900
Views
20
CrossRef citations to date
0
Altmetric
Original

Reindeer BMP extract in the healing of critical-size bone defects in the radius of the rabbit

, , , &
Pages 952-959 | Received 18 Nov 2005, Accepted 10 Apr 2006, Published online: 08 Jul 2009

  • Barboza E P, Caula A L, Caula Fde O, de Souza R O, Geolas Neto L, Sorensen R G, Li X, Wikesjo U M. Effect of recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge with space-providing biomaterials on the augmentation of chronic alveolar ridge defects. J Periodontol 2004; 75: 702–8
  • Bax B E, Wozney J M, Ashhurst D E. Bone morphogenetic protein-2 increases the rate of callus formation after fracture of the rabbit tibia. Calcif Tissue Int 1999; 65: 83–9
  • Bessho K, Kusumoto K, Fujimura K, Konishi Y, Ogawa Y, Tani Y, Iizuka T Comparison of recombinant, purified human bone morphogenetic protein. Br J Oral Maxillofac Surg 1999; 37: 2–5
  • Blokhuis T J, den Boer F C, Bramer J A M, den Boer F C, Bakker F C, Patka P, Haarman H J, Manoliu R A. Biomechanical and histological aspects of fracture healing, stimulated with osteogenic protein-1. Biomaterials 2001; 22: 725–30
  • Burkus J K, Gornet M F, Dickman C A, Zdeblick T A. Anterior lumbar interbody fusion using rhBMP-2 with tapered interbody cages. J Spinal Disord Tech 2002a; 15: 337–49
  • Burkus J K, Transfeldt E E, Kitchel S H, Watkins R G, Balderston R A. Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2. Spine 2002b; 27: 2396–408
  • Chen X, Kidder L S, Lew W D. Osteogenic protein-1 induced bone formation in an infected segmental defect in the rat femur. J Orthop Res 2002; 20: 142–50
  • Cheng H, Jiang W, Phillips F M, Haydon R C, Peng Y, Zhou L, Luu H H, An N, Breyer B, Vanichakarn P, Szatkowski J P, Park J Y, He T C. Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg (Am) 2003; 85: 1544–52
  • Cook S D. Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites. Orthopaedics 1999; 22: 669–71
  • Einhorn T A, Majeska R J, Mohaideen A, Kagel E M, Bouxsein M L, Turek T J, Wozney J M. A single percutaneous injection of recombinant human bone morphogenetic pro-tein-2 accelerates fracture repair. J Bone Joint Surg (Am) 2003; 85: 1425–35
  • Gao T J, Lindholm T S, Kommonen B, Ragni P, Paronzini A, Lindholm T C, Jämsä T, Jalovaara P. Enhanced healing of segmental tibial defects in sheep by a composite bone substitute composed of tricalcium phosphate cylinder, bone morphogenetic protein, and type IV collagen. J Biomed Mater Res 1996; 32: 505–12
  • Gao T J, Lindholm T S, Kommonen B, Ragni P, Paronzini A, Lindholm T C, Jalovaara P, Uris M R. The use of a coral composite implant containing bone morphogenetic protein to repair a segmental tibial defect in sheep. Int Orthop 1997; 21: 194–200
  • Govender S, Csimma C, Genant H K, Valentin-Opran A. Recombinant human bone morphogenetic protein2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg (Am) 2002; 84: 2123–34
  • Hollinger J O, Schmitt J M, Buck D C, Shannon R, Joh S P, Zegzula H D, Wozney J. Recombinant human bone morphogenetic protein-2 and collagen for bone regeneration. J Biomed Mater Res 1998; 43: 356–64
  • Hu Y, Zhang C, Zhang S, Xiong Z, Xu J. Development of a porous poly(L-lactic acid)/hydroxyapatite/collagen scaffold as a BMP delivery system and its use in healing canine segmental bone defect. J Biomed Mater Res 2003; 67A: 591–8
  • Jämsä T, Jalovaara P. A cost-effective, accurate machine for testing the torsional strength of sheep long bones. Med Eng Phys 1996; 18: 433–5
  • Jortikka L, Marttinen A, Lindholm T S. Partially purified reindeer (Rangifer Tarandus) bone morphogenetic protein has a high bone-forming activity compared with some other artiodactylis. Clin Orthop 1993a, 297: 33–7
  • Jortikka L, Marttinen A, Lindholm T S. Purification of monocomponent bovine morphogenetic protein in a water-soluble form. Ann Chir Gyn 1993b; 82: 25–30
  • Kokubo S, Fujimoto R, Yokota S. Bone regeneration by recombinant human bone morphogenetic protein-2 and a novel biodegradable carrier in a rabbit ulnar defect model. Biomaterials 2003; 24: 1643–51
  • Lepola V, Väänänen K, Jalovaara P. The effect of immobilization on the torsional strength of the rat tibia. Clin Orthop 1993, 297: 55–61
  • Li G, Bouxsein M L, Luppen C, Li X J, Wood M, Seeherman H J, Wozney J M, Simpson H. Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis. J Orthop Res 2002; 20: 779–88
  • Matsuo T, Sugita T, Kubo T, Yasunaga Y, Ochi M, Murakami T. Injectable magnetic liposomes as a novel carrier of recombinant human BMP-2 for bone formation in a rat bone-defect model. J Biomed Mater Res 2003; 66A: 747–54
  • Miekka S I, Forng R Y, Rohwer R G, MacAuley C, Stafford R E, Flack S L, MacPhee M, Kent R S, Drohan W N. Inactivation of viral and prion pathogens by gammairradiation under conditions that maintain the integrity of human albumin. Vox Sang 2003; 84: 36–44
  • Moore J C, Matukas V J, Deatherage J R, Miller E J. Craniofacial osseous restoration with osteoinductive proteins in a collagenous delivery system. Int J Oral Maxillofac Surg 1990; 19: 172–6
  • Pekkarinen T, Lindholm T S, Hietala O, Jalovaara P. New bone formation induced by injection of native reindeer BMP. Scand J Surg 2003; 92: 227–30
  • Pekkarinen T, Lindholm T S, Hietala O, Jalovaara P. Influence of ethylene oxide sterilization on the activity of native reindeer bone morphogenetic protein. Int Orthop 2004; 28: 97–101
  • Pekkarinen T, Lindholm T S, Hietala O, Jalovaara P. The effect of different mineral frames on the ectopic bone formation in mouse hind leg muscles induced by native reindeer bone morphogenetic protein. Arch Orthop Trauma Surg 2005a; 125: 10–5
  • Pekkarinen T, Hietala O, Jämsä T, Jalovaara P. Effect of gamma irradiation on the osteoinductivity of native reindeer bone morphogenetic protein extract. Acta Orthop 2005b; 76: 231–6
  • Pekkarinen T, Hietala O, Jämsä T, Jalovaara P. Gamma irradiation and ethylene oxide in the sterilization of native reindeer bone morphogenetic protein extract. Scand J Surg 2005c; 94: 67–70
  • Sciadini M F, Dawson J M, Johnson K D. Bovine-derived bone protein as a bone graft substitute in a canine segmental defect model. J Orthop Trauma 1997; 11: 496–508
  • Sciadini M F, Johnson K D. Evaluation of recombinant human bone morphogenetic protein-2 as a bone-graft substitute in a canine segmental defect model. J Orthop Res 2000; 18: 289–302
  • Takagi K, Urist M R. The role of bone marrow in bone morphogenetic protein-induced repair of femoral massive diaphyseal defects. Clin Orthop 1982, 171: 224–31
  • Tuominen T, Jämsä T, Tuukkanen J, Nieminen P, Lindholm T C, Lindholm T S, Jalovaara P. Native bovine bone morphogenetic protein improves the potential of biocoral to heal segmental canine ulnar defects. Int Orthop 2000; 24: 289–94
  • Tuominen T, Jämsä T, Oksanen J, Tuukkanen J, Gao T J, Lindholm T S, Jalovaara P. Composite implant composed of hydroxyapatite and bone morphogenetic protein in the healing of a canine ulnar defect. Ann Chir Gynaecol 2001; 90: 32–6
  • Valentin-Opran A, Wozney J, Csimma C, Lilly L, Riedel G E. Clinical evaluation of recombinant human bone morphogenetic protein-2. Clin Orthop 2002, 39: 5110–20
  • Viljanen V V, Gao T J, Lindholm T C, Lindholm T S, Kommonen B. Xenogeneic moose (Alces alces) bone morphogenetic protein (mBMP)-induced repair of critical-size skull defects in sheep. Int J Oral Maxillofac Surg 1996; 25: 217–22
  • Wozney J M. Overview of bone morphogenetic proteins. Spine 2002; 27: S2–8
  • Yudell R M, Block M S. Bone gap healing in the dog using recombinant human bone morphogenetic-2. J Oral Maxillofac Surg 2000; 58: 761–6

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.