28
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

Effect of exposure to dietary nivalenol on activity of enzymes involved in glutamine catabolism in the epithelium along the gastrointestinal tract of growing pigs

, &
Pages 275-284 | Received 29 Oct 1998, Published online: 10 Jan 2009

References

  • Ardawi , M. S. M. and Newsholme , E. A. 1985 . Fuel utilization in colonocytes of the rat . Biochem. J. , 231 : 565 – 572 .
  • Ardawi , M. S. M. 1988 . Glutamine and ketone‐body metabolism in the gut of streptozotocin‐diabetic rats . Biochem. J. , 249 : 565 – 572 .
  • Bergmeyer , H. U. and Bernt , E. 1974 . “ Glutamate‐pyruvate transaminase, UV‐assay, manual method ” . In Methods of Enzymatic Analysis. , 2nd edn. , Edited by: Bergmeyer , H.‐U. Vol. 2 , 752 – 758 . London and New York : Academic Press .
  • Bernt , E. and Bergmeyer , H. U. 1974a . “ L‐Glutamate, UV‐assay with glutamate dehydrogenase and NAD ” . In Methods of Enzymatic Analysis. , 2nd edn. , Edited by: Bergmeyer , H.‐U. Vol. 4 , 1704 – 1708 . London and New York : Academic Press .
  • Bernt , E. and Bergmeyer , H. U. 1974b . “ Isocitrate dehydrogenase, UV‐assay ” . In Methods of Enzymatic Analysis. , 2nd edn. , Edited by: Bergmeyer , H.‐U. Vol. 2 , 624 – 627 . London and New York : Academic Press .
  • Board , M. , Humm , S. and Newsholme , E. A. 1990 . Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells . Biochem. J. , 265 : 503 – 509 .
  • Brandtzaeg , P. , Bjerke , K. , Kett , K. , Kvale , D. , Rognum , T. O. , Scott , H. , Sollid , L. M. and Vaines , K. 1987 . Production and secretion of immunoglobulins in the gastrointestinal tract . Ann. Allergy. , 59 (5) : 21 – 39 .
  • Budohoski , L. , Challis , R. A. J. and Newsholme , E. A. 1982 . Effects of starvation on the maximal activities of some glycolytic and citric acid‐cycle enzymes and glutaminase in mucosa of the small intestine of the rat . Biochem. J. , 206 : 169 – 172 .
  • Bunner , D. L. and Morris , E. R. 1988 . Alteration of multiple cell membrane functions in L‐6 myoblasts by T‐2 toxin: an important mechanism of action . Toxicol. Appl. Pharmacol. , 92 : 113 – 121 .
  • Cebra , J. J. , Kamat , R. , Gearhart , P. , Robertson , S. M. and Tseng , J. 1977 . The secretory IgA system of the gut . Ciba Found. Symp. , 26 ( 46 ) : 5 – 28 .
  • Chacin , J. and Hernandez , I. 1995 . Interactions between oxoglutarate oxidation and acid‐secretion in isolated rabbit gastric glands . Exp. Physiol. , 80 : 441 – 448 .
  • Clausen , M. R. and Mortensen , P. B. 1994 . Kinetic studies on the metabolism of short‐chain fatty acids and glucose by isolated rat colonocytes . Gastroenterol. , 106 : 423 – 432 .
  • Cooney , G. J. , Taegtmeyer , H. and Newsholme , E. A. 1981 . Tricarboxylic acid cycle flux and enzyme activities in the isolated working rat heart . Biochem. J. , 200 : 701 – 703 .
  • Darcy‐Vrillon , B. , Morel , M. ‐T. , Cherbuy , C , Bernard , F. , Posho , L. , Blachier , F. , Meslin , J.‐C. and Duee , P.‐H. 1993 . Metabolic characteristics of pig colonocytes after adaptation to high fiber diet . J. Nutr. , 123 : 234 – 243 .
  • Denton , R. M. and McCormack , J. G. 1985 . Ca2+ transport by mammalian mitochondria and its role in hormone action . Am. J. Physiol. , 249 : E543 – E554 .
  • Elson , C. O. 1985 . Induction and control of the gastrointestinal immune system . Scand. J. Gastroenterol. Suppl. , 114 : 1 – 15 .
  • Evered , D. F. and Masola , B. 1984 . The oxidation of glutamine and glutamate in relation to anion transport in enterocyte mitochondria . Biochem. J. , 218 : 449 – 458 .
  • Fleming , S. E. , Fitch , M. D. , DeVries , S. , Liu , M. L. and Kight , C. 1991 . Nutrient utilization by cells isolated from rat jejunum, cecum and colon . J. Nutr. , 121 : 869 – 878 .
  • Forsyth , D. M. , Yoshizawa , T. , Morooka , N. and Tuite , J. 1977 . Emetic and refusal activity of deoxynivalenol to swine . Appl. Environ. Microbiol. , 34 : 547 – 552 .
  • Firmansyah , A. , Penn , D. and Lebenthal , E. 1989 . Isolated colonocyte metabolism of glucose, glutamine, n‐butyrate and ß‐hydroxybutyrate in malnutrition . Gastroenterol. , 97 : 622 – 629 .
  • Hedman , R. and Pettersson , H. 1996 . Purification and quantification of nivalenol . Mycotoxin Res. , 12 : 79 – 90 .
  • Hedman , R. , Pettersson , H. and Lindberg , J. E. 1997a . Absorption and metabolism of nivalenol in pigs . Arch. Anim. Nutr. , 50 : 13 – 24 .
  • Hedman , R. , Thuvander , A. , Gadhasson , I. , Reverter , M. and Pettersson , H. 1997b . Influence of dietary nivalenol exposure on gross pathology and selected immunological parameters in young pigs . Nat. Toxins. , 5 (6) : 238 – 246 .
  • Hinoshita , F. , Suzuki , Y. , Yokoyama , K. , Hara , S. , Yamada , A. , Ogura , Y. , Hashimoto , H. , Tomura , S. , Marumo , F. and Ueno , Y. 1997 . Experimental IgA nephropathy induced by a low dose environmental mycotoxin, nivalenol . Nephron. , 75 (4) : 469 – 478 .
  • Hulsmann , W. C. 1984 . “ Energy metabolism in small intestine ” . In Intestinal Toxicology , Edited by: Schiller , C. M. 57 – 67 . New York : Raven Press .
  • James , L. A. , Lunn , P. G. and Elia , M. 5th‐7th December 1995 . “ Glutaminase (EC 3.5.1.2) and glutamine synthetase (EC 6.3.1.2) activities in the gastrointestinal tract of humans ” . In Clinical metabolism and nutritional support group of the nutrition society and the British association for parenteral and enterai nutrition. Abstracts, PC 6, , 5th‐7th December , Eastbourne : The Devonshire Park Centre .
  • Kight , C. E. and Fleming , S. E. 1995 . Transamination processes promote incomplete glutamine oxidation in small intestine epithelial cells . Nutr. Biochem. , 6 : 27 – 37 .
  • Liener , I. E. 1990 . “ Naturally ocurring toxic factors in animal feedstuffs ” . In Feedstuff Evaluation. , 1st edn. , Edited by: Wiseman , J. and Cole , D. J. A. 377 – 394 . London : Butterworths .
  • Lowry , O. H. , Rosebrough , N. J. , Farr , A. L. and Randall , R. J. 1951 . Protein measurement with the Folin phenol reagent . J. Biol. Chem. , 193 : 265 – 275 .
  • Madej , M. , Lundh , T. and Lindberg , J. E. 1999 . Activities of enzymes involved in glutamine metabolism in connection with energy production in the gastrointestinal tract epithelium of new‐born, suckling and weaned piglets . Biol. Neonate. , 75 : 250 – 258 .
  • Patterson , D. S. , Matthews , J. G. , Shreeve , B. J. , Roberts , B. A. , McDonald , S. M. and Hayes , A. W. 1979 . The failure of trichothecene mycotoxins and whole cultures of Fusarium tricinctum to cause experimental heamorrhagic syndromes in calves and pigs . Vet. Rec. , 105 : 252 – 255 .
  • Pettersson , H. Trichothecene analysis in Swedish cereals 1987–1990 . Hod. Rosl. Aklim. Nasien. (Spec. Ed. Proc. 3rd European Seminar on Fusarium) . Vol. 37 , pp. 37 – 41 .
  • Pettersson , H. , Hedman , R. , Engström , B. , Elwinger , K. and Fossum , O. 1995 . Nivalenol in Swedish cereals‐occurrence, production and toxicity towards chickens . Food Addit. Contam. , 12 : 373 – 376 .
  • Rutter , G. A. and Denton , R. M. 1988 . Regulation of NAD+‐ linked isociträte dehydrogenase and 2‐ oxoglutarate dehydrogenase by Ca2+ ions within toluene‐permeabilized rat heart mitochondria. Interactions with regulation by adenine nucleotides and NADH/NAD+ ratios . Biochem. J. , 252 : 181 – 189 .
  • Schmidt , E. 1974 . “ Glutamate dehydrogenase, UV‐assay ” . In Methods of Enzymatic Analysis. , 2nd edn. , Edited by: Bergmeyer , H.‐U. Vol. 2 , 650 – 656 . London and New York : Academic Press .
  • Stryer , L. 1988 . “ Generation and storage of metabolic energy ” . In Biochemistry. , 3rd edn. Edited by: W. H. Freeman and Company . 313 – 543 . New York, , USA
  • Ueno , Y. 1983 . “ Effect of trichothecene mycotoxins on farm animals ” . In Trichothecenes. Chemical, Biological and Toxicological Aspects , Edited by: Ueno , Y. 135 – 146 . Amsterdam, , Netherland : Elsevier .
  • Watford , M. , Erbelding , E. J. and Smith , E. M. 1987 . The regulation of glutamine and ketone‐body metabolism in the small intestine of the long‐term (40‐day) streptozotocin‐diabetic rat . Biochem. J. , 242 : 61 – 68 .
  • Windmueller , H. G. and Spaeth , A. E. 1974 . Uptake and metabolism of plasma glutamine by the small intestine . J. Biol. Chem. , 249 : 5070 – 5079 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.