References
- Levetin E, Horner WE, Scott JA, et al. Taxonomy of allergenic fungi. J Allergy Clin Immunol Pract. 2016;4(3):375–85 e1. .
- Chen J, Seviour R. Medicinal importance of fungal beta-(1–>3), (1–>6)-glucans. Mycol Res. 2007;111(Pt 6):635–652.
- Taylor J, Jacobson D, Fisher M. THE EVOLUTION OF ASEXUAL FUNGI: reproduction, speciation and classification. Annu Rev Phytopathol. 1999;37:197–246.
- Portnoy J, Barnes C. The National Allergy Bureau: pollen and spore reporting today. J Allergy Clin Immunol. 2004;114(5):1235–1238.
- Dales RE, Cakmak S, Judek S, et al. The role of fungal spores in thunderstorm asthma. Chest. 2003;123(3):745–750.
- D’Amato G, Vitale C, D’Amato M, et al. Thunderstorm-related asthma: what happens and why. Clin Exp Allergy. 2016;46(3):390–396.
- Flannigan B, Miller J. Microbial growth in indoor environments. In: Flannigan B, Samson R, Miller J, editors. Microorganisms in home and indoor work environments: diversity, health impacts, investigation and control. 2nd ed. New York: Taylor & Francis; 2011. p. 57–107.
- Park JH, Cox-Ganser JM. Mold exposure and respiratory health in damp indoor environments. Front Bioscience. 2011;3:757–771.
- Dales RE, Burnett R, Zwanenburg H. Adverse health effects among adults exposed to home dampness and molds. Am Rev Respir Dis. 1991;143(3):505–509.
- Portnoy J, Flappan S, Barnes C. A procedure for evaluation of the indoor environment. Aerobiologia (Bologna). 2001;17(1):43–48.
- Baxi SN, Portnoy JM, Larenas-Linnemann D, et al. Exposure and health effects of fungi on humans. J Allergy Clin Immunol Pract. 2016;4(3):396–404.
- Barnes CS, Horner WE, Kennedy K, et al. Home assessment and remediation. J Allergy Clin Immunol Pract. 2016;4(3):423–31.e15.
- Williams PB, Barnes CS, Portnoy JM, et al. Innate and adaptive immune response to fungal products and allergens. J Allergy Clin Immunol Pract. 2016;4(3):386–395.
- Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system. Science (80-). 2002;296(5566):298–300.
- Zheng N-X, Wang Y, Hu -D-D, et al. The role of pattern recognition receptors in the innate recognition of Candida albicans. Virulence. 2015;6(4):347–361.
- Plato A, Hardison SE, Brown GD. Pattern recognition receptors in antifungal immunity. Semin Immunopathol. 2015;37(2):97–106.
- Matzinger P. The danger model: a renewed sense of self. Science. 2002;296(5566):301–305.
- Tang D, Kang R, Coyne CB, et al. PAMPs and DAMPs: signal 0s that spur autophagy and immunity. Immunol Rev. 2012;249(1):158–175.
- Land WG. The role of Damage-Associated Molecular Patterns (DAMPs) in human diseases: part II: DAMPs as diagnostics, prognostics and therapeutics in clinical medicine. Sultan Qaboos Univ Med J. 2015;15(2):e157–70.
- Chew GL, Horner WE, Kennedy K, et al. Procedures to assist health care providers to determine when home assessments for potential mold exposure are warranted. J Allergy Clin Immunol Pract. 2016;4(3):417–22.e2.
- Reed CE, Kita H, The role of protease activation of inflammation in allergic respiratory diseases. J Allergy Clin Immunol. 2004;114(5):997–1008. quiz 9.
- Weinberger EE, Isakovic A, Scheiblhofer S, et al. The influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine. Vaccine. 2013;31(51):6113–6121.
- Wang L-F, Chen J-S, Hsu C-J, et al. Antigen-driven bystander effect accelerates epicutaneous sensitization with a new protein allergen. J Biomed Sci. 2009;16:28.
- Pichler U, Hauser M, Wolf M, et al. Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern. Plos One. 2015;10(5):e0120038.
- Twaroch TE, Curin M, Valenta R, et al. Mold allergens in respiratory allergy: from structure to therapy. Allergy Asthma Immunol Res. 2015;7(3):205–220.
- Bowyer P, Fraczek M, Denning DW. Comparative genomics of fungal allergens and epitopes shows widespread distribution of closely related allergen and epitope orthologues. BMC Genomics. 2006;7:251.
- Soeria-Atmadja D, Onell A, Borgå A. IgE sensitization to fungi mirrors fungal phylogenetic systematics. J Allergy Clin Immunol. 2010;125(6):1379–86.e1.
- Sáenz-de-Santamaría M, Postigo I, Gutierrez-Rodríguez A, et al. The major allergen of Alternaria alternata (Alt a 1) is expressed in other members of the Pleosporaceae family. Mycoses. 2006;49(2):91–95.
- Andersson M, Downs S, Mitakakis T, et al. Natural exposure to Alternaria spores induces allergic rhinitis symptoms in sensitized children. Pediatr Allergy Immunol. 2003;14(2):100–105.
- Schultze-Werninghaus G, Lévy J, Bergmann EM, et al. Clinical significance of airborne Alternaria tenuis-spores: seasonal symptoms, positive skin and bronchial challenge tests with Alternaria in subjects with asthma and rhinitis. Experientia Suppl. 1987;51:153–156.
- Karvonen AM, Hyvärinen A, Korppi M, et al. Moisture damage and asthma: a birth cohort study. Pediatrics. 2015;135(3):e598–606.
- Fisk WJ, Lei-Gomez Q, Mendell MJ. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air. 2007;17(4):284–296.
- Mendell MJ, Mirer AG, Cheung K, et al. Respiratory and allergic health effects of dampness, mold, and dampness-related agents: a review of the epidemiologic evidence. Environ Health Perspect. 2011;119(6):748–756.
- Quansah R, Jaakkola MS, Hugg TT, et al. Residential dampness and molds and the risk of developing asthma: a systematic review and meta-analysis. Plos One. 2012;7(11):e47526.
- Sauni R, Verbeek JH, Uitti J, et al. Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma. Cochrane Database Syst Rev. 2015;2:CD007897.
- Kercsmar CM, Dearborn DG, Schluchter M, et al. Reduction in asthma morbidity in children as a result of home remediation aimed at moisture sources. Environ Health Perspect. 2006;114(10):1574–1580.
- Williams PB, Ahlstedt S, Barnes JH, et al. Are our impressions of allergy test performances correct? Ann Allergy Asthma Immunol. 2003;91(1):26–33.
- Esch RE. Manufacturing and standardizing fungal allergen products. J Allergy Clin Immunol. 2004;113(2):210–215.
- Portnoy J, Pacheco F, Ballam Y, et al. The effect of time and extraction buffers on residual protein and allergen content of extracts derived from four strains of Alternaria. J Allergy Clin Immunol. 1993;91(4):930–938.
- Portnoy JM, Jara D. Mold allergy revisited. Ann Allergy, Asthma Immunol. 2015;114(2):83–89.
- Mari A, Schneider P, Wally V, et al. Sensitization to fungi: epidemiology, comparative skin tests, and IgE reactivity of fungal extracts. Clin Exp Allergy. 2003;33(10):1429–1438.
- Scala E, Alessandri C, Bernardi ML, et al. Cross-sectional survey on immunoglobulin E reactivity in 23,077 subjects using an allergenic molecule-based microarray detection system. Clin Exp Allergy. 2010;40(6):911–921.
- Korppi M, Laitinen S, Taskinen T, et al. Mold-specific immunoglobulin G antibodies in a child population. Pediatr Allergy Immunol. 2003;14(5):371–377.
- Jaakkola MS, Laitinen S, Piipari R, et al. Immunoglobulin G antibodies against indoor dampness-related microbes and adult-onset asthma: a population-based incident case-control study. Clin Exp Immunol. 2002;129(1):107–112.
- Rydjord B, Hetland G, Wiker HG. Immunoglobulin G antibodies against environmental moulds in a Norwegian healthy population shows a bimodal distribution for Aspergillus versicolor. Scand J Immunol. 2005;62(3):281–288.
- Vojdani A, Campbell AW, Kashanian A, et al. Antibodies against molds and mycotoxins following exposure to toxigenic fungi in a water-damaged building. Arch Environ Health. 2003;58(6):324–336.
- Cortellini G, Spadolini I, Patella V, et al. Sublingual immunotherapy for Alternaria-induced allergic rhinitis: a randomized placebo-controlled trial. Ann Allergy Asthma Immunol. 2010;105(5):382–386.
- Kuna P, Kaczmarek J, Kupczyk M. Efficacy and safety of immunotherapy for allergies to Alternaria alternata in children. J Allergy Clin Immunol. 2011;127(2):502–506.
- Horst M, Hejjaoui A, Horst V, et al. Double-blind, placebo-controlled rush immunotherapy with a standardized Alternaria extract. J Allergy Clin Immunol. 1990;85(2):460–472.
- Nelson B Stachybotrys chartarum: the toxic indoor mold St. Paul, MN: The American Phytopathological Siciety; 1999. [Nov 28, 2016]. Available from: http://www.apsnet.org/publications/apsnetfeatures/Pages/Stachybotrys.aspx.
- Schneider DJ, Marasas WF, Dale Kuys JC, et al. A field outbreak of suspected stachybotryotoxicosis in sheep. J S Afr Vet Assoc. 1979;50(2):73–81.
- Miller JD, Rand TG, Jarvis BB. Stachybotrys chartarum: cause of human disease or media darling? Med Mycol. 2003;41(4):271–291.
- Johanning E, Biagini R, Hull D, et al. Health and immunology study following exposure to toxigenic fungi (Stachybotrys chartarum) in a water-damaged office environment. Int Arch Occup Environ Health. 1996;68(4):207–218.
- Dearborn DG, Smith PG, Dahms BB, et al. Clinical profile of 30 infants with acute pulmonary hemorrhage in Cleveland. Pediatrics. 2002;110(3):627–637.
- Centers for Disease C, Prevention. Update: pulmonary hemorrhage/hemosiderosis among infants–Cleveland, Ohio, 1993-1996. MMWR Morb Mortal Wkly Rep. 2000;49(9):180–184.
- Centers for Disease C, Prevention. Update: pulmonary hemorrhage/hemosiderosis among infants–Cleveland, Ohio, 1993-1996. MMWR Morb Mortal Wkly Rep. 1997;46(2):33–35.
- Jarvis BB, Miller JD. Mycotoxins as harmful indoor air contaminants. Appl Microbiol Biotechnol. 2005;66(4):367–372.
- Dales R, Raizenne M. Residential exposure to volatile organic compounds and asthma. J Asthma. 2004;41(3):259–270.
- Belkin L Haunted by Mold: the New York Times magazine; August 12, 2001 [November 21, 2016]. Available from: http://www.nytimes.com/2001/08/12/magazine/haunted-by-mold.html?pagewanted=all&src=pm.
- Portnoy JM, Kennedy K, Barnes CS. Controversies regarding dampness and mold growth in homes. Allergy Asthma Proc. 2007;28(3):257–258.
- Terr AI. Stachybotrys: relevance to human disease. Ann Allergy Asthma Immunol. 2001;87(Suppl 6):57–63.
- Chapman JA, Terr AI, Jacobs RL, et al. Toxic mold: phantom risk vs science. Ann Allergy Asthma Immunol. 2003;91(3):222–232.
- Auger PL, Gourdeau P, Miller JD. Clinical experience with patients suffering from a chronic fatigue-like syndrome and repeated upper respiratory infections in relation to airborne molds. Am J Ind Med. 1994;25(1):41–42.
- Brown CM, Redd SC, Damon SA. Centers for Disease C, prevention. Acute idiopathic pulmonary hemorrhage among infants. Recommendations from the working group for investigation and surveillance. MMWR Recomm Rep. 2004;53(RR–2):1–12.
- Bush RK, Portnoy JM, Saxon A, et al. The medical effects of mold exposure. J Allergy Clin Immunol. 2006;117(2):326–333.
- Committee on Environmental Health. Toxic effects of indoor molds. American Academy of Pediatrics. Pediatrics. 1998;101(4 Pt 1):712–714.
- Hardin BD, Kelman BJ, Saxon A. Adverse human health effects associated with molds in the indoor environment. J Occup Environ Med. 2003;45(5):470–478.
- Craner J. A critique of the ACOEM statement on mold: undisclosed conflicts of interest in the creation of an “evidence-based” statement. Int J Occup Environ Health. 2008;14(4):283–298.
- Edmondson DA, Nordness ME, Zacharisen MC, et al. Allergy and “toxic mold syndrome”. Ann Allergy Asthma Immunol. 2005;94(2):234–239.
- Al-Ahmad M, Manno M, Ng V, et al. Symptoms after mould exposure including Stachybotrys chartarum, and comparison with darkroom disease. Allergy. 2010;65(2):245–255.
- Terr AI. Are indoor molds causing a new disease? J Allergy Clin Immunol. 2004;113(2):221–226.
- WHO guidelines for indoor air quality: dampnessand mould. Copenhagen, Denmark: World Health Organization; 2009. .
- Nielsen K, Hansen M, Larsen T, et al. Production of trichothecene mycotoxins on water damaged gypsum boards in Danish buildings. Int Biodeterior Biodegradation. 1998;42:1–7.
- Vesper S, Dearborn DG, Yike I, et al. Evaluation of Stachybotrys chartarum in the house of an infant with pulmonary hemorrhage: quantitative assessment before, during, and after remediation. J Urban Health. 2000;77(1):68–85.
- De La Campa R, Seifert K, Miller JD. Toxins from strains of Penicillium chrysogenum isolated from buildings and other sources. Mycopathologia. 2007;163(3):161–168.
- Houbraken J, Frisvad JC, Samson RA. Fleming’s penicillin producing strain is not Penicillium chrysogenum but P. rubens. Rubens. IMA Fungus. 2011;2(1):87–95.
- Nielsen KF, Gravesen S, Nielsen PA, et al. Production of mycotoxins on artificially and naturally infested building materials. Mycopathologia. 1999;145(1):43–56.
- Bloom E, Nyman E, Must A, et al. Molds and mycotoxins in indoor environments–a survey in water-damaged buildings. J Occup Environ Hyg. 2009;6(11):671–678.
- Jarvis BB. Analysis for mycotoxins: the chemist’s perspective. Arch Environ Health. 2003;58(8):479–483.
- Nielsen K, Holm G, Uttrup L, et al. Mould growth on building materials under low water activities . Influence Humidity Temperature Fungal Growth Secondary Metabolism Int Biodeterior Biodegradation. 2004;54(4):325–336.
- Tuomi T, Reijula K, Johnsson T, et al. Mycotoxins in crude building materials from water-damaged buildings. Appl Environ Microbiol. 2000;66(5):1899–1904.
- Engelhart S, Loock A, Skutlarek D, et al. Occurrence of toxigenic Aspergillus versicolor isolates and sterigmatocystin in carpet dust from damp indoor environments. Appl Environ Microbiol. 2002;68(8):3886–3890.
- Slack GJ, Puniani E, Frisvad JC, et al. Secondary metabolites from Eurotium species, Aspergillus calidoustus and A. insuetus common in Canadian homes with a review of their chemistry and biological activities. Mycol Res. 2009;113(Pt 4):480–490.
- McMullen DRSM, Miller JD. Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment. Mycotoxin Res. 2012;29:47–54.
- Taubel M, Sulyok M, Vishwanath V, et al. Co-occurrence of toxic bacterial and fungal secondary metabolites in moisture-damaged indoor environments. Indoor Air. 2011;21(5):368–375.
- Nielsen K, Frisvad J. Mycotoxins on building materials. In: Adan OCG, Samson RA, editors. Fundamentals of mold growth in indoor environments and strategies for healthy living. Wageningen Academic Publishers; 2011. p. 245–275. ISBN: 978-90-8686-722-6.
- Wu Q, Dohnal V, Huang L, et al. Metabolic pathways of trichothecenes. Drug Metab Rev. 2010;42(2):250–267.
- Barel S, Yagen B, Bialer M. Pharmacokinetic profile of conjugated verrucarol urinary metabolites in dogs. Biopharm Drug Dispos. 1994;15(7):609–616.
- Van Emon JM, Reed AW, Yike I, et al. ELISA measurement of stachylysin in serum to quantify human exposures to the indoor mold Stachybotrys chartarum. J Occup Environ Med. 2003;45(6):582–591.
- Seifert SA, Von Essen S, Jacobitz K, et al. Organic dust toxic syndrome: a review. J Toxicol Clin Toxicol. 2003;41(2):185–193.
- Nielsen K. Mould growth on building materials [ PhD Thesis]. Lyngby, Denmark: Technical University of Denmark; 2002.
- Kawamoto M, Page E, Centers for Disease C, Prevention. Notes from the field: use of unvalidated urine mycotoxin tests for the clinical diagnosis of illness–United States, 2014. MMWR Morb Mortal Wkly Rep. 2015;64(6):157–158.
- Ahn J, Kim D, Kim H, et al. Quantitative determination of mycotoxins in urine by LC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010;27(12):1674–1682.
- Duarte SC, Pena A, Lino CM. Human ochratoxin a biomarkers–from exposure to effect. Crit Rev Toxicol. 2011;41(3):187–212.