort study. J Pediatr. 2019 Aug;211:164–171 e4.
   PubMedGoogle Scholar
• Jiang YX, Sun WJ, Zhang Y, et al. Thyroid function of twin-pregnant women in early pregnancy. Chin Med J (Engl). 2019 Sep 5;132(17):2033–2038.
   PubMedGoogle Scholar
• Hanaoka M, Arata N, Sago H. Change of maternal thyroid function in twin-twin transfusion syndrome. Endocr J. 2015;62(10):949–952.
   PubMedGoogle Scholar
• Ashoor G, Muto O, Poon LC, et al. Maternal thyroid function at gestational weeks 11-13 in twin pregnancies. Thyroid. 2013 Sep;23(9):1165–1171.
   PubMedGoogle Scholar
• Haddow JE, Palomaki GE, McClain MR. Thyroid-stimulating hormone in singleton and twin pregnancy: importance of gestational age-specific reference ranges. Obstet Gynecol. 2006 Jan;107(1):205–206. author reply 206.
   PubMedGoogle Scholar
• Dashe JS, Casey BM, Wells CE, et al. Thyroid-stimulating hormone in singleton and twin pregnancy: importance of gestational age-specific reference ranges. Obstet Gynecol. 2005 Oct;106(4):753–757.
   PubMed Web of Science ®Google Scholar
• Mao J, Pop VJ, Bath SC, et al. Effect of low-dose selenium on thyroid autoimmunity and thyroid function in UK pregnant women with mild-to-moderate iodine deficiency. Eur J Nutr. 2016 Feb;55(1):55–61.
   PubMedGoogle Scholar
• Hofstee P, James-McAlpine J, McKeating DR, et al. Low serum selenium in pregnancy is associated with reduced T3 and increased risk of GDM. J Endocrinol. 2021 Jan;248(1):45–57.
   PubMedGoogle Scholar
• Guo X, Zhou L, Xu J, et al. Prenatal maternal low selenium, high thyrotropin, and low birth weights. Biol Trace Elem Res. 2021 Jan;199(1):18–25.
   PubMed Web of Science ®Google Scholar
• Arikan TA. Plasma selenium levels in first trimester pregnant women with hyperthyroidism and the relationship with thyroid hormone status. Biol Trace Elem Res. 2015 Oct;167(2):194–199.
   PubMedGoogle Scholar
• Winther KH, Rayman MP, Bonnema SJ, et al. Selenium in thyroid disorders - essential knowledge for clinicians. Nat Rev Endocrinol. 2020 Mar;16(3):165–176.
   PubMed Web of Science ®Google Scholar
• Berlin M, Barchel D, Brik A, et al. Maternal and newborn thyroid hormone, and the association with Polychlorinated Biphenyls (PCBs) Burden: the EHF (Environmental Health Fund) birth cohort. Front Pediatr. 2021;9:705395.
   PubMedGoogle Scholar
• Itoh S, Baba T, Yuasa M, et al. Association of maternal serum concentration of hydroxylated polychlorinated biphenyls with maternal and neonatal thyroid hormones: the Hokkaido birth cohort study. Environ Res. 2018 Nov;167:583–590.
   PubMedGoogle Scholar
• Hisada A, Shimodaira K, Okai T, et al. Associations between levels of hydroxylated PCBs and PCBs in serum of pregnant women and blood thyroid hormone levels and body size of neonates. Int J Hyg Environ Health. 2014 Apr-May;217(4–5):546–553.
   PubMed Web of Science ®Google Scholar
• El Majidi N, Bouchard M, Carrier G. Systematic analysis of the relationship between standardized biological levels of polychlorinated biphenyls and thyroid function in pregnant women and newborns. Chemosphere. 2014 Mar;98:1–17.
   PubMed Web of Science ®Google Scholar
• Berg V, Nøst TH, Pettersen RD, et al. Persistent organic pollutants and the association with maternal and infant thyroid homeostasis: a multipollutant assessment. Environ Health Perspect. 2017 Jan;125(1):127–133.
   PubMed Web of Science ®Google Scholar
• Ilias I, Kakoulidis I, and Togias S, et al. Atmospheric pollution and thyroid function of pregnant women in Athens, Greece: a pilot study. Med Sci (Basel). 2020 Apr 4;8(2):19.
   Google Scholar
• Ghassabian A, Pierotti L, Basterrechea M, et al. Association of exposure to ambient air pollution with thyroid function during pregnancy. JAMA Network Open. 2019 Oct 2;2(10):e1912902.
   PubMedGoogle Scholar
• Qiu L, Shen W, Ye C, et al. Association of exposure to PM(2.5)-bound metals with maternal thyroid function in early pregnancy. Sci Total Environ. 2021 Oct 23;810:151167.
   PubMedGoogle Scholar
• Zhao Y, Cao Z, Li H, et al. Air pollution exposure in association with maternal thyroid function during early pregnancy. J Hazard Mater. 2019 Apr 5;367:188–193.
   PubMedGoogle Scholar
• De Leo S, Pearce EN. Autoimmune thyroid disease during pregnancy. Lancet Diabetes Endocrinol. 2018 Jul;6(7):575–586.
   PubMed Web of Science ®Google Scholar
• Balucan FS, Morshed SA, Davies TF. Thyroid autoantibodies in pregnancy: their role, regulation and clinical relevance. J Thyroid Res. 2013;2013:182472.
   PubMedGoogle Scholar
• Willms A, Bieler D, Wieler H, et al. Correlation between sonography and antibody activity in patients with Hashimoto thyroiditis. J Ultrasound Med. 2013 Nov;32(11):1979–1986.
   PubMedGoogle Scholar
• Moleti M, Sturniolo G, Mauro MD, et al. Autoimmune thyroid diseases and pregnancy. Ann Thyroid. 2018 July;3(7):18.
   Google Scholar
• Piccinni MP, Raghupathy R, Saito S, et al. Cytokines, hormones and cellular regulatory mechanisms favoring successful reproduction. Front Immunol. 2021;12:717808.
   PubMed Web of Science ®Google Scholar
• Lazzarin N, Moretti C, De Felice G, et al. Further evidence on the role of thyroid autoimmunity in women with recurrent miscarriage. Int J Endocrinol. 2012;2012:717185.
   PubMed Web of Science ®Google Scholar
• Veltri F, Poppe K. Variables contributing to thyroid (Dys)function in pregnant women: more than thyroid antibodies? Eur Thyroid J. 2018 Jun;7(3):120–128.
   PubMedGoogle Scholar
• Lepez T, Vandewoestyne M, Deforce D. Fetal microchimeric cells in blood and thyroid glands of women with an autoimmune thyroid disease. Chimerism. 2012 Jan-Mar;3(1):21–23.
   PubMedGoogle Scholar
• Greer LG, Casey BM, Halvorson LM, et al. Antithyroid antibodies and parity: further evidence for microchimerism in autoimmune thyroid disease. Am J Obstet Gynecol. 2011 Nov;205(5):471 e1–4.
   Google Scholar
• Yehuda M, Wang CH, Pak Y, et al. Parity and risk of thyroid autoimmunity based on the NHANES (2001-2002, 2007-2008, 2009-2010, and 2011-2012). J Clin Endocrinol Metab. 2017 Sep 1;102(9):3437–3442.
   PubMedGoogle Scholar
• Negro R. Selenium and thyroid autoimmunity. Biologics. 2008 Jun;2(2):265–273.
   PubMedGoogle Scholar
• Hubalewska-Dydejczyk A, Duntas L, Gilis-Januszewska A. Pregnancy, thyroid, and the potential use of selenium. Hormones (Athens). 2020 Mar;19(1):47–53.
   PubMedGoogle Scholar
• Wang B, Xu Y, Hou X, et al. Small intestinal bacterial overgrowth in subclinical hypothyroidism of pregnant women. Front Endocrinol (Lausanne). 2021;12:604070.
   PubMedGoogle Scholar
• López-Muñoz E, Mateos-Sánchez L, Mejía-Terrazas GE, et al. Hypothyroidism and isolated hypothyroxinemia in pregnancy, from physiology to the clinic. Taiwan J Obstet Gynecol. 2019 Nov;58(6):757–763.
   PubMed Web of Science ®Google Scholar
• Sullivan SA. Hypothyroidism in Pregnancy. Clin Obstet Gynecol. 2019 Jun;62(2):308–319.
   PubMed Web of Science ®Google Scholar
• Teng W, Shan Z, Patil-Sisodia K, et al. Hypothyroidism in pregnancy. Lancet Diabetes Endocrinol. 2013 Nov;1(3):228–237.
   PubMed Web of Science ®Google Scholar
• Linardi A, Kakoulidis I, Ilias I, et al. Postpartum follow-up of women who developed subclinical hypothyroidism during pregnancy. Med Sci (Basel). 2020 Aug 3;8(3). DOI:https://doi.org/10.3390/medsci8030029.
   Google Scholar
• Cooper DS, Laurberg P. Hyperthyroidism in pregnancy. Lancet Diabetes Endocrinol. 2013 Nov;1(3):238–249.
   PubMed Web of Science ®Google Scholar
• Yalamanchi S, Cooper DS. Thyroid disorders in pregnancy. Curr Opin Obstet Gynecol. 2015 Dec;27(6):406–415.
   PubMedGoogle Scholar
• Bucci I, Giuliani C, Napolitano G. Thyroid-stimulating hormone receptor antibodies in pregnancy: clinical relevance. Front Endocrinol (Lausanne). 2017;8:137.
   PubMed Web of Science ®Google Scholar
• Andersen SL, Andersen S. Antithyroid drugs and birth defects. Thyroid Res. 2020;13(1):11.
   PubMedGoogle Scholar
• Andersen SL, Knøsgaard L. Management of thyrotoxicosis during pregnancy. Best Pract Res Clin Endocrinol Metab. 2020 Jul;34(4):101414.
   PubMed Web of Science ®Google Scholar
• Dumitrascu MC, Nenciu AE, Florica S, et al. Hyperthyroidism management during pregnancy and lactation (Review). Exp Ther Med. 2021 Sep;22(3):960.
   PubMed Web of Science ®Google Scholar
• Francis T, Francis N, Lazarus JH, et al. Safety of antithyroid drugs in pregnancy: update and therapy implications. Expert Opin Drug Saf. 2020 May;19(5):565–576.
   PubMed Web of Science ®Google Scholar
• Brancatella A, Viola N, Rutigliano G, et al. Subacute thyroiditis during the SARS-CoV-2 pandemic. J Endocr Soc. 2021 Oct 1;5(10):bvab130.
   PubMedGoogle Scholar
• Muller I, Cannavaro D, Dazzi D, et al. SARS-CoV-2-related atypical thyroiditis. Lancet Diabetes Endocrinol. 2020 Sep;8(9):739–741.
   PubMed Web of Science ®Google Scholar
• Pirola I, Gandossi E, Rotondi M, et al. Incidence of De Quervain’s thyroiditis during the COVID-19 pandemic in an area heavily affected by Sars-CoV-2 infection. Endocrine. 2021 Nov;74(2):215–218.
   PubMedGoogle Scholar
• Vassiliadi DA, Ilias I, Pratikaki M, et al. Thyroid hormone alterations in critically and non-critically ill patients with SARS-CoV-2 infection. Endocr Connect. 2021 Jun 17;10(6):646–655.
   PubMed Web of Science ®Google Scholar
• Sciacchitano S, Capalbo C, Napoli C, et al. Nonthyroidal illness syndrome (NTIS) in severe COVID-19 patients: role of T3 on the Na/K pump gene expression and on hydroelectrolytic equilibrium. J Transl Med. 2021 Dec 3;19(1):491.
   PubMedGoogle Scholar
• Poma AM, Bonuccelli D, Giannini R, et al. COVID-19 autopsy cases: detection of virus in endocrine tissues. J Endocrinol Invest. 2021;30:1–6.
   Google Scholar
• Hua J, Shen J, Zhang J, et al. The association between COVID-19 pandemic and maternal isolated hypothyroxinemia in first and second trimesters. Psychoneuroendocrinology. 2021 Jun;128:105210.
   PubMed Web of Science ®Google Scholar
• Lin TT, Zhang C, Zhang HQ, et al. Thyroid hormone changes in early pregnancy along with the COVID-19 pandemic. Front Endocrinol (Lausanne). 2020;11:606723.
   PubMedGoogle Scholar
• Clarke SA, Abbara A, Dhillo WS. Impact of COVID-19 on the endocrine system: a mini-review. Endocrinology. 2022 Jan 1;163(1). DOI:https://doi.org/10.1210/endocr/bqab203.
   Web of Science ®Google Scholar
• Shi Q, Wu M, Chen P, et al. Criminal of adverse pregnant outcomes: a perspective from thyroid hormone disturbance caused by SARS-CoV-2. Front Cell Infect Microbiol. 2021;11:791654.
   PubMedGoogle Scholar
• Leung AM. Thyroid function in pregnancy. J Trace Elem Med Biol. 2012 Jun;26(2–3):137–140.
   PubMed Web of Science ®Google Scholar
• Cortés-Albornoz MC, García-Guáqueta DP, Velez-van-Meerbeke A, et al. Maternal nutrition and neurodevelopment: a scoping review. Nutrients. 2021;13(10):3530.
   PubMed Web of Science ®Google Scholar
• Lee SY, Pearce EN. Preconception care to optimize pregnancy outcomes. JAMA. 2021;326(21):2204–2205.
   PubMedGoogle Scholar
• Zimmermann MB. The effects of iodine deficiency in pregnancy and infancy. Paediatr Perinat Epidemiol. 2012 Jul;26(1):108–117.
   PubMedGoogle Scholar
• Carney LA, Quinlan JD, West JM. Thyroid disease in pregnancy. Am Fam Physician. 2014 Feb 15;89(4):273–278.
   PubMed Web of Science ®Google Scholar
• Korevaar TIM, Medici M, Visser TJ, et al. Thyroid disease in pregnancy: new insights in diagnosis and clinical management. Nat Rev Endocrinol. 2017 Oct;13(10):610–622.
   PubMed Web of Science ®Google Scholar
• Medici M, Korevaar TI, Visser WE, et al. Thyroid function in pregnancy: what is normal? Clin Chem. 2015 May;61(5):704–713.
   PubMed Web of Science ®Google Scholar
• Casey BM, Leveno KJ. Thyroid disease in pregnancy. Obstet Gynecol. 2006 Nov;108(5):1283–1292.
   PubMedGoogle Scholar
• van Dijk MM, Smits IH, Fliers E, et al. Maternal thyrotropin receptor antibody concentration and the risk of fetal and neonatal thyrotoxicosis: a systematic review. Thyroid. 2018 Feb;28(2):257–264.
   PubMed Web of Science ®Google Scholar