Genetic variations in the human immune system influence susceptibility to tegumentary leishmaniasis: a systematic review and meta-analysis

References

• World Health Organization. Leishmaniasis. 2020. [cited 2020 Oct 7]. Available from: https://www.who.int/health-topics/leishmaniasis#tab=tab_1
   Google Scholar
• Martinez DY, Verdonck K, Kaye PM, et al. Tegumentary leishmaniasis and coinfections other than HIV. PLoS Negl Trop Dis. 2018;12(3):1–20.
   Web of Science ®Google Scholar
• Oyama J, Ferreira FBP, Conter CC, et al. American tegumentary leishmaniasis: diagnostic and treatment challenges in a clinical case Jully. Rev Inst Med Trop Sao Paulo. 2018;60(3):1–4.
   Google Scholar
• Lindoso JAL, Costa JML, Queiroz IT, et al. Review of the current treatments for leishmaniases. Res Rep Trop Med. 2012;3:69–77.
   PubMedGoogle Scholar
• Scott P, Novais FO. Cutaneous leishmaniasis: immune responses in protection and pathogenesis. Nat Rev Immunol. 2016;16:581–592.
   PubMed Web of Science ®Google Scholar
• Mirzaei A, Maleki M, Masoumi E, et al. A historical review of the role of cytokines involved in leishmaniasis. Cytokine 2020;155297. doi:10.1016/j.cyto.2020.155297.
   PubMedGoogle Scholar
• Samaranayake N, Fernando SD, Neththikumara NF, et al. Association of HLA class I and II genes with cutaneous leishmaniasis : a case control study from Sri Lanka and a systematic review. BMC Infect Dis. 2016;1–9. DOI:10.1186/s12879-015-1330-0
   PubMed Web of Science ®Google Scholar
• Klebanov N. Genetic Predisposition to Infectious Disease. Cureus 2018;10:1–8.
   Web of Science ®Google Scholar
• Moher D, Liberati A, Tetzlaff J, et al. Preferred Reporting Items for Systematic Reviews and Meta-Analyses : the PRISMA Statement. PLOS Med. 2009;6:1-6.
   Web of Science ®Google Scholar
• Little J, Higgins JPT, Ioannidis JPA, et al. STrengthening the REporting of Genetic Association Studies (STREGA)— an Extension of the STROBE Statement. PLOS Med. 2009;6:151–163.
   Web of Science ®Google Scholar
• Schünemann H, Guyatt G, Oxman A, editors. GRADE Handbook for grading quality of evidence and strength of recommendations. Updated October 2013. The GRADE Working Group, 2013. Available from: http://guidelinedevelopment.org/handbook
   Google Scholar
• Santos FJA, Da Silva LS, Junior JES, et al. Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V .) guyanensis in Manaus, Amazonas, Brazil. PLoS One. 2019;14:1–10.
   Web of Science ®Google Scholar
• De Albuquerque SCG, Oliveira CNDC, Vaitkevicius-antão V, et al. Study of association of the rs2275913 IL-17A single nucleotide polymorphism and susceptibility to cutaneous leishmaniasis caused by Leishmania braziliensis. Cytokine. 2019;123:1-8.
   Web of Science ®Google Scholar
• Cabrera M, Shaw M-A, Sharpies C, et al. Polymorphism in Tumor Necrosis Factor Genes Associated with Mucocutaneous Leishmaniasis. J Exp Med. 1995;182:1259–1264.
   PubMed Web of Science ®Google Scholar
• Ajdary S, Ghamilouie M, Alimohammadian MH, et al. Lack of association of Toll-like receptor 2 Arg753Gln with cutaneous leishmaniasis. Parasitol Int. 2010;59:466–468.
   PubMed Web of Science ®Google Scholar
• Oliveira CR, Pereira LIA, Pereira ACS, et al. Allelic polymorphism of human Fc c RIIA-H ⁄ R131 receptor in American tegumentary leishmaniasis. Int J Immunogenet. 2011;38:225–231.
   PubMed Web of Science ®Google Scholar
• Da Silva GAV, De Mesquita TGR, Encarnação HVS, et al. A polymorphism in the IL1B gene (rs16944 T/C) is associated with cutaneous leishmaniasis caused by Leishmania guyanensis and plasma cytokine interleukin receptor antagonist. Cytokine 2019 123. doi:10.1016/j.cyto.2019.154788
   Web of Science ®Google Scholar
• Fernández-Figueroa EA, Rangel-Escareno C, Espinosa-Mateos V, et al. Disease Severity in Patients Infected with Leishmania mexicana Relates to IL-1 b. PLoS Negl Trop Dis 2012 6. doi:10.1371/journal.pntd.0001533
   Web of Science ®Google Scholar
• Oliveira PRS, Dessein H, Romano A, et al. IL2RA Genetic Variants Reduce IL-2 − Dependent Responses and Aggravate Human Cutaneous Leishmaniasis. J Immunol. 2015 Mar;194(6):2664–2672.
   PubMed Web of Science ®Google Scholar
• Kamali-sarvestani E, Rasouli M, Mortazavi H, et al. Cytokine gene polymorphisms and susceptibility to cutaneous leishmaniasis in Iranian patients. Cytokine. 2006;35:159–165.
   PubMed Web of Science ®Google Scholar
• Rafizadeh S, Saraei M, Abai M, et al. Relationship between interleukin 4 gene promoter polymorphisms and cutaneous Leishmaniasis cases in North Eastern Iran. Med Commun. 2016;9:415–420.
   Google Scholar
• Castellucci L, Menezes E, Oliveira J, et al. IL6 Ϫ 174 G/C Promoter Polymorphism Influences Susceptibility to Mucosal but Not Localized Cutaneous Leishmaniasis in Brazil Control subjects. J Infect Dis. 2006;194:519–527.
   PubMed Web of Science ®Google Scholar
• Shehadeh FVB, Dos Santos RR, Da Silva LAD, et al. TGF-β1 polymorphism in American tegumentary leishmaniasis in a Southern Brazilian population. J Brazilian Soc Trop Med. 2019;52:1–5.
   Web of Science ®Google Scholar
• Salhi A, Rodrigues V, Santoro F, et al. Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis. J Immunol. 2008 May;180(9):6139–6148. .
   PubMed Web of Science ®Google Scholar
• Covas CDJF, Cardoso CC, Gomes-silva A, et al. Candidate gene case-control and functional study shows macrophage inhibitory factor (MIF) polymorphism is associated with cutaneous leishmaniasis. Cytokine. 2013;61:168–172.
   PubMed Web of Science ®Google Scholar
• Mera-Ramírez A, Castillo A, Orobio Y, et al. Screening of TNF α, IL-10 and TLR4 single nucleotide polymorphisms in individuals with asymptomatic and chronic cutaneous leishmaniasis in Colombia : a pilot study. BMC Infect Dis. 2017;17:1–6.
   PubMed Web of Science ®Google Scholar
• Castellucci L, Jamieson SE, Almeida L, et al. Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil. Infect Genet Evol. 2012;12:1102–1110.
   PubMed Web of Science ®Google Scholar
• Ortiz-flores A, De Rosa-lópez G, Zavaleta-Villa B, et al. Association of leishmaniasis with TNF alpha promoter and SLC11A1 gene polymorphisms in patients of two endemic areas in Mexico. Microbes Infect. 2015;17:387-394.
   PubMed Web of Science ®Google Scholar
• Samaranayake N, Fernando D, Dissanayake VHW. Candidate gene study of susceptibility to cutaneous leishmaniasis in Sri Lanka Candidate gene study of susceptibility to cutaneous leishmaniasis in Sri Lanka. Trop Med Int Heal. 2010;15:632–638.
   PubMed Web of Science ®Google Scholar
• Matos GI, Covas CDJF, Brittar RDC, et al. IFNG + 874T/A polymorphism is not associated with American tegumentary leishmaniasis susceptibility but can influence Leishmania induced IFN- γ production. BMC Infect Dis. 2007;7:1–6.
   Web of Science ®Google Scholar
• Khudhur HR, Alomashi GB. MIF-173G > C Polymorphism and Susceptibility to Cutaneous Leishmaniasis in Iraq. Nano Biomed Eng. 2018;10:213–216.
   Google Scholar
• Ramasawmy R, Menezesa E, Magalha A, et al. The −2518 bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil. Infect Genet Evol J. 2010;10:607–613.
   PubMed Web of Science ®Google Scholar
• Castellucci L, Jamieson SE, Miller EN, et al. CXCR1 and SLC11A1 polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study. BMC Med Genet. 2010;11:1–8.
   PubMed Web of Science ®Google Scholar
• De Oliveira KB, Reiche EMV, Morimoto HK, et al. Analysis of the CC chemokine receptor 5 delta32 polymorphism in a Brazilian population with cutaneous leishmaniasis. J Cutan Pathol. 2007;34:27–32.
   PubMed Web of Science ®Google Scholar
• Sophie M, Muneer A, Samdani AJ. CC chemokine receptor 5 Δ 32 polymorphism : association analysis and allele distribution among cutaneous leishmaniasis patients from Pakistan. J Cutan Pathol. 2016;43:564–570.
   PubMed Web of Science ®Google Scholar
• Ajdary S, Ghamilouie M, Alimohammadian M, et al. Toll-like receptor 4 polymorphisms predispose to cutaneous leishmaniasis. Microbes Infect. 2011;13:226–231.
   PubMed Web of Science ®Google Scholar
• De Araujo FJ, Da Silva LDO, Mesquita TG, et al. Polymorphisms in the TOLLIP Gene Influence Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis in the Amazonas State of Brazil. PLoS Negl Trop Dis. 2015;9:1–10.
   Google Scholar
• De Araujo FJ, Mesquita TG, Da Silva LDO, et al. Functional variations in MBL2 gene are associated with cutaneous leishmaniasis in the Amazonas state of Brazil. Genes Immun. 2015;16:284–288.
   PubMed Web of Science ®Google Scholar
• Assaf A, Van HT, Faik I, et al. Genetic Evidence of Functional Ficolin-2 Haplotype as Susceptibility Factor in Cutaneous Leishmaniasis. PLoS One. 2012;7:1–7.
   Web of Science ®Google Scholar
• Fernândez-Mestre M, Sânchez K, Balbâs O, et al. Influence of CTLA-4 gene polymorphism in autoimmune and infectious diseases. Hum Immunol. 2009;70:532–535.
   PubMed Web of Science ®Google Scholar
• Molli AEI, Bergonzi MF, Spalvieri MP, et al. Relationship between the IL-1 β serum concentration, mRNA levels and rs16944 genotype in the hyperglycemic normalization of T2D patients. Sci Rep. 2020;1–9. doi:10.1038/s41598-019-56847-4
   PubMed Web of Science ®Google Scholar
• Cui G, Wang H, Li R, et al. Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke. J Neuroinflammation. 2012;9:1–11.
   PubMed Web of Science ®Google Scholar
• Crawford DC, Nickerson DA. Definition and clinical importance of haplotypes. Annu Rev Med. 2005;56:302–320.
   Web of Science ®Google Scholar
• Ranganathan P, Aggarwal R. Study designs : part 3 - Analytical observational studies. Perspect Clin Res. 2019;10(2):91–94.
   PubMedGoogle Scholar
• Aggarwal R, Ranganathan P. Study designs : part 4 – interventional studies. Perspect Clin Res. 2019;10(3):137–139.
   PubMedGoogle Scholar