3,776
Views
116
CrossRef citations to date
0
Altmetric
Original papers

Metal-on-metal hip resurfacing arthroplasty: A review of periprosthetic biological reactions

, , , &
Pages 734-747 | Received 28 Nov 2007, Accepted 05 Aug 2008, Published online: 08 Jul 2009

  • Allen M J, et al. The effects of particulate cobalt, chromium and cobalt-chromium alloy on human osteoblast-like cells in vitro. J Bone Joint Surg (Br) 1997; 79: 475–82
  • Amstutz H C, et al. Resurfacing THA for patients younger than 50 year: results of 2- to 9-year followup. Clin Orthop 2007, 460: 159–64
  • Anissian L, et al. Cobalt ions influence proliferation and function of human osteoblast-like cells. Acta Orthop Scand 2002; 73: 369–74
  • Arslan P, et al. Intracellular chromium reduction. Biochim Biophys Acta 1987; 931: 10–5
  • Back D L, et al. Early results of primary Birmingham hip resurfacings. An independent prospective study of the first 230 hips. J Bone Joint Surg (Br) 2005a; 87: 324–9
  • Back D L, et al. How do serum cobalt and chromium levels change after metal-on-metal hip resurfacing?. Clin Orthop 2005b, 438: 177–81
  • Bacon B R, et al. Hepatic lipid peroxidation in vivo in rats with chronic iron overload. J Clin Invest 1983; 71: 429–39
  • Bar-Or D, et al. Characterization of the Co(2+) and Ni(2+) binding amino-acid residues of the N-terminus of human albumin. An insight into the mechanism of a new assay for myocardial ischemia. Eur J Biochem 2001; 268: 42–7
  • Beaule P E, et al. Risk factors affecting outcome of metal-on-metal surface arthroplasty of the hip. Clin Orthop 2004a; 87–93, [no.??)]:
  • Beaule P E, et al. Metal-on-metal surface arthroplasty with a cemented femoral component: a 7-10 year follow-up study. J Arthroplasty s2004b; 19: 17–22
  • Bell R S, et al. A study of implant failure in the Wagner resurfacing arthroplasty. J Bone Joint Surg (Am) 1985; 67: 1165–75
  • Boardman D R, et al. A benign psoas mass following metal-on-metal resurfacing of the hip. J Bone Joint Surg (Br) 2006; 88: 402–4
  • Borguet F, et al. Study of the chromium binding in plasma of patients on continuous ambulatory peritoneal dialysis. Clin Chim Acta 1995; 238: 71–84
  • Brodner W, et al. Serum cobalt levels after metal-on-metal total hip arthroplasty. J Bone Joint Surg (Am) 2003; 85: 2168–73
  • Brodner W, et al. Does the placenta inhibit the passage of chromium and cobalt after metal-on-metal total hip arthroplasty?. J Arthroplasty 2004a; 19: 102–6
  • Brodner W, et al. Cup inclination and serum concentration of cobalt and chromium after metal-on-metal total hip arthroplasty. J Arthroplasty 2004b; 19: 66–70
  • Buergi M L, Walter W L. Hip resurfacing arthroplasty: the Australian experience. J Arthroplasty 2007; 22: 61–5
  • Buschner G, et al. Subsurface microstructure of metal-on-metal hip joints and its relationship to wear particle generation. J Biomed Mater Res 2004; 72B: 206–14
  • Buttner B, Beyersmann D. Modification of the erythrocyte anion carrier by chromate. Xenobiotica 1985; 15: 735–41
  • Campbell P, et al. Isolation of predominantly submicron-sized UHMWPE wear particles from periprosthetic tissues. J Biomed Mater Res 1995; 29: 127–31
  • Campbell P, et al. Wear and morphology of ultra-high molec ular weight polyethylene wear particles from total hip replacements. Proc Inst Mech Eng [H] 1996; 210: 167–74
  • Case C P, et al. Preliminary observations on possible premalignant changes in bone marrow adjacent to worn total hip arthroplasty implants. Clin Orthop 1996, 329: S269–79
  • Clarke M T, et al. Levels of metal ions after small- and large-diameter metal-on-metal hip arthroplasty. J Bone Joint Surg (Br) 2003; 85: 913–7
  • Clodfelder B J, et al. The trail of chromium(III) in vivo from the blood to the urine: the roles of transferrin and chromodulin. J Biol Inorg Chem 2001; 6: 608–17
  • Cobb A G, Schmalzreid T P. The clinical significance of metal ion release from cobalt-chromium metal-on-metal hip joint arthroplasty. Proc Inst Mech Eng [H] 2006; 220: 385–98
  • Coleman R F, et al. Concentration of wear products in hair, blood, and urine after total hip replacement. Br Med J 1973; 1: 527–9
  • Daniel J, et al. Metal-on-metal resurfacing of the hip in patients under the age of 55 years with osteoarthritis. J Bone Joint Surg (Br) 2004; 86: 177–84
  • Daniel J, et al. The effect of the diameter of metal-on-metal bearings on systemic exposure to cobalt and chromium. J Bone Joint Surg (Br) 2006; 88: 443–8
  • Daniel J, et al. The validity of serum levels as a surrogate measure of systemic exposure to metal ions in hip replacement. J Bone Joint Surg (Br) 2007; 89: 736–41
  • Davies A P, et al. An unusual lymphocytic perivascular infiltration in tissues around contemporary metal-on-metal joint replacements. J Bone Joint Surg (Am) 2005; 87: 18–27
  • De Smet K A. Belgium experience with metal-on-metal surface arthroplasty. Orthop Clin North Am 2005; 36: 20313, ix
  • Dizdaroglu M, et al. Free radical-induced damage to DNA: mechanisms and measurement. Free Radic Biol Med 2002; 32: 1102–15
  • Doherty A T, et al. Increased chromosome translocations and aneuploidy in peripheral blood lymphocytes of patients having revision arthroplasty of the hip. J Bone Joint Surg (Br) 2001; 83: 1075–81
  • Doorn P F, et al. Tissue reaction to metal on metal total hip prostheses. Clin Orthop 1996, 329: S187–205
  • Doorn P F, et al. Metal wear particle characterization from metal on metal total hip replacements: transmission electron microscopy study of periprosthetic tissues and isolated particles. J Biomed Mater Res 1998; 42: 103–11
  • Dumbleton J H, et al. A literature review of the association between wear rate and osteolysis in total hip arthroplasty. J Arthroplasty 2002; 17: 649–61
  • Eitinger T, et al. Secondary transporters for nickel and cobalt ions: theme and variations. Biometals 2005; 18: 399–405
  • Eshaghi S, et al. Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution. Science 2006; 313: 354–7
  • Fernandes M H. Effect of stainless steel corrosion products on in vitro biomineralization. J Biomater Appl 1999; 14: 113–68
  • Fleury C, et al. Effect of cobalt and chromium ions on human MG-63 osteoblasts in vitro: morphology, cytotoxicity, and oxidative stress. Biomaterials 2006; 27: 3351–60
  • Galle P, et al. Role of alveolar macrophages in precipitation of mineral elements inhaled as soluble aerosols. Environ Health Perspect 1992; 97: 145–7
  • Gillespie W J, et al. Development of hematopoietic cancers after implantation of total joint replacement. Clin Orthop 1996, 329: S290–6
  • Goodman S B, et al. In vitro, in vivo, and tissue retrieval studies on particulate debris. Clin Orthop 1998, 352: 25–34
  • Green T R, et al. Polyethylene particles of a ‘critical size’ are necessary for the induction of cytokines by macrophages in vitro. Biomaterials 1998; 19: 2297–302
  • Grigoris P, et al. The evolution of hip resurfacing arthroplasty. Orthop Clin North Am 2005; 36: 125–34, vii
  • Gruber F W, et al. Cystic lesion of the groin due to metallosis: a rare long-term complication of metal-on-metal total hip arthroplasty. J Arthroplasty 2007; 22: 923–7
  • Hallab N J, et al. A triple assay technique for the evaluation of metal-induced, delayed-type hypersensitivity responses in patients with or receiving total joint arthroplasty. J Biomed Mater Res 2000; 53: 480–9
  • Hallab N, et al. Metal sensitivity in patients with orthopaedic implants. J Bone Joint Surg (Am) 2001; 83: 428–36
  • Hallab N J, et al. Concentration- and composition-depen-dent effects of metal ions on human MG-63 osteoblasts. J Biomed Mater Res 2002; 60: 420–33
  • Hallab N J, et al. Lymphocyte responses in patients with total hip arthroplasty. J Orthop Res 2005; 23: 384–91
  • Harris W H. The problem is osteolysis. Clin Orthop 1995, 311: 46–53
  • Hart A J, et al. The association between metal ions from hip resurfacing and reduced T-cell counts. J Bone Joint Surg (Br) 2006; 88: 449–54
  • Hartwig A, et al. Modulation of DNA repair processes by arsenic and selenium compounds. Toxicology 2003; 193: 161–9
  • Head W C. Wagner surface replacement arthroplasty of the hip. Analysis of fourteen failures in forty-one hips. J Bone Joint Surg (Am) 1981; 63: 420–7
  • Heisel C, et al. The relationship between activity and ions in patients with metal-on-metal bearing hip prostheses. J Bone Joint Surg (Am) 2005; 87: 781–7
  • Hing C B, et al. The results of primary Birmingham hip resurfacings at a mean of five years: An independent prospective review of the first 230 hips. J Bone Joint Surg (Br) 2007; 89: 1431–8
  • Hodges N J, Chipman J K. Down-regulation of the DNA-repair endonuclease 8-oxo-guanine DNA glycosylase 1 (hOGG1) by sodium dichromate in cultured human A549 lung carcinoma cells. Carcinogenesis 2002; 23: 55–60
  • Howie D W, Vernon-Roberts B. Long-term effects of intraarticular cobalt-chrome alloy wear particles in rats. J Arthroplasty 1988; 3: 327–36
  • Howie D W, et al. The long-term wear of retrieved McKee-Farrar metal-on-metal total hip prostheses. J Arthroplasty 2005; 20: 350–7
  • Jacobs J J, et al. Cobalt and chromium concentrations in patients with metal on metal total hip replacements. Clin Orthop 1996, 329: S256–63
  • Jacobs J J, et al. Metal release in patients who have had a primary total hip arthroplasty. A prospective, controlled, longitudinal study. J Bone Joint Surg (Am) 1998; 80: 1447–58
  • Jakobsen S S, et al. Cobalt-chromium-molybdenum alloy causes metal accumulation and metallothionein up-regu-lation in rat liver and kidney. Basic Clin Pharmacol Toxicol 2007; 101: 441–6
  • Kadoya Y, et al. Wear and osteolysis in total joint replacements. Acta Orthop Scand 1998, Suppl 278: 1–16
  • Keegan G M, et al. Orthopaedic metals and their potential toxicity in the arthroplasty patient: A review of current knowledge and future strategies. J Bone Joint Surg (Br) 2007; 89: 567–73
  • Kobayashi A, et al. The size and shape of particulate polyethylene wear debris in total joint replacements. Proc Inst Mech Eng [H] 1997a; 211: 11–5
  • Kobayashi A, et al. Number of polyethylene particles and osteolysis in total joint replacements. A quantitative study using a tissue-digestion method. J Bone Joint Surg (Br) 1997b; 79: 844–8
  • Kudo O, et al. Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. Bone 2003; 32: 1–7
  • Ladon D, et al. Changes in metal levels and chromosome aberrations in the peripheral blood of patients after metal-on-metal hip arthroplasty. J Arthroplasty 2004; 19: 78–83
  • Lhotka C, et al. Four-year study of cobalt and chromium blood levels in patients managed with two different metal-on-metal total hip replacements. J Orthop Res 2003; 21: 189–95
  • Lidgren L. Chronic inflammation, joint replacement and malignant lymphoma. J Bone Joint Surg (Br) 2008; 90: 7–10
  • Lilikakis A K, et al. Hydroxyapatite-coated femoral implant in metal-on-metal resurfacing hip arthroplasty: minimum of two years follow-up. Orthop Clin North Am 2005; 36: 215–22, ix
  • Lundborg M, et al. Phagolysosomal pH and dissolution of cobalt oxide particles by alveolar macrophages. Environ Health Perspect 1992; 97: 153–7
  • Mabilleau G, et al. Influence of fluoride, hydrogen peroxide and lactic acid on the corrosion resistance of commercially pure titanium. Acta Biomater 2006; 2: 121–9
  • MacDonald S J, et al. Metal-on-metal versus polyethylene in hip arthroplasty: a randomized clinical trial. Clin Orthop 2003, 406: 282–96
  • MacQuarrie R A, et al. Wear-particle-induced osteoclast osteolysis: the role of particulates and mechanical strain. J Biomed Mater Res B Appl Biomater 2004; 69: 104–12
  • Madan S, et al. Recurrent intrapelvic cyst complicating metal-on-metal cemented total hip arthroplasty. Arch Orthop Trauma Surg 2000; 120: 508–10
  • Maloney W J, et al. Fixation, polyethylene wear, and pelvic osteolysis in primary total hip replacement. Clin Orthop 1999, 369: 157–64
  • Margevicius K J, et al. Isolation and characterization of debris in membranes around total joint prostheses. J Bone Joint Surg (Am) 1994; 76: 1664–75
  • Marker M, et al. Metal-on-metal hip implants: do they impair renal function in the long-term? A 10-year follow-up study. Arch Orthop Trauma Surg 2007; 128: 915–9
  • Marnett L J. Lipid peroxidation-DNA damage by malondialdehyde. Mutat Res 1999; 424: 83–95
  • McKay G C, et al. Interactions of orthopaedic metals with an immortalized rat osteoblast cell line. Biomaterials 1996; 17: 1339–44
  • McKellop H, et al. In vivo wear of three types of metal on metal hip prostheses during two decades of use. Clin Orthop 1996, 329: S128–40
  • Mont M A, et al. Resurfacing hip arthroplasty: comparison of a minimally invasive versus standard approach. Clin Orthop Relat Res 2005; 441: 125–31
  • Mont M A, et al. Use of metal-on-metal total hip resurfacing for the treatment of osteonecrosis of the femoral head. J Bone Joint Surg (Am) 2006; 88(Suppl 3)90–7
  • Morais S, et al. In vitro biomineralization by osteoblast-like cells. I. Retardation of tissue mineralization by metal salts. Biomaterials 1998; 19: 13–21
  • National joint registry England and Wales annual report. http:www.njrventre.org.uk/Public/prev_annual_reports.htm 2008
  • Nichols K G, Puleo D A. Effect of metal ions on the formation and function of osteoclastic cells in vitro. J Biomed Mater Res 1997; 35: 265–71
  • Nishii T, et al. Five-year results of metal-on-metal resurfacing arthroplasty in Asian patients. J Arthroplasty 2007; 22: 176–83
  • The Norwegian Arthroplasty Register. http://www.hauke-land.no/nrl 2007
  • Pandit H, et al. Pseudotumours associated with metal-on- metal hip resurfacings. J Bone Joint Surg (Br) 2008; 90: 847–51
  • Papageorgiou I, et al. The effect of nano- and micron-sized particles of cobalt-chromium alloy on human fibroblasts in vitro. Biomaterials 2007; 28: 2946–58
  • Park Y S, et al. Early osteolysis following second-generation metal-on-metal hip replacement. J Bone Joint Surg (Am) 2005; 87: 1515–21
  • Qian Z M, et al. Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol Rev 2002; 54: 561–87
  • Rae T. The macrophage response to implant materials. Crit Rev Biocompatibility 1986; 2: 97–126
  • Rasquinha V J, et al. Serum metal levels and bearing surfaces in total hip arthroplasty. J Arthroplasty 2006; 21: 47–52
  • Revell M P, et al. Metal-on-metal hip resurfacing in osteonecrosis of the femoral head. J Bone Joint Surg (Am) 2006; 88(Suppl 3)98–103
  • Robey P, Boskey A. Extracellular matrix and biomineralization. Primer on the metabolic bone diseases and disorders of mineral metabolism, J Lian, S Goldring. American Society for Bone and Mineral Research, Washington DC 2006; 12–9
  • Rousselle A V, et al. Influence of metal ion solutions on rabbit osteoclast activities in vitro. Histol Histopathol 2002; 17: 1025–32
  • Savarino L, et al. Ion release in patients with metal-on-metal hip bearings in total joint replacement: a comparison with metal-on-polyethylene bearings. J Biomed Mater Res 2002; 63: 467–74
  • Schmalzried T P, et al. Periprosthetic bone loss in total hip arthroplasty. Polyethylene wear debris and the concept of the effective joint space. J Bone Joint Surg (Am) 1992; 74: 849–63
  • Shanbhag A S, et al. Composition and morphology of wear debris in failed uncemented total hip replacement. J Bone Joint Surg (Br) 1994; 76: 60–7
  • Shimmin A, et al. Metal-on-metal hip resurfacing arthroplasty. J Bone Joint Surg (Am) 2008; 90: 637–54
  • Shimmin A J, Back D. Femoral neck fractures following Birmingham hip resurfacing: a national review of 50 cases. J Bone Joint Surg (Br) 2005; 87: 463–4
  • Shimmin A J, et al. Complications associated with hip resurfacing arthroplasty. Orthop Clin North Am 2005; 36: 18793, ix
  • Sieber H P, et al. Analysis of 118 second-generation metal-on-metal retrieved hip implants. J Bone Joint Surg (Br) 1999; 81: 46–50
  • Sochart D H. Relationship of acetabular wear to osteolysis and loosening in total hip arthroplasty. Clin Orthop 1999, 363: 135–50
  • Steffen R T, et al. The five-year results of the Birmingham Hip Resurfacing arthroplasty: An independent series. J Bone Joint Surg (Br) 2008; 90: 436–41
  • Sun H, et al. Transferrin as a metal ion mediator. Chem Rev 1999; 99: 2817–42
  • Swedish Hip Arthroplasty Register. http://www.jru.orthop.gu.se 2006
  • Toms A P, et al. MRI of early symptomatic metal-on-metal total hip arthroplasty: a retrospective review of radiological findings in 20 hips. Clin Radiol 2008; 63: 49–58
  • Torti S V, Torti F M. Iron and ferritin in inflammation and cancer. Adv Inorg Biochem 1994; 10: 119–37
  • Treacy R B, et al. Birmingham hip resurfacing arthroplasty. A minimum follow-up of five years. J Bone Joint Surg (Br) 2005; 87: 167–70
  • Vendittoli P A, et al. Chromium and cobalt ion release following the Durom high carbon content, forged metal-on-metal surface replacement of the hip. J Bone Joint Surg (Br) 2007; 89: 441–8
  • Virginio C, et al. Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor. Neuropharmacology 1997; 36: 1285–94
  • Wang J Y, et al. Prosthetic metals impair murine immune response and cytokine release in vivo and in vitro. J Orthop Res 1997; 15: 688–99
  • Willert H G, et al. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg (Am) 2005; 87: 28–36
  • Witkiewicz-Kucharczyk A, Bal W. Damage of zinc fingers in DNA repair proteins, a novel molecular mechanism in carcinogenesis. Toxicol Lett 2006; 162: 29–42
  • Witzleb W C, et al. Neo-capsule tissue reactions in metal-on-metal hip arthroplasty. Acta Orthop 2007; 78: 211–20
  • Wolf T, et al. Molecular interaction of different chromium species with nucleotides and nucleic acids. Carcinogenesis 1989; 10: 655–9
  • Ziaee H, et al. Transplacental transfer of cobalt and chro mium in patients with metal-on-metal hip arthroplasty: a controlled study. J Bone Joint Surg (Br) 2007; 89: 301–5

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.